New Positions
18 managers initiated
Top five by reported value
Shattuck Labs Inc NASDAQ NMS - GLOBAL MARKET:STTK
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
18 new19 added29 reduced9 exited
Total Institutional Holders
66
as of 2025-12-31
Top Holder
ORBIMED ADVISORS LLC
$23.0M
Largest QoQ Increase
NEXTBio Capital Management LP
+3,149,907 sh
Largest QoQ Decrease
Prosight Management, LP
-3,069,693 sh
New Positions(18)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| NEXTBio Capital Management LP | 3,149,907 | +3,149,907 | $11.5M | +$11.5M | — |
| Point72 Asset Management, L.P. | 1,068,231 | +1,068,231 | $3.9M | +$3.9M | — |
| TD Asset Management Inc | 251,050 | +251,050 | $916.3K | +$916.3K | — |
| SPHERA FUNDS MANAGEMENT LTD. | 195,212 | +195,212 | $712.5K | +$712.5K | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 135,056 | +135,056 | $486.2K | +$486.2K | — |
| Connor, Clark & Lunn Investment Management Ltd. | 65,734 | +65,734 | $239.9K | +$239.9K | — |
| EP Wealth Advisors, LLC | 41,167 | +41,167 | $150.3K | +$150.3K | — |
| Invesco Ltd. | 28,231 | +28,231 | $103.0K | +$103.0K | — |
| OMERS ADMINISTRATION Corp | 26,500 | +26,500 | $96.7K | +$96.7K | — |
| DIMENSIONAL FUND ADVISORS LP | 23,192 | +23,192 | $84.7K | +$84.7K | — |
| Mallini Complete Financial Planning LLC | 22,632 | +22,632 | $82.6K | +$82.6K | — |
| AMERICAN CENTURY COMPANIES INC | 17,282 | +17,282 | $63.1K | +$63.1K | — |
| Keel Point, LLC | 14,270 | +14,270 | $52.1K | +$52.1K | — |
| AMERIPRISE FINANCIAL INC | 11,500 | +11,500 | $42.0K | +$42.0K | — |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,926,140 | +1,926,140 | $7.0K | +$7.0K | — |
| T. Rowe Price Investment Management, Inc. | 1,354,761 | +1,354,761 | $4.9K | +$4.9K | — |
| BARCLAYS PLC | 2,114 | +2,114 | $1.7K | +$1.7K | — |
| STONERIDGE INVESTMENT PARTNERS LLC | 10,453 | +10,453 | $38 | +$38 | — |
Added To(19)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 2,377,746 | +249,345 | $8.7M | +$3.6M | 11.7% |
| abrdn plc | 531,177 | +436,673 | $1.9M | +$1.7M | 462.1% |
| FMR LLC | 392,600 | +389,233 | $1.4M | +$1.4M | 11560.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 618,277 | +150,318 | $2.3M | +$1.1M | 32.1% |
| RENAISSANCE TECHNOLOGIES LLC | 340,700 | +123,833 | $1.2M | +$725.2K | 57.1% |
| TWO SIGMA INVESTMENTS, LP | 437,729 | +29,131 | $1.6M | +$621.2K | 7.1% |
| BlackRock, Inc. | 418,529 | +7,237 | $1.5M | +$544.6K | 1.8% |
| GOLDMAN SACHS GROUP INC | 128,165 | +111,365 | $467.8K | +$427.6K | 662.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 148,427 | +80,311 | $541.8K | +$379.0K | 117.9% |
| STATE STREET CORP | 215,418 | +38,700 | $786.3K | +$363.9K | 21.9% |
| TWO SIGMA ADVISERS, LP | 170,600 | +57,923 | $622.7K | +$353.4K | 51.4% |
| NORTHERN TRUST CORP | 145,445 | +54,173 | $530.9K | +$312.7K | 59.4% |
| CITADEL ADVISORS LLC | 68,846 | +46,646 | $251.3K | +$198.2K | 210.1% |
| Squarepoint Ops LLC | 64,785 | +45,525 | $236.5K | +$190.4K | 236.4% |
| Qube Research & Technologies Ltd | 38,757 | +22,806 | $141.5K | +$103.3K | 143.0% |
| CITIGROUP INC | 24,832 | +9,724 | $90.6K | +$54.5K | 64.4% |
| UBS Group AG | 13,204 | +11,771 | $48.2K | +$44.8K | 821.4% |
| MORGAN STANLEY | 18,108 | +1,457 | $66.1K | +$26.3K | 8.8% |
| JPMORGAN CHASE & CO | 343 | +40 | $1.3K | +$528 | 13.2% |
Reduced(29)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 6,306,127 | 0 | $23.0M | +$7.9M | 0.0% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 6,306,127 | 0 | $23.0M | +$7.9M | 0.0% |
| Redmile Group, LLC | 5,539,724 | 0 | $20.2M | +$7.0M | 0.0% |
| Prosight Management, LP | 2,381,502 | -3,069,693 | $8.7M | -$4.3M | -56.3% |
| CLARK ESTATES INC/NY | 1,475,648 | 0 | $5.4M | +$1.9M | 0.0% |
| PINNACLE ASSOCIATES LTD | 1,350,638 | -38,085 | $4.9M | +$1.6M | -2.7% |
| 683 Capital Management, LLC | 1,390,000 | -142,216 | $5.1M | +$1.4M | -9.3% |
| BANK OF AMERICA CORP /DE/ | 1,106,617 | -25,271 | $4.0M | +$1.3M | -2.2% |
| MARSHALL WACE, LLP | 489,912 | -166,741 | $1.8M | +$218.8K | -25.4% |
| Pathstone Holdings, LLC | 157,083 | 0 | $573.4K | +$197.9K | 0.0% |
| Bank of New York Mellon Corp | 110,394 | 0 | $402.9K | +$139.1K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 477,408 | -213,493 | $1.7M | +$91.3K | -30.9% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 42,300 | 0 | $154.4K | +$53.3K | 0.0% |
| PIPER SANDLER & CO. | 39,467 | 0 | $144.1K | +$49.7K | 0.0% |
| JANE STREET GROUP, LLC | 54,046 | -45,001 | $197.3K | -$39.5K | -45.4% |
| RITHOLTZ WEALTH MANAGEMENT | 26,000 | 0 | $94.9K | +$32.8K | 0.0% |
| XTX Topco Ltd | 24,873 | -1,353 | $90.8K | +$28.1K | -5.2% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 20,881 | 0 | $76.2K | +$26.3K | 0.0% |
| CHOREO, LLC | 27,251 | 0 | $76.5K | +$22.9K | 0.0% |
| PRUDENTIAL FINANCIAL INC | 17,700 | 0 | $64.6K | +$22.3K | 0.0% |
| Engineers Gate Manager LP | 13,670 | 0 | $49.9K | +$17.2K | 0.0% |
| Creative Planning | 12,335 | 0 | $45.0K | +$15.5K | 0.0% |
| Royal Bank of Canada | 64 | -6,965 | $0 | -$7.0K | -99.1% |
| ACADIAN ASSET MANAGEMENT LLC | 79,367 | -249,921 | $289 | -$496 | -75.9% |
| BNP PARIBAS ARBITRAGE, SNC | 540 | -418 | $2.0K | -$319 | -43.6% |
| SBI Securities Co., Ltd. | 92 | 0 | $336 | +$116 | 0.0% |
| LBJ Family Wealth Advisors, Ltd. | 82,177 | 0 | $300 | +$104 | 0.0% |
| Optiver Holding B.V. | 66 | 0 | $241 | +$83 | 0.0% |
| CWM, LLC | 43 | -84 | $0 | $0 | -66.1% |
Sold Out(9)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| TAKEDA PHARMACEUTICAL CO LTD | 0 | -515,619 | $0 | -$1.2M | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -43,500 | $0 | -$134.7K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -14,454 | $0 | -$34.5K | — |
| Turtle Creek Wealth Advisors, LLC | 0 | -12,235 | $0 | -$29.2K | — |
| AssuredPartners Investment Advisors, LLC | 0 | -10,000 | $0 | -$23.9K | — |
| Cubist Systematic Strategies, LLC | 0 | -8,863 | $0 | -$21.2K | — |
| Point72 (DIFC) Ltd | 0 | -370 | $0 | -$884 | — |
| Virtu Financial LLC | 0 | -16,054 | $0 | -$38 | — |
| SRS Capital Advisors, Inc. | 0 | -14 | $0 | -$33 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 6,306,127 | $23.0M | 0 | 0.0% |
| ORBIMED ADVISORS LLC | 6,306,127 | $23.0M | 0 | 0.0% |
| Redmile Group, LLC | 5,539,724 | $20.2M | 0 | 0.0% |
| NEXTBio Capital Management LP | 3,149,907 | $11.5M | +3,149,907 | — |
| Prosight Management, LP | 2,381,502 | $8.7M | -3,069,693 | -56.3% |
| VANGUARD GROUP INC | 2,377,746 | $8.7M | +249,345 | 11.7% |
| CLARK ESTATES INC/NY | 1,475,648 | $5.4M | 0 | 0.0% |
| 683 Capital Management, LLC | 1,390,000 | $5.1M | -142,216 | -9.3% |
| PINNACLE ASSOCIATES LTD | 1,350,638 | $4.9M | -38,085 | -2.7% |
| BANK OF AMERICA CORP /DE/ | 1,106,617 | $4.0M | -25,271 | -2.2% |
| Point72 Asset Management, L.P. | 1,068,231 | $3.9M | +1,068,231 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 618,277 | $2.3M | +150,318 | 32.1% |
| abrdn plc | 531,177 | $1.9M | +436,673 | 462.1% |
| MARSHALL WACE, LLP | 489,912 | $1.8M | -166,741 | -25.4% |
| MILLENNIUM MANAGEMENT LLC | 477,408 | $1.7M | -213,493 | -30.9% |
| TWO SIGMA INVESTMENTS, LP | 437,729 | $1.6M | +29,131 | 7.1% |
| BlackRock, Inc. | 418,529 | $1.5M | +7,237 | 1.8% |
| FMR LLC | 392,600 | $1.4M | +389,233 | 11560.2% |
| RENAISSANCE TECHNOLOGIES LLC | 340,700 | $1.2M | +123,833 | 57.1% |
| TD Asset Management Inc | 251,050 | $916.3K | +251,050 | — |
New & Closed Positions this quarter
Closed Positions
9 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for STTK against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.