New Positions
78 managers initiated
Top five by reported value
Scholar Rock Holding Corp NASDAQ NMS - GLOBAL MARKET:SRRK
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
78 new95 added105 reduced47 exited
Total Institutional Holders
277
as of 2025-12-31
Top Holder
FMR LLC
$677.5M
Largest QoQ Increase
Orbis Allan Gray Ltd
+3,126,677 sh
Largest QoQ Decrease
ADAGE CAPITAL PARTNERS GP, L.L.C.
-1,951,866 sh
New Positions(78)
Added To(95)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| FMR LLC | 15,380,675 | +1,368,597 | $677.5M | +$155.7M | 9.8% |
| Orbis Allan Gray Ltd | 3,428,929 | +3,126,677 | $151.0M | +$139.8M | 1034.5% |
| Siren, L.L.C. | 10,825,013 | +1,575,008 | $476.8M | +$132.4M | 17.0% |
| Samsara BioCapital, LLC | 6,897,652 | +1,284,756 | $303.8M | +$94.8M | 22.9% |
| Redmile Group, LLC | 5,220,846 | +1,316,390 | $230.0M | +$84.6M | 33.7% |
| WELLINGTON MANAGEMENT GROUP LLP | 5,759,428 | +1,213,541 | $253.7M | +$84.4M | 26.7% |
| NORGES BANK | 2,079,515 | +349,411 | $91.6M | +$77.7M | 20.2% |
| BlackRock, Inc. | 7,217,034 | +456,847 | $317.9M | +$66.2M | 6.8% |
| JENNISON ASSOCIATES LLC | 2,795,188 | +1,188,676 | $123.1M | +$63.3M | 74.0% |
| Paradigm Biocapital Advisors LP | 3,062,157 | +1,052,412 | $134.9M | +$60.0M | 52.4% |
| Bellevue Group AG | 4,056,592 | +812,055 | $178.7M | +$57.9M | 25.0% |
| VANGUARD GROUP INC | 5,195,465 | +280,538 | $228.9M | +$45.8M | 5.7% |
| STATE STREET CORP | 4,034,434 | +271,331 | $177.7M | +$37.6M | 7.2% |
| Polar Capital Holdings Plc | 1,322,011 | +527,929 | $58.2M | +$28.7M | 66.5% |
| BNP PARIBAS ARBITRAGE, SNC | 554,602 | +534,278 | $24.4M | +$23.7M | 2628.8% |
| Woodline Partners LP | 1,211,088 | +340,038 | $53.3M | +$20.9M | 39.0% |
| BANK OF AMERICA CORP /DE/ | 1,050,506 | +316,903 | $46.3M | +$19.0M | 43.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 2,034,024 | +79,214 | $89.6M | +$16.8M | 4.0% |
| Hood River Capital Management LLC | 2,026,758 | +12,365 | $89.3M | +$14.3M | 0.6% |
| Ensign Peak Advisors, Inc | 835,851 | +183,615 | $36.8M | +$12.5M | 28.1% |
| STEMPOINT CAPITAL LP | 1,163,893 | +419,289 | $39.6M | +$12.5M | 56.3% |
| TWO SIGMA INVESTMENTS, LP | 405,523 | +246,455 | $17.9M | +$11.9M | 154.9% |
| AQR CAPITAL MANAGEMENT LLC | 280,324 | +259,148 | $12.3M | +$11.6M | 1223.8% |
| NAN FUNG TRINITY (HK) LTD | 263,245 | +225,603 | $11.6M | +$10.2M | 599.3% |
| Integral Health Asset Management, LLC | 300,000 | +200,000 | $13.2M | +$9.5M | 200.0% |
| CITADEL ADVISORS LLC | 573,946 | +144,436 | $25.3M | +$9.3M | 33.6% |
| Nuveen, LLC | 604,417 | +110,254 | $26.6M | +$8.2M | 22.3% |
| Man Group plc | 182,024 | +147,842 | $8.0M | +$6.7M | 432.5% |
| Voya Investment Management LLC | 514,224 | +71,069 | $22.7M | +$6.1M | 16.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 702,095 | +25,060 | $30.9M | +$5.7M | 3.7% |
| AMERICAN CENTURY COMPANIES INC | 708,253 | +22,289 | $31.2M | +$5.7M | 3.2% |
| NOMURA HOLDINGS INC | 110,800 | +80,344 | $4.9M | +$3.7M | 263.8% |
| DEUTSCHE BANK AG\ | 226,168 | +28,982 | $10.0M | +$2.6M | 14.7% |
| TUDOR INVESTMENT CORP ET AL | 65,017 | +56,917 | $2.9M | +$2.6M | 702.7% |
| ADAR1 Capital Management, LLC | 69,589 | +49,502 | $3.1M | +$2.3M | 246.4% |
| RAYMOND JAMES FINANCIAL INC | 245,387 | +17,236 | $10.8M | +$2.3M | 7.5% |
| WELLS FARGO & COMPANY/MN | 90,553 | +39,265 | $4.0M | +$2.1M | 76.5% |
| Granahan Investment Management, LLC | 153,769 | +23,855 | $6.8M | +$1.9M | 18.4% |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 168,547 | +8,806 | $7.4M | +$1.5M | 5.5% |
| J. Goldman & Co LP | 60,100 | +21,763 | $2.6M | +$1.2M | 56.8% |
| Invesco Ltd. | 82,462 | +14,291 | $3.6M | +$1.1M | 21.0% |
| GUGGENHEIM CAPITAL LLC | 28,886 | +22,598 | $1.3M | +$1.0M | 359.4% |
| PROFUND ADVISORS LLC | 48,152 | +17,501 | $2.1M | +$979.7K | 57.1% |
| Swiss National Bank | 123,200 | +3,600 | $5.4M | +$973.1K | 3.0% |
| SEI INVESTMENTS CO | 120,527 | +3,218 | $5.3M | +$940.7K | 2.7% |
| DNB Asset Management AS | 35,059 | +13,544 | $1.5M | +$743.1K | 63.0% |
| StoneCrest Wealth Management, Inc. | 59,003 | +11,671 | $2.5M | +$731.3K | 24.6% |
| KENNEDY CAPITAL MANAGEMENT LLC | 62,678 | +844 | $2.8M | +$458.3K | 1.4% |
| INTECH INVESTMENT MANAGEMENT LLC | 32,847 | +4,334 | $1.4M | +$385.1K | 15.2% |
| FRANKLIN RESOURCES INC | 41,772 | +2,303 | $1.8M | +$370.2K | 5.8% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 45,798 | +993 | $2.0M | +$337.5K | 2.2% |
| China Universal Asset Management Co., Ltd. | 21,622 | +4,772 | $952.4K | +$325.0K | 28.3% |
| Mariner, LLC | 15,849 | +5,849 | $697.2K | +$324.8K | 58.5% |
| FARALLON CAPITAL MANAGEMENT LLC | 14,000 | +7,000 | $569.0K | +$308.4K | 100.0% |
| Creative Planning | 27,131 | +3,127 | $1.2M | +$301.2K | 13.0% |
| POLEN CAPITAL MANAGEMENT LLC | 21,762 | +3,702 | $958.6K | +$286.1K | 20.5% |
| Knott David M Jr | 13,913 | +4,913 | $612.9K | +$277.7K | 54.6% |
| VERUS CAPITAL PARTNERS, LLC | 22,100 | +3,330 | $973.5K | +$274.5K | 17.7% |
| Mill Creek Capital Advisors, LLC | 12,500 | +5,000 | $550.6K | +$271.3K | 66.7% |
| CITIGROUP INC | 20,110 | +2,800 | $885.8K | +$241.2K | 16.2% |
| ProShare Advisors LLC | 19,545 | +2,236 | $861.0K | +$216.4K | 12.9% |
| Allianz Asset Management GmbH | 9,400 | +3,900 | $414.1K | +$209.3K | 70.9% |
| Longaeva Partners L.P. | 27,006 | +620 | $1.2M | +$207.0K | 2.3% |
| LPL Financial LLC | 17,523 | +1,822 | $771.9K | +$187.2K | 11.6% |
| Tower Research Capital LLC (TRC) | 8,210 | +2,838 | $361.6K | +$161.6K | 52.8% |
| KLP KAPITALFORVALTNING AS | 13,300 | +1,000 | $585.9K | +$127.8K | 8.1% |
| Virtus Investment Advisers, Inc. | 5,676 | +2,261 | $250.0K | +$122.9K | 66.2% |
| M&T Bank Corp | 10,021 | +1,320 | $441.9K | +$118.1K | 15.2% |
| MN Wealth Advisors, LLC | 8,155 | +959 | $359.2K | +$91.2K | 13.3% |
| NEOS Investment Management LLC | 9,899 | +616 | $436.1K | +$90.4K | 6.6% |
| TEMA ETFS LLC | 9,899 | +616 | $436.1K | +$90.4K | 6.6% |
| Three Seasons Wealth, LLC | 10,968 | +222 | $483.1K | +$83.0K | 2.1% |
| Mirae Asset Global Investments Co., Ltd. | 4,957 | +1,241 | $218.4K | +$80.0K | 33.4% |
| AlphaQuest LLC | 4,440 | +1,025 | $195.6K | +$68.4K | 30.0% |
| SYON CAPITAL LLC | 9,170 | +30 | $403.9K | +$63.6K | 0.3% |
| STRS OHIO | 2,700 | +1,000 | $118.9K | +$55.6K | 58.8% |
| XPONANCE, INC. | 6,493 | +108 | $286.0K | +$48.2K | 1.7% |
| ADVISOR GROUP HOLDINGS, INC. | 3,318 | +665 | $146.2K | +$47.6K | 25.1% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 829,422 | +828,843 | $36.5K | +$36.5K | 143150.8% |
| EverSource Wealth Advisors, LLC | 872 | +525 | $38.4K | +$25.5K | 151.3% |
| Farther Finance Advisors, LLC | 438 | +386 | $19.3K | +$17.4K | 742.3% |
| Sterling Capital Management LLC | 885 | +249 | $39.0K | +$15.3K | 39.1% |
| Rockefeller Capital Management L.P. | 451 | +296 | $19.9K | +$14.1K | 191.0% |
| GAMMA Investing LLC | 1,006 | +170 | $44.3K | +$13.2K | 20.3% |
| Smartleaf Asset Management LLC | 462 | +140 | $20.2K | +$7.8K | 43.5% |
| PNC Financial Services Group, Inc. | 660 | +67 | $29.1K | +$7.0K | 11.3% |
| ROTHSCHILD INVESTMENT LLC | 204 | +104 | $9.0K | +$5.3K | 104.0% |
| Global Retirement Partners, LLC | 163 | +66 | $7.2K | +$3.6K | 68.0% |
| SG Americas Securities, LLC | 84,349 | +72,341 | $3.7K | +$3.3K | 602.4% |
| True Wealth Design, LLC | 130 | +58 | $5.7K | +$3.0K | 80.5% |
| SBI Securities Co., Ltd. | 47 | +45 | $2.1K | +$2.0K | 2250.0% |
| Parallel Advisors, LLC | 129 | +23 | $5.7K | +$1.7K | 21.7% |
| Parkside Financial Bank & Trust | 44 | +14 | $1.9K | +$821 | 46.7% |
| CWM, LLC | 9,584 | +9,193 | $422 | +$407 | 2351.2% |
| Handelsbanken Fonder AB | 23,500 | +2,500 | $1.0K | +$253 | 11.9% |
Reduced(105)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 1,774,168 | -1,239,277 | $78.2M | -$33.9M | -41.1% |
| Holocene Advisors, LP | 1,387,120 | -1,074,476 | $61.1M | -$30.6M | -43.6% |
| Vestal Point Capital, LP | 700,000 | -800,000 | $30.8M | -$25.0M | -53.3% |
| JANE STREET GROUP, LLC | 247,430 | -604,970 | $10.9M | -$20.8M | -71.0% |
| Balyasny Asset Management LLC | 16,647 | -542,056 | $733.3K | -$20.1M | -97.0% |
| MARSHALL WACE, LLP | 368,037 | -605,877 | $16.2M | -$20.1M | -62.2% |
| JPMORGAN CHASE & CO | 170,773 | -543,215 | $7.5M | -$19.1M | -76.1% |
| Caption Management, LLC | 260,000 | -529,402 | $11.5M | -$17.9M | -67.1% |
| Hudson Bay Capital Management LP | 100,000 | -460,800 | $4.4M | -$16.5M | -82.2% |
| Royal Bank of Canada | 4,346 | -403,445 | $191.0K | -$14.3M | -98.9% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,952,877 | -71,082 | $86.0M | +$10.7M | -3.5% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 32,827 | -226,963 | $1.4M | -$8.5M | -87.4% |
| Capital World Investors | 1,128,752 | 0 | $49.7M | +$7.7M | 0.0% |
| Russell Investments Group, Ltd. | 7,760 | -164,663 | $341.8K | -$6.1M | -95.5% |
| MORGAN STANLEY | 372,731 | -231,271 | $16.4M | -$6.1M | -38.3% |
| FEDERATED HERMES, INC. | 797,913 | -2,542 | $35.1M | +$5.3M | -0.3% |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 769,442 | 0 | $33.9M | +$5.2M | 0.0% |
| NORTHERN TRUST CORP | 721,062 | -17,633 | $31.8M | +$4.3M | -2.4% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 305,951 | -158,937 | $13.5M | -$3.8M | -34.2% |
| Fisher Asset Management, LLC | 531,439 | -1,737 | $23.4M | +$3.6M | -0.3% |
| LOOMIS SAYLES & CO L P | 691,913 | -32,325 | $30.5M | +$3.5M | -4.5% |
| Pictet Asset Management Holding SA | 1,195,967 | -126,964 | $52.7M | +$3.4M | -9.6% |
| VICTORY CAPITAL MANAGEMENT INC | 31,548 | -88,385 | $1.4M | -$3.1M | -73.7% |
| BARCLAYS PLC | 285,320 | -67,764 | $10.1M | -$3.0M | -19.2% |
| Artia Global Partners LP | 96,285 | -96,285 | $4.2M | -$2.9M | -50.0% |
| EVENTIDE ASSET MANAGEMENT, LLC | 2,431,333 | -368,123 | $107.1M | +$2.8M | -13.1% |
| Rock Springs Capital Management LP | 733,477 | -60,656 | $32.3M | +$2.7M | -7.6% |
| Eagle Health Investments LP | 363,300 | 0 | $16.0M | +$2.5M | 0.0% |
| UBS Group AG | 905,432 | -226,355 | $39.9M | -$2.3M | -20.0% |
| Candriam S.C.A. | 145,633 | -84,267 | $6.4M | -$2.1M | -36.6% |
| Lighthouse Investment Partners, LLC | 15,000 | -59,000 | $660.8K | -$2.1M | -79.7% |
| E. Ohman J:or Asset Management AB | 16,374 | -53,513 | $721.3K | -$1.9M | -76.6% |
| Bank of New York Mellon Corp | 232,018 | -9,609 | $10.2M | +$1.2M | -4.0% |
| PEREGRINE CAPITAL MANAGEMENT LLC | 152,854 | -2,047 | $6.7M | +$964.7K | -1.3% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 186,926 | -10,391 | $8.2M | +$822.1K | -5.3% |
| STATE OF WISCONSIN INVESTMENT BOARD | 38,200 | -28,153 | $1.7M | -$788.3K | -42.4% |
| TD Asset Management Inc | 281,444 | -30,954 | $12.4M | +$763.9K | -9.9% |
| UBS ASSET MANAGEMENT AMERICAS INC | 107,183 | -2,721 | $4.7M | +$628.6K | -2.5% |
| ALLIANCEBERNSTEIN L.P. | 82,110 | -32 | $3.6M | +$558.0K | -0.0% |
| Verition Fund Management LLC | 5,536 | -15,690 | $243.9K | -$546.6K | -73.9% |
| Aisling Capital Management LP | 77,031 | 0 | $3.4M | +$524.6K | 0.0% |
| Jasper Ridge Partners, L.P. | 42,455 | -21,714 | $1.9M | -$519.5K | -33.8% |
| Rafferty Asset Management, LLC | 129,132 | -12,277 | $5.7M | +$422.2K | -8.7% |
| AMERIPRISE FINANCIAL INC | 36,424 | -17,721 | $1.6M | -$411.6K | -32.7% |
| Legal & General Group Plc | 63,336 | -1,390 | $2.8M | +$379.6K | -2.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 60,815 | -1,560 | $2.7M | +$356.1K | -2.5% |
| Walleye Capital LLC | 5,500 | -10,100 | $242.3K | -$338.7K | -64.7% |
| MetLife Investment Management, LLC | 46,657 | -1,706 | $2.1M | +$254.2K | -3.5% |
| ENVESTNET ASSET MANAGEMENT INC | 12,480 | -8,131 | $549.7K | -$217.8K | -39.4% |
| RHUMBLINE ADVISERS | 108,864 | -14,899 | $4.8M | +$186.5K | -12.0% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,623 | 0 | $1.1M | +$174.5K | 0.0% |
| NEW YORK STATE COMMON RETIREMENT FUND | 25,286 | 0 | $1.1M | +$172.2K | 0.0% |
| PRUDENTIAL FINANCIAL INC | 5,030 | -5,290 | $221.6K | -$162.7K | -51.3% |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 9,235 | -5,898 | $406.8K | -$156.8K | -39.0% |
| Police & Firemen's Retirement System of New Jersey | 22,362 | -654 | $985.0K | +$127.9K | -2.8% |
| Erste Asset Management GmbH | 18,600 | 0 | $840.5K | +$127.0K | 0.0% |
| GOLDMAN SACHS GROUP INC | 1,324,213 | -238,876 | $58.3M | +$122.1K | -15.3% |
| Values First Advisors, Inc. | 18,564 | -588 | $817.8K | +$104.5K | -3.1% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 15,210 | 0 | $670.0K | +$103.6K | 0.0% |
| Arizona State Retirement System | 17,489 | -728 | $770.4K | +$92.0K | -4.0% |
| Clarius Group, LLC | 13,037 | 0 | $574.3K | +$88.8K | 0.0% |
| D. E. Shaw & Co., Inc. | 13,935 | -4,555 | $613.8K | -$74.7K | -24.6% |
| Spire Wealth Management | 9,455 | 0 | $416.5K | +$64.4K | 0.0% |
| EXCHANGE TRADED CONCEPTS, LLC | 19,451 | -4,919 | $856.8K | -$50.7K | -20.2% |
| Ameritas Investment Partners, Inc. | 6,783 | 0 | $298.8K | +$46.2K | 0.0% |
| Clearbridge Investments, LLC | 295,475 | -52,974 | $13.0M | +$39.4K | -15.2% |
| Moody Aldrich Partners LLC | 85,293 | -16,449 | $3.8M | -$31.7K | -16.2% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 6,402,437 | -480,621 | $282.0K | +$25.7K | -7.0% |
| PRINCIPAL FINANCIAL GROUP INC | 4,736 | -1,478 | $208.6K | -$22.8K | -23.8% |
| Steward Partners Investment Advisory, LLC | 351 | -425 | $15.5K | -$13.4K | -54.8% |
| GF FUND MANAGEMENT CO. LTD. | 2,004 | -64 | $88.3K | +$11.3K | -3.1% |
| SIGNATUREFD, LLC | 1,799 | -37 | $79.2K | +$10.9K | -2.0% |
| Accent Capital Management, LLC | 100 | -307 | $4.4K | -$10.8K | -75.4% |
| NBC SECURITIES, INC. | 3,499 | -392 | $154.1K | +$9.2K | -10.1% |
| Ramirez Asset Management, Inc. | 1,000 | 0 | $44.0K | +$6.8K | 0.0% |
| Optiver Holding B.V. | 382 | -200 | $16.8K | -$4.8K | -34.4% |
| Versant Capital Management, Inc | 128 | -126 | $5.6K | -$3.8K | -49.6% |
| JONES FINANCIAL COMPANIES LLLP | 630 | 0 | $27.8K | +$3.3K | 0.0% |
| SRS Capital Advisors, Inc. | 25 | -81 | $1.1K | -$2.8K | -76.4% |
| US BANCORP \DE\ | 2,324 | -498 | $102.4K | -$2.7K | -17.6% |
| Crews Bank & Trust | 300 | 0 | $13.2K | +$2.0K | 0.0% |
| Red Tortoise LLC | 256 | 0 | $11.3K | +$1.7K | 0.0% |
| PRIVATE TRUST CO NA | 238 | 0 | $10.5K | +$1.6K | 0.0% |
| WPG Advisers, LLC | 193 | 0 | $8.5K | +$1.3K | 0.0% |
| WHITTIER TRUST CO | 340 | 0 | $14.0K | +$1.3K | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 910 | -140 | $40.1K | +$984 | -13.3% |
| TD Waterhouse Canada Inc. | 100 | 0 | $4.4K | +$938 | 0.0% |
| DekaBank Deutsche Girozentrale | 38,000 | 0 | $638 | -$809 | 0.0% |
| GREAT WEST LIFE ASSURANCE CO /CAN/ | 6,868 | -12,699 | $303 | -$447 | -64.9% |
| Larson Financial Group LLC | 24 | -11 | $1.1K | -$246 | -31.4% |
| Fortitude Family Office, LLC | 30 | 0 | $1.3K | +$205 | 0.0% |
| Root Financial Partners, LLC | 20 | 0 | $881 | +$136 | 0.0% |
| CREATIVE FINANCIAL DESIGNS INC /ADV | 20 | 0 | $881 | +$136 | 0.0% |
| COMERICA BANK | 18 | 0 | $792 | +$122 | 0.0% |
| HUNTINGTON NATIONAL BANK | 15 | 0 | $661 | +$102 | 0.0% |
| FINANCIAL CONSULATE, INC | 10 | 0 | $441 | +$68 | 0.0% |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 5,738 | 0 | $253 | +$39 | 0.0% |
| Concord Wealth Partners | 5 | 0 | $220 | +$34 | 0.0% |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 25,243 | -5,479 | $1.1K | -$32 | -17.8% |
| BESSEMER GROUP INC | 2,322 | 0 | $102 | +$16 | 0.0% |
| AMALGAMATED BANK | 2,585 | -186 | $114 | +$11 | -6.7% |
| Penserra Capital Management LLC | 1,045 | -481 | $46 | -$10 | -31.5% |
| Daiwa Securities Group Inc. | 296 | 0 | $13 | +$2 | 0.0% |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | $0 | $0 | — |
| Covestor Ltd | 4 | 0 | $0 | $0 | 0.0% |
Sold Out(47)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| FMR LLC | 15,380,675 | $677.5M | +1,368,597 | 9.8% |
| Siren, L.L.C. | 10,825,013 | $476.8M | +1,575,008 | 17.0% |
| BlackRock, Inc. | 7,217,034 | $317.9M | +456,847 | 6.8% |
| Samsara BioCapital, LLC | 6,897,652 | $303.8M | +1,284,756 | 22.9% |
| WELLINGTON MANAGEMENT GROUP LLP | 5,759,428 | $253.7M | +1,213,541 | 26.7% |
| Redmile Group, LLC | 5,220,846 | $230.0M | +1,316,390 | 33.7% |
| VANGUARD GROUP INC | 5,195,465 | $228.9M | +280,538 | 5.7% |
| Bellevue Group AG | 4,056,592 | $178.7M | +812,055 | 25.0% |
| STATE STREET CORP | 4,034,434 | $177.7M | +271,331 | 7.2% |
| Orbis Allan Gray Ltd | 3,428,929 | $151.0M | +3,126,677 | 1034.5% |
| Paradigm Biocapital Advisors LP | 3,062,157 | $134.9M | +1,052,412 | 52.4% |
| JENNISON ASSOCIATES LLC | 2,795,188 | $123.1M | +1,188,676 | 74.0% |
| EVENTIDE ASSET MANAGEMENT, LLC | 2,431,333 | $107.1M | -368,123 | -13.1% |
| NORGES BANK | 2,079,515 | $91.6M | +349,411 | 20.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 2,034,024 | $89.6M | +79,214 | 4.0% |
| Hood River Capital Management LLC | 2,026,758 | $89.3M | +12,365 | 0.6% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,952,877 | $86.0M | -71,082 | -3.5% |
| JANUS HENDERSON GROUP PLC | 1,774,168 | $78.2M | -1,239,277 | -41.1% |
| Holocene Advisors, LP | 1,387,120 | $61.1M | -1,074,476 | -43.6% |
| GOLDMAN SACHS GROUP INC | 1,324,213 | $58.3M | -238,876 | -15.3% |
New & Closed Positions this quarter
Closed Positions
47 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for SRRK against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.