New Positions
28 managers initiated
Top five by reported value
Alto Neuroscience Inc NEW YORK STOCK EXCHANGE, INC.:ANRO
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
28 new28 added41 reduced10 exited
Total Institutional Holders
97
as of 2025-12-31
Top Holder
Alpha Wave Global, LP
$66.0M
Largest QoQ Increase
COMMODORE CAPITAL LP
+1,823,196 sh
Largest QoQ Decrease
MARSHALL WACE, LLP
-632,116 sh
New Positions(28)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| COMMODORE CAPITAL LP | 1,823,196 | +1,823,196 | $32.5M | +$32.5M | — |
| Vivo Capital, LLC | 1,035,551 | +1,035,551 | $18.4M | +$18.4M | — |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 336,762 | +336,762 | $6.0M | +$6.0M | — |
| Spruce Street Capital LP | 222,844 | +222,844 | $4.0M | +$4.0M | — |
| D. E. Shaw & Co., Inc. | 124,795 | +124,795 | $2.2M | +$2.2M | — |
| Qube Research & Technologies Ltd | 112,792 | +112,792 | $2.0M | +$2.0M | — |
| WELLINGTON MANAGEMENT GROUP LLP | 69,016 | +69,016 | $1.2M | +$1.2M | — |
| 683 Capital Management, LLC | 64,782 | +64,782 | $1.2M | +$1.2M | — |
| AdvisorShares Investments LLC | 44,077 | +44,077 | $784.6K | +$784.6K | — |
| Hudson Bay Capital Management LP | 34,789 | +34,789 | $619.2K | +$619.2K | — |
| DIMENSIONAL FUND ADVISORS LP | 31,176 | +31,176 | $554.9K | +$554.9K | — |
| Artia Global Partners LP | 29,192 | +29,192 | $519.6K | +$519.6K | — |
| ALPS ADVISORS INC | 25,505 | +25,505 | $454.0K | +$454.0K | — |
| ExodusPoint Capital Management, LP | 18,786 | +18,786 | $334.4K | +$334.4K | — |
| CITIGROUP INC | 12,566 | +12,566 | $223.7K | +$223.7K | — |
| OMERS ADMINISTRATION Corp | 12,400 | +12,400 | $220.7K | +$220.7K | — |
| Balyasny Asset Management LLC | 11,120 | +11,120 | $197.9K | +$197.9K | — |
| AMERICAN CENTURY COMPANIES INC | 10,360 | +10,360 | $184.4K | +$184.4K | — |
| AlphaQuest LLC | 3,821 | +3,821 | $68.0K | +$68.0K | — |
| Torren Management, LLC | 3,484 | +3,484 | $62.0K | +$62.0K | — |
| SIGNATUREFD, LLC | 1,065 | +1,065 | $19.0K | +$19.0K | — |
| WELLS FARGO & COMPANY/MN | 765 | +765 | $13.6K | +$13.6K | — |
| Global Retirement Partners, LLC | 150 | +150 | $2.7K | +$2.7K | — |
| JPMORGAN CHASE & CO | 146 | +146 | $2.6K | +$2.6K | — |
| US BANCORP \DE\ | 113 | +113 | $2.0K | +$2.0K | — |
| Cornerstone Financial Management LLC | 69 | +69 | $1.2K | +$1.2K | — |
| JONES FINANCIAL COMPANIES LLLP | 33 | +33 | $587 | +$587 | — |
| Farther Finance Advisors, LLC | 31 | +31 | $552 | +$552 | — |
Added To(28)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Vestal Point Capital, LP | 2,485,000 | +1,535,000 | $44.2M | +$40.4M | 161.6% |
| PERCEPTIVE ADVISORS LLC | 1,784,393 | +1,629,027 | $31.8M | +$31.1M | 1048.5% |
| Point72 Asset Management, L.P. | 1,606,954 | +274,517 | $28.6M | +$23.2M | 20.6% |
| VANGUARD GROUP INC | 1,365,847 | +260,440 | $24.3M | +$19.9M | 23.6% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 212,672 | +211,222 | $10.7M | +$10.7M | 14567.0% |
| MILLENNIUM MANAGEMENT LLC | 629,985 | +314,227 | $11.2M | +$9.9M | 99.5% |
| BlackRock, Inc. | 607,874 | +239,995 | $10.8M | +$9.3M | 65.2% |
| Ikarian Capital, LLC | 515,000 | +405,000 | $9.2M | +$8.7M | 368.2% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 497,156 | +341,480 | $8.8M | +$8.2M | 219.3% |
| NORTHERN TRUST CORP | 474,373 | +13,088 | $8.4M | +$6.6M | 2.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 287,435 | +49,535 | $5.1M | +$4.2M | 20.8% |
| JANE STREET GROUP, LLC | 241,741 | +193,375 | $4.3M | +$4.1M | 399.8% |
| GOLDMAN SACHS GROUP INC | 156,319 | +66,068 | $2.8M | +$2.4M | 73.2% |
| BOOTHBAY FUND MANAGEMENT, LLC | 139,304 | +106,832 | $2.5M | +$2.3M | 329.0% |
| TWO SIGMA ADVISERS, LP | 160,100 | +10,200 | $2.8M | +$2.2M | 6.8% |
| TWO SIGMA INVESTMENTS, LP | 140,317 | +23,738 | $2.5M | +$2.0M | 20.4% |
| STATE STREET CORP | 130,665 | +27,480 | $2.3M | +$1.9M | 26.6% |
| RENAISSANCE TECHNOLOGIES LLC | 97,399 | +21,627 | $1.7M | +$1.4M | 28.5% |
| IEQ CAPITAL, LLC | 75,294 | +12,315 | $1.3M | +$1.1M | 19.6% |
| MORGAN STANLEY | 65,581 | +4,545 | $1.2M | +$922.0K | 7.4% |
| Allianz Asset Management GmbH | 43,000 | +6,000 | $765.4K | +$616.7K | 16.2% |
| BNP PARIBAS ARBITRAGE, SNC | 33,235 | +32,721 | $591.6K | +$589.5K | 6365.9% |
| AlphaCore Capital LLC | 20,000 | +10,000 | $356.0K | +$315.8K | 100.0% |
| XTX Topco Ltd | 20,824 | +5,078 | $370.7K | +$307.4K | 32.2% |
| BANK OF AMERICA CORP /DE/ | 11,092 | +10,968 | $197.4K | +$196.9K | 8845.2% |
| BANK OF MONTREAL /CAN/ | 11,355 | +13 | $202.1K | +$156.5K | 0.1% |
| ACADIAN ASSET MANAGEMENT LLC | 57,546 | +43,023 | $1.0K | +$962 | 296.2% |
| SBI Securities Co., Ltd. | 12 | +9 | $214 | +$202 | 300.0% |
Reduced(41)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Alpha Wave Global, LP | 3,707,757 | 0 | $66.0M | +$51.1M | 0.0% |
| ARMISTICE CAPITAL, LLC | 1,536,000 | -100,000 | $27.3M | +$20.8M | -6.1% |
| FRANKLIN RESOURCES INC | 1,119,578 | -43,030 | $19.9M | +$15.3M | -3.7% |
| 72 Investment Holdings, LLC | 667,778 | 0 | $11.9M | +$9.2M | 0.0% |
| ALKEON CAPITAL MANAGEMENT LLC | 477,101 | 0 | $8.5M | +$6.6M | 0.0% |
| Integral Health Asset Management, LLC | 375,000 | -25,000 | $6.7M | +$5.1M | -6.3% |
| Peapod Lane Capital LLC | 253,992 | -27,971 | $4.5M | +$3.4M | -9.9% |
| AWM Investment Company, Inc. | 225,000 | -55,483 | $4.0M | +$2.9M | -19.8% |
| ORBIMED ADVISORS LLC | 125,000 | -125,000 | $2.2M | +$1.2M | -50.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 77,653 | 0 | $1.4M | +$1.1M | 0.0% |
| STIFEL FINANCIAL CORP | 87,164 | -34,836 | $1.6M | +$1.1M | -28.6% |
| Almitas Capital LLC | 78,520 | -116,625 | $1.4M | +$613.2K | -59.8% |
| Quantinno Capital Management LP | 35,579 | 0 | $633.3K | +$490.3K | 0.0% |
| BROWN ADVISORY INC | 25,000 | 0 | $445.0K | +$344.5K | 0.0% |
| Citizens Financial Group Inc/RI | 28,190 | -11,810 | $501.8K | +$341.0K | -29.5% |
| CITADEL ADVISORS LLC | 29,773 | -20,579 | $530.0K | +$327.5K | -40.9% |
| SCS Capital Management LLC | 33,389 | -33,388 | $594.3K | +$325.9K | -50.0% |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO | 22,175 | 0 | $394.7K | +$305.6K | 0.0% |
| UBS Group AG | 18,489 | -120,542 | $329.1K | -$229.8K | -86.7% |
| Vanguard Personalized Indexing Management, LLC | 16,485 | -560 | $293.4K | +$224.9K | -3.3% |
| AMERIPRISE FINANCIAL INC | 13,487 | 0 | $240.1K | +$185.9K | 0.0% |
| MARSHALL WACE, LLP | 193,109 | -632,116 | $3.4M | +$119.9K | -76.6% |
| FMR LLC | 6,374 | -1,302 | $113.5K | +$82.6K | -17.0% |
| ROTHSCHILD INVESTMENT LLC | 2,885 | 0 | $51.4K | +$39.8K | 0.0% |
| Royal Bank of Canada | 34 | -12,841 | $1.0K | -$26.0K | -99.7% |
| Tower Research Capital LLC (TRC) | 1,987 | -403 | $35.4K | +$25.8K | -16.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 17,064 | -133,357 | $303.7K | -$21.2K | -88.7% |
| WHITTIER TRUST CO OF NEVADA INC | 2,482 | 0 | $37.4K | +$20.3K | 0.0% |
| PNC Financial Services Group, Inc. | 1,307 | -159 | $23.3K | +$17.4K | -10.8% |
| GROUP ONE TRADING, L.P. | 1,413 | -1,245 | $25.2K | +$14.5K | -46.8% |
| EverSource Wealth Advisors, LLC | 661 | -64 | $11.8K | +$8.9K | -8.8% |
| Fortitude Family Office, LLC | 511 | 0 | $9.1K | +$7.0K | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 338 | 0 | $6.0K | +$4.7K | 0.0% |
| Russell Investments Group, Ltd. | 306 | 0 | $5.4K | +$4.2K | 0.0% |
| North Star Investment Management Corp. | 174 | 0 | $3.1K | +$2.4K | 0.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 30,228 | -29,200 | $539 | +$300 | -49.1% |
| Optiver Holding B.V. | 20 | 0 | $356 | +$276 | 0.0% |
| FEDERATED HERMES, INC. | 770 | -2,577 | $13.7K | +$251 | -77.0% |
| BARCLAYS PLC | 1 | -41 | $2 | -$167 | -97.6% |
| SRS Capital Advisors, Inc. | 5 | -37 | $89 | -$80 | -88.1% |
| CWM, LLC | 154 | -770 | $3 | -$1 | -83.3% |
Sold Out(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| WETHERBY ASSET MANAGEMENT INC | 0 | -84,162 | $0 | -$338.3K | — |
| AQR CAPITAL MANAGEMENT LLC | 0 | -30,412 | $0 | -$122.3K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -12,200 | $0 | -$117.6K | — |
| Squarepoint Ops LLC | 0 | -22,816 | $0 | -$91.7K | — |
| Bowie Capital Management, LLC | 0 | -19,484 | $0 | -$78.3K | — |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | -11,401 | $0 | -$45.8K | — |
| Advisory Services Network, LLC | 0 | -802 | $0 | -$3.2K | — |
| True Wealth Design, LLC | 0 | -126 | $0 | -$507 | — |
| ADVISOR GROUP HOLDINGS, INC. | 0 | -47 | $0 | -$189 | — |
| Cloud Capital Management, LLC | 0 | -8 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Alpha Wave Global, LP | 3,707,757 | $66.0M | 0 | 0.0% |
| Vestal Point Capital, LP | 2,485,000 | $44.2M | +1,535,000 | 161.6% |
| COMMODORE CAPITAL LP | 1,823,196 | $32.5M | +1,823,196 | — |
| PERCEPTIVE ADVISORS LLC | 1,784,393 | $31.8M | +1,629,027 | 1048.5% |
| Point72 Asset Management, L.P. | 1,606,954 | $28.6M | +274,517 | 20.6% |
| ARMISTICE CAPITAL, LLC | 1,536,000 | $27.3M | -100,000 | -6.1% |
| VANGUARD GROUP INC | 1,365,847 | $24.3M | +260,440 | 23.6% |
| FRANKLIN RESOURCES INC | 1,119,578 | $19.9M | -43,030 | -3.7% |
| Vivo Capital, LLC | 1,035,551 | $18.4M | +1,035,551 | — |
| 72 Investment Holdings, LLC | 667,778 | $11.9M | 0 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 629,985 | $11.2M | +314,227 | 99.5% |
| BlackRock, Inc. | 607,874 | $10.8M | +239,995 | 65.2% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 212,672 | $10.7M | +211,222 | 14567.0% |
| Ikarian Capital, LLC | 515,000 | $9.2M | +405,000 | 368.2% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 497,156 | $8.8M | +341,480 | 219.3% |
| ALKEON CAPITAL MANAGEMENT LLC | 477,101 | $8.5M | 0 | 0.0% |
| NORTHERN TRUST CORP | 474,373 | $8.4M | +13,088 | 2.8% |
| Integral Health Asset Management, LLC | 375,000 | $6.7M | -25,000 | -6.3% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 336,762 | $6.0M | +336,762 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 287,435 | $5.1M | +49,535 | 20.8% |
New & Closed Positions this quarter
Closed Positions
10 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ANRO against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.