Institutional Manager · CIK 0001281446
GREAT POINT PARTNERS LLC
Greenwich, CT · File #028-11743
Latest AUM
$308.4M
Positions
29
Top-10 Concentration
62.0%
Filings
12
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202529 pos · $308.4M
- 13F HOLDINGS REPORTQ/E Sep 202530 pos · $242.5M
- 13F HOLDINGS REPORTQ/E Jun 202526 pos · $153.8M
- 13F HOLDINGS REPORTQ/E Mar 202532 pos · $188.8M
- 13F HOLDINGS REPORTQ/E Dec 202426 pos · $212.2M
- 13F HOLDINGS REPORTQ/E Sep 202430 pos · $339.8M
- 13F HOLDINGS REPORTQ/E Jun 202433 pos · $522.0M
- 13F HOLDINGS REPORTQ/E Mar 202435 pos · $641.6M
- 13F HOLDINGS REPORTQ/E Dec 202342 pos · $549.0M
- 13F HOLDINGS REPORTQ/E Sep 202340 pos · $510.8M
- 13F HOLDINGS REPORTQ/E Jun 202344 pos · $509.3M
- 13F HOLDINGS REPORTQ/E Mar 202342 pos · $510.2M
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | APOGEE THERAPEUTICS INC | APGE | 374,000 | $28.2M | 9.15% |
| 2 | AMYLYX PHARMACEUTICALS INC | AMLX | 1,750,000 | $21.1M | 6.85% |
| 3 | ZURA BIO LTD | ZURA | 3,815,930 | $20.0M | 6.48% |
| 4 | DISC MEDICINE INC | IRON | 250,000 | $19.9M | 6.44% |
| 5 | RAPT THERAPEUTICS INC | 75382E208 | 581,187 | $19.7M | 6.38% |
| 6 | IMMUNOVANT INC | IMVT | 750,000 | $19.1M | 6.18% |
| 7 | SOLENO THERAPEUTICS INC | SLNO | 400,000 | $18.5M | 6.00% |
| 8 | VOR BIOPHARMA INC | VOR | 1,370,107 | $17.9M | 5.81% |
| 9 | DIANTHUS THERAPEUTICS INC | DNTH | 350,000 | $14.4M | 4.68% |
| 10 | JADE BIOSCIENCES INC | JBIO | 806,273 | $12.4M | 4.03% |
| 11 | KALVISTA PHARMACEUTICALS INC | KALV | 685,632 | $11.1M | 3.59% |
| 12 | CONTINEUM THERAPEUTICS INC | CTNM | 800,000 | $9.1M | 2.96% |
| 13 | EUPRAXIA PHARMACEUTICALS INC | EPRX | 1,200,000 | $9.1M | 2.94% |
| 14 | FULCRUM THERAPEUTICS INC | FULC | 800,000 | $9.0M | 2.93% |
| 15 | NEKTAR THERAPEUTICS | NKTR | 210,732 | $8.9M | 2.89% |
| 16 | UPSTREAM BIO INC | UPB | 300,000 | $8.1M | 2.64% |
| 17 | NEUROGENE INC | NGNE | 350,000 | $7.2M | 2.34% |
| 18 | ULTRAGENYX PHARMACEUTICAL IN | RARE | 300,000 | $6.9M | 2.24% |
| 19 | CONTEXT THERAPEUTICS INC | CNTX | 4,683,711 | $6.9M | 2.23% |
| 20 | CULLINAN THERAPEUTICS INC | CGEM | 634,032 | $6.6M | 2.13% |