New Positions
32 managers initiated
Top five by reported value
Urogen Pharma Ltd NASDAQ NMS - GLOBAL MARKET:URGN
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
32 new52 added84 reduced25 exited
Total Institutional Holders
167
as of 2025-12-31
Top Holder
RTW INVESTMENTS, LP
$106.4M
Largest QoQ Increase
AMERICAN CENTURY COMPANIES INC
+1,358,812 sh
Largest QoQ Decrease
TORONTO DOMINION BANK
-3,190,510 sh
New Positions(32)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| AMERICAN CENTURY COMPANIES INC | 1,358,812 | +1,358,812 | $31.8M | +$31.8M | — |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1,125,100 | +1,125,100 | $26.3M | +$26.3M | — |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 781,620 | +781,620 | $18.3M | +$18.3M | — |
| J. Goldman & Co LP | 597,303 | +597,303 | $14.0M | +$14.0M | — |
| Opaleye Management Inc. | 268,423 | +268,423 | $6.3M | +$6.3M | — |
| EAM Investors, LLC | 160,412 | +160,412 | $3.8M | +$3.8M | — |
| Aisling Capital Management LP | 108,000 | +108,000 | $2.5M | +$2.5M | — |
| Elmind Capital, LP | 100,000 | +100,000 | $2.3M | +$2.3M | — |
| Focus Partners Wealth | 35,277 | +35,277 | $826.2K | +$826.2K | — |
| DARK FOREST CAPITAL MANAGEMENT LP | 31,516 | +31,516 | $738.1K | +$738.1K | — |
| Susquehanna Portfolio Strategies, LLC | 27,380 | +27,380 | $641.2K | +$641.2K | — |
| Toroso Investments, LLC | 26,972 | +26,972 | $631.7K | +$631.7K | — |
| MML INVESTORS SERVICES, LLC | 24,363 | +24,363 | $570.6K | +$570.6K | — |
| Squarepoint Ops LLC | 22,831 | +22,831 | $534.7K | +$534.7K | — |
| SIMPLEX TRADING, LLC | 22,109 | +22,109 | $517.8K | +$517.8K | — |
| Cinctive Capital Management LP | 16,991 | +16,991 | $397.9K | +$397.9K | — |
| OPPENHEIMER & CO INC | 16,962 | +16,962 | $397.3K | +$397.3K | — |
| DNB Asset Management AS | 16,961 | +16,961 | $397.2K | +$397.2K | — |
| FRANKLIN RESOURCES INC | 16,745 | +16,745 | $392.2K | +$392.2K | — |
| WINTON GROUP Ltd | 13,188 | +13,188 | $308.9K | +$308.9K | — |
| ProShare Advisors LLC | 8,812 | +8,812 | $206.4K | +$206.4K | — |
| Pinnacle Wealth Planning Services, Inc. | 688 | +688 | $16.1K | +$16.1K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 403 | +403 | $9.4K | +$9.4K | — |
| Sound Income Strategies, LLC | 488 | +488 | $9.2K | +$9.2K | — |
| Aster Capital Management (DIFC) Ltd | 298 | +298 | $7.0K | +$7.0K | — |
| Quantbot Technologies LP | 200 | +200 | $4.7K | +$4.7K | — |
| Rockefeller Capital Management L.P. | 112 | +112 | $2.6K | +$2.6K | — |
| ALGERT GLOBAL LLC | 65,935 | +65,935 | $1.5K | +$1.5K | — |
| IFP Advisors, Inc | 65 | +65 | $1.4K | +$1.4K | — |
| Allworth Financial LP | 35 | +35 | $820 | +$820 | — |
| US BANCORP \DE\ | 17 | +17 | $398 | +$398 | — |
| MAI Capital Management | 2 | +2 | $47 | +$47 | — |
Added To(52)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 4,473,648 | +257,564 | $104.8M | +$20.7M | 6.1% |
| Boxer Capital Management, LLC | 1,650,000 | +1,075,000 | $31.1M | +$19.6M | 186.9% |
| BIOIMPACT CAPITAL LLC | 941,378 | +806,378 | $22.0M | +$19.4M | 597.3% |
| SUPERSTRING CAPITAL MANAGEMENT LP | 718,354 | +630,442 | $16.8M | +$15.1M | 717.1% |
| MORGAN STANLEY | 2,562,901 | +34,455 | $60.0M | +$9.6M | 1.4% |
| BlackRock, Inc. | 2,601,009 | +19,723 | $60.9M | +$9.4M | 0.8% |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1,738,821 | +161,538 | $40.7M | +$9.3M | 10.2% |
| ACORN CAPITAL ADVISORS, LLC | 1,448,420 | +188,671 | $33.9M | +$8.8M | 15.0% |
| ORBIMED ADVISORS LLC | 875,487 | +186,487 | $20.5M | +$6.8M | 27.1% |
| Woodline Partners LP | 500,726 | +194,355 | $11.7M | +$5.6M | 63.4% |
| DEUTSCHE BANK AG\ | 366,680 | +204,421 | $8.6M | +$5.4M | 126.0% |
| D. E. Shaw & Co., Inc. | 962,624 | +73,691 | $22.5M | +$4.8M | 8.3% |
| VANGUARD GROUP INC | 439,751 | +135,966 | $10.3M | +$4.2M | 44.8% |
| CITADEL ADVISORS LLC | 822,157 | +37,780 | $19.3M | +$3.6M | 4.8% |
| AMERIPRISE FINANCIAL INC | 136,019 | +105,535 | $3.2M | +$2.6M | 346.2% |
| Hennion & Walsh Asset Management, Inc. | 161,924 | +96,741 | $3.8M | +$2.5M | 148.4% |
| ADAR1 Capital Management, LLC | 165,375 | +90,375 | $3.9M | +$2.4M | 120.5% |
| GOLDMAN SACHS GROUP INC | 459,722 | +34,806 | $10.8M | +$2.3M | 8.2% |
| UBS Group AG | 235,040 | +54,580 | $5.5M | +$1.9M | 30.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 475,212 | +3,983 | $11.1M | +$1.7M | 0.8% |
| FMR LLC | 123,563 | +50,447 | $2.9M | +$1.4M | 69.0% |
| RICE HALL JAMES & ASSOCIATES, LLC | 281,876 | +22,733 | $6.6M | +$1.4M | 8.8% |
| Privium Fund Management B.V. | 214,622 | +18,000 | $5.0M | +$1.1M | 9.2% |
| Russell Investments Group, Ltd. | 47,257 | +43,936 | $1.1M | +$1.0M | 1323.0% |
| TD Asset Management Inc | 80,188 | +36,188 | $1.9M | +$1.0M | 82.2% |
| BANK OF AMERICA CORP /DE/ | 128,630 | +20,176 | $3.0M | +$848.9K | 18.6% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 55,686 | +19,749 | $1.3M | +$576.1K | 55.0% |
| ExodusPoint Capital Management, LP | 35,393 | +18,850 | $828.9K | +$498.9K | 113.9% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 39,383 | +18,007 | $922.4K | +$495.9K | 84.2% |
| WELLINGTON MANAGEMENT GROUP LLP | 126,034 | +736 | $3.0M | +$452.0K | 0.6% |
| Bank of New York Mellon Corp | 98,829 | +3,476 | $2.3M | +$412.3K | 3.6% |
| FARALLON CAPITAL MANAGEMENT LLC | 22,000 | +11,000 | $477.1K | +$257.6K | 100.0% |
| NEOS Investment Management LLC | 53,576 | +3,118 | $1.3M | +$248.1K | 6.2% |
| INTECH INVESTMENT MANAGEMENT LLC | 22,210 | +6,983 | $520.2K | +$216.4K | 45.9% |
| MEITAV DASH INVESTMENTS LTD | 35,517 | +4,004 | $831.7K | +$203.1K | 12.7% |
| Invesco Ltd. | 27,066 | +4,711 | $633.9K | +$187.9K | 21.1% |
| BARCLAYS PLC | 70,154 | +14,535 | $961.1K | -$148.5K | 26.1% |
| Quantinno Capital Management LP | 23,514 | +3,205 | $550.7K | +$145.5K | 15.8% |
| NEW YORK STATE COMMON RETIREMENT FUND | 12,737 | +4,900 | $298.3K | +$142.0K | 62.5% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 17,154 | +137 | $401.7K | +$62.3K | 0.8% |
| Creative Planning | 10,576 | +132 | $247.7K | +$39.3K | 1.3% |
| Mirae Asset Global Investments Co., Ltd. | 2,275 | +486 | $53.3K | +$17.6K | 27.2% |
| SG Americas Securities, LLC | 1,377,647 | +220,264 | $32.3K | +$9.2K | 19.0% |
| Tower Research Capital LLC (TRC) | 1,469 | +179 | $34.4K | +$8.7K | 13.9% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 616,606 | +259,991 | $14.4K | +$7.3K | 72.9% |
| Farther Finance Advisors, LLC | 256 | +211 | $6.0K | +$5.1K | 468.9% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 31,569 | +412 | $626.6K | +$5.1K | 1.3% |
| CIBC Private Wealth Group, LLC | 575 | +66 | $13.5K | +$3.3K | 13.0% |
| Sterling Capital Management LLC | 584 | +60 | $13.7K | +$3.2K | 11.4% |
| FEDERATED HERMES, INC. | 196 | +64 | $4.6K | +$2.0K | 48.5% |
| PNC Financial Services Group, Inc. | 63 | +34 | $1.5K | +$896 | 117.2% |
| ROTHSCHILD INVESTMENT LLC | 50 | +5 | $1.2K | +$273 | 11.1% |
Reduced(84)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 4,543,895 | 0 | $106.4M | +$15.8M | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 618,952 | -894,785 | $14.5M | -$15.7M | -59.1% |
| TANG CAPITAL MANAGEMENT LLC | 350,000 | -650,000 | $8.2M | -$11.8M | -65.0% |
| Soleus Capital Management, L.P. | 150,000 | -529,000 | $3.5M | -$10.0M | -77.9% |
| Jefferies Financial Group Inc. | 2,199,652 | 0 | $51.5M | +$7.6M | 0.0% |
| JANE STREET GROUP, LLC | 78,500 | -389,319 | $1.8M | -$7.5M | -83.2% |
| JPMORGAN CHASE & CO | 146,271 | -388,274 | $3.4M | -$7.2M | -72.6% |
| BNP PARIBAS ARBITRAGE, SNC | 9,246 | -299,082 | $216.5K | -$5.9M | -97.0% |
| Parkman Healthcare Partners LLC | 168,768 | -233,827 | $4.0M | -$4.1M | -58.1% |
| MENORA MIVTACHIM HOLDINGS LTD. | 1,152,531 | 0 | $27.0M | +$4.0M | 0.0% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 435,490 | -251,985 | $10.2M | -$3.5M | -36.6% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 450,625 | -237,500 | $10.6M | -$3.2M | -34.5% |
| Nuveen, LLC | 302,601 | -204,930 | $7.1M | -$3.0M | -40.4% |
| STATE STREET CORP | 807,421 | -12,025 | $18.9M | +$2.6M | -1.5% |
| TCG Crossover Management, LLC | 717,347 | 0 | $16.8M | +$2.5M | 0.0% |
| Caption Management, LLC | 1,000,000 | -70,000 | $23.4M | +$2.1M | -6.5% |
| TWO SIGMA INVESTMENTS, LP | 241,213 | -144,990 | $5.6M | -$2.1M | -37.5% |
| PANAGORA ASSET MANAGEMENT INC | 74,055 | -110,327 | $1.7M | -$1.9M | -59.8% |
| Jump Financial, LLC | 17,900 | -85,966 | $419.2K | -$1.7M | -82.8% |
| DIADEMA PARTNERS LP | 21,810 | -68,190 | $510.8K | -$1.3M | -75.8% |
| Royal Bank of Canada | 8,391 | -88,150 | $196.0K | -$1.1M | -91.3% |
| WELLS FARGO & COMPANY/MN | 84,158 | -41,811 | $2.0M | -$542.1K | -33.2% |
| AQR CAPITAL MANAGEMENT LLC | 153,413 | -50,778 | $3.6M | -$480.7K | -24.9% |
| NORTHERN TRUST CORP | 237,457 | -23,944 | $5.6M | +$346.3K | -9.2% |
| Atom Investors LP | 234,423 | -57,539 | $5.5M | -$334.5K | -19.7% |
| ARK Investment Management LLC | 121,484 | -5,236 | $2.8M | +$317.1K | -4.1% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 90,989 | -70 | $2.1M | +$314.3K | -0.1% |
| TRUIST FINANCIAL CORP | 72,286 | 0 | $1.7M | +$250.8K | 0.0% |
| OAK RIDGE INVESTMENTS LLC | 85,230 | -2,277 | $2.0M | +$250.3K | -2.6% |
| SRS Capital Advisors, Inc. | 14 | -12,365 | $328 | -$246.6K | -99.9% |
| RENAISSANCE TECHNOLOGIES LLC | 244,300 | -30,800 | $5.7M | +$233.3K | -11.2% |
| ADVISOR GROUP HOLDINGS, INC. | 2,915 | -11,975 | $68.3K | -$218.3K | -80.4% |
| Main Street Financial Solutions, LLC | 20,990 | -11,200 | $491.6K | -$150.6K | -34.8% |
| Voya Investment Management LLC | 76,762 | -6,849 | $1.8M | +$129.7K | -8.2% |
| Coastal Bridge Advisors, LLC | 37,000 | 0 | $866.5K | +$128.4K | 0.0% |
| ALLIANCEBERNSTEIN L.P. | 35,040 | 0 | $820.6K | +$121.6K | 0.0% |
| Persistent Asset Partners Ltd | 12,806 | -7,920 | $299.9K | -$113.6K | -38.2% |
| Palo Alto Investors LP | 24,500 | 0 | $573.8K | +$85.0K | 0.0% |
| Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD | 21,823 | 0 | $511.1K | +$76.9K | 0.0% |
| Allianz Asset Management GmbH | 22,000 | 0 | $515.2K | +$76.3K | 0.0% |
| Cresset Asset Management, LLC | 11,216 | -5,545 | $262.7K | -$71.7K | -33.1% |
| MetLife Investment Management, LLC | 22,445 | -321 | $525.7K | +$71.5K | -1.4% |
| Cetera Investment Advisers | 30,096 | -2,000 | $704.8K | +$64.5K | -6.2% |
| XTX Topco Ltd | 22,491 | -6,811 | $526.7K | -$57.8K | -23.2% |
| RHUMBLINE ADVISERS | 45,760 | -5,193 | $1.1M | +$55.2K | -10.2% |
| Vivaldi Capital Management LP | 15,661 | 0 | $366.8K | +$54.3K | 0.0% |
| PARTNERS CAPITAL INVESTMENT GROUP, LLP | 15,384 | 0 | $360.3K | +$53.4K | 0.0% |
| Police & Firemen's Retirement System of New Jersey | 10,469 | 0 | $245.2K | +$36.3K | 0.0% |
| HighVista Strategies LLC | 28,005 | -3,881 | $655.9K | +$19.8K | -12.2% |
| China Universal Asset Management Co., Ltd. | 7,627 | -482 | $178.6K | +$16.8K | -5.9% |
| CITIGROUP INC | 3,402 | -1,291 | $79.7K | -$14.0K | -27.5% |
| STRS OHIO | 3,800 | 0 | $89.0K | +$13.2K | 0.0% |
| Annandale Capital, LLC | 60,552 | -10,000 | $1.4K | -$12.7K | -14.2% |
| Ameritas Investment Partners, Inc. | 3,082 | 0 | $72.2K | +$10.7K | 0.0% |
| MARSHALL WACE, LLP | 16,300 | -2,375 | $381.7K | +$9.2K | -12.7% |
| Brinker Capital Investments, LLC | 9,008 | -2,000 | $211.0K | -$8.6K | -18.2% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,272 | -26 | $53.2K | +$7.4K | -1.1% |
| Legal & General Group Plc | 3,643 | -301 | $85.3K | +$6.6K | -7.6% |
| JONES FINANCIAL COMPANIES LLLP | 1,000 | 0 | $23.4K | +$5.1K | 0.0% |
| Rossby Financial, LCC | 770 | 0 | $18.0K | +$4.3K | 0.0% |
| Activest Wealth Management | 1,001 | 0 | $23.4K | +$3.5K | 0.0% |
| Newbridge Financial Services Group, Inc. | 1,000 | 0 | $23.4K | +$3.5K | 0.0% |
| Migdal Insurance & Financial Holdings Ltd. | 770,909 | 0 | $18.1K | +$2.7K | 0.0% |
| QUADRANT CAPITAL GROUP LLC | 688 | 0 | $16.1K | +$2.4K | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 464 | -188 | $10.9K | -$2.1K | -28.8% |
| EverSource Wealth Advisors, LLC | 584 | -5 | $13.7K | +$1.9K | -0.8% |
| GF FUND MANAGEMENT CO. LTD. | 919 | -76 | $21.5K | +$1.7K | -7.6% |
| GAMMA Investing LLC | 352 | -22 | $8.2K | +$783 | -5.9% |
| Costello Asset Management, INC | 200 | 0 | $4.7K | +$694 | 0.0% |
| SBI Securities Co., Ltd. | 18 | -29 | $422 | -$516 | -61.7% |
| Larson Financial Group LLC | 140 | 0 | $3.3K | +$486 | 0.0% |
| Optiver Holding B.V. | 223 | -59 | $5.2K | -$403 | -20.9% |
| HRT FINANCIAL LP | 130,899 | -2,775 | $3.1K | +$399 | -2.1% |
| NewEdge Advisors, LLC | 100 | 0 | $2.3K | +$347 | 0.0% |
| Smartleaf Asset Management LLC | 72 | 0 | $1.7K | +$290 | 0.0% |
| Parkside Financial Bank & Trust | 45 | 0 | $1.1K | +$156 | 0.0% |
| DecisionPoint Financial, LLC | 22 | 0 | $516 | +$124 | 0.0% |
| True Wealth Design, LLC | 16 | 0 | $375 | +$55 | 0.0% |
| SHIKIAR ASSET MANAGEMENT INC | 10,750 | 0 | $252 | +$38 | 0.0% |
| SIGNATUREFD, LLC | 10 | 0 | $234 | +$34 | 0.0% |
| CWM, LLC | 3,889 | -382 | $91 | +$6 | -8.9% |
| Daiwa Securities Group Inc. | 160 | 0 | $4 | +$1 | 0.0% |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | $0 | $0 | — |
| AMALGAMATED BANK | 1,159 | -176 | $27 | $0 | -13.2% |
Sold Out(25)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | 4,543,895 | $106.4M | 0 | 0.0% |
| Paradigm Biocapital Advisors LP | 4,473,648 | $104.8M | +257,564 | 6.1% |
| BlackRock, Inc. | 2,601,009 | $60.9M | +19,723 | 0.8% |
| MORGAN STANLEY | 2,562,901 | $60.0M | +34,455 | 1.4% |
| Jefferies Financial Group Inc. | 2,199,652 | $51.5M | 0 | 0.0% |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1,738,821 | $40.7M | +161,538 | 10.2% |
| ACORN CAPITAL ADVISORS, LLC | 1,448,420 | $33.9M | +188,671 | 15.0% |
| AMERICAN CENTURY COMPANIES INC | 1,358,812 | $31.8M | +1,358,812 | — |
| Boxer Capital Management, LLC | 1,650,000 | $31.1M | +1,075,000 | 186.9% |
| MENORA MIVTACHIM HOLDINGS LTD. | 1,152,531 | $27.0M | 0 | 0.0% |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1,125,100 | $26.3M | +1,125,100 | — |
| Caption Management, LLC | 1,000,000 | $23.4M | -70,000 | -6.5% |
| D. E. Shaw & Co., Inc. | 962,624 | $22.5M | +73,691 | 8.3% |
| BIOIMPACT CAPITAL LLC | 941,378 | $22.0M | +806,378 | 597.3% |
| ORBIMED ADVISORS LLC | 875,487 | $20.5M | +186,487 | 27.1% |
| CITADEL ADVISORS LLC | 822,157 | $19.3M | +37,780 | 4.8% |
| STATE STREET CORP | 807,421 | $18.9M | -12,025 | -1.5% |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 781,620 | $18.3M | +781,620 | — |
| SUPERSTRING CAPITAL MANAGEMENT LP | 718,354 | $16.8M | +630,442 | 717.1% |
| TCG Crossover Management, LLC | 717,347 | $16.8M | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
25 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for URGN against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.