Institutional Manager · CIK 0001389933
DAFNA Capital Management LLC
LOS ANGELES, CA · File #028-12327
Latest AUM
$430.5M
Positions
77
Top-10 Concentration
58.1%
Filings
12
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202577 pos · $430.5M
- 13F HOLDINGS REPORTQ/E Sep 202575 pos · $404.8M
- 13F HOLDINGS REPORTQ/E Jun 202576 pos · $362.3M
- 13F HOLDINGS REPORTQ/E Mar 202583 pos · $352.7M
- 13F HOLDINGS REPORTQ/E Dec 202482 pos · $393.4M
- 13F HOLDINGS REPORTQ/E Sep 202484 pos · $423.3M
- 13F HOLDINGS REPORTQ/E Jun 202483 pos · $418.6M
- 13F HOLDINGS REPORTQ/E Mar 202472 pos · $439.3M
- 13F HOLDINGS REPORTQ/E Dec 202375 pos · $321.5M
- 13F HOLDINGS REPORTQ/E Sep 202373 pos · $365.7M
- 13F HOLDINGS REPORTQ/E Jun 202372 pos · $333.5M
- 13F HOLDINGS REPORTQ/E Mar 202379 pos · $355.1M
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | REVOLUTION MEDICINES INC | RVMDW | 604,514 | $48.1M | 11.84% |
| 2 | SPDR S&P BIOTECH ETF | 78464A870 | 336,505 | $41.0M | 10.09% |
| 3 | STEREOTAXIS INC | STXS | 13,680,554 | $31.5M | 7.74% |
| 4 | ATRICURE INC | ATRC | 597,431 | $23.6M | 5.81% |
| 5 | CYTOKINETICS INC | CYTK | 370,997 | $23.6M | 5.80% |
| 6 | IDEAYA BIOSCIENCES INC | IDYA | 506,740 | $17.5M | 4.31% |
| 7 | AXOGEN INC | AXGN | 476,826 | $15.6M | 3.84% |
| 8 | XENON PHARMACEUTICALS INC | XENE | 287,939 | $12.9M | 3.17% |
| 9 | ISHARES NASDAQ BIOTECH INDX | 464287556 | 68,095 | $11.5M | 2.83% |
| 10 | BIOHAVEN LTD | BHVN | 955,235 | $10.8M | 2.65% |
| 11 | ARCUS BIOSCIENCES INC | RCUS | 431,329 | $10.3M | 2.53% |
| 12 | NEUROCRINE BIOSCIENCES INC | NBIX | 70,615 | $10.0M | 2.46% |
| 13 | DAY ONE BIOPHARMACEUTICALS I | DAWN | 999,163 | $9.3M | 2.29% |
| 14 | TANDEM DIABETES CARE INC | TNDM | 355,208 | $7.8M | 1.92% |
| 15 | ASCENDIS PHARMA A/S | ASND | 28,177 | $6.0M | 1.48% |
| 16 | DEXCOM INC | DXCM | 88,279 | $5.9M | 1.44% |
| 17 | SYNDAX PHARMACEUTICALS INC | SNDX | 277,855 | $5.8M | 1.44% |
| 18 | KALVISTA PHARMACEUTICALS INC | KALV | 356,802 | $5.8M | 1.42% |
| 19 | COMPASS PATHWAYS PLC | CMPS | 811,046 | $5.6M | 1.38% |
| 20 | INOGEN INC | INGN | 827,071 | $5.6M | 1.37% |