New Positions
30 managers initiated
Top five by reported value
Corvus Pharmaceuticals Inc NASDAQ NMS - GLOBAL MARKET:CRVS
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
30 new43 added53 reduced10 exited
Total Institutional Holders
125
as of 2025-12-31
Top Holder
ORBIMED ADVISORS LLC
$55.2M
Largest QoQ Increase
MORGAN STANLEY
+2,950,684 sh
Largest QoQ Decrease
Point72 Asset Management, L.P.
-3,579,274 sh
New Positions(30)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| BIOIMPACT CAPITAL LLC | 2,743,671 | +2,743,671 | $21.1M | +$21.1M | — |
| DCF Advisers, LLC | 729,000 | +729,000 | $5.6M | +$5.6M | — |
| MILLENNIUM MANAGEMENT LLC | 688,770 | +688,770 | $5.3M | +$5.3M | — |
| Logos Global Management LP | 500,000 | +500,000 | $3.9M | +$3.9M | — |
| ADAR1 Capital Management, LLC | 465,875 | +465,875 | $3.6M | +$3.6M | — |
| MARSHALL WACE, LLP | 216,248 | +216,248 | $1.7M | +$1.7M | — |
| FRED ALGER MANAGEMENT, LLC | 144,381 | +144,381 | $1.1M | +$1.1M | — |
| Qube Research & Technologies Ltd | 114,500 | +114,500 | $881.6K | +$881.6K | — |
| Squarepoint Ops LLC | 104,820 | +104,820 | $807.1K | +$807.1K | — |
| Rafferty Asset Management, LLC | 99,724 | +99,724 | $767.9K | +$767.9K | — |
| ExodusPoint Capital Management, LP | 86,720 | +86,720 | $667.7K | +$667.7K | — |
| ALPS ADVISORS INC | 61,318 | +61,318 | $472.1K | +$472.1K | — |
| PROFUND ADVISORS LLC | 37,063 | +37,063 | $285.4K | +$285.4K | — |
| AlphaQuest LLC | 35,972 | +35,972 | $277.0K | +$277.0K | — |
| Connor, Clark & Lunn Investment Management Ltd. | 28,117 | +28,117 | $216.5K | +$216.5K | — |
| Voya Investment Management LLC | 27,661 | +27,661 | $213.0K | +$213.0K | — |
| GROUP ONE TRADING, L.P. | 26,667 | +26,667 | $205.3K | +$205.3K | — |
| DRW Securities, LLC | 23,384 | +23,384 | $180.1K | +$180.1K | — |
| Verition Fund Management LLC | 21,382 | +21,382 | $164.6K | +$164.6K | — |
| Graham Capital Management, L.P. | 19,274 | +19,274 | $148.4K | +$148.4K | — |
| FOX RUN MANAGEMENT, L.L.C. | 11,220 | +11,220 | $86.4K | +$86.4K | — |
| CAPTRUST FINANCIAL ADVISORS | 11,051 | +11,051 | $85.1K | +$85.1K | — |
| Leonteq Securities AG | 20,000 | +20,000 | $64.4K | +$64.4K | — |
| Caitong International Asset Management Co., Ltd | 1,523 | +1,523 | $11.7K | +$11.7K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 725 | +725 | $5.6K | +$5.6K | — |
| Farther Finance Advisors, LLC | 323 | +323 | $2.5K | +$2.5K | — |
| Clearstead Advisors, LLC | 203 | +203 | $1.6K | +$1.6K | — |
| SageView Advisory Group, LLC | 30 | +30 | $231 | +$231 | — |
| SG Americas Securities, LLC | 20,021 | +20,021 | $154 | +$154 | — |
| Allworth Financial LP | 17 | +17 | $131 | +$131 | — |
Added To(43)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MORGAN STANLEY | 3,567,908 | +2,950,684 | $27.5M | +$22.9M | 478.1% |
| STATE STREET CORP | 2,788,223 | +1,781,904 | $21.5M | +$14.1M | 177.1% |
| VANGUARD GROUP INC | 3,873,482 | +401,557 | $29.8M | +$4.2M | 11.6% |
| BlackRock, Inc. | 5,056,361 | +345,919 | $38.9M | +$4.2M | 7.3% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 666,054 | +472,054 | $5.1M | +$3.7M | 243.3% |
| JANE STREET GROUP, LLC | 432,697 | +364,631 | $3.3M | +$2.8M | 535.7% |
| CITADEL ADVISORS LLC | 476,982 | +319,216 | $3.7M | +$2.5M | 202.3% |
| Caption Management, LLC | 180,225 | +158,398 | $1.4M | +$1.2M | 725.7% |
| WELLINGTON MANAGEMENT GROUP LLP | 314,683 | +134,508 | $2.4M | +$1.1M | 74.7% |
| GOLDMAN SACHS GROUP INC | 553,327 | +107,657 | $4.3M | +$976.0K | 24.1% |
| BARCLAYS PLC | 343,526 | +34,374 | $1.4M | -$904.3K | 11.1% |
| BANK OF AMERICA CORP /DE/ | 236,495 | +84,529 | $1.8M | +$701.0K | 55.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,473,026 | +16,498 | $11.3M | +$608.2K | 1.1% |
| UBS Group AG | 212,006 | +49,932 | $1.6M | +$438.0K | 30.8% |
| D. E. Shaw & Co., Inc. | 64,915 | +39,340 | $499.8K | +$311.4K | 153.8% |
| WELLS FARGO & COMPANY/MN | 62,623 | +26,228 | $482.2K | +$214.0K | 72.1% |
| NEOS Investment Management LLC | 80,893 | +21,691 | $622.9K | +$186.6K | 36.6% |
| TEMA ETFS LLC | 79,698 | +20,496 | $613.7K | +$177.4K | 34.6% |
| ADVISOR GROUP HOLDINGS, INC. | 67,993 | +1 | $523.5K | +$133.3K | 0.0% |
| Creative Planning | 39,178 | +13,879 | $301.7K | +$115.2K | 54.9% |
| CITIGROUP INC | 14,858 | +10,910 | $114.4K | +$85.3K | 276.3% |
| INTECH INVESTMENT MANAGEMENT LLC | 35,973 | +9,812 | $277.0K | +$84.2K | 37.5% |
| Bank of New York Mellon Corp | 131,628 | +5,100 | $1.0M | +$81.0K | 4.0% |
| Invesco Ltd. | 43,583 | +4,910 | $335.6K | +$50.6K | 12.7% |
| Virtus Investment Advisers, Inc. | 31,783 | +4,946 | $244.7K | +$46.9K | 18.4% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 32,409 | +4,884 | $248.3K | +$45.5K | 17.7% |
| China Universal Asset Management Co., Ltd. | 18,169 | +5,108 | $139.9K | +$43.6K | 39.1% |
| Sowell Financial Services LLC | 17,000 | +5,000 | $130.9K | +$42.5K | 41.7% |
| DIADEMA PARTNERS LP | 53,100 | +3,100 | $408.9K | +$40.4K | 6.2% |
| Truvestments Capital LLC | 10,257 | +4,744 | $79.0K | +$38.3K | 86.0% |
| DEUTSCHE BANK AG\ | 56,039 | +2,400 | $431.5K | +$36.2K | 4.5% |
| Palumbo Wealth Management LLC | 26,255 | +2,641 | $202.2K | +$28.1K | 11.2% |
| SHELTON WEALTH MANAGEMENT, LLC | 15,638 | +1,896 | $120.4K | +$19.1K | 13.8% |
| Ancora Advisors, LLC | 47,667 | +377 | $367.0K | +$18.5K | 0.8% |
| ProShare Advisors LLC | 13,764 | +979 | $106.0K | +$11.8K | 7.7% |
| FMR LLC | 2,291 | +819 | $17.6K | +$6.8K | 55.6% |
| Mirae Asset Global Investments Co., Ltd. | 3,629 | +748 | $27.9K | +$6.7K | 26.0% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,524 | +254 | $27.1K | +$3.0K | 7.8% |
| Sterling Capital Management LLC | 392 | +248 | $3.0K | +$2.0K | 172.2% |
| GAMMA Investing LLC | 143 | +49 | $1.1K | +$408 | 52.1% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 34,105 | +1,696 | $263 | +$24 | 5.2% |
| CWM, LLC | 205 | +148 | $2 | +$2 | 259.6% |
| AMALGAMATED BANK | 1,799 | +10 | $14 | +$1 | 0.6% |
Reduced(53)
Sold Out(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| STEMPOINT CAPITAL LP | 0 | -96,439 | $0 | -$710.8K | — |
| HSBC HOLDINGS PLC | 0 | -82,387 | $0 | -$586.6K | — |
| Jain Global LLC | 0 | -27,618 | $0 | -$203.5K | — |
| Masso Torrence Wealth Management Inc. | 0 | -17,000 | $0 | -$125.3K | — |
| Brevan Howard Capital Management LP | 0 | -15,300 | $0 | -$112.8K | — |
| Trexquant Investment LP | 0 | -12,226 | $0 | -$90.1K | — |
| PKS Advisory Services, LLC | 0 | -10,500 | $0 | -$77.4K | — |
| TORONTO DOMINION BANK | 0 | -5,700 | $0 | -$42.0K | — |
| Quarry LP | 0 | -3,653 | $0 | -$26.9K | — |
| Aquatic Capital Management LLC | 0 | -55 | $0 | -$405 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 7,165,006 | $55.2M | 0 | 0.0% |
| BlackRock, Inc. | 5,056,361 | $38.9M | +345,919 | 7.3% |
| VANGUARD GROUP INC | 3,873,482 | $29.8M | +401,557 | 11.6% |
| MORGAN STANLEY | 3,567,908 | $27.5M | +2,950,684 | 478.1% |
| ADAMS STREET PARTNERS LLC | 3,275,616 | $25.2M | 0 | 0.0% |
| Point72 Asset Management, L.P. | 2,875,000 | $22.1M | -3,579,274 | -55.5% |
| STATE STREET CORP | 2,788,223 | $21.5M | +1,781,904 | 177.1% |
| BIOIMPACT CAPITAL LLC | 2,743,671 | $21.1M | +2,743,671 | — |
| Vivo Capital, LLC | 2,234,566 | $17.2M | 0 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,473,026 | $11.3M | +16,498 | 1.1% |
| Foresite Capital Management VI LLC | 1,381,233 | $10.6M | -350,000 | -20.2% |
| DCF Advisers, LLC | 729,000 | $5.6M | +729,000 | — |
| PERCEPTIVE ADVISORS LLC | 692,441 | $5.3M | -746,154 | -51.9% |
| MILLENNIUM MANAGEMENT LLC | 688,770 | $5.3M | +688,770 | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 666,054 | $5.1M | +472,054 | 243.3% |
| GOLDMAN SACHS GROUP INC | 553,327 | $4.3M | +107,657 | 24.1% |
| Logos Global Management LP | 500,000 | $3.9M | +500,000 | — |
| CITADEL ADVISORS LLC | 476,982 | $3.7M | +319,216 | 202.3% |
| ADAR1 Capital Management, LLC | 465,875 | $3.6M | +465,875 | — |
| RTW INVESTMENTS, LP | 447,607 | $3.4M | -2,231,872 | -83.3% |
New & Closed Positions this quarter
Closed Positions
10 managers exited
Top five by prior-quarter value
- STEMPOINT CAPITAL LP$710.8K
- HSBC HOLDINGS PLC$586.6K
- Jain Global LLC$203.5K
- Masso Torrence Wealth Management Inc.$125.3K
- Brevan Howard Capital Management LP$112.8K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for CRVS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.