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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · SRZNW

Surrozen, Inc. NCM:SRZNW

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

26 new16 added12 reduced7 exited

New Positions(26)

ManagerSharesΔ SharesValueΔ Value% Δ
Spruce Street Capital LP432,040+432,040$9.8M+$9.8M
Boxer Capital Management, LLC416,150+416,150$9.4M+$9.4M
SILVERARC CAPITAL MANAGEMENT, LLC157,323+157,323$3.6M+$3.6M
Empery Asset Management, LP103,974+103,974$2.3M+$2.3M
FRED ALGER MANAGEMENT, LLC99,560+99,560$2.3M+$2.3M
Kalehua Capital Management LLC385,178+385,178$1.9M+$1.9M
Ikarian Capital, LLC65,788+65,788$1.5M+$1.5M
AMERIPRISE FINANCIAL INC65,688+65,688$1.5M+$1.5M
683 Capital Management, LLC41,999+41,999$949.2K+$949.2K
Walleye Capital LLC41,041+41,041$927.5K+$927.5K
JANE STREET GROUP, LLC27,622+27,622$624.3K+$624.3K
GOLDMAN SACHS GROUP INC25,823+25,823$583.6K+$583.6K
LMR Partners LLP23,557+23,557$532.4K+$532.4K
Brevan Howard Capital Management LP18,921+18,921$427.6K+$427.6K
BOOTHBAY FUND MANAGEMENT, LLC18,307+18,307$413.7K+$413.7K
Quadrature Capital Ltd14,802+14,802$334.5K+$334.5K
OMERS ADMINISTRATION Corp13,700+13,700$309.6K+$309.6K
NORTHERN TRUST CORP13,530+13,530$305.8K+$305.8K
IEQ CAPITAL, LLC13,471+13,471$304.4K+$304.4K
MARSHALL WACE, LLP10,939+10,939$247.2K+$247.2K
Persistent Asset Partners Ltd4,359+4,359$98.5K+$98.5K
BNP PARIBAS ARBITRAGE, SNC2,520+2,520$57.0K+$57.0K
CITIGROUP INC1,062+1,062$24.0K+$24.0K
UBS Group AG59+59$1.3K+$1.3K
Royal Bank of Canada65+65$1.0K+$1.0K
ACADIAN ASSET MANAGEMENT LLC1,508+1,508$34+$34

Added To(16)

ManagerSharesΔ SharesValueΔ Value% Δ
MILLENNIUM MANAGEMENT LLC721,266+611,497$16.3M+$14.9M557.1%
BRAIDWELL LP470,000+330,000$10.6M+$8.8M235.7%
5AM Venture Management, LLC387,500+77,500$8.8M+$4.8M25.0%
Woodline Partners LP230,572+182,379$5.2M+$4.6M378.4%
VANGUARD GROUP INC319,236+52,818$7.2M+$3.8M19.8%
Balyasny Asset Management LLC190,489+119,757$4.3M+$3.4M169.3%
Eversept Partners, LP95,286+18,289$2.2M+$1.2M23.8%
GEODE CAPITAL MANAGEMENT, LLC66,995+12,468$1.5M+$811.7K22.9%
Schonfeld Strategic Advisors LLC74,645+5,621$1.7M+$797.6K8.1%
BANK OF AMERICA CORP /DE/29,608+29,602$669.1K+$669.1K493366.7%
BlackRock, Inc.26,118+12,375$590.3K+$413.2K90.0%
MORGAN STANLEY36,961+2,197$835.3K+$387.4K6.3%
STATE STREET CORP24,326+11,000$549.8K+$378.1K82.5%
RENAISSANCE TECHNOLOGIES LLC22,626+7,900$511.3K+$321.6K53.6%
CITADEL ADVISORS LLC14,740+865$333.1K+$154.3K6.2%
China Universal Asset Management Co., Ltd.1,500+500$33.9K+$21.0K50.0%

Reduced(12)

ManagerSharesΔ SharesValueΔ Value% Δ
VR Adviser, LLC632,9310$14.3M+$6.1M0.0%
STEMPOINT CAPITAL LP619,766-93,697$12.7M+$3.5M-13.1%
Vivo Capital, LLC260,0000$5.9M+$2.5M0.0%
Nantahala Capital Management, LLC229,5270$5.2M+$2.2M0.0%
ACUTA CAPITAL PARTNERS, LLC178,4150$4.0M+$1.7M0.0%
REGENTS OF THE UNIVERSITY OF CALIFORNIA133,2070$3.0M+$1.3M0.0%
ADAGE CAPITAL PARTNERS GP, L.L.C.88,6530$2.0M+$861.3K0.0%
Euclidean Capital LLC87,6960$2.0M+$852.0K0.0%
Stonepine Capital Management, LLC113,631-136,515$2.6M-$655.1K-54.6%
ArrowMark Colorado Holdings LLC55,1230$1.2M+$535.5K0.0%
Alyeska Investment Group, L.P.10,1880$230.2K+$99.0K0.0%
PRICE T ROWE ASSOCIATES INC /MD/21,7150$491+$2110.0%

Sold Out(7)

ManagerSharesΔ SharesValueΔ Value% Δ
RA CAPITAL MANAGEMENT, L.P.0-602,626$0-$7.8M
Samsara BioCapital, LLC0-241,400$0-$3.1M
Board of Trustees of The Leland Stanford Junior University0-52,130$0-$671.7K
Trustees of Columbia University in the City of New York0-47,930$0-$617.6K
WOLVERINE ASSET MANAGEMENT LLC0-281$0-$3.6K
BARCLAYS PLC0-13$0-$168
SBI Securities Co., Ltd.0-2$0-$26

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
MILLENNIUM MANAGEMENT LLC721,266$16.3M+611,497557.1%
VR Adviser, LLC632,931$14.3M00.0%
STEMPOINT CAPITAL LP619,766$12.7M-93,697-13.1%
BRAIDWELL LP470,000$10.6M+330,000235.7%
Spruce Street Capital LP432,040$9.8M+432,040
Boxer Capital Management, LLC416,150$9.4M+416,150
5AM Venture Management, LLC387,500$8.8M+77,50025.0%
VANGUARD GROUP INC319,236$7.2M+52,81819.8%
Vivo Capital, LLC260,000$5.9M00.0%
Woodline Partners LP230,572$5.2M+182,379378.4%
Nantahala Capital Management, LLC229,527$5.2M00.0%
Balyasny Asset Management LLC190,489$4.3M+119,757169.3%
ACUTA CAPITAL PARTNERS, LLC178,415$4.0M00.0%
SILVERARC CAPITAL MANAGEMENT, LLC157,323$3.6M+157,323
REGENTS OF THE UNIVERSITY OF CALIFORNIA133,207$3.0M00.0%
Stonepine Capital Management, LLC113,631$2.6M-136,515-54.6%
Empery Asset Management, LP103,974$2.3M+103,974
FRED ALGER MANAGEMENT, LLC99,560$2.3M+99,560
Eversept Partners, LP95,286$2.2M+18,28923.8%
ADAGE CAPITAL PARTNERS GP, L.L.C.88,653$2.0M00.0%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for SRZNW against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.