Institutional Manager · CIK 0001534261
Casdin Capital, LLC
New York, NY · File #028-17113
Latest AUM
$1.61B
Positions
38
Top-10 Concentration
79.5%
Filings
13
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202538 pos · $1.61B
- 13F HOLDINGS REPORTQ/E Sep 202532 pos · $1.20B
- 13F HOLDINGS REPORTQ/E Jun 202533 pos · $1.10B
- 13F HOLDINGS REPORTQ/E Mar 202544 pos · $1.22B
- 13F HOLDINGS REPORTQ/E Dec 202439 pos · $1.50B
- 13F HOLDINGS REPORTQ/E Sep 202435 pos · $1.50B
- 13F HOLDINGS REPORT (Amended)Q/E Sep 202438 pos · $1.31B
- 13F HOLDINGS REPORTQ/E Jun 202438 pos · $1.30B
- 13F HOLDINGS REPORTQ/E Mar 202437 pos · $1.35B
- 13F HOLDINGS REPORTQ/E Dec 202340 pos · $903.5M
- 13F HOLDINGS REPORTQ/E Sep 202341 pos · $1.14B
- 13F HOLDINGS REPORTQ/E Jun 202341 pos · $1.21B
- 13F HOLDINGS REPORTQ/E Mar 202346 pos · $1.29B
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | GENEDX HOLDINGS CORP | WGSWW | 3,007,164 | $391.1M | 24.29% |
| 2 | REVOLUTION MEDICINES INC | RVMDW | 2,577,333 | $205.3M | 12.75% |
| 3 | BIOLIFE SOLUTIONS INC | BLFS | 5,957,165 | $144.0M | 8.95% |
| 4 | STANDARD BIOTOOLS INC | LAB | 88,783,856 | $113.6M | 7.06% |
| 5 | RELAY THERAPEUTICS INC | RLAY | 13,003,574 | $110.0M | 6.83% |
| 6 | STRUCTURE THERAPEUTICS INC | GPCR | 1,175,000 | $81.7M | 5.08% |
| 7 | ILLUMINA INC | ILMN | 600,000 | $78.7M | 4.89% |
| 8 | AVIDITY BIOSCIENCES INC | 05370A108 | 1,000,000 | $72.1M | 4.48% |
| 9 | BEAM THERAPEUTICS INC | BEAM | 1,600,000 | $44.4M | 2.75% |
| 10 | GUARDANT HEALTH INC | GH | 380,000 | $38.8M | 2.41% |
| 11 | MAZE THERAPEUTICS INC | MAZE | 758,857 | $31.4M | 1.95% |
| 12 | DENALI THERAPEUTICS INC | DNLI | 1,840,000 | $30.4M | 1.89% |
| 13 | ALNYLAM PHARMACEUTICALS INC | ALNY | 75,000 | $29.8M | 1.85% |
| 14 | NEUROGENE INC | NGNE | 1,295,361 | $26.7M | 1.66% |
| 15 | 10X GENOMICS INC | TXG | 1,400,000 | $22.8M | 1.42% |
| 16 | ARS PHARMACEUTICALS INC | SPRY | 1,600,000 | $18.6M | 1.16% |
| 17 | TEMPUS AI INC | TEM | 294,127 | $17.4M | 1.08% |
| 18 | UNITEDHEALTH GROUP INC | UNH | 50,000 | $16.5M | 1.03% |
| 19 | SEPTERNA INC | SEPN | 553,268 | $15.4M | 0.96% |
| 20 | HIMS & HERS HEALTH INC | HIMS | 385,000 | $12.5M | 0.78% |