New Positions
21 managers initiated
Top five by reported value
Inovio Pharmaceuticals Inc NASDAQ NMS - GLOBAL MARKET:INO
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
21 new28 added52 reduced19 exited
Total Institutional Holders
101
as of 2025-12-31
Top Holder
FMR LLC
$17.1M
Largest QoQ Increase
FMR LLC
+9,845,363 sh
Largest QoQ Decrease
ADAGE CAPITAL PARTNERS GP, L.L.C.
-875,000 sh
New Positions(21)
Added To(28)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| FMR LLC | 9,846,664 | +9,845,363 | $17.1M | +$17.1M | 756753.5% |
| Boxer Capital Management, LLC | 4,720,122 | +2,420,122 | $9.6M | +$4.2M | 105.2% |
| D. E. Shaw & Co., Inc. | 2,231,811 | +1,425,069 | $3.9M | +$2.0M | 176.6% |
| JANUS HENDERSON GROUP PLC | 3,308,406 | +42,146 | $5.8M | -$1.9M | 1.3% |
| VANGUARD GROUP INC | 3,315,580 | +602,708 | $5.8M | -$579.0K | 22.2% |
| CITADEL ADVISORS LLC | 429,100 | +285,098 | $746.6K | +$409.7K | 198.0% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 130,792 | +113,119 | $227.6K | +$186.2K | 640.1% |
| Qube Research & Technologies Ltd | 115,470 | +81,974 | $200.9K | +$122.5K | 244.7% |
| TWO SIGMA INVESTMENTS, LP | 322,739 | +31,939 | $561.6K | -$118.9K | 11.0% |
| BlackRock, Inc. | 617,869 | +118,466 | $1.1M | -$93.5K | 23.7% |
| CIBC Private Wealth Group, LLC | 50,000 | +49,986 | $87.0K | +$87.0K | 357042.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 769,356 | +222,609 | $1.3M | +$60.0K | 40.7% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 363,050 | +111,668 | $631.7K | +$43.5K | 44.4% |
| JANE STREET GROUP, LLC | 75,789 | +3,983 | $131.9K | -$36.2K | 5.5% |
| NORTHERN TRUST CORP | 299,984 | +61,513 | $522.0K | -$36.0K | 25.8% |
| Caitong International Asset Management Co., Ltd | 20,572 | +18,160 | $35.8K | +$30.2K | 752.9% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 179 | +178 | $29.0K | +$29.0K | 17800.0% |
| Quadrature Capital Ltd | 37,222 | +107 | $64.8K | -$22.1K | 0.3% |
| Green Alpha Advisors, LLC | 72,095 | +24,007 | $125.4K | +$12.9K | 49.9% |
| RAYMOND JAMES FINANCIAL INC | 16,688 | +8 | $29.0K | -$10.0K | 0.0% |
| STATE STREET CORP | 247,410 | +61,200 | $430.5K | -$5.2K | 32.9% |
| STEPHENS INC /AR/ | 15,500 | +2,000 | $27.0K | -$4.6K | 14.8% |
| WELLS FARGO & COMPANY/MN | 2,744 | +2,528 | $4.8K | +$4.3K | 1170.4% |
| MJT & Associates Financial Advisory Group, Inc. | 650 | +325 | $1.1K | +$371 | 100.0% |
| GSA CAPITAL PARTNERS LLP | 459,828 | +16,724 | $800 | -$237 | 3.8% |
| BARCLAYS PLC | 82 | +81 | $167 | +$165 | 8100.0% |
| NATIONAL BANK OF CANADA /FI/ | 99 | +58 | $172 | +$76 | 141.5% |
| Greenwich Wealth Management LLC | 23,999 | +3,600 | $42 | -$6 | 17.6% |
Reduced(52)
Sold Out(19)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GMT CAPITAL CORP | 0 | -126,119 | $0 | -$295.1K | — |
| Headlands Technologies LLC | 0 | -110,068 | $0 | -$257.6K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -42,300 | $0 | -$194.2K | — |
| DIMENSIONAL FUND ADVISORS LP | 0 | -37,991 | $0 | -$89.1K | — |
| ZACKS INVESTMENT MANAGEMENT | 0 | -19,455 | $0 | -$45.5K | — |
| Focus Partners Wealth | 0 | -14,289 | $0 | -$33.4K | — |
| CITIGROUP INC | 0 | -12,977 | $0 | -$30.4K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -12,330 | $0 | -$28.9K | — |
| Meridian Wealth Management, LLC | 0 | -10,000 | $0 | -$23.4K | — |
| Keystone Financial Group | 0 | -10,073 | $0 | -$20.5K | — |
| CROWLEY WEALTH MANAGEMENT, INC. | 0 | -404 | $0 | -$945 | — |
| PRINCIPAL SECURITIES, INC. | 0 | -177 | $0 | -$414 | — |
| HRT FINANCIAL LP | 0 | -65,065 | $0 | -$152 | — |
| Strategic Wealth Partners, Ltd. | 0 | -29 | $0 | -$68 | — |
| Optiver Holding B.V. | 0 | -24 | $0 | -$56 | — |
| Groupe la Francaise | 0 | -20 | $0 | -$42 | — |
| Wealthspire Advisors, LLC | 0 | -15 | $0 | -$36 | — |
| SG Americas Securities, LLC | 0 | -11,497 | $0 | -$27 | — |
| Johnson Financial Group, Inc. | 0 | -4 | $0 | -$10 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| FMR LLC | 9,846,664 | $17.1M | +9,845,363 | 756753.5% |
| Boxer Capital Management, LLC | 4,720,122 | $9.6M | +2,420,122 | 105.2% |
| JANUS HENDERSON GROUP PLC | 3,308,406 | $5.8M | +42,146 | 1.3% |
| VANGUARD GROUP INC | 3,315,580 | $5.8M | +602,708 | 22.2% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,553,571 | $4.4M | -875,000 | -25.5% |
| D. E. Shaw & Co., Inc. | 2,231,811 | $3.9M | +1,425,069 | 176.6% |
| ADAR1 Capital Management, LLC | 1,560,508 | $2.7M | +1,560,508 | — |
| MILLENNIUM MANAGEMENT LLC | 1,403,379 | $2.4M | -569,139 | -28.9% |
| GEODE CAPITAL MANAGEMENT, LLC | 769,356 | $1.3M | +222,609 | 40.7% |
| DIADEMA PARTNERS LP | 633,682 | $1.1M | +633,682 | — |
| BlackRock, Inc. | 617,869 | $1.1M | +118,466 | 23.7% |
| RENAISSANCE TECHNOLOGIES LLC | 553,164 | $962.5K | -263,175 | -32.2% |
| CITADEL ADVISORS LLC | 429,100 | $746.6K | +285,098 | 198.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 363,050 | $631.7K | +111,668 | 44.4% |
| TWO SIGMA INVESTMENTS, LP | 322,739 | $561.6K | +31,939 | 11.0% |
| NORTHERN TRUST CORP | 299,984 | $522.0K | +61,513 | 25.8% |
| 683 Capital Management, LLC | 248,790 | $432.9K | +248,790 | — |
| STATE STREET CORP | 247,410 | $430.5K | +61,200 | 32.9% |
| OMERS ADMINISTRATION Corp | 223,000 | $388.0K | +223,000 | — |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 173,000 | $301.0K | +173,000 | — |
New & Closed Positions this quarter
Closed Positions
19 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for INO against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.