Institutional Manager · CIK 0001704132
Foresite Capital Management IV, LLC
Larkspur, CA · File #028-18415
Latest AUM
$229.7M
Positions
7
Top-10 Concentration
100.0%
Filings
9
Portfolio Value Over Time
2024-03
2024-06
2024-09
2024-12
2025-03
2025-06
2025-09
2025-12
Biggest QoQ Changes
Ranked by conviction flow (share change × current price) so mark-to-market moves don't dominate. Price effect column shows how much of the $ change was just the stock moving.
| Action | Issuer | Ticker / CUSIP | Δ Shares | Flow ($) | Price Effect |
|---|---|---|---|---|---|
| NEW | Alector, Inc. | ALEC | +3,887,200 | +$6.1M | $0 |
| REDUCE | CYTOKINETICS INC | CYTK | 0 | $0 | +$3.9M |
| REDUCE | Lyell Immunopharma, Inc. | LYEL | 0 | $0 | +$11.6M |
| REDUCE | Maze Therapeutics, Inc. | MAZE | 0 | $0 | +$8.1M |
| REDUCE | Pharvaris N.V. | PHVS | 0 | $0 | +$13.4M |
| REDUCE | Relay Therapeutics, Inc. | RLAY | 0 | $0 | +$3.2M |
| REDUCE | Xenon Pharmaceuticals Inc. | XENE | 0 | $0 | +$747,200 |
Sector Allocation
Filing History
- 13F HOLDINGS REPORTQ/E Dec 20257 pos · $229.7M
- 13F HOLDINGS REPORTQ/E Sep 20256 pos · $182.6M
- 13F HOLDINGS REPORTQ/E Jun 20256 pos · $123.8M
- 13F HOLDINGS REPORTQ/E Mar 20255 pos · $111.1M
- 13F HOLDINGS REPORTQ/E Dec 20244 pos · $108.8M
- 13F HOLDINGS REPORTQ/E Sep 20245 pos · $153.0M
- 13F HOLDINGS REPORTQ/E Jun 20244 pos · $148.8M
- 13F HOLDINGS REPORTQ/E Mar 20245 pos · $197.9M
- 13F HOLDINGS REPORTQ/E Dec 20237 pos · $180.0M
Top 7 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | Pharvaris N.V. | PHVS | 4,778,581 | $132.6M | 57.73% |
| 2 | CYTOKINETICS INC | CYTK | 458,295 | $29.1M | 12.68% |
| 3 | Lyell Immunopharma, Inc. | LYEL | 800,399 | $24.6M | 10.72% |
| 4 | Maze Therapeutics, Inc. | MAZE | 522,657 | $21.7M | 9.43% |
| 5 | Relay Therapeutics, Inc. | RLAY | 1,000,000 | $8.5M | 3.68% |
| 6 | Xenon Pharmaceuticals Inc. | XENE | 160,000 | $7.2M | 3.12% |
| 7 | Alector, Inc. | ALEC | 3,887,200 | $6.1M | 2.64% |