New Positions
33 managers initiated
Top five by reported value
Schrodinger Inc NASDAQ NMS - GLOBAL MARKET:SDGR
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
33 new77 added115 reduced30 exited
Total Institutional Holders
225
as of 2025-12-31
Top Holder
BlackRock, Inc.
$170.2M
Largest QoQ Increase
UBS Group AG
+489,059 sh
Largest QoQ Decrease
Rubric Capital Management LP
-1,097,319 sh
New Positions(33)
Added To(77)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 6,464,426 | +125,349 | $115.6M | -$11.6M | 2.0% |
| Sumitomo Mitsui Trust Holdings, Inc. | 4,714,767 | +160,198 | $84.3M | -$7.1M | 3.5% |
| UBS Group AG | 1,442,799 | +489,059 | $25.8M | +$6.7M | 51.3% |
| Man Group plc | 441,363 | +278,189 | $7.9M | +$4.6M | 170.5% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 864,270 | +313,571 | $15.5M | +$4.4M | 56.9% |
| Stephens Investment Management Group LLC | 2,250,098 | +57,064 | $40.2M | -$3.8M | 2.6% |
| Connor, Clark & Lunn Investment Management Ltd. | 273,254 | +185,632 | $4.9M | +$3.1M | 211.8% |
| FRED ALGER MANAGEMENT, LLC | 269,825 | +166,706 | $4.8M | +$2.8M | 161.7% |
| Nikko Asset Management Americas, Inc. | 2,819,670 | +180,735 | $50.4M | -$2.6M | 6.8% |
| PEAK6 LLC | 1,361,900 | +269,200 | $24.4M | +$2.4M | 24.6% |
| Susquehanna Portfolio Strategies, LLC | 158,162 | +129,877 | $2.8M | +$2.3M | 459.2% |
| AQR CAPITAL MANAGEMENT LLC | 161,721 | +126,303 | $2.9M | +$2.2M | 356.6% |
| AMERICAN CENTURY COMPANIES INC | 1,107,677 | +22,249 | $19.8M | -$2.0M | 2.0% |
| FARALLON CAPITAL MANAGEMENT LLC | 355,000 | +71,000 | $7.0M | +$1.3M | 25.0% |
| BNP PARIBAS ARBITRAGE, SNC | 118,692 | +68,364 | $2.1M | +$1.1M | 135.8% |
| TUDOR INVESTMENT CORP ET AL | 438,925 | +102,546 | $7.8M | +$1.1M | 30.5% |
| DIMENSIONAL FUND ADVISORS LP | 1,012,631 | +161,242 | $18.1M | +$1.0M | 18.9% |
| Engineers Gate Manager LP | 65,399 | +52,035 | $1.2M | +$901.3K | 389.4% |
| BARCLAYS PLC | 147,974 | +42,767 | $3.0M | +$866.8K | 40.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,384,788 | +108,005 | $24.8M | -$851.4K | 8.4% |
| GOLDMAN SACHS GROUP INC | 669,468 | +107,346 | $12.0M | +$693.9K | 19.1% |
| MARSHALL WACE, LLP | 80,774 | +42,288 | $1.4M | +$672.2K | 109.9% |
| CAPITAL FUND MANAGEMENT S.A. | 72,968 | +40,785 | $1.3M | +$659.1K | 126.7% |
| Schonfeld Strategic Advisors LLC | 65,640 | +39,232 | $1.2M | +$643.9K | 148.6% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 2,291,349 | +218,916 | $41.0M | -$603.7K | 10.6% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 515,903 | +30,447 | $9.2M | -$513.9K | 6.3% |
| FOX RUN MANAGEMENT, L.L.C. | 47,831 | +30,042 | $855.2K | +$498.4K | 168.9% |
| EntryPoint Capital, LLC | 44,319 | +28,924 | $792.4K | +$483.6K | 187.9% |
| Slow Capital, Inc. | 131,263 | +37,374 | $2.3M | +$463.6K | 39.8% |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 68,759 | +27,385 | $1.2M | +$399.4K | 66.2% |
| Swiss National Bank | 127,200 | +2,800 | $2.3M | -$221.1K | 2.3% |
| Invesco Ltd. | 190,763 | +10,307 | $3.4M | -$209.1K | 5.7% |
| Brevan Howard Capital Management LP | 44,592 | +15,182 | $797.3K | +$207.3K | 51.6% |
| UBS ASSET MANAGEMENT AMERICAS INC | 3,717,890 | +414,231 | $66.5M | +$204.5K | 12.5% |
| ARK Investment Management LLC | 2,111,829 | +239,152 | $37.8M | +$193.6K | 12.8% |
| Russell Investments Group, Ltd. | 15,637 | +10,689 | $279.6K | +$180.3K | 216.0% |
| Verity Asset Management, Inc. | 65,722 | +798 | $1.2M | -$127.3K | 1.2% |
| ANTIPODES PARTNERS Ltd | 11,464 | +6,552 | $205.0K | +$106.5K | 133.4% |
| Walleye Trading LLC | 25,500 | +7,200 | $455.9K | +$88.8K | 39.3% |
| SEI INVESTMENTS CO | 39,139 | +8,240 | $699.8K | +$80.0K | 26.7% |
| Perigon Wealth Management, LLC | 20,705 | +5,803 | $370.2K | +$71.3K | 38.9% |
| Kestra Advisory Services, LLC | 50,427 | +8,966 | $901.6K | +$69.9K | 21.6% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 61,601 | +3,215 | $1.1M | -$69.8K | 5.5% |
| WELLS FARGO & COMPANY/MN | 112,525 | +15,317 | $2.0M | +$62.0K | 15.8% |
| Hennion & Walsh Asset Management, Inc. | 15,466 | +4,350 | $276.5K | +$53.5K | 39.1% |
| GROUP ONE TRADING, L.P. | 19,235 | +3,985 | $343.9K | +$38.0K | 26.1% |
| IMC-Chicago, LLC | 32,708 | +1,661 | $584.8K | -$38.0K | 5.3% |
| NEOS Investment Management LLC | 20,373 | +3,540 | $364.3K | +$26.6K | 21.0% |
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND | 12,800 | +200 | $228.9K | -$23.9K | 1.6% |
| Redwood Wealth Management Group, LLC | 13,428 | +361 | $240.1K | -$22.0K | 2.8% |
| TEMA ETFS LLC | 20,073 | +3,240 | $358.9K | +$21.2K | 19.2% |
| EverSource Wealth Advisors, LLC | 1,374 | +1,207 | $24.6K | +$21.2K | 722.8% |
| ProShare Advisors LLC | 10,946 | +343 | $195.7K | -$17.0K | 3.2% |
| DEUTSCHE BANK AG\ | 46,332 | +4,271 | $828.4K | -$15.3K | 10.2% |
| CAPTRUST FINANCIAL ADVISORS | 21,699 | +1,655 | $388.0K | -$14.1K | 8.3% |
| Clearstead Trust, LLC | 565 | +545 | $10.1K | +$9.7K | 2725.0% |
| SIGNATUREFD, LLC | 515 | +503 | $9.2K | +$9.0K | 4191.7% |
| STEPHENS INC /AR/ | 12,618 | +1,724 | $225.6K | +$7.1K | 15.8% |
| JONES FINANCIAL COMPANIES LLLP | 1,486 | +438 | $26.6K | +$6.3K | 41.8% |
| Sterling Capital Management LLC | 374 | +238 | $6.7K | +$4.0K | 175.0% |
| ALGERT GLOBAL LLC | 211,427 | +177,537 | $3.8K | +$3.1K | 523.9% |
| Prestige Wealth Management Group LLC | 225 | +120 | $4.5K | +$2.4K | 114.3% |
| Farther Finance Advisors, LLC | 452 | +159 | $8.1K | +$2.2K | 54.3% |
| HRT FINANCIAL LP | 164,576 | +118,157 | $2.9K | +$2.0K | 254.5% |
| Gen-Wealth Partners Inc | 135 | +112 | $2.4K | +$2.0K | 486.9% |
| Entropy Technologies, LP | 12,946 | +1,336 | $231.5K | -$1.4K | 11.5% |
| Parallel Advisors, LLC | 106 | +45 | $1.9K | +$671 | 73.8% |
| SG Americas Securities, LLC | 65,151 | +27,023 | $1.2K | +$400 | 70.9% |
| KLP KAPITALFORVALTNING AS | 13,700 | +1,500 | $245.0K | +$224 | 12.3% |
| CWM, LLC | 5,951 | +5,531 | $106 | +$98 | 1316.9% |
| HARBOR CAPITAL ADVISORS, INC. | 25,875 | +6,601 | $463 | +$76 | 34.2% |
| State of Alaska, Department of Revenue | 28,573 | +362 | $510 | -$55 | 1.3% |
| HANTZ FINANCIAL SERVICES, INC. | 1,589 | +1,558 | $28 | +$27 | 5025.8% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 60,897 | +7,919 | $1.1K | +$26 | 14.9% |
| Handelsbanken Fonder AB | 15,200 | +900 | $272 | -$15 | 6.3% |
| T. Rowe Price Investment Management, Inc. | 1,033 | +445 | $19 | +$7 | 75.7% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 754 | +215 | $13 | +$2 | 39.9% |
Reduced(115)
Sold Out(30)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| BlackRock, Inc. | 9,517,096 | $170.2M | -44,043 | -0.5% |
| BILL & MELINDA GATES FOUNDATION TRUST | 6,981,664 | $124.8M | 0 | 0.0% |
| VANGUARD GROUP INC | 6,464,426 | $115.6M | +125,349 | 2.0% |
| Sumitomo Mitsui Trust Holdings, Inc. | 4,714,767 | $84.3M | +160,198 | 3.5% |
| Rubric Capital Management LP | 4,171,498 | $74.6M | -1,097,319 | -20.8% |
| UBS ASSET MANAGEMENT AMERICAS INC | 3,717,890 | $66.5M | +414,231 | 12.5% |
| Nikko Asset Management Americas, Inc. | 2,819,670 | $50.4M | +180,735 | 6.8% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 2,291,349 | $41.0M | +218,916 | 10.6% |
| Stephens Investment Management Group LLC | 2,250,098 | $40.2M | +57,064 | 2.6% |
| LAZARD ASSET MANAGEMENT LLC | 2,134,968 | $38.2M | -211,473 | -9.0% |
| STATE STREET CORP | 2,131,906 | $38.1M | -73,128 | -3.3% |
| ARK Investment Management LLC | 2,111,829 | $37.8M | +239,152 | 12.8% |
| UBS Group AG | 1,442,799 | $25.8M | +489,059 | 51.3% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,384,788 | $24.8M | +108,005 | 8.4% |
| PEAK6 LLC | 1,361,900 | $24.4M | +269,200 | 24.6% |
| MORGAN STANLEY | 1,186,698 | $21.2M | -550,732 | -31.7% |
| AMERICAN CENTURY COMPANIES INC | 1,107,677 | $19.8M | +22,249 | 2.0% |
| DIMENSIONAL FUND ADVISORS LP | 1,012,631 | $18.1M | +161,242 | 18.9% |
| MILLENNIUM MANAGEMENT LLC | 978,172 | $17.5M | -573,549 | -37.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 864,270 | $15.5M | +313,571 | 56.9% |
New & Closed Positions this quarter
Closed Positions
30 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for SDGR against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.