Institutional Manager · CIK 0001831942
COMMODORE CAPITAL LP
NEW YORK, NY · File #028-20976
Latest AUM
$1.50B
Positions
33
Top-10 Concentration
55.8%
Filings
12
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 202533 pos · $1.50B
- 13F HOLDINGS REPORTQ/E Sep 202537 pos · $2.05B
- 13F HOLDINGS REPORTQ/E Jun 202533 pos · $1.42B
- 13F HOLDINGS REPORTQ/E Mar 202531 pos · $1.36B
- 13F HOLDINGS REPORTQ/E Dec 202431 pos · $1.36B
- 13F HOLDINGS REPORTQ/E Sep 202436 pos · $1.60B
- 13F HOLDINGS REPORTQ/E Jun 202435 pos · $1.47B
- 13F HOLDINGS REPORTQ/E Mar 202439 pos · $1.50B
- 13F HOLDINGS REPORTQ/E Dec 202330 pos · $855.5M
- 13F HOLDINGS REPORTQ/E Sep 202326 pos · $889.8M
- 13F HOLDINGS REPORTQ/E Jun 202332 pos · $656.8M
- 13F HOLDINGS REPORTQ/E Mar 202335 pos · $663,544
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | RELAY THERAPEUTICS INC | RLAY | 17,000,000 | $143.8M | 9.57% |
| 2 | ALKERMES PLC | ALKS | 3,550,000 | $99.3M | 6.61% |
| 3 | TYRA BIOSCIENCES INC | TYRA | 3,375,000 | $88.7M | 5.91% |
| 4 | XENON PHARMACEUTICALS INC | XENE | 1,800,000 | $80.7M | 5.37% |
| 5 | SPYRE THERAPEUTICS INC | SYRE | 2,388,245 | $78.2M | 5.21% |
| 6 | COGENT BIOSCIENCES INC | COGT | 2,196,845 | $78.0M | 5.19% |
| 7 | ENLIVEN THERAPEUTICS INC | ELVN | 4,692,809 | $72.3M | 4.81% |
| 8 | CELLDEX THERAPEUTICS INC NEW | CLDX | 2,565,000 | $69.7M | 4.64% |
| 9 | AMYLYX PHARMACEUTICALS INC | AMLX | 5,650,000 | $68.3M | 4.54% |
| 10 | TERNS PHARMACEUTICALS INC | TERN | 1,475,000 | $59.6M | 3.97% |
| 11 | KYMERA THERAPEUTICS INC | KYMR | 750,000 | $58.4M | 3.88% |
| 12 | SOLENO THERAPEUTICS INC | SLNO | 1,200,000 | $55.6M | 3.70% |
| 13 | NUVALENT INC | NUVL | 550,000 | $55.3M | 3.68% |
| 14 | ORUKA THERAPEUTICS INC | ORKA | 1,753,054 | $53.1M | 3.54% |
| 15 | PHARVARIS N V | PHVS | 1,889,445 | $52.4M | 3.49% |
| 16 | NURIX THERAPEUTICS INC | NRIX | 2,275,000 | $43.2M | 2.87% |
| 17 | PROTAGONIST THERAPEUTICS INC | PTGX | 450,000 | $39.3M | 2.62% |
| 18 | ASSEMBLY BIOSCIENCES INC | ASMB | 1,000,000 | $34.0M | 2.26% |
| 19 | LB PHARMACEUTICALS INC | LBRX | 1,500,000 | $33.4M | 2.22% |
| 20 | CYTOMX THERAPEUTICS INC | CTMX | 7,692,300 | $32.8M | 2.18% |