Institutional Manager · CIK 0002050194
Spruce Street Capital LP
NEW YORK, NY · File #028-26325
Latest AUM
$302.7M
Positions
27
Top-10 Concentration
70.8%
Filings
1
Sector Allocation
Filing History
View all filings →Top 20 Holdings — Dec 2025
| # | Issuer | Ticker | Shares | Value | % of Portfolio |
|---|---|---|---|---|---|
| 1 | CIDARA THERAPEUTICS INC | 171757206 | 232,269 | $51.3M | 16.95% |
| 2 | RELAY THERAPEUTICS INC | RLAY | 2,984,125 | $25.2M | 8.34% |
| 3 | LB PHARMACEUTICALS INC | LBRX | 1,005,593 | $22.4M | 7.40% |
| 4 | RELMADA THERAPEUTICS INC | RLMD | 4,086,181 | $19.7M | 6.52% |
| 5 | VAXCYTE INC | PCVX | 400,360 | $18.5M | 6.10% |
| 6 | KINIKSA PHARMACEUTICALS INTL | G52694109 | 434,982 | $17.9M | 5.93% |
| 7 | EYEPOINT INC | EYPT | 981,543 | $17.9M | 5.93% |
| 8 | SAVARA INC | SVRA | 2,411,093 | $14.5M | 4.80% |
| 9 | ERASCA INC | ERAS | 3,889,632 | $14.5M | 4.78% |
| 10 | DIANTHUS THERAPEUTICS INC | DNTH | 297,437 | $12.3M | 4.05% |
| 11 | SURROZEN INC | SRZNW | 432,040 | $9.8M | 3.23% |
| 12 | OCULAR THERAPEUTIX INC | OCUL | 783,999 | $9.5M | 3.14% |
| 13 | SAB BIOTHERAPEUTICS INC | SABSW | 2,198,502 | $8.2M | 2.72% |
| 14 | INHIBIKASE THERAPEUTICS INC | IKT | 3,581,603 | $7.3M | 2.43% |
| 15 | ENLIVEN THERAPEUTICS INC | ELVN | 446,084 | $6.9M | 2.27% |
| 16 | MINERVA NEUROSCIENCES INC | NERV | 1,655,500 | $6.7M | 2.20% |
| 17 | ABIVAX SA | AAVXF | 49,119 | $6.6M | 2.19% |
| 18 | CYBIN INC | HELP | 770,000 | $6.3M | 2.08% |
| 19 | KALVISTA PHARMACEUTICALS INC | KALV | 387,968 | $6.3M | 2.07% |
| 20 | ENANTA PHARMACEUTICALS INC | ENTA | 389,687 | $6.1M | 2.03% |