New Positions
24 managers initiated
Top five by reported value
MeiraGTx Holdings PLC NASDAQ NMS - GLOBAL MARKET:MGTX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
24 new42 added63 reduced14 exited
Total Institutional Holders
129
as of 2025-12-31
Top Holder
Sanofi
$97.0M
Largest QoQ Increase
Rubric Capital Management LP
+2,448,880 sh
Largest QoQ Decrease
PERCEPTIVE ADVISORS LLC
-2,300,000 sh
New Positions(24)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Opaleye Management Inc. | 390,844 | +390,844 | $3.1M | +$3.1M | — |
| Jefferies Financial Group Inc. | 298,242 | +298,242 | $2.4M | +$2.4M | — |
| ROYCE & ASSOCIATES LP | 176,057 | +176,057 | $1.4M | +$1.4M | — |
| Trexquant Investment LP | 67,537 | +67,537 | $536.9K | +$536.9K | — |
| Y-Intercept (Hong Kong) Ltd | 65,558 | +65,558 | $521.2K | +$521.2K | — |
| RAYMOND JAMES FINANCIAL INC | 57,232 | +57,232 | $455.0K | +$455.0K | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 56,235 | +56,235 | $447.1K | +$447.1K | — |
| VARCOV Co. | 32,945 | +32,945 | $261.9K | +$261.9K | — |
| Virtus Investment Advisers, Inc. | 29,824 | +29,824 | $237.1K | +$237.1K | — |
| AlphaCentric Advisors LLC | 28,496 | +28,496 | $226.5K | +$226.5K | — |
| Engineers Gate Manager LP | 26,839 | +26,839 | $213.4K | +$213.4K | — |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 22,578 | +22,578 | $176.3K | +$176.3K | — |
| Voleon Capital Management LP | 16,587 | +16,587 | $131.9K | +$131.9K | — |
| Perigon Wealth Management, LLC | 15,000 | +15,000 | $119.3K | +$119.3K | — |
| Abel Hall, LLC | 12,295 | +12,295 | $97.7K | +$97.7K | — |
| ProShare Advisors LLC | 11,780 | +11,780 | $93.7K | +$93.7K | — |
| SageView Advisory Group, LLC | 3,000 | +3,000 | $23.9K | +$23.9K | — |
| STRS OHIO | 2,800 | +2,800 | $22.3K | +$22.3K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 607 | +607 | $4.8K | +$4.8K | — |
| Torren Management, LLC | 70 | +70 | $557 | +$557 | — |
| IFP Advisors, Inc | 34 | +34 | $275 | +$275 | — |
| SkyView Investment Advisors, LLC | 24,000 | +24,000 | $191 | +$191 | — |
| Allworth Financial LP | 15 | +15 | $120 | +$120 | — |
| FNY Investment Advisers, LLC | 69 | +69 | $0 | $0 | — |
Added To(42)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 6,175,331 | +2,448,880 | $49.1M | +$18.4M | 65.7% |
| MORGAN STANLEY | 1,829,252 | +587,258 | $14.5M | +$4.3M | 47.3% |
| MILLENNIUM MANAGEMENT LLC | 3,176,390 | +604,121 | $25.3M | +$4.1M | 23.5% |
| STEMPOINT CAPITAL LP | 287,689 | +205,831 | $2.3M | +$1.6M | 251.4% |
| D. E. Shaw & Co., Inc. | 381,763 | +208,561 | $3.0M | +$1.6M | 120.4% |
| BlackRock, Inc. | 3,069,844 | +295,572 | $24.4M | +$1.6M | 10.7% |
| Hennion & Walsh Asset Management, Inc. | 308,509 | +199,528 | $2.5M | +$1.6M | 183.1% |
| GOLDMAN SACHS GROUP INC | 456,744 | +196,525 | $3.6M | +$1.5M | 75.5% |
| UBS Group AG | 222,015 | +140,422 | $1.8M | +$1.1M | 172.1% |
| BNP PARIBAS ARBITRAGE, SNC | 127,999 | +119,062 | $1.0M | +$944.0K | 1332.2% |
| Woodline Partners LP | 300,323 | +100,000 | $2.4M | +$738.9K | 49.9% |
| Erste Asset Management GmbH | 789,702 | +80,000 | $6.3M | +$420.3K | 11.3% |
| ExodusPoint Capital Management, LP | 86,926 | +43,953 | $691.1K | +$337.4K | 102.3% |
| Privium Fund Management B.V. | 200,000 | +37,000 | $1.6M | +$248.5K | 22.7% |
| STATE STREET CORP | 729,445 | +48,414 | $5.8M | +$194.2K | 7.1% |
| WELLS FARGO & COMPANY/MN | 49,788 | +22,481 | $395.8K | +$171.1K | 82.3% |
| Invesco Ltd. | 90,881 | +21,381 | $722.5K | +$150.5K | 30.8% |
| JANE STREET GROUP, LLC | 125,242 | +20,749 | $995.7K | +$135.7K | 19.9% |
| VANGUARD GROUP INC | 494,753 | +30,818 | $3.9M | +$115.1K | 6.6% |
| DAVENPORT & Co LLC | 69,200 | +14,000 | $550.1K | +$95.8K | 25.4% |
| Russell Investments Group, Ltd. | 95,719 | +12,875 | $761.0K | +$79.2K | 15.5% |
| FMR LLC | 13,825 | +8,301 | $109.9K | +$64.4K | 150.3% |
| DEUTSCHE BANK AG\ | 40,711 | +7,390 | $323.7K | +$49.4K | 22.2% |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | 66,400 | +7,200 | $527.9K | +$40.7K | 12.2% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 111,422 | +7,363 | $885.8K | +$29.4K | 7.1% |
| AQR CAPITAL MANAGEMENT LLC | 108,014 | +230 | $858.7K | -$28.4K | 0.2% |
| BANK OF AMERICA CORP /DE/ | 208,454 | +10,248 | $1.7M | +$26.0K | 5.2% |
| XTX Topco Ltd | 38,030 | +3,766 | $302.3K | +$20.3K | 11.0% |
| BARCLAYS PLC | 108,110 | +24,109 | $704.9K | +$13.6K | 28.7% |
| CITIGROUP INC | 15,552 | +2,138 | $123.6K | +$13.2K | 15.9% |
| Quantinno Capital Management LP | 60,756 | +3,523 | $483.0K | +$12.0K | 6.2% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 21,006 | +1,968 | $167.0K | +$10.3K | 10.3% |
| GEODE CAPITAL MANAGEMENT, LLC | 573,783 | +18,470 | $4.6M | -$8.7K | 3.3% |
| KENNEDY CAPITAL MANAGEMENT LLC | 70,738 | +1,495 | $562.4K | -$7.5K | 2.1% |
| Mirae Asset Global Investments Co., Ltd. | 3,911 | +801 | $31.1K | +$5.5K | 25.8% |
| Rockefeller Capital Management L.P. | 6,130 | +630 | $48.7K | +$3.5K | 11.4% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,785 | +190 | $22.1K | +$784 | 7.3% |
| Sterling Capital Management LLC | 940 | +126 | $7.5K | +$774 | 15.5% |
| Tower Research Capital LLC (TRC) | 1,514 | +12 | $12.0K | -$325 | 0.8% |
| PNC Financial Services Group, Inc. | 80 | +12 | $636 | +$76 | 17.6% |
| GAMMA Investing LLC | 375 | +18 | $3.0K | +$43 | 5.0% |
| ROTHSCHILD INVESTMENT LLC | 185 | +5 | $1.5K | -$10 | 2.8% |
Reduced(63)
Sold Out(14)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Qube Research & Technologies Ltd | 0 | -115,051 | $0 | -$946.9K | — |
| AMH Equity Ltd | 0 | -80,000 | $0 | -$658.4K | — |
| Dynamic Technology Lab Private Ltd | 0 | -45,417 | $0 | -$374.0K | — |
| Sender Co & Partners, Inc. | 0 | -40,668 | $0 | -$334.7K | — |
| CIBC Bancorp USA Inc. | 0 | -38,614 | $0 | -$317.8K | — |
| FRANKLIN RESOURCES INC | 0 | -26,406 | $0 | -$217.3K | — |
| HSBC HOLDINGS PLC | 0 | -19,143 | $0 | -$158.1K | — |
| Family Management Corp | 0 | -10,000 | $0 | -$82.3K | — |
| SRS Capital Advisors, Inc. | 0 | -4,283 | $0 | -$35.2K | — |
| GROUP ONE TRADING, L.P. | 0 | -200 | $0 | -$1.6K | — |
| Bell Investment Advisors, Inc | 0 | -100 | $0 | -$823 | — |
| Founders Capital Management | 0 | -50 | $0 | -$412 | — |
| Clearstead Advisors, LLC | 0 | -40 | $0 | -$330 | — |
| GSA CAPITAL PARTNERS LLP | 0 | -24,660 | $0 | -$203 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Sanofi | 12,197,737 | $97.0M | 0 | 0.0% |
| PERCEPTIVE ADVISORS LLC | 10,326,103 | $82.1M | -2,300,000 | -18.2% |
| JOHNSON & JOHNSON | 6,641,064 | $52.8M | 0 | 0.0% |
| Rubric Capital Management LP | 6,175,331 | $49.1M | +2,448,880 | 65.7% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4,000,000 | $31.8M | -184,578 | -4.4% |
| Prosight Management, LP | 3,209,788 | $25.5M | -879,721 | -21.5% |
| MILLENNIUM MANAGEMENT LLC | 3,176,390 | $25.3M | +604,121 | 23.5% |
| BlackRock, Inc. | 3,069,844 | $24.4M | +295,572 | 10.7% |
| 683 Capital Management, LLC | 2,559,082 | $20.3M | -65,918 | -2.5% |
| MORGAN STANLEY | 1,829,252 | $14.5M | +587,258 | 47.3% |
| Knoll Capital Management, LLC | 1,250,000 | $9.9M | 0 | 0.0% |
| Erste Asset Management GmbH | 789,702 | $6.3M | +80,000 | 11.3% |
| STATE STREET CORP | 729,445 | $5.8M | +48,414 | 7.1% |
| 22NW, LP | 586,519 | $4.7M | 0 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 573,783 | $4.6M | +18,470 | 3.3% |
| Long Focus Capital Management, LLC | 524,745 | $4.2M | 0 | 0.0% |
| VANGUARD GROUP INC | 494,753 | $3.9M | +30,818 | 6.6% |
| GOLDMAN SACHS GROUP INC | 456,744 | $3.6M | +196,525 | 75.5% |
| Opaleye Management Inc. | 390,844 | $3.1M | +390,844 | — |
| D. E. Shaw & Co., Inc. | 381,763 | $3.0M | +208,561 | 120.4% |
New & Closed Positions this quarter
Closed Positions
14 managers exited
Top five by prior-quarter value
- Qube Research & Technologies Ltd$946.9K
- AMH Equity Ltd$658.4K
- Dynamic Technology Lab Private Ltd$374.0K
- Sender Co & Partners, Inc.$334.7K
- CIBC Bancorp USA Inc.$317.8K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for MGTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.