New Positions
74 managers initiated
Top five by reported value
- Novo Holdings A/S$64.8M
- FCPM III SERVICES B.V.$56.7M
- GOLDMAN SACHS GROUP INC$34.0M
- BlackRock, Inc.$19.2M
- Nan Fung Group Holdings Ltd$17.1M
MapLight Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:MPLT
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31.
74 new0 added0 reduced0 exited
Total Institutional Holders
74
as of 2025-12-31
Top Holder
Novo Holdings A/S
$64.8M
Largest QoQ Increase
Novo Holdings A/S
+3,686,622 sh
Largest QoQ Decrease
—
New Positions(74)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Novo Holdings A/S | 3,686,622 | +3,686,622 | $64.8M | +$64.8M | — |
| FCPM III SERVICES B.V. | 3,226,400 | +3,226,400 | $56.7M | +$56.7M | — |
| GOLDMAN SACHS GROUP INC | 1,937,168 | +1,937,168 | $34.0M | +$34.0M | — |
| BlackRock, Inc. | 1,095,514 | +1,095,514 | $19.2M | +$19.2M | — |
| Nan Fung Group Holdings Ltd | 971,253 | +971,253 | $17.1M | +$17.1M | — |
| 5AM Venture Management, LLC | 950,011 | +950,011 | $16.7M | +$16.7M | — |
| Sanofi | 912,041 | +912,041 | $16.0M | +$16.0M | — |
| VANGUARD GROUP INC | 869,668 | +869,668 | $15.3M | +$15.3M | — |
| Pivotal bioVenture Partners Investment Advisor LLC | 611,447 | +611,447 | $10.7M | +$10.7M | — |
| PERCEPTIVE ADVISORS LLC | 550,000 | +550,000 | $9.7M | +$9.7M | — |
| Velan Capital Investment Management LP | 522,305 | +522,305 | $9.2M | +$9.2M | — |
| Siren, L.L.C. | 450,000 | +450,000 | $7.9M | +$7.9M | — |
| GEODE CAPITAL MANAGEMENT, LLC | 389,026 | +389,026 | $6.8M | +$6.8M | — |
| Vestal Point Capital, LP | 385,000 | +385,000 | $6.8M | +$6.8M | — |
| BAKER BROS. ADVISORS LP | 364,705 | +364,705 | $6.4M | +$6.4M | — |
| Jain Global LLC | 327,693 | +327,693 | $5.8M | +$5.8M | — |
| Blue Owl Capital Holdings LP | 327,058 | +327,058 | $5.7M | +$5.7M | — |
| STATE STREET CORP | 229,484 | +229,484 | $4.0M | +$4.0M | — |
| LAZARD ASSET MANAGEMENT LLC | 207,494 | +207,494 | $3.6M | +$3.6M | — |
| Board of Trustees of The Leland Stanford Junior University | 199,233 | +199,233 | $3.5M | +$3.5M | — |
| CITADEL ADVISORS LLC | 190,139 | +190,139 | $3.3M | +$3.3M | — |
| Freestone Grove Partners LP | 183,771 | +183,771 | $3.2M | +$3.2M | — |
| TFG Asset Management GP Ltd | 164,525 | +164,525 | $2.9M | +$2.9M | — |
| DAFNA Capital Management LLC | 143,764 | +143,764 | $2.5M | +$2.5M | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 138,427 | +138,427 | $2.4M | +$2.4M | — |
| NORTHERN TRUST CORP | 119,557 | +119,557 | $2.1M | +$2.1M | — |
| STEMPOINT CAPITAL LP | 100,000 | +100,000 | $1.8M | +$1.8M | — |
| SEVEN GRAND MANAGERS, LLC | 100,000 | +100,000 | $1.8M | +$1.8M | — |
| Burkehill Global Management, LP | 75,000 | +75,000 | $1.3M | +$1.3M | — |
| AMERIPRISE FINANCIAL INC | 66,872 | +66,872 | $1.2M | +$1.2M | — |
| DIADEMA PARTNERS LP | 63,791 | +63,791 | $1.1M | +$1.1M | — |
| ORBIMED ADVISORS LLC | 56,000 | +56,000 | $952.0K | +$952.0K | — |
| TUDOR INVESTMENT CORP ET AL | 47,840 | +47,840 | $840.3K | +$840.3K | — |
| MARSHALL WACE, LLP | 39,659 | +39,659 | $696.8K | +$696.8K | — |
| BANK OF AMERICA CORP /DE/ | 37,820 | +37,820 | $664.3K | +$664.3K | — |
| TD Asset Management Inc | 36,960 | +36,960 | $649.2K | +$649.2K | — |
| Bank of New York Mellon Corp | 35,857 | +35,857 | $629.8K | +$629.8K | — |
| BARCLAYS PLC | 26,415 | +26,415 | $464.0K | +$464.0K | — |
| MORGAN STANLEY | 23,222 | +23,222 | $407.9K | +$407.9K | — |
| Persistent Asset Partners Ltd | 21,766 | +21,766 | $382.3K | +$382.3K | — |
| Nuveen, LLC | 20,197 | +20,197 | $354.8K | +$354.8K | — |
| Ghisallo Capital Management LLC | 20,000 | +20,000 | $351.3K | +$351.3K | — |
| WELLS FARGO & COMPANY/MN | 18,687 | +18,687 | $328.2K | +$328.2K | — |
| UBS Group AG | 18,290 | +18,290 | $321.3K | +$321.3K | — |
| OXFORD ASSET MANAGEMENT LLP | 17,763 | +17,763 | $312.0K | +$312.0K | — |
| MILLENNIUM MANAGEMENT LLC | 13,945 | +13,945 | $244.9K | +$244.9K | — |
| RHUMBLINE ADVISERS | 13,642 | +13,642 | $239.6K | +$239.6K | — |
| Lynx1 Capital Management LP | 13,477 | +13,477 | $236.7K | +$236.7K | — |
| Invesco Ltd. | 12,970 | +12,970 | $227.8K | +$227.8K | — |
| DEUTSCHE BANK AG\ | 11,928 | +11,928 | $209.6K | +$209.6K | — |
| Walleye Capital LLC | 11,686 | +11,686 | $205.3K | +$205.3K | — |
| LMR Partners LLP | 10,000 | +10,000 | $175.7K | +$175.7K | — |
| MetLife Investment Management, LLC | 9,798 | +9,798 | $172.1K | +$172.1K | — |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 7,815 | +7,815 | $137.3K | +$137.3K | — |
| JPMORGAN CHASE & CO | 6,743 | +6,743 | $118.4K | +$118.4K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 5,300 | +5,300 | $93.1K | +$93.1K | — |
| Police & Firemen's Retirement System of New Jersey | 3,986 | +3,986 | $70.0K | +$70.0K | — |
| BNP PARIBAS ARBITRAGE, SNC | 3,455 | +3,455 | $60.7K | +$60.7K | — |
| STRS OHIO | 3,000 | +3,000 | $52.7K | +$52.7K | — |
| Tower Research Capital LLC (TRC) | 2,870 | +2,870 | $50.4K | +$50.4K | — |
| T. Rowe Price Investment Management, Inc. | 2,799,180 | +2,799,180 | $49.2K | +$49.2K | — |
| Legal & General Group Plc | 1,649 | +1,649 | $29.0K | +$29.0K | — |
| Ameritas Investment Partners, Inc. | 1,371 | +1,371 | $24.1K | +$24.1K | — |
| Russell Investments Group, Ltd. | 1,337 | +1,337 | $23.5K | +$23.5K | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,040 | +1,040 | $18.3K | +$18.3K | — |
| FMR LLC | 904 | +904 | $15.9K | +$15.9K | — |
| SBI Securities Co., Ltd. | 607 | +607 | $10.7K | +$10.7K | — |
| Royal Bank of Canada | 582 | +582 | $10.0K | +$10.0K | — |
| Sterling Capital Management LLC | 519 | +519 | $9.1K | +$9.1K | — |
| Federation des caisses Desjardins du Quebec | 500 | +500 | $8.8K | +$8.8K | — |
| CITIGROUP INC | 383 | +383 | $6.7K | +$6.7K | — |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 147,930 | +147,930 | $2.6K | +$2.6K | — |
| Farther Finance Advisors, LLC | 120 | +120 | $2.1K | +$2.1K | — |
| AMALGAMATED BANK | 530 | +530 | $9 | +$9 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Novo Holdings A/S | 3,686,622 | $64.8M | +3,686,622 | — |
| FCPM III SERVICES B.V. | 3,226,400 | $56.7M | +3,226,400 | — |
| GOLDMAN SACHS GROUP INC | 1,937,168 | $34.0M | +1,937,168 | — |
| BlackRock, Inc. | 1,095,514 | $19.2M | +1,095,514 | — |
| Nan Fung Group Holdings Ltd | 971,253 | $17.1M | +971,253 | — |
| 5AM Venture Management, LLC | 950,011 | $16.7M | +950,011 | — |
| Sanofi | 912,041 | $16.0M | +912,041 | — |
| VANGUARD GROUP INC | 869,668 | $15.3M | +869,668 | — |
| Pivotal bioVenture Partners Investment Advisor LLC | 611,447 | $10.7M | +611,447 | — |
| PERCEPTIVE ADVISORS LLC | 550,000 | $9.7M | +550,000 | — |
| Velan Capital Investment Management LP | 522,305 | $9.2M | +522,305 | — |
| Siren, L.L.C. | 450,000 | $7.9M | +450,000 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 389,026 | $6.8M | +389,026 | — |
| Vestal Point Capital, LP | 385,000 | $6.8M | +385,000 | — |
| BAKER BROS. ADVISORS LP | 364,705 | $6.4M | +364,705 | — |
| Jain Global LLC | 327,693 | $5.8M | +327,693 | — |
| Blue Owl Capital Holdings LP | 327,058 | $5.7M | +327,058 | — |
| STATE STREET CORP | 229,484 | $4.0M | +229,484 | — |
| LAZARD ASSET MANAGEMENT LLC | 207,494 | $3.6M | +207,494 | — |
| Board of Trustees of The Leland Stanford Junior University | 199,233 | $3.5M | +199,233 | — |
New & Closed Positions this quarter
Closed Positions
0 managers exited
Top five by prior-quarter value
No managers exited their positions this quarter.
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for MPLT against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.