New Positions
16 managers initiated
Top five by reported value
Vistagen Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:VTGN
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
16 new19 added24 reduced16 exited
Total Institutional Holders
59
as of 2025-12-31
Top Holder
ORBIMED ADVISORS LLC
$2.1M
Largest QoQ Increase
ADAR1 Capital Management, LLC
+630,513 sh
Largest QoQ Decrease
JANUS HENDERSON GROUP PLC
-4,165,767 sh
New Positions(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| LUMINUS MANAGEMENT LLC | 350,000 | +350,000 | $231.7K | +$231.7K | — |
| OMERS ADMINISTRATION Corp | 103,400 | +103,400 | $68.4K | +$68.4K | — |
| Caption Management, LLC | 78,170 | +78,170 | $51.7K | +$51.7K | — |
| TUDOR INVESTMENT CORP ET AL | 76,172 | +76,172 | $50.4K | +$50.4K | — |
| Seven Fleet Capital Management LP | 62,701 | +62,701 | $41.5K | +$41.5K | — |
| Qube Research & Technologies Ltd | 60,139 | +60,139 | $39.8K | +$39.8K | — |
| Engineers Gate Manager LP | 30,490 | +30,490 | $20.2K | +$20.2K | — |
| Lighthouse Investment Partners, LLC | 20,580 | +20,580 | $13.6K | +$13.6K | — |
| Shay Capital LLC | 20,200 | +20,200 | $13.4K | +$13.4K | — |
| MARSHALL WACE, LLP | 19,973 | +19,973 | $13.2K | +$13.2K | — |
| StoneX Group Inc. | 13,349 | +13,349 | $8.8K | +$8.8K | — |
| DRW Securities, LLC | 10,000 | +10,000 | $6.6K | +$6.6K | — |
| Tower Research Capital LLC (TRC) | 8,564 | +8,564 | $5.7K | +$5.7K | — |
| Virtu Financial LLC | 37,739 | +37,739 | $25 | +$25 | — |
| HRT FINANCIAL LP | 37,585 | +37,585 | $24 | +$24 | — |
| FNY Investment Advisers, LLC | 6,000 | +6,000 | $21 | +$21 | — |
Added To(19)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 1,824,738 | +137,003 | $1.2M | -$4.8M | 8.1% |
| CITADEL ADVISORS LLC | 851,700 | +387,538 | $563.7K | -$1.1M | 83.5% |
| GEODE CAPITAL MANAGEMENT, LLC | 352,836 | +54,556 | $233.6K | -$825.7K | 18.3% |
| JANE STREET GROUP, LLC | 606,827 | +289,644 | $401.7K | -$724.3K | 91.3% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 825,186 | +493,792 | $545.3K | -$631.2K | 149.0% |
| AdvisorShares Investments LLC | 250,188 | +43,190 | $165.6K | -$569.2K | 20.9% |
| STATE STREET CORP | 121,114 | +24,256 | $80.2K | -$263.7K | 25.0% |
| DIMENSIONAL FUND ADVISORS LP | 151,874 | +83,857 | $100.6K | -$140.8K | 123.3% |
| NORTHERN TRUST CORP | 72,655 | +24,562 | $48.1K | -$122.6K | 51.1% |
| AMERICAN CENTURY COMPANIES INC | 48,770 | +7,698 | $32.3K | -$113.5K | 18.7% |
| OCCUDO QUANTITATIVE STRATEGIES LP | 59,038 | +16,334 | $39.1K | -$112.5K | 38.2% |
| ADAR1 Capital Management, LLC | 743,575 | +630,513 | $492.2K | +$90.8K | 557.7% |
| MILLENNIUM MANAGEMENT LLC | 197,045 | +176,369 | $130.4K | +$57.0K | 853.0% |
| UBS Group AG | 51,993 | +26,326 | $34.4K | -$56.7K | 102.6% |
| Kestra Advisory Services, LLC | 26,033 | +6,000 | $17.2K | -$53.9K | 29.9% |
| GROUP ONE TRADING, L.P. | 106,137 | +77,209 | $70.3K | -$32.4K | 266.9% |
| Schonfeld Strategic Advisors LLC | 21,736 | +10,853 | $14.4K | -$24.2K | 99.7% |
| Truvestments Capital LLC | 16,992 | +8,337 | $11.2K | -$19.5K | 96.3% |
| ADVISOR GROUP HOLDINGS, INC. | 5,269 | +1,176 | $3.5K | -$11.0K | 28.7% |
Reduced(24)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 3,105,200 | 0 | $2.1M | -$9.0M | 0.0% |
| TCG Crossover Management, LLC | 2,676,580 | 0 | $1.8M | -$7.7M | 0.0% |
| STEMPOINT CAPITAL LP | 616,749 | -1,871,936 | $142.1K | -$7.6M | -75.2% |
| Ikarian Capital, LLC | 519,077 | -101,792 | $343.6K | -$1.9M | -16.4% |
| DIADEMA PARTNERS LP | 206,500 | -243,489 | $136.7K | -$1.5M | -54.1% |
| RENAISSANCE TECHNOLOGIES LLC | 160,791 | -261,221 | $106.4K | -$1.4M | -61.9% |
| BlackRock, Inc. | 422,759 | -369 | $279.8K | -$1.2M | -0.1% |
| JPMORGAN CHASE & CO | 16 | -271,809 | $11 | -$965.0K | -100.0% |
| TWO SIGMA INVESTMENTS, LP | 195,570 | -93,839 | $129.4K | -$898.0K | -32.4% |
| BOOTHBAY FUND MANAGEMENT, LLC | 134,571 | -62,453 | $89.1K | -$610.4K | -31.7% |
| TWO SIGMA ADVISERS, LP | 137,732 | -19,300 | $91.2K | -$466.3K | -12.3% |
| Persistent Asset Partners Ltd | 26,612 | -48,707 | $17.6K | -$249.8K | -64.7% |
| BANK OF AMERICA CORP /DE/ | 3,145 | -31,512 | $2.1K | -$121.0K | -90.9% |
| MORGAN STANLEY | 12,658 | -14,876 | $8.4K | -$89.4K | -54.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,302 | 0 | $15.4K | -$67.3K | 0.0% |
| HighTower Advisors, LLC | 20,628 | -200 | $13.7K | -$60.3K | -1.0% |
| Performa Ltd (US), LLC | 1,000 | 0 | $662 | -$2.9K | 0.0% |
| MAI Capital Management | 526 | 0 | $349 | -$1.5K | 0.0% |
| SBI Securities Co., Ltd. | 288 | -2 | $191 | -$839 | -0.7% |
| JONES FINANCIAL COMPANIES LLLP | 114 | 0 | $75 | -$327 | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 13 | -43 | $9 | -$190 | -76.8% |
| Fairman Group, LLC | 29 | 0 | $19 | -$84 | 0.0% |
| BARCLAYS PLC | 1 | 0 | $2 | -$2 | 0.0% |
| CWM, LLC | 582 | 0 | $0 | -$2 | 0.0% |
Sold Out(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 0 | -4,165,767 | $0 | -$14.7M | — |
| Nantahala Capital Management, LLC | 0 | -1,978,492 | $0 | -$7.0M | — |
| COMMODORE CAPITAL LP | 0 | -1,575,000 | $0 | -$5.6M | — |
| Soleus Capital Management, L.P. | 0 | -550,000 | $0 | -$2.0M | — |
| Almitas Capital LLC | 0 | -261,399 | $0 | -$928.0K | — |
| BML Capital Management, LLC | 0 | -150,000 | $0 | -$532.5K | — |
| XTX Topco Ltd | 0 | -69,712 | $0 | -$247.5K | — |
| Walleye Capital LLC | 0 | -67,770 | $0 | -$240.6K | — |
| GOLDMAN SACHS GROUP INC | 0 | -60,152 | $0 | -$213.5K | — |
| Cubist Systematic Strategies, LLC | 0 | -43,953 | $0 | -$156.0K | — |
| Quadrature Capital Ltd | 0 | -15,752 | $0 | -$55.8K | — |
| BLAIR WILLIAM & CO/IL | 0 | -12,573 | $0 | -$44.6K | — |
| CITIGROUP INC | 0 | -3,453 | $0 | -$12.3K | — |
| Royal Bank of Canada | 0 | -4,208 | $0 | -$9.0K | — |
| GSA CAPITAL PARTNERS LLP | 0 | -31,486 | $0 | -$112 | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -59 | $0 | -$110 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 3,105,200 | $2.1M | 0 | 0.0% |
| TCG Crossover Management, LLC | 2,676,580 | $1.8M | 0 | 0.0% |
| VANGUARD GROUP INC | 1,824,738 | $1.2M | +137,003 | 8.1% |
| CITADEL ADVISORS LLC | 851,700 | $563.7K | +387,538 | 83.5% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 825,186 | $545.3K | +493,792 | 149.0% |
| ADAR1 Capital Management, LLC | 743,575 | $492.2K | +630,513 | 557.7% |
| JANE STREET GROUP, LLC | 606,827 | $401.7K | +289,644 | 91.3% |
| Ikarian Capital, LLC | 519,077 | $343.6K | -101,792 | -16.4% |
| BlackRock, Inc. | 422,759 | $279.8K | -369 | -0.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 352,836 | $233.6K | +54,556 | 18.3% |
| LUMINUS MANAGEMENT LLC | 350,000 | $231.7K | +350,000 | — |
| AdvisorShares Investments LLC | 250,188 | $165.6K | +43,190 | 20.9% |
| STEMPOINT CAPITAL LP | 616,749 | $142.1K | -1,871,936 | -75.2% |
| DIADEMA PARTNERS LP | 206,500 | $136.7K | -243,489 | -54.1% |
| MILLENNIUM MANAGEMENT LLC | 197,045 | $130.4K | +176,369 | 853.0% |
| TWO SIGMA INVESTMENTS, LP | 195,570 | $129.4K | -93,839 | -32.4% |
| RENAISSANCE TECHNOLOGIES LLC | 160,791 | $106.4K | -261,221 | -61.9% |
| DIMENSIONAL FUND ADVISORS LP | 151,874 | $100.6K | +83,857 | 123.3% |
| TWO SIGMA ADVISERS, LP | 137,732 | $91.2K | -19,300 | -12.3% |
| BOOTHBAY FUND MANAGEMENT, LLC | 134,571 | $89.1K | -62,453 | -31.7% |
New & Closed Positions this quarter
Closed Positions
16 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for VTGN against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.