New Positions
30 managers initiated
Top five by reported value
Pharvaris NV NASDAQ NMS - GLOBAL MARKET:PHVS
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
30 new42 added33 reduced8 exited
Total Institutional Holders
105
as of 2025-12-31
Top Holder
GENERAL ATLANTIC, L.P.
$222.9M
Largest QoQ Increase
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)
+683,578 sh
Largest QoQ Decrease
Paradigm Biocapital Advisors LP
-1,835,494 sh
New Positions(30)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Elmind Capital, LP | 475,750 | +475,750 | $13.2M | +$13.2M | — |
| Eversept Partners, LP | 439,177 | +439,177 | $12.2M | +$12.2M | — |
| ORBIMED ADVISORS LLC | 205,400 | +205,400 | $5.7M | +$5.7M | — |
| Kalehua Capital Management LLC | 198,772 | +198,772 | $5.5M | +$5.5M | — |
| HighVista Strategies LLC | 162,370 | +162,370 | $4.5M | +$4.5M | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 121,724 | +121,724 | $3.4M | +$3.4M | — |
| Squarepoint Ops LLC | 100,359 | +100,359 | $2.8M | +$2.8M | — |
| TWO SIGMA ADVISERS, LP | 89,600 | +89,600 | $2.5M | +$2.5M | — |
| Trexquant Investment LP | 84,353 | +84,353 | $2.3M | +$2.3M | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 83,947 | +83,947 | $2.3M | +$2.3M | — |
| STEMPOINT CAPITAL LP | 58,389 | +58,389 | $1.6M | +$1.6M | — |
| Seven Fleet Capital Management LP | 55,342 | +55,342 | $1.5M | +$1.5M | — |
| ALPS ADVISORS INC | 52,592 | +52,592 | $1.5M | +$1.5M | — |
| Quadrature Capital Ltd | 28,920 | +28,920 | $802.5K | +$802.5K | — |
| Jump Financial, LLC | 26,300 | +26,300 | $729.8K | +$729.8K | — |
| SummitTX Capital, L.P. | 22,859 | +22,859 | $634.3K | +$634.3K | — |
| PSP Research LLC | 20,511 | +20,511 | $569.2K | +$569.2K | — |
| Verition Fund Management LLC | 17,898 | +17,898 | $496.7K | +$496.7K | — |
| Qube Research & Technologies Ltd | 14,706 | +14,706 | $408.1K | +$408.1K | — |
| OCCUDO QUANTITATIVE STRATEGIES LP | 12,349 | +12,349 | $342.7K | +$342.7K | — |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 8,911 | +8,911 | $247.3K | +$247.3K | — |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | 5,000 | +5,000 | $138.8K | +$138.8K | — |
| Quantbot Technologies LP | 4,260 | +4,260 | $118.2K | +$118.2K | — |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,979 | +3,979 | $110.4K | +$110.4K | — |
| Mirae Asset Global Investments Co., Ltd. | 3,113 | +3,113 | $86.4K | +$86.4K | — |
| BARCLAYS PLC | 2,796 | +2,796 | $49.2K | +$49.2K | — |
| GF FUND MANAGEMENT CO. LTD. | 1,258 | +1,258 | $34.9K | +$34.9K | — |
| Tower Research Capital LLC (TRC) | 471 | +471 | $13.1K | +$13.1K | — |
| WELLS FARGO & COMPANY/MN | 450 | +450 | $12.5K | +$12.5K | — |
| Daiwa Securities Group Inc. | 213 | +213 | $6 | +$6 | — |
Added To(42)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 3,126,042 | +683,578 | $86.7M | +$25.8M | 28.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 1,905,793 | +171,050 | $52.9M | +$9.6M | 9.9% |
| Saturn V Capital Management LLC | 1,140,033 | +253,701 | $31.6M | +$9.5M | 28.6% |
| BlackRock, Inc. | 708,558 | +294,141 | $19.7M | +$9.3M | 71.0% |
| Ikarian Capital, LLC | 486,856 | +276,691 | $13.5M | +$8.3M | 131.7% |
| Point72 Asset Management, L.P. | 711,625 | +192,244 | $19.7M | +$6.8M | 37.0% |
| D. E. Shaw & Co., Inc. | 260,572 | +237,686 | $7.2M | +$6.7M | 1038.6% |
| Patient Square Capital LP | 542,696 | +197,315 | $15.1M | +$6.4M | 57.1% |
| TWO SIGMA INVESTMENTS, LP | 215,188 | +204,581 | $6.0M | +$5.7M | 1928.7% |
| MORGAN STANLEY | 248,334 | +190,071 | $6.9M | +$5.4M | 326.2% |
| MILLENNIUM MANAGEMENT LLC | 248,858 | +142,310 | $6.9M | +$4.2M | 133.6% |
| GOLDMAN SACHS GROUP INC | 160,910 | +146,434 | $4.5M | +$4.1M | 1011.6% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 158,019 | +145,946 | $4.1M | +$3.9M | 1208.9% |
| Soleus Capital Management, L.P. | 702,052 | +55,000 | $19.5M | +$3.3M | 8.5% |
| Sofinnova Investments, Inc. | 745,169 | +5,293 | $20.7M | +$2.2M | 0.7% |
| JANE STREET GROUP, LLC | 85,711 | +64,514 | $2.4M | +$1.8M | 304.4% |
| BNP PARIBAS ARBITRAGE, SNC | 59,037 | +58,624 | $1.6M | +$1.6M | 14194.7% |
| ADAR1 Capital Management, LLC | 85,528 | +51,404 | $2.4M | +$1.5M | 150.6% |
| BOOTHBAY FUND MANAGEMENT, LLC | 157,117 | +21,936 | $4.4M | +$987.2K | 16.2% |
| STATE STREET CORP | 161,499 | +18,724 | $4.5M | +$919.4K | 13.1% |
| TD Asset Management Inc | 120,248 | +15,892 | $3.3M | +$733.2K | 15.2% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 79,890 | +20,100 | $2.1M | +$605.4K | 33.6% |
| UBS Group AG | 137,734 | +6,982 | $3.8M | +$559.9K | 5.3% |
| CITADEL ADVISORS LLC | 135,069 | +5,331 | $3.7M | +$511.2K | 4.1% |
| Birchview Capital, LP | 29,847 | +15,000 | $828.3K | +$457.8K | 101.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 86,801 | +8,261 | $2.4M | +$449.1K | 10.5% |
| XTX Topco Ltd | 18,568 | +10,355 | $515.3K | +$310.3K | 126.1% |
| NORTHERN TRUST CORP | 81,035 | +3,080 | $2.2M | +$303.7K | 4.0% |
| DEUTSCHE BANK AG\ | 56,388 | +4,583 | $1.6M | +$272.2K | 8.8% |
| China Universal Asset Management Co., Ltd. | 10,438 | +7,438 | $289.7K | +$214.8K | 247.9% |
| MARSHALL WACE, LLP | 31,832 | +4,736 | $883.3K | +$207.3K | 17.5% |
| Swiss National Bank | 44,757 | +2,400 | $1.2M | +$185.2K | 5.7% |
| Palumbo Wealth Management LLC | 20,182 | +3,541 | $560.1K | +$144.9K | 21.3% |
| Virtus Investment Advisers, Inc. | 11,011 | +4,407 | $305.6K | +$140.8K | 66.7% |
| Police & Firemen's Retirement System of New Jersey | 8,239 | +2,750 | $228.6K | +$91.7K | 50.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 23,982 | +520 | $665.5K | +$80.1K | 2.2% |
| BANK OF AMERICA CORP /DE/ | 19,557 | +901 | $542.7K | +$77.2K | 4.8% |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 7,569 | +1,300 | $210.0K | +$53.6K | 20.7% |
| CITIGROUP INC | 1,787 | +1,223 | $49.6K | +$35.5K | 216.8% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 941,605 | +124,797 | $26.1K | +$5.8K | 15.3% |
| Royal Bank of Canada | 80 | +22 | $2.0K | +$1.0K | 37.9% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 5,510 | +2,249 | $153 | +$72 | 69.0% |
Reduced(33)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GENERAL ATLANTIC, L.P. | 8,031,252 | 0 | $222.9M | +$22.5M | 0.0% |
| FMR LLC | 6,399,158 | 0 | $177.6M | +$17.9M | 0.0% |
| Foresite Capital Management IV, LLC | 4,778,581 | 0 | $132.6M | +$13.4M | 0.0% |
| venBio Partners LLC | 4,639,304 | 0 | $128.7M | +$13.0M | 0.0% |
| VIKING GLOBAL INVESTORS LP | 3,653,310 | 0 | $101.4M | +$10.2M | 0.0% |
| EQT Fund Management S.a r.l. | 3,424,609 | 0 | $95.0M | +$9.6M | 0.0% |
| COMMODORE CAPITAL LP | 1,889,445 | -529,031 | $52.4M | -$7.9M | -21.9% |
| Novo Holdings A/S | 1,750,000 | 0 | $48.6M | +$4.9M | 0.0% |
| Cormorant Asset Management, LP | 1,083,000 | -280,200 | $30.1M | -$4.0M | -20.6% |
| 5AM Venture Management, LLC | 797,600 | 0 | $22.1M | +$2.2M | 0.0% |
| Balyasny Asset Management LLC | 496,259 | -129,499 | $13.8M | -$1.8M | -20.7% |
| Rock Springs Capital Management LP | 623,402 | 0 | $17.3M | +$1.7M | 0.0% |
| Bain Capital Life Sciences Investors, LLC | 2,802,081 | -379,194 | $77.8M | -$1.6M | -11.9% |
| GREAT POINT PARTNERS LLC | 82,800 | -72,305 | $2.3M | -$1.6M | -46.6% |
| SPHERA FUNDS MANAGEMENT LTD. | 63,953 | -55,453 | $1.8M | -$1.2M | -46.4% |
| TUDOR INVESTMENT CORP ET AL | 32,028 | -45,863 | $888.8K | -$1.1M | -58.9% |
| BAKER BROS. ADVISORS LP | 375,000 | 0 | $10.4M | +$1.1M | 0.0% |
| Logos Global Management LP | 100,000 | -50,000 | $2.8M | -$967.5K | -33.3% |
| Kynam Capital Management, LP | 640,395 | -34,605 | $17.8M | +$929.7K | -5.1% |
| Octagon Capital Advisors LP | 671,465 | -51,130 | $18.6M | +$604.4K | -7.1% |
| TFG Asset Management GP Ltd | 194,612 | 0 | $5.4M | +$544.9K | 0.0% |
| Alyeska Investment Group, L.P. | 125,000 | 0 | $3.5M | +$350.0K | 0.0% |
| AMUNDI | 27,640 | -13,877 | $767.0K | -$198.3K | -33.4% |
| JPMORGAN CHASE & CO | 21,942 | -5,143 | $608.9K | -$66.9K | -19.0% |
| Legal & General Group Plc | 22,666 | 0 | $629.0K | +$63.5K | 0.0% |
| VANGUARD GROUP INC | 19,310 | 0 | $535.9K | +$54.1K | 0.0% |
| Nuveen, LLC | 17,007 | 0 | $471.9K | +$47.6K | 0.0% |
| ALLIANCEBERNSTEIN L.P. | 8,980 | 0 | $249.2K | +$25.1K | 0.0% |
| KLP KAPITALFORVALTNING AS | 5,800 | 0 | $160.9K | +$16.2K | 0.0% |
| Polar Capital Holdings Plc | 237,962 | -26,731 | $6.6M | -$644 | -10.1% |
| HRT FINANCIAL LP | 14,764 | -11,438 | $409 | -$244 | -43.6% |
| SBI Securities Co., Ltd. | 1 | -2 | $28 | -$47 | -66.7% |
| Centerpoint Advisors, LLC | 100 | 0 | $3 | +$1 | 0.0% |
Sold Out(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 0 | -1,835,494 | $0 | -$45.8M | — |
| VR Adviser, LLC | 0 | -674,599 | $0 | -$16.8M | — |
| Integral Health Asset Management, LLC | 0 | -200,000 | $0 | -$5.0M | — |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | -183,903 | $0 | -$4.6M | — |
| Woodline Partners LP | 0 | -100,000 | $0 | -$2.5M | — |
| Cubist Systematic Strategies, LLC | 0 | -11,639 | $0 | -$290.4K | — |
| Quarry LP | 0 | -442 | $0 | -$11.0K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -1 | $0 | -$25 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
New & Closed Positions this quarter
Closed Positions
8 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for PHVS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.