Institutional Manager · CIK 0001346824
RA CAPITAL MANAGEMENT, L.P.
Boston, MA · File #028-12884
Latest AUM
$9.76B
Positions
72
Top-10 Concentration
67.0%
Filings
14
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202572 pos · $9.76B
- 13F HOLDINGS REPORTQ/E Sep 202568 pos · $8.12B
- 13F HOLDINGS REPORTQ/E Jun 202564 pos · $5.94B
- 13F HOLDINGS REPORTQ/E Mar 202586 pos · $5.99B
- 13F HOLDINGS REPORTQ/E Dec 202490 pos · $7.51B
- 13F HOLDINGS REPORTQ/E Sep 202482 pos · $8.67B
- 13F HOLDINGS REPORTQ/E Jun 202479 pos · $7.56B
- 13F HOLDINGS REPORT (Amended)Q/E Mar 20241 pos · $61.3M
- 13F HOLDINGS REPORTQ/E Mar 202475 pos · $7.80B
- 13F HOLDINGS REPORT (Amended)Q/E Dec 20231 pos · $37.6M
- 13F HOLDINGS REPORTQ/E Dec 202365 pos · $5.04B
- 13F HOLDINGS REPORTQ/E Sep 202354 pos · $5.30B
- 13F HOLDINGS REPORTQ/E Jun 202359 pos · $4.42B
- 13F HOLDINGS REPORTQ/E Mar 202370 pos · $4.93B
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | ASCENDIS PHARMA A/S - ADR | ASND | 10,281,496 | $2.19B | 22.94% |
| 2 | CIDARA THERAPEUTICS INC | 171757206 | 3,365,523 | $743.4M | 7.78% |
| 3 | RHYTHM PHARMACEUTICALS INC | RYTM | 6,666,837 | $713.6M | 7.47% |
| 4 | AVIDITY BIOSCIENCES INC | 05370A108 | 8,641,031 | $623.3M | 6.52% |
| 5 | VAXCYTE INC | PCVX | 10,724,599 | $494.8M | 5.18% |
| 6 | SIONNA THERAPEUTICS INC | SION | 9,905,045 | $407.5M | 4.26% |
| 7 | NEWAMSTERDAM PHARMA CO NV | NAMSW | 9,550,191 | $335.0M | 3.51% |
| 8 | TYRA BIOSCIENCES INC | TYRA | 12,198,625 | $320.7M | 3.36% |
| 9 | WAVE LIFE SCIENCES LTD | WVE | 18,203,009 | $309.5M | 3.24% |
| 10 | MINERALYS THERAPEUTICS INC | MLYS | 7,323,750 | $265.8M | 2.78% |
| 11 | EDGEWISE THERAPEUTICS INC | EWTX | 10,428,437 | $258.8M | 2.71% |
| 12 | SEPTERNA INC | SEPN | 6,995,858 | $195.0M | 2.04% |
| 13 | NUVALENT INC-A | NUVL | 1,880,057 | $189.1M | 1.98% |
| 14 | DISC MEDICINE INC | IRON | 1,976,132 | $156.9M | 1.64% |
| 15 | JANUX THERAPEUTICS INC | JANX | 11,189,693 | $154.4M | 1.62% |
| 16 | PEPGEN INC | PEPG | 20,064,545 | $130.6M | 1.37% |
| 17 | TAYSHA GENE THERAPIES INC | TSHA | 23,555,648 | $129.6M | 1.36% |
| 18 | ARS PHARMACEUTICALS INC | SPRY | 10,860,977 | $126.5M | 1.32% |
| 19 | BIOCRYST PHARMACEUTICALS INC | BCRX | 15,827,186 | $123.5M | 1.29% |
| 20 | BICARA THERAPEUTICS INC | BCAX | 6,955,993 | $117.1M | 1.23% |