New Positions
23 managers initiated
Top five by reported value
Aldeyra Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:ALDX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
23 new39 added74 reduced17 exited
Total Institutional Holders
136
as of 2025-12-31
Top Holder
Knoll Capital Management, LLC
$28.4M
Largest QoQ Increase
683 Capital Management, LLC
+710,000 sh
Largest QoQ Decrease
PERCEPTIVE ADVISORS LLC
-1,036,679 sh
New Positions(23)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| 1492 Capital Management LLC | 223,317 | +223,317 | $1.2M | +$1.2M | — |
| Point72 Asset Management, L.P. | 94,094 | +94,094 | $487.4K | +$487.4K | — |
| Qube Research & Technologies Ltd | 84,928 | +84,928 | $439.9K | +$439.9K | — |
| ACT CAPITAL MANAGEMENT, LLC | 41,000 | +41,000 | $212.4K | +$212.4K | — |
| CANADA PENSION PLAN INVESTMENT BOARD | 35,500 | +35,500 | $183.9K | +$183.9K | — |
| Caption Management, LLC | 35,000 | +35,000 | $181.3K | +$181.3K | — |
| AlphaCentric Advisors LLC | 34,912 | +34,912 | $180.8K | +$180.8K | — |
| AXQ CAPITAL, LP | 26,810 | +26,810 | $138.9K | +$138.9K | — |
| Jump Financial, LLC | 24,480 | +24,480 | $126.8K | +$126.8K | — |
| Connor, Clark & Lunn Investment Management Ltd. | 23,858 | +23,858 | $123.6K | +$123.6K | — |
| FOX RUN MANAGEMENT, L.L.C. | 20,983 | +20,983 | $108.7K | +$108.7K | — |
| TUDOR INVESTMENT CORP ET AL | 19,000 | +19,000 | $98.4K | +$98.4K | — |
| Walleye Capital LLC | 18,595 | +18,595 | $96.3K | +$96.3K | — |
| JONES FINANCIAL COMPANIES LLLP | 15,000 | +15,000 | $77.7K | +$77.7K | — |
| U.S. Capital Wealth Advisors, LLC | 14,805 | +14,805 | $76.7K | +$76.7K | — |
| Global Retirement Partners, LLC | 10,000 | +10,000 | $51.8K | +$51.8K | — |
| INSPIRION WEALTH ADVISORS, LLC | 10,000 | +10,000 | $51.8K | +$51.8K | — |
| IFP Advisors, Inc | 2,870 | +2,870 | $14.9K | +$14.9K | — |
| Allworth Financial LP | 1,258 | +1,258 | $6.5K | +$6.5K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 892 | +892 | $4.6K | +$4.6K | — |
| MAI Capital Management | 29 | +29 | $151 | +$151 | — |
| SJS Investment Consulting Inc. | 14 | +14 | $73 | +$73 | — |
| SG Americas Securities, LLC | 12,000 | +12,000 | $62 | +$62 | — |
Added To(39)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| 683 Capital Management, LLC | 1,530,000 | +710,000 | $7.9M | +$3.6M | 86.6% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,850,000 | +518,209 | $9.6M | +$2.6M | 38.9% |
| BNP PARIBAS ARBITRAGE, SNC | 263,407 | +252,797 | $1.4M | +$1.3M | 2382.6% |
| D. E. Shaw & Co., Inc. | 1,601,324 | +221,481 | $8.3M | +$1.1M | 16.1% |
| RENAISSANCE TECHNOLOGIES LLC | 350,000 | +152,700 | $1.8M | +$783.1K | 77.4% |
| KENNEDY CAPITAL MANAGEMENT LLC | 1,255,838 | +143,625 | $6.5M | +$699.5K | 12.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 373,707 | +134,324 | $1.9M | +$686.2K | 56.1% |
| GOLDMAN SACHS GROUP INC | 305,706 | +122,763 | $1.6M | +$628.6K | 67.1% |
| JANE STREET GROUP, LLC | 383,352 | +97,634 | $2.0M | +$494.3K | 34.2% |
| VANGUARD GROUP INC | 3,698,682 | +106,813 | $19.2M | +$409.6K | 3.0% |
| ExodusPoint Capital Management, LP | 92,390 | +77,439 | $478.6K | +$400.5K | 518.0% |
| SIMPLEX TRADING, LLC | 39,755 | +10,579 | $205.9K | +$205.8K | 36.3% |
| Graham Capital Management, L.P. | 76,365 | +30,443 | $395.6K | +$155.9K | 66.3% |
| Invesco Ltd. | 163,087 | +29,382 | $844.8K | +$146.9K | 22.0% |
| STATE OF WISCONSIN INVESTMENT BOARD | 81,366 | +20,472 | $421.5K | +$103.6K | 33.6% |
| BANK OF AMERICA CORP /DE/ | 410,028 | +19,950 | $2.1M | +$87.7K | 5.1% |
| BlackRock, Inc. | 3,850,103 | +45,183 | $19.9M | +$81.8K | 1.2% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 968,751 | +21,200 | $5.0M | +$71.9K | 2.2% |
| TWO SIGMA INVESTMENTS, LP | 287,364 | +14,310 | $1.5M | +$63.2K | 5.2% |
| INTECH INVESTMENT MANAGEMENT LLC | 33,328 | +12,117 | $172.6K | +$61.9K | 57.1% |
| MetLife Investment Management, LLC | 29,531 | +11,134 | $153.0K | +$56.9K | 60.5% |
| XTX Topco Ltd | 42,227 | +7,761 | $218.7K | +$38.8K | 22.5% |
| BARCLAYS PLC | 95,648 | +19,004 | $366.3K | -$33.7K | 24.8% |
| Capital Advisors Wealth Management, LLC | 15,800 | +5,000 | $81.8K | +$25.5K | 46.3% |
| WELLS FARGO & COMPANY/MN | 369,169 | +7,700 | $1.9M | +$25.4K | 2.1% |
| CITADEL ADVISORS LLC | 352,900 | +7,446 | $1.8M | +$24.8K | 2.1% |
| Federation des caisses Desjardins du Quebec | 12,187 | +2,500 | $63.1K | +$12.6K | 25.8% |
| Russell Investments Group, Ltd. | 114,126 | +3,024 | $591.2K | +$11.2K | 2.7% |
| Activest Wealth Management | 4,000 | +2,000 | $20.7K | +$10.3K | 100.0% |
| Tower Research Capital LLC (TRC) | 5,005 | +1,383 | $25.9K | +$7.0K | 38.2% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 152,787 | +2,309 | $791.4K | +$5.9K | 1.5% |
| FMR LLC | 6,965 | +366 | $36.1K | +$1.6K | 5.5% |
| Regal Investment Advisors LLC | 13,565 | +398 | $70.3K | +$1.5K | 3.0% |
| DEUTSCHE BANK AG\ | 317,335 | +2,607 | $1.6M | +$915 | 0.8% |
| Sterling Capital Management LLC | 984 | +180 | $5.1K | +$900 | 22.4% |
| ACADIAN ASSET MANAGEMENT LLC | 979,521 | +143,710 | $5.1K | +$711 | 17.2% |
| AMERICAN CENTURY COMPANIES INC | 32,460 | +177 | $168.1K | -$374 | 0.5% |
| Farther Finance Advisors, LLC | 3,955 | +49 | $20.5K | +$97 | 1.3% |
| AMALGAMATED BANK | 1,705 | +134 | $9 | +$1 | 8.5% |
Reduced(74)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 4,185,632 | -1,036,679 | $21.7M | -$5.6M | -19.9% |
| MORGAN STANLEY | 657,032 | -426,287 | $3.4M | -$2.3M | -39.4% |
| ARDSLEY ADVISORY PARTNERS LP | 1,500,000 | -400,000 | $7.8M | -$2.1M | -21.1% |
| AQR CAPITAL MANAGEMENT LLC | 1,226,922 | -278,438 | $6.4M | -$1.5M | -18.5% |
| MILLENNIUM MANAGEMENT LLC | 44,059 | -177,106 | $228.2K | -$926.3K | -80.1% |
| UBS Group AG | 95,677 | -105,062 | $495.6K | -$552.3K | -52.3% |
| Royal Bank of Canada | 2,753 | -120,823 | $15.0K | -$464.0K | -97.8% |
| TWO SIGMA ADVISERS, LP | 121,900 | -62,200 | $631.4K | -$329.6K | -33.8% |
| SRS Capital Advisors, Inc. | 7 | -51,352 | $36 | -$268.1K | -100.0% |
| PFG Investments, LLC | 15,500 | -50,500 | $80.3K | -$264.2K | -76.5% |
| Knoll Capital Management, LLC | 5,475,516 | 0 | $28.4M | -$219.0K | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 612,258 | -36,113 | $3.2M | -$213.1K | -5.6% |
| Nuveen, LLC | 108,220 | -36,465 | $560.6K | -$194.7K | -25.2% |
| NORTHERN TRUST CORP | 379,405 | -28,555 | $2.0M | -$164.2K | -7.0% |
| GROUP ONE TRADING, L.P. | 83,449 | -30,135 | $432.3K | -$160.6K | -26.5% |
| STRS OHIO | 68,200 | -17,500 | $353.3K | -$94.1K | -20.4% |
| IEQ CAPITAL, LLC | 144,199 | -14,954 | $747.0K | -$83.8K | -9.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,170,537 | -5,883 | $6.1M | -$77.6K | -0.5% |
| STATE STREET CORP | 1,098,600 | -4,074 | $5.7M | -$65.2K | -0.4% |
| WELLINGTON MANAGEMENT GROUP LLP | 178,851 | -10,970 | $926.4K | -$64.4K | -5.8% |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 47,475 | -1,165 | $245.9K | +$54.8K | -2.4% |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 32,683 | -159 | $132.7K | -$51.6K | -0.5% |
| Cerity Partners LLC | 51,049 | -9,307 | $264.4K | -$50.6K | -15.4% |
| RHUMBLINE ADVISERS | 70,413 | -8,233 | $364.7K | -$45.8K | -10.5% |
| Mariner, LLC | 22,876 | -6,970 | $118.4K | -$37.4K | -23.4% |
| Police & Firemen's Retirement System of New Jersey | 10,721 | -6,911 | $55.5K | -$36.5K | -39.2% |
| Bank of New York Mellon Corp | 115,766 | -6,086 | $599.7K | -$36.4K | -5.0% |
| SEI INVESTMENTS CO | 33,287 | -6,072 | $172.4K | -$33.0K | -15.4% |
| Quantinno Capital Management LP | 45,988 | -5,336 | $238.2K | -$29.7K | -10.4% |
| JPMORGAN CHASE & CO | 21,989 | -5,133 | $113.9K | -$27.7K | -18.9% |
| Joseph P. Lucia & Associates, LLC | 26,732 | -4,859 | $138.5K | -$26.4K | -15.4% |
| Providence Wealth Advisors, LLC | 25,000 | 0 | $104.1K | -$24.4K | 0.0% |
| Buckingham Strategic Partners | 10,535 | -4,074 | $54.6K | -$20.6K | -27.9% |
| MERCER GLOBAL ADVISORS INC /ADV | 10,571 | -3,814 | $54.8K | -$20.3K | -26.5% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,021 | -2,138 | $88.2K | -$11.8K | -11.2% |
| WOODSTOCK CORP | 266,756 | 0 | $1.4M | -$10.7K | 0.0% |
| Palo Alto Investors LP | 225,465 | 0 | $1.2M | -$9.0K | 0.0% |
| CITIGROUP INC | 1,555 | -1,453 | $8.1K | -$7.6K | -48.3% |
| CAPTRUST FINANCIAL ADVISORS | 51,995 | -999 | $269.3K | -$7.3K | -1.9% |
| GAMMA Investing LLC | 297 | -757 | $1.5K | -$4.0K | -71.8% |
| Creative Planning | 34,521 | -327 | $178.8K | -$3.1K | -0.9% |
| ALLIANCEBERNSTEIN L.P. | 75,550 | 0 | $391.3K | -$3.0K | 0.0% |
| Clearstead Advisors, LLC | 10,007 | -501 | $51.8K | -$3.0K | -4.8% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 25,203 | -295 | $130.6K | -$2.5K | -1.1% |
| PNC Financial Services Group, Inc. | 546 | -467 | $2.8K | -$2.5K | -46.1% |
| ADVISOR GROUP HOLDINGS, INC. | 40 | -440 | $207 | -$2.3K | -91.7% |
| AMERIPRISE FINANCIAL INC | 35,304 | -105 | $182.9K | -$2.0K | -0.3% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,341 | -272 | $17.3K | -$1.6K | -7.5% |
| LPL Financial LLC | 34,916 | 0 | $180.9K | -$1.4K | 0.0% |
| FIRST MANHATTAN CO | 34,745 | 0 | $180.0K | -$1.4K | 0.0% |
| EverSource Wealth Advisors, LLC | 4,629 | -211 | $24.0K | -$1.3K | -4.3% |
| Legal & General Group Plc | 5,645 | -191 | $29.2K | -$1.2K | -3.3% |
| Pallas Capital Advisors LLC | 17,338 | -7 | $89.8K | -$730 | -0.0% |
| LETKO, BROSSEAU & ASSOCIATES INC | 17,300 | 0 | $89.6K | -$692 | 0.0% |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 13,388 | 0 | $69.3K | -$535 | 0.0% |
| CIBC Private Wealth Group, LLC | 10,505 | 0 | $54.4K | -$420 | 0.0% |
| Voya Investment Management LLC | 10,066 | 0 | $52.1K | -$403 | 0.0% |
| NEW YORK STATE COMMON RETIREMENT FUND | 9,598 | 0 | $49.7K | -$384 | 0.0% |
| True Wealth Design, LLC | 174 | -56 | $902 | -$299 | -24.3% |
| Ameritas Investment Partners, Inc. | 3,846 | 0 | $19.9K | -$154 | 0.0% |
| GSA CAPITAL PARTNERS LLP | 96,917 | -25,747 | $502 | -$138 | -21.0% |
| Washington Trust Advisors, Inc. | 2,800 | 0 | $14.5K | -$112 | 0.0% |
| CWM, LLC | 43,305 | -15,074 | $224 | -$81 | -25.8% |
| ROTHSCHILD INVESTMENT LLC | 125 | -10 | $648 | -$57 | -7.4% |
| Optiver Holding B.V. | 980 | 0 | $5.1K | -$40 | 0.0% |
| SBI Securities Co., Ltd. | 263 | 0 | $1.4K | -$11 | 0.0% |
| Truvestments Capital LLC | 265 | 0 | $1.4K | -$10 | 0.0% |
| QUADRANT CAPITAL GROUP LLC | 185 | 0 | $959 | -$7 | 0.0% |
| HighMark Wealth Management LLC | 155 | 0 | $802 | -$7 | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 97 | 0 | $502 | -$4 | 0.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 64,262 | 0 | $333 | -$3 | 0.0% |
| King Wealth | 10,800 | -300 | $56 | -$2 | -2.7% |
| Hikari Power Ltd | 20,020 | 0 | $104 | -$1 | 0.0% |
| TD Waterhouse Canada Inc. | 15 | 0 | $78 | -$1 | 0.0% |
Sold Out(17)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MARSHALL WACE, LLP | 0 | -160,213 | $0 | -$836.3K | — |
| Savant Capital, LLC | 0 | -144,061 | $0 | -$752.0K | — |
| Y-Intercept (Hong Kong) Ltd | 0 | -138,091 | $0 | -$720.8K | — |
| Cubist Systematic Strategies, LLC | 0 | -101,375 | $0 | -$529.2K | — |
| CIBC Bancorp USA Inc. | 0 | -57,242 | $0 | -$298.8K | — |
| BRIGHTON JONES LLC | 0 | -19,945 | $0 | -$104.1K | — |
| Quadrature Capital Ltd | 0 | -19,275 | $0 | -$100.5K | — |
| Brooklyn Investment Group | 0 | -12,691 | $0 | -$66.2K | — |
| Inscription Capital, LLC | 0 | -12,633 | $0 | -$65.9K | — |
| Krilogy Financial LLC | 0 | -10,407 | $0 | -$51.3K | — |
| New Millennium Group LLC | 0 | -2,460 | $0 | -$12.8K | — |
| Point72 Europe (London) LLP | 0 | -915 | $0 | -$4.8K | — |
| Pineridge Advisors LLC | 0 | -600 | $0 | -$3.1K | — |
| US BANCORP \DE\ | 0 | -554 | $0 | -$2.9K | — |
| Point72 (DIFC) Ltd | 0 | -213 | $0 | -$1.1K | — |
| COMMONWEALTH EQUITY SERVICES, LLC | 0 | -10,904 | $0 | -$57 | — |
| Sunbelt Securities, Inc. | 0 | -2 | $0 | -$10 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Knoll Capital Management, LLC | 5,475,516 | $28.4M | 0 | 0.0% |
| PERCEPTIVE ADVISORS LLC | 4,185,632 | $21.7M | -1,036,679 | -19.9% |
| BlackRock, Inc. | 3,850,103 | $19.9M | +45,183 | 1.2% |
| VANGUARD GROUP INC | 3,698,682 | $19.2M | +106,813 | 3.0% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,850,000 | $9.6M | +518,209 | 38.9% |
| D. E. Shaw & Co., Inc. | 1,601,324 | $8.3M | +221,481 | 16.1% |
| 683 Capital Management, LLC | 1,530,000 | $7.9M | +710,000 | 86.6% |
| ARDSLEY ADVISORY PARTNERS LP | 1,500,000 | $7.8M | -400,000 | -21.1% |
| KENNEDY CAPITAL MANAGEMENT LLC | 1,255,838 | $6.5M | +143,625 | 12.9% |
| AQR CAPITAL MANAGEMENT LLC | 1,226,922 | $6.4M | -278,438 | -18.5% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,170,537 | $6.1M | -5,883 | -0.5% |
| STATE STREET CORP | 1,098,600 | $5.7M | -4,074 | -0.4% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 968,751 | $5.0M | +21,200 | 2.2% |
| MORGAN STANLEY | 657,032 | $3.4M | -426,287 | -39.4% |
| DIMENSIONAL FUND ADVISORS LP | 612,258 | $3.2M | -36,113 | -5.6% |
| BANK OF AMERICA CORP /DE/ | 410,028 | $2.1M | +19,950 | 5.1% |
| JANE STREET GROUP, LLC | 383,352 | $2.0M | +97,634 | 34.2% |
| NORTHERN TRUST CORP | 379,405 | $2.0M | -28,555 | -7.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 373,707 | $1.9M | +134,324 | 56.1% |
| WELLS FARGO & COMPANY/MN | 369,169 | $1.9M | +7,700 | 2.1% |
New & Closed Positions this quarter
Closed Positions
17 managers exited
Top five by prior-quarter value
- MARSHALL WACE, LLP$836.3K
- Savant Capital, LLC$752.0K
- Y-Intercept (Hong Kong) Ltd$720.8K
- Cubist Systematic Strategies, LLC$529.2K
- CIBC Bancorp USA Inc.$298.8K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ALDX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.