Institutional Manager · CIK 0001224962
PERCEPTIVE ADVISORS LLC
NEW YORK, NY · File #028-10438
Latest AUM
$5.61B
Positions
116
Top-10 Concentration
47.6%
Filings
17
Sector Allocation
Filing History
View all filings →- 13F HOLDINGS REPORTQ/E Dec 2025116 pos · $5.61B
- 13F HOLDINGS REPORTQ/E Sep 202593 pos · $3.46B
- 13F HOLDINGS REPORTQ/E Jun 202585 pos · $2.70B
- 13F HOLDINGS REPORT (Amended)Q/E Jun 202587 pos · $2.83B
- 13F HOLDINGS REPORTQ/E Mar 202587 pos · $2.84B
- 13F HOLDINGS REPORTQ/E Dec 202499 pos · $3.63B
- 13F HOLDINGS REPORTQ/E Sep 2024108 pos · $4.73B
- 13F HOLDINGS REPORT (Amended)Q/E Jun 2024110 pos · $4.15B
- 13F HOLDINGS REPORTQ/E Jun 2024111 pos · $4.20B
- 13F HOLDINGS REPORT (Amended)Q/E Jun 2024112 pos · $5.72B
- 13F HOLDINGS REPORTQ/E Mar 2024112 pos · $5.76B
- 13F HOLDINGS REPORTQ/E Dec 202397 pos · $3.00B
- 13F HOLDINGS REPORT (Amended)Q/E Sep 202395 pos · $3.45B
- 13F HOLDINGS REPORTQ/E Sep 202395 pos · $3.45B
- 13F HOLDINGS REPORT (Amended)Q/E Jun 202399 pos · $3.39B
- 13F HOLDINGS REPORTQ/E Jun 202399 pos · $3.84B
- 13F HOLDINGS REPORTQ/E Mar 202396 pos · $3.56B
Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | PRAXIS PRECISION MEDICINES I | PRAX | 1,995,986 | $588.3M | 11.96% |
| 2 | CELCUITY INC | CELC | 3,160,200 | $315.2M | 6.41% |
| 3 | RHYTHM PHARMACEUTICALS INC | RYTM | 2,546,391 | $272.6M | 5.54% |
| 4 | ASCENDIS PHARMA A/S | ASND | 1,081,421 | $230.6M | 4.69% |
| 5 | APOGEE THERAPEUTICS INC | APGE | 2,330,651 | $175.9M | 3.58% |
| 6 | ROIVANT SCIENCES LTD | ROIV | 7,985,461 | $173.3M | 3.52% |
| 7 | NUVALENT INC | NUVL | 1,665,105 | $167.5M | 3.41% |
| 8 | TRAVERE THERAPEUTICS INC | TVTX | 4,278,180 | $163.5M | 3.32% |
| 9 | SPDR SERIES TRUST | 78464A870 | 1,100,000 | $134.1M | 2.73% |
| 10 | EXACT SCIENCES CORP | 30063P105 | 1,200,487 | $121.9M | 2.48% |
| 11 | PROTAGONIST THERAPEUTICS INC | PTGX | 1,350,425 | $117.9M | 2.40% |
| 12 | INHIBRX BIOSCIENCES INC | INBX | 1,452,707 | $114.8M | 2.33% |
| 13 | EDGEWISE THERAPEUTICS | EWTX | 4,457,974 | $110.6M | 2.25% |
| 14 | IMMATICS N.V | IMTX | 10,383,456 | $109.0M | 2.22% |
| 15 | SPYRE THERAPEUTICS INC | SYRE | 3,069,225 | $100.5M | 2.04% |
| 16 | AMYLYX PHARMACEUTICALS INC | AMLX | 8,284,882 | $100.1M | 2.03% |
| 17 | ARCELLX INC | ACLX | 1,466,071 | $95.6M | 1.94% |
| 18 | VIRIDIAN THERAPEUTICS INC | VRDN | 3,042,703 | $94.7M | 1.93% |
| 19 | BOSTON SCIENTIFIC CORP | BSX | 979,000 | $93.3M | 1.90% |
| 20 | AMICUS THERAPEUTICS INC | FOLD | 6,370,851 | $90.7M | 1.84% |