New Positions
37 managers initiated
Top five by reported value
Precigen Inc NASDAQ NMS - GLOBAL MARKET:PGEN
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
37 new75 added69 reduced24 exited
Total Institutional Holders
180
as of 2025-12-31
Top Holder
Patient Capital Management, LLC
$78.1M
Largest QoQ Increase
Point72 Asset Management, L.P.
+11,080,875 sh
Largest QoQ Decrease
Patient Capital Management, LLC
-7,787,382 sh
New Positions(37)
Added To(75)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 13,821,941 | +11,080,875 | $57.8M | +$48.8M | 404.3% |
| STATE STREET CORP | 10,824,860 | +6,335,033 | $45.2M | +$30.5M | 141.1% |
| BlackRock, Inc. | 15,094,359 | +2,944,404 | $63.1M | +$23.1M | 24.2% |
| FMR LLC | 4,652,179 | +4,535,517 | $19.4M | +$19.1M | 3887.7% |
| VANGUARD GROUP INC | 10,479,452 | +1,537,167 | $43.8M | +$14.4M | 17.2% |
| Diametric Capital, LP | 3,847,024 | +2,872,796 | $16.1M | +$12.9M | 294.9% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 3,601,674 | +1,559,164 | $15.1M | +$8.3M | 76.3% |
| MORGAN STANLEY | 3,193,523 | +1,211,879 | $13.3M | +$6.8M | 61.1% |
| GOLDMAN SACHS GROUP INC | 2,173,933 | +1,440,446 | $9.1M | +$6.7M | 196.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 4,462,078 | +613,340 | $18.7M | +$6.0M | 15.9% |
| Occam Crest Management LP | 3,501,739 | +804,339 | $14.6M | +$5.8M | 29.8% |
| Boxer Capital Management, LLC | 2,225,000 | +1,375,000 | $8.5M | +$5.7M | 161.8% |
| CITADEL ADVISORS LLC | 3,686,384 | +221,253 | $15.4M | +$4.0M | 6.4% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,506,755 | +246,842 | $6.3M | +$2.2M | 19.6% |
| NORTHERN TRUST CORP | 1,579,142 | +203,178 | $6.6M | +$2.1M | 14.8% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 649,974 | +380,463 | $2.7M | +$1.8M | 141.2% |
| UBS Group AG | 891,428 | +260,824 | $3.7M | +$1.7M | 41.4% |
| Voleon Capital Management LP | 464,814 | +318,150 | $1.9M | +$1.5M | 216.9% |
| JPMORGAN CHASE & CO | 914,919 | +154,524 | $3.8M | +$1.3M | 20.3% |
| Rafferty Asset Management, LLC | 374,202 | +271,478 | $1.6M | +$1.2M | 264.3% |
| Invesco Ltd. | 373,782 | +267,223 | $1.6M | +$1.2M | 250.8% |
| VICTORY CAPITAL MANAGEMENT INC | 236,632 | +219,627 | $989.1K | +$933.2K | 1291.5% |
| PRUDENTIAL FINANCIAL INC | 194,100 | +173,720 | $811.3K | +$744.3K | 852.4% |
| WELLS FARGO & COMPANY/MN | 326,352 | +132,492 | $1.4M | +$726.4K | 68.3% |
| Bank of New York Mellon Corp | 468,845 | +87,226 | $2.0M | +$704.2K | 22.9% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 172,530 | +161,947 | $721.2K | +$686.4K | 1530.3% |
| Legal & General Group Plc | 146,959 | +130,653 | $614.3K | +$560.7K | 801.3% |
| STATE OF WISCONSIN INVESTMENT BOARD | 211,904 | +106,304 | $885.8K | +$538.3K | 100.7% |
| PROFUND ADVISORS LLC | 138,407 | +114,454 | $578.5K | +$499.7K | 477.8% |
| CITIGROUP INC | 115,707 | +102,344 | $483.7K | +$439.7K | 765.9% |
| AQR CAPITAL MANAGEMENT LLC | 186,400 | +79,939 | $779.2K | +$428.9K | 75.1% |
| ALLIANCEBERNSTEIN L.P. | 206,050 | +52,530 | $861.3K | +$356.2K | 34.2% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 78,857 | +71,764 | $329.6K | +$306.3K | 1011.8% |
| CIBC Private Wealth Group, LLC | 274,712 | +17,247 | $1.1M | +$301.2K | 6.7% |
| LPL Financial LLC | 204,524 | +31,100 | $854.9K | +$284.3K | 17.9% |
| DEUTSCHE BANK AG\ | 135,809 | +47,409 | $567.7K | +$276.8K | 53.6% |
| Squarepoint Ops LLC | 79,078 | +56,138 | $330.5K | +$255.1K | 244.7% |
| ADVISOR GROUP HOLDINGS, INC. | 219,584 | +31,453 | $917.8K | +$234.7K | 16.7% |
| Atom Investors LP | 61,825 | +46,996 | $258.4K | +$209.6K | 316.9% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 105,557 | +31,295 | $443.0K | +$196.9K | 42.1% |
| MetLife Investment Management, LLC | 100,133 | +15,816 | $418.6K | +$141.2K | 18.8% |
| HighTower Advisors, LLC | 104,560 | +4,249 | $437.1K | +$107.0K | 4.2% |
| STIFEL FINANCIAL CORP | 82,657 | +6,700 | $345.5K | +$95.6K | 8.8% |
| ProShare Advisors LLC | 48,666 | +12,399 | $203.4K | +$84.1K | 34.2% |
| XTX Topco Ltd | 49,668 | +10,005 | $207.6K | +$77.1K | 25.2% |
| China Universal Asset Management Co., Ltd. | 57,656 | +5,426 | $241.0K | +$69.2K | 10.4% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 56,006 | +5,222 | $234.1K | +$67.0K | 10.3% |
| INTECH INVESTMENT MANAGEMENT LLC | 63,018 | +3,137 | $263.4K | +$66.4K | 5.2% |
| Susquehanna Portfolio Strategies, LLC | 30,482 | +11,457 | $127.4K | +$64.8K | 60.2% |
| RAYMOND JAMES FINANCIAL INC | 37,182 | +9,013 | $155.4K | +$62.7K | 32.0% |
| ENVESTNET ASSET MANAGEMENT INC | 45,892 | +4,549 | $191.8K | +$55.8K | 11.0% |
| Police & Firemen's Retirement System of New Jersey | 44,483 | +914 | $185.9K | +$42.6K | 2.1% |
| Voya Investment Management LLC | 31,748 | +3,517 | $132.7K | +$39.8K | 12.4% |
| Mirae Asset Global Investments Co., Ltd. | 17,194 | +5,674 | $71.9K | +$34.0K | 49.3% |
| MAGNOLIA CAPITAL ADVISORS LLC | 36,531 | +136 | $152.7K | +$33.0K | 0.4% |
| Summit Trail Advisors, LLC | 30,357 | +1,124 | $126.9K | +$30.7K | 3.8% |
| Miracle Mile Advisors, LLC | 21,217 | +3,000 | $88.7K | +$28.8K | 16.5% |
| Vanguard Personalized Indexing Management, LLC | 31,399 | +134 | $131.2K | +$28.4K | 0.4% |
| Flower City Capital | 21,000 | +1,000 | $87.8K | +$22.0K | 5.0% |
| XPONANCE, INC. | 14,191 | +2,496 | $59.3K | +$20.8K | 21.3% |
| Russell Investments Group, Ltd. | 12,508 | +83 | $52.3K | +$11.4K | 0.7% |
| NISA INVESTMENT ADVISORS, LLC | 3,950 | +1,435 | $16.5K | +$8.2K | 57.0% |
| GF FUND MANAGEMENT CO. LTD. | 6,952 | +541 | $29.1K | +$8.0K | 8.4% |
| Sterling Capital Management LLC | 1,733 | +720 | $7.2K | +$3.9K | 71.1% |
| Farther Finance Advisors, LLC | 754 | +714 | $3.2K | +$3.0K | 1785.0% |
| Rockefeller Capital Management L.P. | 888 | +454 | $3.7K | +$2.3K | 104.6% |
| NATIONAL BANK OF CANADA /FI/ | 568 | +84 | $2.4K | +$782 | 17.4% |
| SBI Securities Co., Ltd. | 128 | +15 | $535 | +$163 | 13.3% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 97,938 | +18,382 | $410 | +$148 | 23.1% |
| SG Americas Securities, LLC | 39,319 | +15,969 | $164 | +$87 | 68.4% |
| Daiwa Securities Group Inc. | 20,265 | +19,557 | $85 | +$83 | 2762.3% |
| PNC Financial Services Group, Inc. | 19 | +14 | $80 | +$64 | 280.0% |
| Janney Montgomery Scott LLC | 30,288 | +275 | $127 | +$28 | 0.9% |
| STONERIDGE INVESTMENT PARTNERS LLC | 16,126 | +2,307 | $67 | +$22 | 16.7% |
| AMALGAMATED BANK | 5,664 | +1,043 | $24 | +$9 | 22.6% |
Reduced(69)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 5,617,500 | -6,782,500 | $23.5M | -$17.3M | -54.7% |
| Caption Management, LLC | 1,100,000 | -3,427,500 | $4.6M | -$10.3M | -75.7% |
| Patient Capital Management, LLC | 18,673,466 | -7,787,382 | $78.1M | -$9.0M | -29.4% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,200,280 | -1,650,995 | $5.0M | -$4.4M | -57.9% |
| IRIDIAN ASSET MANAGEMENT LLC/CT | 3,600,195 | -66,751 | $15.0M | +$3.0M | -1.8% |
| Parkman Healthcare Partners LLC | 1,002,826 | -1,098,889 | $4.2M | -$2.7M | -52.3% |
| JANE STREET GROUP, LLC | 338,700 | -555,203 | $1.4M | -$1.5M | -62.1% |
| BARCLAYS PLC | 306,418 | -249,438 | $435.1K | -$1.4M | -44.9% |
| BANK OF AMERICA CORP /DE/ | 2,188,606 | -317,386 | $9.1M | +$903.7K | -12.7% |
| CI Private Wealth, LLC | 431,723 | -365,848 | $1.8M | -$819.5K | -45.9% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 846,000 | 0 | $3.5M | +$752.9K | 0.0% |
| SIMPLEX TRADING, LLC | 180,163 | -33,939 | $753.1K | +$752.4K | -15.8% |
| Royal Bank of Canada | 5,288 | -379,404 | $23.0K | -$523.0K | -98.6% |
| EAM Investors, LLC | 405,001 | -272,369 | $1.7M | -$499.2K | -40.2% |
| Lansing Street Advisors | 547,038 | 0 | $2.3M | +$486.9K | 0.0% |
| Nuveen, LLC | 528,959 | -269,848 | $2.2M | -$417.0K | -33.8% |
| Cetera Investment Advisers | 371,264 | -5,457 | $1.6M | +$312.5K | -1.4% |
| WELLINGTON MANAGEMENT GROUP LLP | 482,947 | -39,234 | $2.0M | +$300.7K | -7.5% |
| Brevan Howard Capital Management LP | 26,267 | -97,475 | $109.8K | -$297.3K | -78.8% |
| FRANKLIN RESOURCES INC | 468,038 | -199,140 | $2.0M | -$238.6K | -29.8% |
| COMMONWEALTH EQUITY SERVICES, LLC | 46,829 | -8,569 | $195.8K | +$195.6K | -15.5% |
| Creative Planning | 170,619 | -1,937 | $713.2K | +$145.5K | -1.1% |
| Mill Creek Capital Advisors, LLC | 150,000 | 0 | $627.0K | +$133.5K | 0.0% |
| RHUMBLINE ADVISERS | 197,274 | -18,495 | $824.6K | +$114.7K | -8.6% |
| BNP PARIBAS ARBITRAGE, SNC | 20,157 | -31,639 | $84.3K | -$86.2K | -61.1% |
| Tower Research Capital LLC (TRC) | 8,355 | -26,342 | $34.9K | -$79.2K | -75.9% |
| CARY STREET PARTNERS FINANCIAL LLC | 87,593 | 0 | $366.1K | +$78.0K | 0.0% |
| Alpha Advisors, LLC/VA | 20,230 | -60,690 | $84.6K | -$63.5K | -75.0% |
| AMERICAN FINANCIAL GROUP INC | 66,114 | 0 | $276.4K | +$58.8K | 0.0% |
| TWO SIGMA ADVISERS, LP | 73,100 | -4,800 | $305.6K | +$49.3K | -6.2% |
| Aptus Capital Advisors, LLC | 44,428 | 0 | $185.7K | +$39.5K | 0.0% |
| GUARDIAN WEALTH ADVISORS, LLC / NC | 44,399 | 0 | $185.6K | +$39.5K | 0.0% |
| SEI INVESTMENTS CO | 48,071 | -24,960 | $200.9K | -$39.3K | -34.2% |
| NEW YORK STATE COMMON RETIREMENT FUND | 38,038 | 0 | $159.0K | +$33.9K | 0.0% |
| Apella Capital, LLC | 28,985 | 0 | $121.2K | +$20.0K | 0.0% |
| Headlands Technologies LLC | 26,471 | -13,237 | $110.6K | -$20.0K | -33.3% |
| Inspire Investing, LLC | 110,397 | -23,829 | $461.5K | +$19.9K | -17.8% |
| Clearstead Advisors, LLC | 20,600 | 0 | $86.1K | +$18.3K | 0.0% |
| SMITH, MOORE & CO. | 20,000 | 0 | $83.6K | +$17.8K | 0.0% |
| Cerity Partners LLC | 18,534 | -261 | $77.5K | +$15.6K | -1.4% |
| Allegheny Financial Group LTD | 17,065 | 0 | $71.3K | +$15.2K | 0.0% |
| Wellington Shields & Co., LLC | 17,000 | 0 | $71.1K | +$15.1K | 0.0% |
| Intellus Advisors LLC | 15,870 | 0 | $66.3K | +$14.1K | 0.0% |
| Ameritas Investment Partners, Inc. | 13,542 | 0 | $56.6K | +$12.1K | 0.0% |
| Caitong International Asset Management Co., Ltd | 7,723 | -4,163 | $32.3K | -$6.8K | -35.0% |
| Fortis Group Advisors, LLC | 18,966 | 0 | $85.2K | +$6.6K | 0.0% |
| Geneos Wealth Management Inc. | 7,100 | 0 | $29.7K | +$6.3K | 0.0% |
| PRINCIPAL FINANCIAL GROUP INC | 10,472 | -1,191 | $43.8K | +$5.4K | -10.2% |
| Key Financial Inc | 5,000 | 0 | $20.9K | +$4.2K | 0.0% |
| EverSource Wealth Advisors, LLC | 2,951 | -108 | $12.3K | +$2.3K | -3.5% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1,626 | 0 | $6.8K | +$1.4K | 0.0% |
| ADIRONDACK TRUST CO | 1,000 | 0 | $4.2K | +$900 | 0.0% |
| IFP Advisors, Inc | 0 | 0 | $730 | +$730 | — |
| Spire Wealth Management | 800 | 0 | $3.3K | +$712 | 0.0% |
| SIGNATUREFD, LLC | 1,076 | -76 | $4.5K | +$708 | -6.6% |
| UMA Financial Services, Inc. | 758 | 0 | $3.2K | +$675 | 0.0% |
| Optiver Holding B.V. | 1,223 | -512 | $5.1K | -$596 | -29.5% |
| AdvisorNet Financial, Inc | 660 | 0 | $2.8K | +$588 | 0.0% |
| Steward Partners Investment Advisory, LLC | 600 | 0 | $2.5K | +$534 | 0.0% |
| Truvestments Capital LLC | 578 | 0 | $2.4K | +$514 | 0.0% |
| CoreCap Advisors, LLC | 500 | 0 | $2.1K | +$445 | 0.0% |
| Vermillion & White Wealth Management Group, LLC | 450 | 0 | $1.9K | +$400 | 0.0% |
| JONES FINANCIAL COMPANIES LLLP | 181 | 0 | $757 | +$122 | 0.0% |
| CWM, LLC | 45,884 | -284 | $192 | +$40 | -0.6% |
| COMERICA BANK | 64 | -10 | $268 | +$25 | -13.5% |
| Cambridge Investment Research Advisors, Inc. | 27,994 | -13,235 | $117 | -$19 | -32.1% |
| Sunbelt Securities, Inc. | 10 | 0 | $42 | +$9 | 0.0% |
| EASTERN BANK | 3 | 0 | $13 | +$3 | 0.0% |
| Hudson Bay Capital Management LP | 20,180 | 0 | $66.4K | $0 | 0.0% |
Sold Out(24)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Patient Capital Management, LLC | 18,673,466 | $78.1M | -7,787,382 | -29.4% |
| BlackRock, Inc. | 15,094,359 | $63.1M | +2,944,404 | 24.2% |
| Point72 Asset Management, L.P. | 13,821,941 | $57.8M | +11,080,875 | 404.3% |
| STATE STREET CORP | 10,824,860 | $45.2M | +6,335,033 | 141.1% |
| VANGUARD GROUP INC | 10,479,452 | $43.8M | +1,537,167 | 17.2% |
| TANG CAPITAL MANAGEMENT LLC | 5,617,500 | $23.5M | -6,782,500 | -54.7% |
| FMR LLC | 4,652,179 | $19.4M | +4,535,517 | 3887.7% |
| GEODE CAPITAL MANAGEMENT, LLC | 4,462,078 | $18.7M | +613,340 | 15.9% |
| Diametric Capital, LP | 3,847,024 | $16.1M | +2,872,796 | 294.9% |
| CITADEL ADVISORS LLC | 3,686,384 | $15.4M | +221,253 | 6.4% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 3,601,674 | $15.1M | +1,559,164 | 76.3% |
| IRIDIAN ASSET MANAGEMENT LLC/CT | 3,600,195 | $15.0M | -66,751 | -1.8% |
| Occam Crest Management LP | 3,501,739 | $14.6M | +804,339 | 29.8% |
| MORGAN STANLEY | 3,193,523 | $13.3M | +1,211,879 | 61.1% |
| SymBiosis Capital Partners, LLC | 3,000,000 | $12.5M | +3,000,000 | — |
| BANK OF AMERICA CORP /DE/ | 2,188,606 | $9.1M | -317,386 | -12.7% |
| GOLDMAN SACHS GROUP INC | 2,173,933 | $9.1M | +1,440,446 | 196.4% |
| Boxer Capital Management, LLC | 2,225,000 | $8.5M | +1,375,000 | 161.8% |
| NORTHERN TRUST CORP | 1,579,142 | $6.6M | +203,178 | 14.8% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,506,755 | $6.3M | +246,842 | 19.6% |
New & Closed Positions this quarter
Closed Positions
24 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for PGEN against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.