New Positions
5 managers initiated
Top five by reported value
enVVeno Medical Corp NASDAQ NMS - GLOBAL MARKET:NVNO
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
5 new10 added22 reduced4 exited
Total Institutional Holders
37
as of 2025-12-31
Top Holder
PERCEPTIVE ADVISORS LLC
$564.3K
Largest QoQ Increase
CM Management, LLC
+650,000 sh
Largest QoQ Decrease
VANGUARD GROUP INC
-561,945 sh
New Positions(5)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Sanctuary Advisors, LLC | 36,000 | +36,000 | $111.0K | +$111.0K | — |
| TWO SIGMA INVESTMENTS, LP | 159,619 | +159,619 | $51.2K | +$51.2K | — |
| ACT CAPITAL MANAGEMENT, LLC | 115,000 | +115,000 | $36.9K | +$36.9K | — |
| TWO SIGMA ADVISERS, LP | 14,000 | +14,000 | $4.5K | +$4.5K | — |
| Virtu Financial LLC | 73,878 | +73,878 | $24 | +$24 | — |
Added To(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CM Management, LLC | 1,250,000 | +650,000 | $401.0K | -$142.7K | 108.3% |
| BlackRock, Inc. | 60,474 | +617 | $19.4K | -$34.8K | 1.0% |
| SIMPLEX TRADING, LLC | 93,082 | +79,331 | $29.9K | +$29.9K | 576.9% |
| XTX Topco Ltd | 67,187 | +25,145 | $21.6K | -$16.5K | 59.8% |
| RENAISSANCE TECHNOLOGIES LLC | 51,300 | +22,100 | $16.5K | -$10.0K | 75.7% |
| JANE STREET GROUP, LLC | 178,855 | +107,084 | $57.4K | -$7.7K | 149.2% |
| TWO SIGMA SECURITIES, LLC | 62,582 | +48,471 | $20.1K | +$7.3K | 343.5% |
| UBS Group AG | 32,121 | +21,851 | $10.3K | +$1.0K | 212.8% |
| GROUP ONE TRADING, L.P. | 1,735 | +1,533 | $557 | +$374 | 758.9% |
| GSA CAPITAL PARTNERS LLP | 198,592 | +185,172 | $64 | +$52 | 1379.8% |
Reduced(22)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 1,759,035 | 0 | $564.3K | -$1.0M | 0.0% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,265,845 | -93,416 | $406.1K | -$825.5K | -6.9% |
| VANGUARD GROUP INC | 299,246 | -561,945 | $96.1K | -$684.2K | -65.3% |
| Westside Investment Management, Inc. | 92,650 | -120,150 | $29.7K | -$163.1K | -56.5% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 132,325 | -70,046 | $42.5K | -$141.1K | -34.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 201,244 | 0 | $64.6K | -$117.8K | 0.0% |
| JPMORGAN CHASE & CO | 182,303 | -19 | $58.5K | -$106.7K | -0.0% |
| BANK OF AMERICA CORP /DE/ | 2,026 | -65,894 | $648 | -$60.9K | -97.0% |
| CITADEL ADVISORS LLC | 53,826 | -12,985 | $17.3K | -$43.3K | -19.4% |
| Creative Planning | 20,905 | -17,390 | $6.7K | -$28.0K | -45.4% |
| STATE STREET CORP | 40,800 | 0 | $13.1K | -$23.9K | 0.0% |
| Fermata Advisors, LLC | 32,717 | -4,732 | $10.5K | -$23.4K | -12.6% |
| NORTHERN TRUST CORP | 38,081 | 0 | $12.2K | -$22.3K | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 20,905 | -1,927 | $6.7K | -$14.0K | -8.4% |
| MORGAN STANLEY | 2,874 | -846 | $922 | -$2.4K | -22.7% |
| WELLS FARGO & COMPANY/MN | 2,000 | 0 | $642 | -$1.2K | 0.0% |
| WOLVERINE ASSET MANAGEMENT LLC | 1,768 | 0 | $567 | -$1.0K | 0.0% |
| CIBC Private Wealth Group, LLC | 860 | 0 | $276 | -$503 | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 250 | 0 | $80 | -$152 | 0.0% |
| HRT FINANCIAL LP | 49,234 | -5,901 | $15 | -$34 | -10.7% |
| JONES FINANCIAL COMPANIES LLLP | 20 | 0 | $6 | -$13 | 0.0% |
| Cambridge Investment Research Advisors, Inc. | 10,001 | 0 | $3 | -$6 | 0.0% |
Sold Out(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MARSHALL WACE, LLP | 0 | -39,883 | $0 | -$36.3K | — |
| WOLVERINE TRADING, LLC | 0 | -18,339 | $0 | -$17.2K | — |
| Tamar Securities, LLC | 0 | -13,990 | $0 | -$12.7K | — |
| Avion Wealth | 0 | -2,000 | $0 | -$1 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 1,759,035 | $564.3K | 0 | 0.0% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,265,845 | $406.1K | -93,416 | -6.9% |
| CM Management, LLC | 1,250,000 | $401.0K | +650,000 | 108.3% |
| Sanctuary Advisors, LLC | 36,000 | $111.0K | +36,000 | — |
| VANGUARD GROUP INC | 299,246 | $96.1K | -561,945 | -65.3% |
| GEODE CAPITAL MANAGEMENT, LLC | 201,244 | $64.6K | 0 | 0.0% |
| JPMORGAN CHASE & CO | 182,303 | $58.5K | -19 | -0.0% |
| JANE STREET GROUP, LLC | 178,855 | $57.4K | +107,084 | 149.2% |
| TWO SIGMA INVESTMENTS, LP | 159,619 | $51.2K | +159,619 | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 132,325 | $42.5K | -70,046 | -34.6% |
| ACT CAPITAL MANAGEMENT, LLC | 115,000 | $36.9K | +115,000 | — |
| SIMPLEX TRADING, LLC | 93,082 | $29.9K | +79,331 | 576.9% |
| Westside Investment Management, Inc. | 92,650 | $29.7K | -120,150 | -56.5% |
| XTX Topco Ltd | 67,187 | $21.6K | +25,145 | 59.8% |
| TWO SIGMA SECURITIES, LLC | 62,582 | $20.1K | +48,471 | 343.5% |
| BlackRock, Inc. | 60,474 | $19.4K | +617 | 1.0% |
| CITADEL ADVISORS LLC | 53,826 | $17.3K | -12,985 | -19.4% |
| RENAISSANCE TECHNOLOGIES LLC | 51,300 | $16.5K | +22,100 | 75.7% |
| STATE STREET CORP | 40,800 | $13.1K | 0 | 0.0% |
| NORTHERN TRUST CORP | 38,081 | $12.2K | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
4 managers exited
Top five by prior-quarter value
- MARSHALL WACE, LLP$36.3K
- WOLVERINE TRADING, LLC$17.2K
- Tamar Securities, LLC$12.7K
- Avion Wealth$1
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for NVNO against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.