New Positions
39 managers initiated
Top five by reported value
Rani Therapeutics Holdings Inc NASDAQ NMS - GLOBAL MARKET:RANI
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
39 new15 added12 reduced10 exited
Total Institutional Holders
66
as of 2025-12-31
Top Holder
Samsara BioCapital, LLC
$11.5M
Largest QoQ Increase
RA CAPITAL MANAGEMENT, L.P.
+8,500,000 sh
Largest QoQ Decrease
CITADEL ADVISORS LLC
-224,342 sh
New Positions(39)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Samsara BioCapital, LLC | 8,500,000 | +8,500,000 | $11.5M | +$11.5M | — |
| RA CAPITAL MANAGEMENT, L.P. | 8,500,000 | +8,500,000 | $11.5M | +$11.5M | — |
| AWM Investment Company, Inc. | 6,500,000 | +6,500,000 | $8.8M | +$8.8M | — |
| SymBiosis Capital Partners, LLC | 6,300,000 | +6,300,000 | $8.5M | +$8.5M | — |
| Longaeva Partners L.P. | 2,113,435 | +2,113,435 | $2.9M | +$2.9M | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,033,622 | +2,033,622 | $2.7M | +$2.7M | — |
| Siren, L.L.C. | 2,000,000 | +2,000,000 | $2.7M | +$2.7M | — |
| JANE STREET GROUP, LLC | 1,344,800 | +1,344,800 | $1.8M | +$1.8M | — |
| 683 Capital Management, LLC | 487,168 | +487,168 | $657.7K | +$657.7K | — |
| Squarepoint Ops LLC | 344,378 | +344,378 | $464.9K | +$464.9K | — |
| GOLDMAN SACHS GROUP INC | 285,832 | +285,832 | $385.9K | +$385.9K | — |
| MILLENNIUM MANAGEMENT LLC | 163,300 | +163,300 | $220.5K | +$220.5K | — |
| Qube Research & Technologies Ltd | 148,226 | +148,226 | $200.1K | +$200.1K | — |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114,500 | +114,500 | $154.6K | +$154.6K | — |
| FARALLON CAPITAL MANAGEMENT LLC | 78,000 | +78,000 | $105.3K | +$105.3K | — |
| OMERS ADMINISTRATION Corp | 69,200 | +69,200 | $93.4K | +$93.4K | — |
| CITIGROUP INC | 53,095 | +53,095 | $71.7K | +$71.7K | — |
| Lighthouse Investment Partners, LLC | 42,840 | +42,840 | $57.8K | +$57.8K | — |
| TWO SIGMA SECURITIES, LLC | 35,874 | +35,874 | $48.4K | +$48.4K | — |
| Jefferies Financial Group Inc. | 29,870 | +29,870 | $40.3K | +$40.3K | — |
| China Universal Asset Management Co., Ltd. | 15,894 | +15,894 | $21.5K | +$21.5K | — |
| Bronte Capital Management Pty Ltd. | 14,868 | +14,868 | $20.1K | +$20.1K | — |
| Balyasny Asset Management LLC | 14,655 | +14,655 | $19.8K | +$19.8K | — |
| Farther Finance Advisors, LLC | 13,800 | +13,800 | $18.6K | +$18.6K | — |
| Disciplined Investors, L.L.C. | 12,200 | +12,200 | $16.5K | +$16.5K | — |
| Sanctuary Advisors, LLC | 12,014 | +12,014 | $16.2K | +$16.2K | — |
| EWA, LLC | 11,081 | +11,081 | $15.0K | +$15.0K | — |
| CARY STREET PARTNERS FINANCIAL LLC | 10,550 | +10,550 | $14.2K | +$14.2K | — |
| BARCLAYS PLC | 8,096 | +8,096 | $10.9K | +$10.9K | — |
| Mirae Asset Global Investments Co., Ltd. | 4,740 | +4,740 | $6.4K | +$6.4K | — |
| Allworth Financial LP | 3,119 | +3,119 | $4.2K | +$4.2K | — |
| T3 Companies, LLC | 363,000 | +363,000 | $2.9K | +$2.9K | — |
| State of Wyoming | 2,076 | +2,076 | $2.8K | +$2.8K | — |
| GF FUND MANAGEMENT CO. LTD. | 1,857 | +1,857 | $2.5K | +$2.5K | — |
| BNP PARIBAS ARBITRAGE, SNC | 1,616 | +1,616 | $2.2K | +$2.2K | — |
| JONES FINANCIAL COMPANIES LLLP | 1,000 | +1,000 | $1.4K | +$1.4K | — |
| Elyxium Wealth, LLC | 760 | +760 | $1.0K | +$1.0K | — |
| Virtu Financial LLC | 51,178 | +51,178 | $69 | +$69 | — |
| CWM, LLC | 175 | +175 | $0 | $0 | — |
Added To(15)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 5,109,368 | +4,224,759 | $6.9M | +$6.5M | 477.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 860,941 | +564,031 | $1.2M | +$1.0M | 190.0% |
| BlackRock, Inc. | 527,712 | +407,480 | $712.4K | +$652.3K | 338.9% |
| STATE STREET CORP | 387,042 | +324,600 | $522.5K | +$491.3K | 519.8% |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 254,812 | +28,670 | $344.0K | +$231.0K | 12.7% |
| NORTHERN TRUST CORP | 170,471 | +73,466 | $230.1K | +$181.7K | 75.7% |
| UBS Group AG | 151,523 | +82,400 | $204.6K | +$170.0K | 119.2% |
| BANK OF AMERICA CORP /DE/ | 36,607 | +18,855 | $49.4K | +$40.6K | 106.2% |
| MORGAN STANLEY | 28,677 | +21,927 | $38.7K | +$35.3K | 324.8% |
| Lafayette Investments, Inc. | 22,979 | +3,086 | $31.0K | +$21.1K | 15.5% |
| ACT Advisors, LLC. | 16,062 | +1,256 | $21.7K | +$14.3K | 8.5% |
| SBI Securities Co., Ltd. | 13,788 | +1,156 | $18.6K | +$12.3K | 9.2% |
| JPMORGAN CHASE & CO | 7,819 | +7,748 | $10.6K | +$10.5K | 10912.7% |
| Tower Research Capital LLC (TRC) | 7,685 | +1,461 | $10.4K | +$7.3K | 23.5% |
| Royal Bank of Canada | 127 | +96 | $0 | $0 | 309.7% |
Reduced(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Nan Fung Group Holdings Ltd | 493,584 | 0 | $666.3K | +$419.6K | 0.0% |
| UNITED SERVICES AUTOMOBILE ASSOCIATION | 302,743 | 0 | $408.7K | +$257.4K | 0.0% |
| CWA Asset Management Group, LLC | 150,000 | 0 | $202.5K | +$127.5K | 0.0% |
| CITADEL ADVISORS LLC | 228,200 | -224,342 | $308.1K | +$81.9K | -49.6% |
| KING LUTHER CAPITAL MANAGEMENT CORP | 58,000 | 0 | $78.3K | +$49.3K | 0.0% |
| Well Done, LLC | 52,014 | 0 | $70.2K | +$44.2K | 0.0% |
| MOTCO | 48,129 | 0 | $65.0K | +$40.9K | 0.0% |
| Prime Capital Investment Advisors, LLC | 27,208 | 0 | $36.7K | +$23.1K | 0.0% |
| Cerity Partners LLC | 10,000 | 0 | $13.5K | +$8.5K | 0.0% |
| ISLAY CAPITAL MANAGEMENT, LLC | 9,611 | 0 | $13.0K | +$8.2K | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 1,000 | 0 | $1.4K | +$860 | 0.0% |
| Janney Montgomery Scott LLC | 49,200 | 0 | $66 | +$41 | 0.0% |
Sold Out(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| TAKEDA PHARMACEUTICAL CO LTD | 0 | -203,190 | $0 | -$101.6K | — |
| LASRY MARC | 0 | -62,887 | $0 | -$31.4K | — |
| INSIGNEO ADVISORY SERVICES, LLC | 0 | -47,500 | $0 | -$23.7K | — |
| XTX Topco Ltd | 0 | -44,077 | $0 | -$22.0K | — |
| BROWN ADVISORY INC | 0 | -32,911 | $0 | -$16.4K | — |
| RENAISSANCE TECHNOLOGIES LLC | 0 | -24,908 | $0 | -$12.4K | — |
| CHOREO, LLC | 0 | -11,813 | $0 | -$5.9K | — |
| EverSource Wealth Advisors, LLC | 0 | -980 | $0 | -$490 | — |
| HRT FINANCIAL LP | 0 | -113,206 | $0 | -$56 | — |
| SIMPLEX TRADING, LLC | 0 | -819 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 8,500,000 | $11.5M | +8,500,000 | — |
| Samsara BioCapital, LLC | 8,500,000 | $11.5M | +8,500,000 | — |
| AWM Investment Company, Inc. | 6,500,000 | $8.8M | +6,500,000 | — |
| SymBiosis Capital Partners, LLC | 6,300,000 | $8.5M | +6,300,000 | — |
| VANGUARD GROUP INC | 5,109,368 | $6.9M | +4,224,759 | 477.6% |
| Longaeva Partners L.P. | 2,113,435 | $2.9M | +2,113,435 | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,033,622 | $2.7M | +2,033,622 | — |
| Siren, L.L.C. | 2,000,000 | $2.7M | +2,000,000 | — |
| JANE STREET GROUP, LLC | 1,344,800 | $1.8M | +1,344,800 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 860,941 | $1.2M | +564,031 | 190.0% |
| BlackRock, Inc. | 527,712 | $712.4K | +407,480 | 338.9% |
| Nan Fung Group Holdings Ltd | 493,584 | $666.3K | 0 | 0.0% |
| 683 Capital Management, LLC | 487,168 | $657.7K | +487,168 | — |
| STATE STREET CORP | 387,042 | $522.5K | +324,600 | 519.8% |
| Squarepoint Ops LLC | 344,378 | $464.9K | +344,378 | — |
| UNITED SERVICES AUTOMOBILE ASSOCIATION | 302,743 | $408.7K | 0 | 0.0% |
| GOLDMAN SACHS GROUP INC | 285,832 | $385.9K | +285,832 | — |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 254,812 | $344.0K | +28,670 | 12.7% |
| CITADEL ADVISORS LLC | 228,200 | $308.1K | -224,342 | -49.6% |
| NORTHERN TRUST CORP | 170,471 | $230.1K | +73,466 | 75.7% |
New & Closed Positions this quarter
Closed Positions
10 managers exited
Top five by prior-quarter value
- TAKEDA PHARMACEUTICAL CO LTD$101.6K
- LASRY MARC$31.4K
- INSIGNEO ADVISORY SERVICES, LLC$23.7K
- XTX Topco Ltd$22.0K
- BROWN ADVISORY INC$16.4K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for RANI against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.