New Positions
59 managers initiated
Top five by reported value
Ultragenyx Pharmaceutical Inc NASDAQ NMS - GLOBAL MARKET:RARE
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
59 new120 added114 reduced68 exited
Total Institutional Holders
292
as of 2025-12-31
Top Holder
VANGUARD GROUP INC
$236.1M
Largest QoQ Increase
CITADEL ADVISORS LLC
+2,070,172 sh
Largest QoQ Decrease
FMR LLC
-4,617,047 sh
New Positions(59)
Added To(120)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 10,263,815 | +131,087 | $236.1M | -$68.7M | 1.3% |
| CITADEL ADVISORS LLC | 2,661,725 | +2,070,172 | $61.2M | +$43.4M | 349.9% |
| BlackRock, Inc. | 6,631,554 | +206,291 | $152.5M | -$40.7M | 3.2% |
| NORGES BANK | 1,261,026 | +320,400 | $29.0M | -$23.2M | 34.1% |
| MILLENNIUM MANAGEMENT LLC | 880,644 | +781,431 | $20.3M | +$17.3M | 787.6% |
| MORGAN STANLEY | 1,826,295 | +916,112 | $42.0M | +$14.6M | 100.7% |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 1,965,084 | +895,986 | $45.2M | +$13.0M | 83.8% |
| STATE STREET CORP | 4,303,046 | +610,559 | $99.0M | -$12.1M | 16.5% |
| JANE STREET GROUP, LLC | 1,181,899 | +589,031 | $27.2M | +$9.4M | 99.3% |
| Ikarian Capital, LLC | 517,771 | +425,171 | $11.9M | +$9.1M | 459.1% |
| AQR CAPITAL MANAGEMENT LLC | 1,360,497 | +614,315 | $31.3M | +$8.8M | 82.3% |
| Rock Springs Capital Management LP | 1,267,241 | +20,900 | $29.1M | -$8.3M | 1.7% |
| BANK OF AMERICA CORP /DE/ | 1,213,928 | +558,907 | $27.9M | +$8.2M | 85.3% |
| RENAISSANCE TECHNOLOGIES LLC | 366,100 | +344,200 | $8.4M | +$7.8M | 1571.7% |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 348,350 | +327,502 | $8.0M | +$7.4M | 1570.9% |
| Balyasny Asset Management LLC | 702,154 | +392,154 | $16.1M | +$6.8M | 126.5% |
| Russell Investments Group, Ltd. | 840,820 | +369 | $19.3M | -$5.9M | 0.0% |
| Verition Fund Management LLC | 282,376 | +258,856 | $6.5M | +$5.8M | 1100.6% |
| MOORE CAPITAL MANAGEMENT, LP | 603,300 | +333,300 | $13.9M | +$5.8M | 123.4% |
| Caption Management, LLC | 873,800 | +21,999 | $20.1M | -$5.5M | 2.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,838,208 | +257,701 | $42.3M | -$5.3M | 16.3% |
| Squarepoint Ops LLC | 390,599 | +256,827 | $9.0M | +$5.0M | 192.0% |
| abrdn plc | 1,469,951 | +496,295 | $33.8M | +$4.5M | 51.0% |
| SPHERA FUNDS MANAGEMENT LTD. | 650,623 | +298,065 | $15.0M | +$4.4M | 84.5% |
| Candriam S.C.A. | 799,384 | +44,670 | $18.4M | -$4.3M | 5.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,280,716 | +442,590 | $29.5M | +$4.2M | 52.8% |
| Connor, Clark & Lunn Investment Management Ltd. | 263,869 | +184,947 | $6.1M | +$3.7M | 234.3% |
| BNP PARIBAS ARBITRAGE, SNC | 903,050 | +330,031 | $20.8M | +$3.5M | 57.6% |
| Royal Bank of Canada | 163,227 | +147,394 | $3.8M | +$3.2M | 930.9% |
| NORTHERN TRUST CORP | 526,686 | +27,454 | $12.1M | -$2.9M | 5.5% |
| Legal & General Group Plc | 411,273 | +8,458 | $9.5M | -$2.7M | 2.1% |
| LMR Partners LLP | 115,474 | +105,074 | $2.7M | +$2.3M | 1010.3% |
| XTX Topco Ltd | 119,996 | +105,622 | $2.8M | +$2.3M | 734.8% |
| AMERIPRISE FINANCIAL INC | 276,927 | +138,243 | $6.4M | +$2.2M | 99.7% |
| Nuveen, LLC | 801,473 | +119,329 | $18.4M | -$2.1M | 17.5% |
| 683 Capital Management, LLC | 222,395 | +116,395 | $5.1M | +$1.9M | 109.8% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,461,910 | +516,781 | $56.6M | -$1.9M | 26.6% |
| Stonepine Capital Management, LLC | 100,000 | +80,000 | $2.3M | +$1.7M | 400.0% |
| BOOTHBAY FUND MANAGEMENT, LLC | 176,200 | +96,931 | $4.1M | +$1.7M | 122.3% |
| Man Group plc | 78,371 | +71,219 | $1.8M | +$1.6M | 995.8% |
| Rafferty Asset Management, LLC | 157,061 | +577 | $3.6M | -$1.1M | 0.4% |
| UBS Group AG | 668,811 | +121,786 | $15.4M | -$1.1M | 22.3% |
| Swiss National Bank | 171,052 | +6,100 | $3.9M | -$1.0M | 3.7% |
| Jump Financial, LLC | 115,928 | +58,460 | $2.7M | +$937.7K | 101.7% |
| Trexquant Investment LP | 165,017 | +9,629 | $3.8M | -$878.7K | 6.2% |
| Entropy Technologies, LP | 60,641 | +40,577 | $1.4M | +$791.2K | 202.2% |
| D. E. Shaw & Co., Inc. | 344,763 | +107,123 | $7.9M | +$781.3K | 45.1% |
| Engineers Gate Manager LP | 76,702 | +43,579 | $1.8M | +$767.8K | 131.6% |
| Birchview Capital, LP | 62,000 | +40,000 | $1.4M | +$764.2K | 181.8% |
| WELLS FARGO & COMPANY/MN | 63,563 | +38,615 | $1.5M | +$711.5K | 154.8% |
| PDT Partners, LLC | 176,813 | +20,120 | $4.1M | -$646.6K | 12.8% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 175,635 | +25,064 | $4.0M | -$570.4K | 16.6% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 96,836 | +4,070 | $2.2M | -$563.2K | 4.4% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 83,337 | +2,447 | $1.9M | -$516.4K | 3.0% |
| Palo Alto Investors LP | 461,294 | +91,763 | $10.6M | -$505.7K | 24.8% |
| Privium Fund Management B.V. | 357,502 | +67,698 | $8.2M | -$494.8K | 23.4% |
| Fisher Asset Management, LLC | 198,696 | +30,612 | $4.6M | -$486.0K | 18.2% |
| Ensign Peak Advisors, Inc | 250,571 | +73,150 | $5.8M | +$426.3K | 41.2% |
| Brevan Howard Capital Management LP | 107,903 | +40,868 | $2.4M | +$403.3K | 61.0% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 66,175 | +3,572 | $1.5M | -$365.3K | 5.7% |
| PROFUND ADVISORS LLC | 56,624 | +24,360 | $1.3M | +$331.9K | 75.5% |
| GUGGENHEIM CAPITAL LLC | 49,137 | +2,061 | $1.1M | -$285.9K | 4.4% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 643,356 | +160,774 | $14.8M | +$281.1K | 33.3% |
| Police & Firemen's Retirement System of New Jersey | 39,398 | +54 | $906.2K | -$277.3K | 0.1% |
| Pathstone Holdings, LLC | 34,339 | +413 | $789.8K | -$230.7K | 1.2% |
| COMERICA BANK | 118,422 | +34,711 | $2.7M | +$205.7K | 41.5% |
| Persistent Asset Partners Ltd | 11,029 | +8,947 | $253.7K | +$191.0K | 429.7% |
| ALLIANCEBERNSTEIN L.P. | 27,285 | +577 | $627.6K | -$175.8K | 2.2% |
| Caitong International Asset Management Co., Ltd | 7,611 | +7,600 | $175.1K | +$174.7K | 69090.9% |
| F/M Investments LLC | 73,484 | +11,731 | $1.7M | -$167.4K | 19.0% |
| Scientech Research LLC | 48,032 | +16,727 | $1.1M | +$163.1K | 53.4% |
| Rockefeller Capital Management L.P. | 7,716 | +6,632 | $177.5K | +$144.9K | 611.8% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 28,240 | +1,875 | $649.5K | -$143.5K | 7.1% |
| NOMURA HOLDINGS INC | 95,100 | +17,800 | $2.2M | -$137.9K | 23.0% |
| CITIGROUP INC | 69,511 | +11,922 | $1.6M | -$133.5K | 20.7% |
| AlphaQuest LLC | 5,859 | +5,275 | $134.8K | +$117.2K | 903.3% |
| Headlands Technologies LLC | 28,207 | +2,778 | $648.8K | -$116.1K | 10.9% |
| Quarry LP | 5,000 | +4,890 | $115.0K | +$111.7K | 4445.4% |
| KLP KAPITALFORVALTNING AS | 18,500 | +800 | $425.5K | -$106.9K | 4.5% |
| Virtus Investment Advisers, Inc. | 18,862 | +7,551 | $433.8K | +$93.6K | 66.8% |
| XPONANCE, INC. | 14,390 | +896 | $331.0K | -$74.9K | 6.6% |
| Summit Trail Advisors, LLC | 14,339 | +5,497 | $329.8K | +$63.8K | 62.2% |
| TWO SIGMA INVESTMENTS, LP | 424,049 | +97,869 | $9.8M | -$58.4K | 30.0% |
| VIRGINIA RETIREMENT SYSTEMS ET AL | 20,119 | +6,350 | $462.7K | +$48.6K | 46.1% |
| Walleye Trading LLC | 33,967 | +6,411 | $781.2K | -$47.6K | 23.3% |
| ExodusPoint Capital Management, LP | 137,392 | +30,817 | $3.2M | -$45.8K | 28.9% |
| ADAR1 Capital Management, LLC | 10,000 | +1,000 | $230.0K | -$40.7K | 11.1% |
| MERCER GLOBAL ADVISORS INC /ADV | 13,965 | +2,036 | $321.2K | -$37.6K | 17.1% |
| MetLife Investment Management, LLC | 5,954 | +204 | $136.9K | -$36.0K | 3.5% |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 11,706 | +1,892 | $263.9K | -$28.0K | 19.3% |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 7,791 | +996 | $183.9K | -$20.5K | 14.7% |
| FIDUCIARY TRUST CO | 16,268 | +3,152 | $374.2K | -$20.4K | 24.0% |
| Quantinno Capital Management LP | 49,750 | +11,245 | $1.1M | -$14.0K | 29.2% |
| STRS OHIO | 2,208 | +60 | $50.8K | -$13.8K | 2.8% |
| Sterling Capital Management LLC | 660 | +524 | $15.2K | +$11.1K | 385.3% |
| CAPTRUST FINANCIAL ADVISORS | 11,378 | +2,358 | $261.7K | -$9.6K | 26.1% |
| GAMMA Investing LLC | 585 | +389 | $13.5K | +$7.6K | 198.5% |
| EverSource Wealth Advisors, LLC | 322 | +298 | $7.4K | +$6.7K | 1241.7% |
| QUADRANT CAPITAL GROUP LLC | 400 | +264 | $9.2K | +$5.1K | 194.1% |
| AdvisorNet Financial, Inc | 319 | +231 | $7.3K | +$4.7K | 262.5% |
| Mirae Asset Global Investments Co., Ltd. | 4,688 | +962 | $107.8K | -$4.3K | 25.8% |
| Smartleaf Asset Management LLC | 2,489 | +751 | $56.7K | +$3.9K | 43.2% |
| SBI Securities Co., Ltd. | 174 | +140 | $4.0K | +$3.0K | 411.8% |
| GW&K Investment Management, LLC | 1,375,407 | +225,238 | $31.6K | -$3.0K | 19.6% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,899,661 | +354,382 | $43.7K | -$2.8K | 22.9% |
| Versant Capital Management, Inc | 674 | +243 | $15.5K | +$2.5K | 56.4% |
| Farther Finance Advisors, LLC | 137 | +114 | $3.2K | +$2.5K | 495.6% |
| FIRST HORIZON CORP | 169 | +5 | $3.9K | -$1.0K | 3.0% |
| Global Retirement Partners, LLC | 52 | +41 | $1.2K | +$865 | 372.7% |
| Activest Wealth Management | 38 | +37 | $874 | +$844 | 3700.0% |
| JONES FINANCIAL COMPANIES LLLP | 344 | +56 | $7.9K | -$463 | 19.4% |
| Bare Financial Services, Inc | 45 | +24 | $1.0K | +$403 | 114.3% |
| Parallel Advisors, LLC | 185 | +31 | $4.3K | -$377 | 20.1% |
| CWM, LLC | 13,125 | +9,028 | $302 | +$179 | 220.3% |
| Clearstead Trust, LLC | 82 | +23 | $1.9K | +$111 | 39.0% |
| NATIXIS ADVISORS, L.P. | 21,077 | +1,498 | $485 | -$104 | 7.7% |
| Handelsbanken Fonder AB | 33,523 | +6,400 | $771 | -$45 | 23.6% |
| AMALGAMATED BANK | 7,551 | +325 | $174 | -$43 | 4.5% |
| Daiwa Securities Group Inc. | 7,279 | +371 | $168 | -$40 | 5.4% |
| VAN ECK ASSOCIATES CORP | 5,167 | +2,517 | $119 | +$39 | 95.0% |
Reduced(114)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| FMR LLC | 2,666,249 | -4,617,047 | $61.3M | -$157.8M | -63.4% |
| SANDS CAPITAL MANAGEMENT, LLC | 3,485,724 | -284,129 | $80.2M | -$33.2M | -7.5% |
| DEUTSCHE BANK AG\ | 599,473 | -946,628 | $13.8M | -$32.7M | -61.2% |
| JPMORGAN CHASE & CO | 3,974,030 | -37,399 | $91.4M | -$29.3M | -0.9% |
| RTW INVESTMENTS, LP | 3,000,139 | -258,127 | $69.0M | -$29.0M | -7.9% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,749,268 | -418,461 | $40.2M | -$25.0M | -19.3% |
| BAKER BROS. ADVISORS LP | 2,772,692 | 0 | $63.8M | -$19.6M | 0.0% |
| Invesco Ltd. | 230,271 | -564,578 | $5.3M | -$18.6M | -71.0% |
| Pictet Asset Management Holding SA | 1,231,331 | -226,856 | $26.6M | -$17.4M | -15.6% |
| Schonfeld Strategic Advisors LLC | 764,618 | -379,971 | $17.6M | -$16.8M | -33.2% |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2,019,000 | 0 | $46.4M | -$14.3M | 0.0% |
| FRANKLIN RESOURCES INC | 309,062 | -368,122 | $7.1M | -$13.3M | -54.4% |
| VICTORY CAPITAL MANAGEMENT INC | 19,907 | -278,984 | $457.9K | -$8.5M | -93.3% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 310,108 | -191,055 | $7.1M | -$7.9M | -38.1% |
| Blue Owl Capital Holdings LP | 212,638 | -209,800 | $4.9M | -$7.8M | -49.7% |
| EMERALD ADVISERS, LLC | 212,358 | -206,208 | $4.9M | -$7.7M | -49.3% |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 67,339 | -213,127 | $1.5M | -$6.9M | -76.0% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 280,000 | -150,000 | $6.4M | -$6.5M | -34.9% |
| Hudson Bay Capital Management LP | 73,500 | -191,500 | $1.7M | -$6.3M | -72.3% |
| DIADEMA PARTNERS LP | 100,000 | -182,489 | $2.3M | -$6.2M | -64.6% |
| WCM INVESTMENT MANAGEMENT, LLC | 163,272 | -124,837 | $3.7M | -$5.0M | -43.3% |
| Catalio Capital Management, LP | 162,550 | -128,712 | $3.7M | -$5.0M | -44.2% |
| Polar Capital Holdings Plc | 556,628 | -27,082 | $12.8M | -$4.8M | -4.6% |
| GOLDMAN SACHS GROUP INC | 475,358 | -41,580 | $10.9M | -$4.6M | -8.0% |
| EMERALD MUTUAL FUND ADVISERS TRUST | 120,505 | -122,297 | $2.8M | -$4.5M | -50.4% |
| TWO SIGMA ADVISERS, LP | 481,600 | -36,100 | $11.1M | -$4.5M | -7.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 598,924 | -1,236 | $13.8M | -$4.3M | -0.2% |
| Woodline Partners LP | 171,805 | -101,446 | $4.0M | -$4.3M | -37.1% |
| FRED ALGER MANAGEMENT, LLC | 411,863 | -36,854 | $9.5M | -$4.0M | -8.2% |
| Motley Fool Wealth Management, LLC | 297,486 | -58,054 | $6.8M | -$3.9M | -16.3% |
| Aquatic Capital Management LLC | 87,464 | -103,994 | $2.0M | -$3.7M | -54.3% |
| TUDOR INVESTMENT CORP ET AL | 13,416 | -98,462 | $308.6K | -$3.1M | -88.0% |
| Assenagon Asset Management S.A. | 199,720 | -52,949 | $4.6M | -$3.0M | -20.9% |
| Bank of New York Mellon Corp | 298,706 | -26,139 | $6.9M | -$2.9M | -8.0% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 331,169 | -13,754 | $7.6M | -$2.8M | -4.0% |
| MARSHALL WACE, LLP | 72,168 | -73,926 | $1.7M | -$2.7M | -50.6% |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,094 | -77,300 | $322.9K | -$2.4M | -84.6% |
| SEI INVESTMENTS CO | 153,726 | -36,736 | $3.5M | -$2.2M | -19.3% |
| BARCLAYS PLC | 570,211 | -55,140 | $20.7M | +$1.9M | -8.8% |
| CAPITAL FUND MANAGEMENT S.A. | 150,201 | -26,860 | $3.5M | -$1.9M | -15.2% |
| DLD Asset Management, LP | 77,900 | -32,700 | $1.8M | -$1.5M | -29.6% |
| UBS ASSET MANAGEMENT AMERICAS INC | 204,107 | -2,935 | $4.7M | -$1.5M | -1.4% |
| State of New Jersey Common Pension Fund D | 29,604 | -42,451 | $680.9K | -$1.5M | -58.9% |
| Walleye Capital LLC | 88,184 | -21,449 | $2.0M | -$1.3M | -19.6% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 134,467 | -60,515 | $4.7M | -$1.1M | -31.0% |
| Knott David M Jr | 20,006 | -31,994 | $460.1K | -$1.1M | -61.5% |
| STATE OF WISCONSIN INVESTMENT BOARD | 58,657 | -22,281 | $1.3M | -$1.1M | -27.5% |
| TD Asset Management Inc | 81,964 | -15,034 | $1.9M | -$1.0M | -15.5% |
| B Group, Inc. | 135,000 | 0 | $3.1M | -$955.8K | 0.0% |
| PINNACLE ASSOCIATES LTD | 111,560 | -3,285 | $2.6M | -$888.7K | -2.9% |
| RHUMBLINE ADVISERS | 101,826 | -3,905 | $2.3M | -$838.4K | -3.7% |
| Motley Fool Asset Management LLC | 72,448 | -10,152 | $1.7M | -$818.3K | -12.3% |
| Hennion & Walsh Asset Management, Inc. | 62,173 | -11,621 | $1.4M | -$789.7K | -15.7% |
| Crestwood Advisors Group LLC | 100,131 | -513 | $2.3M | -$724.4K | -0.5% |
| FIRST TRUST ADVISORS LP | 16,642 | -19,692 | $382.8K | -$710.2K | -54.2% |
| NORDEA INVESTMENT MANAGEMENT AB | 58,838 | -6,899 | $1.3M | -$649.2K | -10.5% |
| Parkman Healthcare Partners LLC | 62,030 | -6,606 | $1.4M | -$637.9K | -9.6% |
| B. Metzler seel. Sohn & Co. AG | 12,862 | -17,176 | $295.8K | -$607.7K | -57.2% |
| STIFEL FINANCIAL CORP | 18,997 | -6,461 | $436.9K | -$328.8K | -25.4% |
| WEDGE CAPITAL MANAGEMENT L L P/NC | 42,302 | -877 | $972.9K | -$325.9K | -2.0% |
| ENVESTNET ASSET MANAGEMENT INC | 20,112 | -4,921 | $462.6K | -$290.4K | -19.6% |
| RAYMOND JAMES FINANCIAL INC | 19,851 | -4,706 | $456.6K | -$282.1K | -19.2% |
| NEW YORK STATE COMMON RETIREMENT FUND | 34,024 | -1,322 | $782.6K | -$280.7K | -3.7% |
| JANUS HENDERSON GROUP PLC | 36,543 | 0 | $840.5K | -$258.4K | 0.0% |
| Arizona State Retirement System | 23,969 | -1,207 | $551.3K | -$206.0K | -4.8% |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 27,747 | -312 | $638.2K | -$205.8K | -1.1% |
| OAK RIDGE INVESTMENTS LLC | 13,394 | -3,232 | $308.1K | -$192.0K | -19.4% |
| Voya Investment Management LLC | 19,934 | -679 | $458.5K | -$161.6K | -3.3% |
| Erste Asset Management GmbH | 15,010 | 0 | $296.0K | -$159.7K | 0.0% |
| China Universal Asset Management Co., Ltd. | 15,721 | -1,172 | $361.6K | -$146.6K | -6.9% |
| ADVISOR GROUP HOLDINGS, INC. | 3,116 | -2,879 | $71.7K | -$108.6K | -48.0% |
| COMMERCE BANK | 9,105 | -95 | $209.4K | -$67.3K | -1.0% |
| PNC Financial Services Group, Inc. | 6,647 | -649 | $152.9K | -$66.6K | -8.9% |
| Tower Research Capital LLC (TRC) | 7 | -1,958 | $161 | -$58.9K | -99.6% |
| SRS Capital Advisors, Inc. | 426 | -1,327 | $9.8K | -$42.9K | -75.7% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,554,366 | -755,808 | $35.8K | -$33.7K | -32.7% |
| GF FUND MANAGEMENT CO. LTD. | 1,895 | -178 | $43.6K | -$18.8K | -8.6% |
| Steward Partners Investment Advisory, LLC | 2,010 | 0 | $46.2K | -$14.2K | 0.0% |
| US BANCORP \DE\ | 1,080 | -215 | $24.8K | -$14.1K | -16.6% |
| Larson Financial Group LLC | 140 | -301 | $3.2K | -$10.0K | -68.3% |
| DANSKE BANK A/S | 1,300 | 0 | $29.9K | -$9.2K | 0.0% |
| HUNTINGTON NATIONAL BANK | 1,065 | -27 | $24.5K | -$8.4K | -2.5% |
| ASSETMARK, INC | 1,076 | -8 | $24.7K | -$7.9K | -0.7% |
| ALGERT GLOBAL LLC | 219,232 | -102,401 | $5.0K | -$4.6K | -31.8% |
| SIGNATUREFD, LLC | 540 | -6 | $12.4K | -$4.0K | -1.1% |
| UMB Bank, n.a. | 511 | -12 | $11.8K | -$4.0K | -2.3% |
| SG Americas Securities, LLC | 32,204 | -93,225 | $741 | -$3.0K | -74.3% |
| Quent Capital, LLC | 156 | -60 | $3.6K | -$2.9K | -27.8% |
| Truvestments Capital LLC | 23 | -86 | $529 | -$2.8K | -78.9% |
| New Millennium Group LLC | 200 | 0 | $4.6K | -$1.4K | 0.0% |
| Murphy & Mullick Capital Management Corp | 100 | 0 | $2.3K | -$1.2K | 0.0% |
| DekaBank Deutsche Girozentrale | 57,000 | 0 | $2.9K | +$1.2K | 0.0% |
| Parkside Financial Bank & Trust | 132 | 0 | $3.0K | -$936 | 0.0% |
| GREAT WEST LIFE ASSURANCE CO /CAN/ | 10,623 | -16,309 | $245 | -$572 | -60.5% |
| NISA INVESTMENT ADVISORS, LLC | 80 | 0 | $1.8K | -$566 | 0.0% |
| Clearstead Advisors, LLC | 22 | -13 | $506 | -$547 | -37.1% |
| J.Safra Asset Management Corp | 68 | 0 | $1.6K | -$481 | 0.0% |
| Golden State Wealth Management, LLC | 66 | 0 | $1.5K | -$467 | 0.0% |
| Bell Investment Advisors, Inc | 17 | -11 | $391 | -$452 | -39.3% |
| MASSMUTUAL TRUST CO FSB/ADV | 58 | 0 | $1.3K | -$411 | 0.0% |
| Treasurer of the State of North Carolina | 38,620 | -1,763 | $888 | -$327 | -4.4% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 30 | 0 | $690 | -$212 | 0.0% |
| TD PRIVATE CLIENT WEALTH LLC | 30 | 0 | $690 | -$212 | 0.0% |
| Cromwell Holdings LLC | 14 | 0 | $322 | -$100 | 0.0% |
| Wealth Watch Advisors, INC | 13 | 0 | $299 | -$92 | 0.0% |
| WPG Advisers, LLC | 11 | 0 | $253 | -$78 | 0.0% |
| Transamerica Financial Advisors, Inc. | 9 | 0 | $207 | -$64 | 0.0% |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 8,946 | 0 | $206 | -$63 | 0.0% |
| SouthState Corp | 5 | 0 | $115 | -$36 | 0.0% |
| Caitlin John, LLC | 5 | 0 | $115 | -$35 | 0.0% |
| Covestor Ltd | 1,456 | -331 | $34 | -$20 | -18.5% |
| HANTZ FINANCIAL SERVICES, INC. | 64 | 0 | $1 | -$1 | 0.0% |
| FARALLON CAPITAL MANAGEMENT LLC | 7,000 | 0 | $210.6K | $0 | 0.0% |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | $0 | $0 | — |
Sold Out(68)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| VANGUARD GROUP INC | 10,263,815 | $236.1M | +131,087 | 1.3% |
| BlackRock, Inc. | 6,631,554 | $152.5M | +206,291 | 3.2% |
| STATE STREET CORP | 4,303,046 | $99.0M | +610,559 | 16.5% |
| JPMORGAN CHASE & CO | 3,974,030 | $91.4M | -37,399 | -0.9% |
| SANDS CAPITAL MANAGEMENT, LLC | 3,485,724 | $80.2M | -284,129 | -7.5% |
| RTW INVESTMENTS, LP | 3,000,139 | $69.0M | -258,127 | -7.9% |
| BAKER BROS. ADVISORS LP | 2,772,692 | $63.8M | 0 | 0.0% |
| FMR LLC | 2,666,249 | $61.3M | -4,617,047 | -63.4% |
| CITADEL ADVISORS LLC | 2,661,725 | $61.2M | +2,070,172 | 349.9% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,461,910 | $56.6M | +516,781 | 26.6% |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2,019,000 | $46.4M | 0 | 0.0% |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 1,965,084 | $45.2M | +895,986 | 83.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,838,208 | $42.3M | +257,701 | 16.3% |
| MORGAN STANLEY | 1,826,295 | $42.0M | +916,112 | 100.7% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,749,268 | $40.2M | -418,461 | -19.3% |
| abrdn plc | 1,469,951 | $33.8M | +496,295 | 51.0% |
| AQR CAPITAL MANAGEMENT LLC | 1,360,497 | $31.3M | +614,315 | 82.3% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,280,716 | $29.5M | +442,590 | 52.8% |
| Rock Springs Capital Management LP | 1,267,241 | $29.1M | +20,900 | 1.7% |
| NORGES BANK | 1,261,026 | $29.0M | +320,400 | 34.1% |
New & Closed Positions this quarter
Closed Positions
68 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for RARE against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.