New Positions
89 managers initiated
Top five by reported value
- Siren, L.L.C.$82.5M
- Cormorant Asset Management, LP$68.8M
- RA CAPITAL MANAGEMENT, L.P.$65.0M
- Vestal Point Capital, LP$41.3M
- Polar Capital Holdings Plc$34.5M
Olema Pharmaceuticals Inc NASDAQ NMS - GLOBAL MARKET:OLMA
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
89 new60 added56 reduced12 exited
Total Institutional Holders
204
as of 2025-12-31
Top Holder
Bain Capital Life Sciences Investors, LLC
$212.7M
Largest QoQ Increase
FMR LLC
+4,993,670 sh
Largest QoQ Decrease
Deep Track Capital, LP
-3,470,172 sh
New Positions(89)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Siren, L.L.C. | 3,300,700 | +3,300,700 | $82.5M | +$82.5M | — |
| Cormorant Asset Management, LP | 2,750,000 | +2,750,000 | $68.8M | +$68.8M | — |
| RA CAPITAL MANAGEMENT, L.P. | 2,600,000 | +2,600,000 | $65.0M | +$65.0M | — |
| Vestal Point Capital, LP | 1,650,000 | +1,650,000 | $41.3M | +$41.3M | — |
| Polar Capital Holdings Plc | 1,380,450 | +1,380,450 | $34.5M | +$34.5M | — |
| Defilade Capital Management, L.P. | 1,234,634 | +1,234,634 | $30.9M | +$30.9M | — |
| SAMLYN CAPITAL, LLC | 1,069,543 | +1,069,543 | $26.7M | +$26.7M | — |
| JENNISON ASSOCIATES LLC | 963,997 | +963,997 | $24.1M | +$24.1M | — |
| Ikarian Capital, LLC | 958,654 | +958,654 | $24.0M | +$24.0M | — |
| First Turn Management, LLC | 617,714 | +617,714 | $15.4M | +$15.4M | — |
| EVENTIDE ASSET MANAGEMENT, LLC | 569,000 | +569,000 | $14.2M | +$14.2M | — |
| Holocene Advisors, LP | 506,001 | +506,001 | $12.7M | +$12.7M | — |
| MARSHALL WACE, LLP | 360,394 | +360,394 | $9.0M | +$9.0M | — |
| Skandinaviska Enskilda Banken AB (publ) | 281,687 | +281,687 | $7.0M | +$7.0M | — |
| BOOTHBAY FUND MANAGEMENT, LLC | 274,086 | +274,086 | $6.9M | +$6.9M | — |
| Catalio Capital Management, LP | 267,058 | +267,058 | $6.7M | +$6.7M | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 210,000 | +210,000 | $5.3M | +$5.3M | — |
| PERCEPTIVE ADVISORS LLC | 165,713 | +165,713 | $4.1M | +$4.1M | — |
| ExodusPoint Capital Management, LP | 150,670 | +150,670 | $3.8M | +$3.8M | — |
| TD Asset Management Inc | 136,400 | +136,400 | $3.4M | +$3.4M | — |
| Burkehill Global Management, LP | 125,000 | +125,000 | $3.1M | +$3.1M | — |
| Schonfeld Strategic Advisors LLC | 113,978 | +113,978 | $2.8M | +$2.8M | — |
| Brevan Howard Capital Management LP | 107,950 | +107,950 | $2.7M | +$2.7M | — |
| Jump Financial, LLC | 100,274 | +100,274 | $2.5M | +$2.5M | — |
| Rock Springs Capital Management LP | 98,240 | +98,240 | $2.5M | +$2.5M | — |
| Harvest Investment Services, LLC | 68,723 | +68,723 | $1.7M | +$1.7M | — |
| Nicholas Investment Partners, LP | 64,757 | +64,757 | $1.6M | +$1.6M | — |
| FRED ALGER MANAGEMENT, LLC | 64,484 | +64,484 | $1.6M | +$1.6M | — |
| Swedbank AB | 55,100 | +55,100 | $1.4M | +$1.4M | — |
| ACT CAPITAL MANAGEMENT, LLC | 53,500 | +53,500 | $1.3M | +$1.3M | — |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 50,000 | +50,000 | $1.3M | +$1.3M | — |
| NOMURA HOLDINGS INC | 50,000 | +50,000 | $1.3M | +$1.3M | — |
| Trexquant Investment LP | 49,754 | +49,754 | $1.2M | +$1.2M | — |
| NEOS Investment Management LLC | 45,170 | +45,170 | $1.1M | +$1.1M | — |
| Rafferty Asset Management, LLC | 45,005 | +45,005 | $1.1M | +$1.1M | — |
| TEMA ETFS LLC | 44,505 | +44,505 | $1.1M | +$1.1M | — |
| RAYMOND JAMES FINANCIAL INC | 40,647 | +40,647 | $1.0M | +$1.0M | — |
| Y-Intercept (Hong Kong) Ltd | 37,199 | +37,199 | $930.0K | +$930.0K | — |
| STATE OF WISCONSIN INVESTMENT BOARD | 34,940 | +34,940 | $873.5K | +$873.5K | — |
| Verition Fund Management LLC | 33,382 | +33,382 | $834.5K | +$834.5K | — |
| Jain Global LLC | 30,160 | +30,160 | $754.0K | +$754.0K | — |
| Ishara Investments LP | 30,000 | +30,000 | $750.0K | +$750.0K | — |
| Engineers Gate Manager LP | 26,207 | +26,207 | $655.2K | +$655.2K | — |
| Empire Financial Management Company, LLC | 25,000 | +25,000 | $625.0K | +$625.0K | — |
| AXQ CAPITAL, LP | 21,323 | +21,323 | $533.1K | +$533.1K | — |
| Shay Capital LLC | 21,000 | +21,000 | $525.0K | +$525.0K | — |
| Huntleigh Advisors, Inc. | 20,130 | +20,130 | $503.3K | +$503.3K | — |
| PSP Research LLC | 19,063 | +19,063 | $476.6K | +$476.6K | — |
| Jefferies Financial Group Inc. | 18,000 | +18,000 | $450.0K | +$450.0K | — |
| Scientech Research LLC | 17,474 | +17,474 | $436.9K | +$436.9K | — |
| PROFUND ADVISORS LLC | 17,381 | +17,381 | $434.5K | +$434.5K | — |
| Entropy Technologies, LP | 17,304 | +17,304 | $432.6K | +$432.6K | — |
| Aquatic Capital Management LLC | 15,314 | +15,314 | $382.9K | +$382.9K | — |
| Inscription Capital, LLC | 15,273 | +15,273 | $381.8K | +$381.8K | — |
| POLEN CAPITAL MANAGEMENT LLC | 15,206 | +15,206 | $380.1K | +$380.1K | — |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 38,078 | +38,078 | $334.3K | +$334.3K | — |
| Cetera Investment Advisers | 10,500 | +10,500 | $262.5K | +$262.5K | — |
| STRS OHIO | 10,500 | +10,500 | $262.5K | +$262.5K | — |
| Blueshift Asset Management, LLC | 10,237 | +10,237 | $255.9K | +$255.9K | — |
| Wealthspire Advisors, LLC | 10,172 | +10,172 | $254.3K | +$254.3K | — |
| EP Wealth Advisors, LLC | 10,009 | +10,009 | $250.2K | +$250.2K | — |
| D. E. Shaw & Co., Inc. | 9,954 | +9,954 | $248.8K | +$248.8K | — |
| OPPENHEIMER & CO INC | 9,500 | +9,500 | $237.5K | +$237.5K | — |
| Persistent Asset Partners Ltd | 9,069 | +9,069 | $226.7K | +$226.7K | — |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 8,880 | +8,880 | $222.0K | +$222.0K | — |
| SEI INVESTMENTS CO | 8,259 | +8,259 | $206.5K | +$206.5K | — |
| Quantbot Technologies LP | 8,046 | +8,046 | $201.2K | +$201.2K | — |
| Sanctuary Advisors, LLC | 38,956 | +38,956 | $154.6K | +$154.6K | — |
| Bellevue Group AG | 3,902 | +3,902 | $97.5K | +$97.5K | — |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | 3,500 | +3,500 | $87.5K | +$87.5K | — |
| Torren Management, LLC | 1,759 | +1,759 | $44.0K | +$44.0K | — |
| JONES FINANCIAL COMPANIES LLLP | 1,191 | +1,191 | $29.8K | +$29.8K | — |
| US BANCORP \DE\ | 538 | +538 | $13.4K | +$13.4K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 412 | +412 | $10.3K | +$10.3K | — |
| Allworth Financial LP | 372 | +372 | $9.3K | +$9.3K | — |
| Steward Partners Investment Advisory, LLC | 360 | +360 | $9.0K | +$9.0K | — |
| Rockefeller Capital Management L.P. | 150 | +150 | $3.8K | +$3.8K | — |
| Greenline Wealth Management LLC | 111 | +111 | $2.8K | +$2.8K | — |
| SG Americas Securities, LLC | 69,382 | +69,382 | $1.7K | +$1.7K | — |
| Atlantic Edge Private Wealth Management, LLC | 50 | +50 | $1.3K | +$1.3K | — |
| Clearstead Advisors, LLC | 43 | +43 | $1.1K | +$1.1K | — |
| Virtu Financial LLC | 42,437 | +42,437 | $1.1K | +$1.1K | — |
| Hurley Capital, LLC | 29 | +29 | $725 | +$725 | — |
| ACADIAN ASSET MANAGEMENT LLC | 19,088 | +19,088 | $477 | +$477 | — |
| IFP Advisors, Inc | 12 | +12 | $209 | +$209 | — |
| Hughes Financial Services, LLC | 1 | +1 | $25 | +$25 | — |
| FNY Investment Advisers, LLC | 1,742 | +1,742 | $16 | +$16 | — |
| Activest Wealth Management | 1 | +1 | $13 | +$13 | — |
| HAZLETT, BURT & WATSON, INC. | 50 | +50 | $1 | +$1 | — |
Added To(60)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 8,508,641 | +1,664,687 | $212.7M | +$145.7M | 24.3% |
| JANUS HENDERSON GROUP PLC | 6,710,194 | +3,124,345 | $167.9M | +$132.8M | 87.1% |
| FMR LLC | 5,023,092 | +4,993,670 | $125.6M | +$125.3M | 16972.6% |
| Paradigm Biocapital Advisors LP | 7,544,172 | +750,000 | $188.6M | +$122.1M | 11.0% |
| BlackRock, Inc. | 5,563,260 | +836,866 | $139.1M | +$92.8M | 17.7% |
| VANGUARD GROUP INC | 3,561,355 | +364,035 | $89.0M | +$57.7M | 11.4% |
| STATE STREET CORP | 1,884,399 | +790,825 | $47.1M | +$36.4M | 72.3% |
| CITADEL ADVISORS LLC | 1,374,407 | +124,492 | $34.4M | +$22.1M | 10.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 904,124 | +791,847 | $22.6M | +$21.5M | 705.3% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 953,600 | +99,600 | $23.8M | +$15.5M | 11.7% |
| GOLDMAN SACHS GROUP INC | 817,889 | +14,008 | $20.4M | +$12.6M | 1.7% |
| MILLENNIUM MANAGEMENT LLC | 498,490 | +167,036 | $12.5M | +$9.2M | 50.4% |
| Hennion & Walsh Asset Management, Inc. | 447,046 | +202,970 | $11.2M | +$8.8M | 83.2% |
| TWO SIGMA INVESTMENTS, LP | 393,658 | +284,132 | $9.8M | +$8.8M | 259.4% |
| Squarepoint Ops LLC | 328,680 | +314,589 | $8.2M | +$8.1M | 2232.6% |
| JPMORGAN CHASE & CO | 268,471 | +238,340 | $6.7M | +$6.4M | 791.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 407,141 | +12,014 | $10.2M | +$6.3M | 3.0% |
| Point72 Asset Management, L.P. | 321,990 | +76,572 | $8.0M | +$5.6M | 31.2% |
| Birchview Capital, LP | 269,000 | +95,000 | $6.7M | +$5.0M | 54.6% |
| Nuveen, LLC | 229,469 | +101,249 | $5.7M | +$4.5M | 79.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 220,971 | +16,764 | $5.5M | +$3.5M | 8.2% |
| CITIGROUP INC | 147,363 | +126,917 | $3.7M | +$3.5M | 620.7% |
| JANE STREET GROUP, LLC | 132,100 | +119,100 | $3.3M | +$3.2M | 916.1% |
| Bank of New York Mellon Corp | 176,201 | +7,004 | $4.4M | +$2.7M | 4.1% |
| Invesco Ltd. | 155,732 | +31,098 | $3.9M | +$2.7M | 24.9% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 102,322 | +81,781 | $2.6M | +$2.4M | 398.1% |
| AMERICAN CENTURY COMPANIES INC | 93,900 | +34,905 | $2.3M | +$1.8M | 59.2% |
| WELLS FARGO & COMPANY/MN | 84,130 | +38,469 | $2.1M | +$1.7M | 84.2% |
| DIADEMA PARTNERS LP | 96,100 | +5,600 | $2.4M | +$1.5M | 6.2% |
| ADAR1 Capital Management, LLC | 81,399 | +20,199 | $2.0M | +$1.4M | 33.0% |
| ALPS ADVISORS INC | 64,592 | +32,082 | $1.6M | +$1.3M | 98.7% |
| Quantinno Capital Management LP | 61,306 | +20,976 | $1.5M | +$1.1M | 52.0% |
| Creative Planning | 64,654 | +9,344 | $1.6M | +$1.1M | 16.9% |
| DEUTSCHE BANK AG\ | 63,067 | +1,975 | $1.6M | +$978.6K | 3.2% |
| NEW YORK STATE COMMON RETIREMENT FUND | 28,234 | +19,366 | $705.9K | +$619.0K | 218.4% |
| Campbell & CO Investment Adviser LLC | 35,556 | +6,508 | $888.9K | +$604.5K | 22.4% |
| Voya Investment Management LLC | 25,991 | +14,909 | $649.8K | +$541.3K | 134.5% |
| PDT Partners, LLC | 27,368 | +12,067 | $684.2K | +$534.4K | 78.9% |
| INTECH INVESTMENT MANAGEMENT LLC | 25,198 | +11,631 | $630.0K | +$497.1K | 85.7% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 30,268 | +2,934 | $756.9K | +$489.3K | 10.7% |
| Legal & General Group Plc | 20,490 | +15,068 | $512.3K | +$459.2K | 277.9% |
| BARCLAYS PLC | 155,840 | +51,216 | $663.9K | -$360.4K | 49.0% |
| ProShare Advisors LLC | 14,367 | +1,740 | $359.2K | +$235.6K | 13.8% |
| Tower Research Capital LLC (TRC) | 9,938 | +7,413 | $248.4K | +$223.7K | 293.6% |
| China Universal Asset Management Co., Ltd. | 13,018 | +987 | $325.4K | +$207.7K | 8.2% |
| Mirae Asset Global Investments Co., Ltd. | 3,822 | +1,169 | $95.5K | +$69.6K | 44.1% |
| NISA INVESTMENT ADVISORS, LLC | 3,764 | +477 | $94.1K | +$61.9K | 14.5% |
| AlphaQuest LLC | 1,690 | +792 | $42.3K | +$33.5K | 88.2% |
| EverSource Wealth Advisors, LLC | 1,245 | +1,232 | $31.1K | +$31.0K | 9476.9% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,096,035 | +1,064,254 | $27.4K | +$27.1K | 3348.7% |
| GF FUND MANAGEMENT CO. LTD. | 1,546 | +69 | $38.6K | +$24.2K | 4.7% |
| GAMMA Investing LLC | 723 | +492 | $18.1K | +$15.8K | 213.0% |
| SRS Capital Advisors, Inc. | 564 | +559 | $14.1K | +$14.1K | 11180.0% |
| ADVISOR GROUP HOLDINGS, INC. | 474 | +469 | $11.8K | +$11.8K | 9380.0% |
| Optiver Holding B.V. | 339 | +103 | $8.5K | +$6.2K | 43.6% |
| Farther Finance Advisors, LLC | 180 | +150 | $4.5K | +$4.2K | 500.0% |
| ROTHSCHILD INVESTMENT LLC | 227 | +2 | $5.7K | +$3.5K | 0.9% |
| SBI Securities Co., Ltd. | 61 | +10 | $1.5K | +$1.0K | 19.6% |
| HRT FINANCIAL LP | 40,266 | +23,975 | $1.0K | +$847 | 147.2% |
| AMALGAMATED BANK | 1,871 | +460 | $47 | +$33 | 32.6% |
Reduced(56)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| BVF INC/IL | 5,295,893 | 0 | $132.4M | +$80.6M | 0.0% |
| Logos Global Management LP | 3,208,875 | 0 | $80.2M | +$48.8M | 0.0% |
| FRANKLIN RESOURCES INC | 2,476,665 | -535,304 | $61.9M | +$32.4M | -17.8% |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | 1,930,894 | 0 | $48.3M | +$29.4M | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,257,441 | -18,564 | $31.4M | +$18.9M | -1.4% |
| Woodline Partners LP | 1,481,930 | -735,963 | $37.0M | +$15.3M | -33.2% |
| DIMENSIONAL FUND ADVISORS LP | 958,644 | -105,905 | $24.0M | +$13.5M | -9.9% |
| NORTHERN TRUST CORP | 445,327 | -37,705 | $11.1M | +$6.4M | -7.8% |
| AMERIPRISE FINANCIAL INC | 204,629 | -942,439 | $5.1M | -$6.1M | -82.2% |
| Candriam S.C.A. | 679,484 | -570,243 | $17.0M | +$4.8M | -45.6% |
| Soleus Capital Management, L.P. | 69,874 | -550,000 | $1.7M | -$4.3M | -88.7% |
| UBS Group AG | 293,560 | -897,094 | $7.3M | -$4.3M | -75.3% |
| SILVERARC CAPITAL MANAGEMENT, LLC | 206,280 | -727,261 | $5.2M | -$4.0M | -77.9% |
| Pictet Asset Management Holding SA | 502,568 | -1,133,804 | $12.6M | -$3.4M | -69.3% |
| BNP PARIBAS ARBITRAGE, SNC | 10,362 | -289,257 | $259.1K | -$2.7M | -96.5% |
| Balyasny Asset Management LLC | 167,308 | -525,871 | $4.2M | -$2.6M | -75.9% |
| Vivo Capital, LLC | 671,843 | -834,019 | $16.8M | +$2.1M | -55.4% |
| BANK OF AMERICA CORP /DE/ | 238,914 | -563,390 | $6.0M | -$1.9M | -70.2% |
| Susquehanna Portfolio Strategies, LLC | 121,342 | 0 | $3.0M | +$1.8M | 0.0% |
| HighVista Strategies LLC | 241,489 | -195,690 | $6.0M | +$1.8M | -44.8% |
| Pier Capital, LLC | 140,101 | -384,148 | $3.5M | -$1.6M | -73.3% |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 94,883 | 0 | $2.4M | +$1.4M | 0.0% |
| MORGAN STANLEY | 665,803 | -890,084 | $16.6M | +$1.4M | -57.2% |
| VICTORY CAPITAL MANAGEMENT INC | 86,100 | -2,050 | $2.2M | +$1.3M | -2.3% |
| AQR CAPITAL MANAGEMENT LLC | 81,167 | -14 | $2.0M | +$1.2M | -0.0% |
| RHUMBLINE ADVISERS | 74,379 | -9,910 | $1.9M | +$1.0M | -11.8% |
| ALLIANCEBERNSTEIN L.P. | 62,610 | -14,050 | $1.6M | +$814.7K | -18.3% |
| PORTLAND INVESTMENT COUNSEL INC. | 50,000 | 0 | $1.3M | +$760.5K | 0.0% |
| MetLife Investment Management, LLC | 33,500 | -4,120 | $837.5K | +$469.2K | -10.9% |
| LPL Financial LLC | 56,195 | -40,480 | $1.4M | +$458.4K | -41.9% |
| Royal Bank of Canada | 6,700 | -133,043 | $167.0K | -$417.0K | -95.2% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 40,500 | -29,500 | $1.0M | +$327.2K | -42.1% |
| RENAISSANCE TECHNOLOGIES LLC | 25,067 | -65,033 | $626.7K | -$255.4K | -72.2% |
| Police & Firemen's Retirement System of New Jersey | 16,640 | 0 | $416.0K | +$253.1K | 0.0% |
| CONWAY CAPITAL MANAGEMENT, INC. | 10,000 | 0 | $250.0K | +$152.1K | 0.0% |
| SIMPLEX TRADING, LLC | 5,321 | -20,371 | $133.0K | +$132.8K | -79.3% |
| Quarry LP | 3,001 | -15,750 | $75.0K | -$108.5K | -84.0% |
| Ameritas Investment Partners, Inc. | 4,975 | 0 | $124.4K | +$75.7K | 0.0% |
| Virtus Investment Advisers, Inc. | 8,049 | -19,977 | $201.2K | -$73.2K | -71.3% |
| Russell Investments Group, Ltd. | 4,735 | -664 | $118.4K | +$65.5K | -12.3% |
| State of Wyoming | 4,676 | -599 | $116.9K | +$65.3K | -11.3% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,666 | -62 | $91.7K | +$55.2K | -1.7% |
| Sterling Capital Management LLC | 3,441 | -668 | $86.0K | +$45.8K | -16.3% |
| Federation des caisses Desjardins du Quebec | 2,000 | 0 | $50.0K | +$30.4K | 0.0% |
| Versant Capital Management, Inc | 1,178 | -245 | $29.4K | +$15.5K | -17.2% |
| Truvestments Capital LLC | 838 | 0 | $20.9K | +$12.7K | 0.0% |
| WOLFF WIESE MAGANA LLC | 600 | 0 | $15.0K | +$9.1K | 0.0% |
| PNC Financial Services Group, Inc. | 551 | -166 | $13.8K | +$6.8K | -23.1% |
| UMA Financial Services, Inc. | 391 | 0 | $9.8K | +$5.9K | 0.0% |
| Parkside Financial Bank & Trust | 135 | 0 | $3.4K | +$2.1K | 0.0% |
| True Wealth Design, LLC | 61 | 0 | $1.5K | +$927 | 0.0% |
| CWM, LLC | 6,284 | -29 | $157 | +$95 | -0.5% |
| HUNTINGTON NATIONAL BANK | 1 | 0 | $25 | +$15 | 0.0% |
| Daiwa Securities Group Inc. | 224 | 0 | $6 | +$4 | 0.0% |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | $0 | $0 | — |
| Covestor Ltd | 16 | 0 | $0 | $0 | 0.0% |
Sold Out(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Deep Track Capital, LP | 0 | -3,470,172 | $0 | -$34.0M | — |
| Affinity Asset Advisors, LLC | 0 | -500,000 | $0 | -$4.9M | — |
| HSBC HOLDINGS PLC | 0 | -35,179 | $0 | -$343.0K | — |
| ZACKS INVESTMENT MANAGEMENT | 0 | -30,803 | $0 | -$301.6K | — |
| Brooklyn Investment Group | 0 | -45,842 | $0 | -$211.8K | — |
| TWO SIGMA ADVISERS, LP | 0 | -21,100 | $0 | -$206.6K | — |
| TITLEIST ASSET MANAGEMENT, LLC | 0 | -15,000 | $0 | -$146.8K | — |
| J. Goldman & Co LP | 0 | -13,500 | $0 | -$132.2K | — |
| Sender Co & Partners, Inc. | 0 | -10,793 | $0 | -$105.7K | — |
| CI Private Wealth, LLC | 0 | -10,299 | $0 | -$100.8K | — |
| PRINCIPAL SECURITIES, INC. | 0 | -466 | $0 | -$4.6K | — |
| Point72 Europe (London) LLP | 0 | -404 | $0 | -$4.0K | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 8,508,641 | $212.7M | +1,664,687 | 24.3% |
| Paradigm Biocapital Advisors LP | 7,544,172 | $188.6M | +750,000 | 11.0% |
| JANUS HENDERSON GROUP PLC | 6,710,194 | $167.9M | +3,124,345 | 87.1% |
| BlackRock, Inc. | 5,563,260 | $139.1M | +836,866 | 17.7% |
| BVF INC/IL | 5,295,893 | $132.4M | 0 | 0.0% |
| FMR LLC | 5,023,092 | $125.6M | +4,993,670 | 16972.6% |
| VANGUARD GROUP INC | 3,561,355 | $89.0M | +364,035 | 11.4% |
| Siren, L.L.C. | 3,300,700 | $82.5M | +3,300,700 | — |
| Logos Global Management LP | 3,208,875 | $80.2M | 0 | 0.0% |
| Cormorant Asset Management, LP | 2,750,000 | $68.8M | +2,750,000 | — |
| RA CAPITAL MANAGEMENT, L.P. | 2,600,000 | $65.0M | +2,600,000 | — |
| FRANKLIN RESOURCES INC | 2,476,665 | $61.9M | -535,304 | -17.8% |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | 1,930,894 | $48.3M | 0 | 0.0% |
| STATE STREET CORP | 1,884,399 | $47.1M | +790,825 | 72.3% |
| Vestal Point Capital, LP | 1,650,000 | $41.3M | +1,650,000 | — |
| Woodline Partners LP | 1,481,930 | $37.0M | -735,963 | -33.2% |
| Polar Capital Holdings Plc | 1,380,450 | $34.5M | +1,380,450 | — |
| CITADEL ADVISORS LLC | 1,374,407 | $34.4M | +124,492 | 10.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,257,441 | $31.4M | -18,564 | -1.4% |
| Defilade Capital Management, L.P. | 1,234,634 | $30.9M | +1,234,634 | — |
New & Closed Positions this quarter
Closed Positions
12 managers exited
Top five by prior-quarter value
- Deep Track Capital, LP$34.0M
- Affinity Asset Advisors, LLC$4.9M
- HSBC HOLDINGS PLC$343.0K
- ZACKS INVESTMENT MANAGEMENT$301.6K
- Brooklyn Investment Group$211.8K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for OLMA against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.