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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · CRDF

Cardiff Oncology Inc NASDAQ NMS - GLOBAL MARKET:CRDF

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

17 new27 added67 reduced20 exited

New Positions(17)

ManagerSharesΔ SharesValueΔ Value% Δ
FRANKLIN RESOURCES INC1,205,803+1,205,803$3.4M+$3.4M
Candriam S.C.A.344,437+344,437$967.9K+$967.9K
GROUP ONE TRADING, L.P.41,874+41,874$117.7K+$117.7K
Golden State Equity Partners24,500+24,500$68.8K+$68.8K
Scarborough Advisors, LLC21,004+21,004$51.1K+$51.1K
R Squared Ltd12,701+12,701$35.7K+$35.7K
Tamar Securities, LLC11,495+11,495$32.3K+$32.3K
Capital Advisors Wealth Management, LLC10,500+10,500$29.5K+$29.5K
SageView Advisory Group, LLC6,490+6,490$18.2K+$18.2K
MetLife Investment Management, LLC6,230+6,230$17.5K+$17.5K
GAMMA Investing LLC746+746$2.1K+$2.1K
GSA CAPITAL PARTNERS LLP210,880+210,880$593+$593
Virtu Financial LLC38,479+38,479$108+$108
SG Americas Securities, LLC15,798+15,798$44+$44
Caitong International Asset Management Co., Ltd1+1$3+$3
Motiv8 Investments LLC200+200$1+$1
Avion Wealth225+225$0$0

Added To(27)

ManagerSharesΔ SharesValueΔ Value% Δ
BlackRock, Inc.4,043,614+58,078$11.4M+$3.2M1.4%
VANGUARD GROUP INC3,722,085+133,152$10.5M+$3.1M3.7%
Laurion Capital Management LP2,646,738+180,866$7.4M+$2.4M7.3%
TWO SIGMA INVESTMENTS, LP724,957+520,947$2.0M+$1.6M255.3%
STATE STREET CORP1,191,647+45,288$3.3M+$987.0K4.0%
TWO SIGMA ADVISERS, LP360,500+334,700$1.0M+$959.9K1297.3%
CITADEL ADVISORS LLC425,488+156,623$1.2M+$641.8K58.3%
MILLENNIUM MANAGEMENT LLC194,420+158,519$546.3K+$472.4K441.5%
XTX Topco Ltd219,357+63,196$616.4K+$294.7K40.5%
BARCLAYS PLC107,536+20,297$338.7K+$159.0K23.3%
DEUTSCHE BANK AG\43,888+43,140$123.3K+$121.8K5767.4%
WELLS FARGO & COMPANY/MN83,830+25,311$235.6K+$115.0K43.3%
AlphaCore Capital LLC114,426+4,500$321.5K+$95.1K4.1%
DIMENSIONAL FUND ADVISORS LP55,710+12$156.5K+$41.8K0.0%
FMR LLC37,702+5,502$105.9K+$39.6K17.1%
ALLIANCEBERNSTEIN L.P.48,737+7$137.0K+$36.6K0.0%
MANUFACTURERS LIFE INSURANCE COMPANY, THE19,436+5,696$54.6K+$26.3K41.5%
RAYMOND JAMES FINANCIAL INC26,672+3,040$74.9K+$26.3K12.9%
JPMORGAN CHASE & CO25,977+1,006$73.0K+$21.6K4.0%
BNP PARIBAS ARBITRAGE, SNC12,640+1,058$35.5K+$11.7K9.1%
Brooklyn Investment Group12,649+66$37.3K+$11.4K0.5%
ProShare Advisors LLC11,328+728$31.8K+$10.0K6.9%
Belpointe Asset Management LLC11,778+25$33.1K+$8.9K0.2%
Sterling Capital Management LLC2,455+119$6.9K+$2.1K5.1%
HRT FINANCIAL LP29,408+15,073$82+$53105.1%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO52+4$146+$478.3%
CWM, LLC495+51$1$011.5%

Reduced(67)

ManagerSharesΔ SharesValueΔ Value% Δ
Pfizer Inc2,411,5750$6.8M+$1.8M0.0%
UBS Group AG87,429-751,746$245.7K-$1.5M-89.6%
ACORN CAPITAL ADVISORS, LLC1,962,0840$5.5M+$1.5M0.0%
GEODE CAPITAL MANAGEMENT, LLC1,523,015-20,305$4.3M+$1.1M-1.3%
BLAIR WILLIAM & CO/IL1,948,847-264,759$5.5M+$916.2K-12.0%
Royal Bank of Canada1,725-231,425$4.0K-$729.0K-99.3%
FLPUTNAM INVESTMENT MANAGEMENT CO595,328-1,905$1.7M+$442.6K-0.3%
NORTHERN TRUST CORP461,753-57,999$1.3M+$226.8K-11.2%
Bank of New York Mellon Corp328,995-18,490$924.5K+$208.7K-5.3%
Nuveen, LLC80,220-114,090$225.4K-$174.9K-58.7%
GOLDMAN SACHS GROUP INC385,086-69,640$1.1M+$145.4K-15.3%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC188,655-660$530.1K+$140.1K-0.3%
Avestar Capital, LLC136,145-4,324$382.6K+$93.2K-3.1%
SUSQUEHANNA INTERNATIONAL GROUP, LLP274,040-69,466$770.1K+$62.4K-20.2%
HB Wealth Management, LLC71,491-448$200.9K+$52.7K-0.6%
Assenagon Asset Management S.A.67,2310$188.9K+$50.4K0.0%
RHUMBLINE ADVISERS78,389-8,867$220.3K+$40.5K-10.2%
CAPSTONE INVESTMENT ADVISORS, LLC51,1900$143.8K+$38.4K0.0%
Glenview Trust Co43,1280$121.2K+$32.3K0.0%
Rockefeller Capital Management L.P.56,500-6,000$158.8K+$30.0K-9.6%
JANE STREET GROUP, LLC132,850-61,878$373.3K-$27.8K-31.8%
ELKHORN PARTNERS LIMITED PARTNERSHIP38,100-900$107.1K+$26.7K-2.3%
Police & Firemen's Retirement System of New Jersey7,973-15,784$22.4K-$26.5K-66.4%
HighTower Advisors, LLC34,2060$96.1K+$25.7K0.0%
MORGAN STANLEY235,834-74,825$662.7K+$22.7K-24.1%
Creative Planning37,454-2,648$105.2K+$22.6K-6.6%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.28,753-38$80.8K+$21.5K-0.1%
INTECH INVESTMENT MANAGEMENT LLC27,9910$78.7K+$21.0K0.0%
UNITED BANK22,4110$63.0K+$16.8K0.0%
Post Resch Tallon Group Inc.22,503-35$63.2K+$16.8K-0.1%
Baker Ellis Asset Management LLC20,0000$56.2K+$15.0K0.0%
BANK OF AMERICA CORP /DE/41,264-8,057$116.0K+$14.4K-16.3%
Invst, LLC36,0000$101.2K-$12.2K0.0%
FinDec Wealth Services, Inc.16,0000$45.0K+$12.0K0.0%
Invesco Ltd.22,182-3,100$62.3K+$10.3K-12.3%
Gladstone Institutional Advisory LLC13,0000$36.5K+$9.8K0.0%
INTEGRITY ALLIANCE, LLC.12,8600$36.1K+$9.6K0.0%
Voya Investment Management LLC12,5620$35.3K+$9.4K0.0%
PFG Investments, LLC12,5010$35.1K+$9.4K0.0%
MAI Capital Management51,591-14,701$145.0K+$8.4K-22.2%
Ledgewood Wealth Advisors, LLC11,1900$31.4K+$8.4K0.0%
Proactive Wealth Strategies LLC10,0000$28.1K+$7.5K0.0%
Security National Bank9,7670$27.4K+$7.3K0.0%
Hurley Capital, LLC7,1000$20.0K+$5.3K0.0%
Legal & General Group Plc6,1850$17.4K+$4.6K0.0%
Ameritas Investment Partners, Inc.5,6780$16.0K+$4.3K0.0%
Russell Investments Group, Ltd.5,1350$14.4K+$3.9K0.0%
Tower Research Capital LLC (TRC)5,989-3,754$16.8K-$3.2K-38.5%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM3,816-54$10.7K+$2.8K-1.4%
NEW YORK STATE COMMON RETIREMENT FUND3,6000$10.1K+$2.7K0.0%
US BANCORP \DE\3,1090$8.7K+$2.3K0.0%
SRS Capital Advisors, Inc.304-558$854-$921-64.7%
NBC SECURITIES, INC.1,0000$2.8K+$7500.0%
CITIGROUP INC1,403-219$3.9K+$600-13.5%
Clearstead Advisors, LLC7000$2.0K+$5250.0%
PNC Financial Services Group, Inc.58-178$163-$323-75.4%
Farther Finance Advisors, LLC3220$905+$2420.0%
SBI Securities Co., Ltd.144-1$405+$106-0.7%
IFP Advisors, Inc00$68+$68
NewEdge Advisors, LLC810$228+$610.0%
JONES FINANCIAL COMPANIES LLLP500$141+$380.0%
PRICE T ROWE ASSOCIATES INC /MD/31,3300$89+$240.0%
Cornerstone Planning Group LLC50$8-$30.0%
Front Row Advisors LLC10$3+$10.0%
ROSS\JOHNSON & Associates LLC10$3+$10.0%
AMALGAMATED BANK1,948-61$5+$1-3.0%
Lido Advisors, LLC14,9810$30.9K$00.0%

Sold Out(20)

ManagerSharesΔ SharesValueΔ Value% Δ
NATIONAL BANK OF CANADA /FI/0-208,700$0-$429.9K
RENAISSANCE TECHNOLOGIES LLC0-101,800$0-$209.7K
Focus Partners Wealth0-5,185$0-$205.3K
Cubist Systematic Strategies, LLC0-88,903$0-$183.1K
WOLVERINE TRADING, LLC0-66,000$0-$137.3K
AQR CAPITAL MANAGEMENT LLC0-48,281$0-$99.5K
Quadrature Capital Ltd0-31,493$0-$64.7K
READYSTATE ASSET MANAGEMENT LP0-21,024$0-$43.3K
TWO SIGMA SECURITIES, LLC0-16,528$0-$34.0K
BRIGHTON JONES LLC0-16,506$0-$34.0K
JEPPSON WEALTH MANAGEMENT, LLC0-12,001$0-$24.7K
Quarry LP0-11,135$0-$22.9K
CIBC Private Wealth Group, LLC0-3,000$0-$6.2K
ADVISOR GROUP HOLDINGS, INC.0-2,002$0-$4.2K
Parallel Advisors, LLC0-1,000$0-$2.1K
Vermillion & White Wealth Management Group, LLC0-500$0-$1.0K
Optiver Holding B.V.0-498$0-$1.0K
NISA INVESTMENT ADVISORS, LLC0-209$0-$431
COMMONWEALTH EQUITY SERVICES, LLC0-28,465$0-$59
SIMPLEX TRADING, LLC0-9,053$0-$18

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
BlackRock, Inc.4,043,614$11.4M+58,0781.4%
VANGUARD GROUP INC3,722,085$10.5M+133,1523.7%
Laurion Capital Management LP2,646,738$7.4M+180,8667.3%
Pfizer Inc2,411,575$6.8M00.0%
ACORN CAPITAL ADVISORS, LLC1,962,084$5.5M00.0%
BLAIR WILLIAM & CO/IL1,948,847$5.5M-264,759-12.0%
GEODE CAPITAL MANAGEMENT, LLC1,523,015$4.3M-20,305-1.3%
FRANKLIN RESOURCES INC1,205,803$3.4M+1,205,803
STATE STREET CORP1,191,647$3.3M+45,2884.0%
TWO SIGMA INVESTMENTS, LP724,957$2.0M+520,947255.3%
FLPUTNAM INVESTMENT MANAGEMENT CO595,328$1.7M-1,905-0.3%
NORTHERN TRUST CORP461,753$1.3M-57,999-11.2%
CITADEL ADVISORS LLC425,488$1.2M+156,62358.3%
GOLDMAN SACHS GROUP INC385,086$1.1M-69,640-15.3%
TWO SIGMA ADVISERS, LP360,500$1.0M+334,7001297.3%
Candriam S.C.A.344,437$967.9K+344,437
Bank of New York Mellon Corp328,995$924.5K-18,490-5.3%
SUSQUEHANNA INTERNATIONAL GROUP, LLP274,040$770.1K-69,466-20.2%
MORGAN STANLEY235,834$662.7K-74,825-24.1%
XTX Topco Ltd219,357$616.4K+63,19640.5%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for CRDF against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.