New Positions
16 managers initiated
Top five by reported value
BridgeBio Oncology Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:BBOT
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
16 new12 added26 reduced3 exited
Total Institutional Holders
54
as of 2025-12-31
Top Holder
Cormorant Asset Management, LP
$223.8M
Largest QoQ Increase
ARMISTICE CAPITAL, LLC
+588,000 sh
Largest QoQ Decrease
SILVERARC CAPITAL MANAGEMENT, LLC
-457,414 sh
New Positions(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Catalio Capital Management, LP | 410,700 | +410,700 | $31.4M | +$31.4M | — |
| HighVista Strategies LLC | 229,263 | +229,263 | $2.9M | +$2.9M | — |
| GOLDMAN SACHS GROUP INC | 94,651 | +94,651 | $1.2M | +$1.2M | — |
| RENAISSANCE TECHNOLOGIES LLC | 74,300 | +74,300 | $930.2K | +$930.2K | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 54,192 | +54,192 | $670.4K | +$670.4K | — |
| Qube Research & Technologies Ltd | 35,952 | +35,952 | $450.1K | +$450.1K | — |
| BNP PARIBAS ARBITRAGE, SNC | 26,472 | +26,472 | $331.4K | +$331.4K | — |
| BIT Capital GmbH | 25,000 | +25,000 | $313.0K | +$313.0K | — |
| Point72 Asset Management, L.P. | 23,584 | +23,584 | $295.3K | +$295.3K | — |
| Quadrature Capital Ltd | 12,922 | +12,922 | $161.8K | +$161.8K | — |
| Squarepoint Ops LLC | 11,515 | +11,515 | $144.2K | +$144.2K | — |
| Persistent Asset Partners Ltd | 8,585 | +8,585 | $107.5K | +$107.5K | — |
| CIBC Private Wealth Group, LLC | 5,000 | +5,000 | $62.6K | +$62.6K | — |
| Rockefeller Capital Management L.P. | 700 | +700 | $8.8K | +$8.8K | — |
| WELLS FARGO & COMPANY/MN | 300 | +300 | $3.8K | +$3.8K | — |
| FNY Investment Advisers, LLC | 100 | +100 | $1 | +$1 | — |
Added To(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | 1,000,000 | +588,000 | $12.5M | +$7.7M | 142.7% |
| Paradigm Biocapital Advisors LP | 2,261,749 | +395,608 | $28.3M | +$6.7M | 21.2% |
| Laurion Capital Management LP | 1,464,938 | +419,138 | $18.3M | +$6.2M | 40.1% |
| VANGUARD GROUP INC | 791,095 | +143,496 | $9.9M | +$2.4M | 22.1% |
| BlackRock, Inc. | 2,084,837 | +36,285 | $26.1M | +$2.4M | 1.8% |
| FMR LLC | 240,300 | +78,223 | $3.0M | +$1.1M | 48.3% |
| GEODE CAPITAL MANAGEMENT, LLC | 561,987 | +20,385 | $7.0M | +$764.9K | 3.8% |
| STATE STREET CORP | 218,278 | +41,583 | $2.7M | +$686.7K | 23.5% |
| UBS Group AG | 93,369 | +41,143 | $1.2M | +$564.2K | 78.8% |
| MORGAN STANLEY | 14,352 | +13,491 | $179.7K | +$169.7K | 1566.9% |
| XTX Topco Ltd | 28,633 | +5,249 | $358.5K | +$87.7K | 22.4% |
| BANK OF AMERICA CORP /DE/ | 3,990 | +2,661 | $50.0K | +$34.6K | 200.2% |
Reduced(26)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Cormorant Asset Management, LP | 17,878,594 | 0 | $223.8M | +$16.8M | 0.0% |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 4,885,446 | 0 | $61.2M | +$4.6M | 0.0% |
| Omega Fund Management, LLC | 3,289,661 | 0 | $41.2M | +$3.1M | 0.0% |
| ADAR1 Capital Management, LLC | 226,248 | -274,980 | $2.8M | -$3.0M | -54.9% |
| EcoR1 Capital, LLC | 2,823,126 | 0 | $35.3M | +$2.7M | 0.0% |
| Alphabet Inc. | 2,823,126 | 0 | $35.3M | +$2.7M | 0.0% |
| ENAVATE SCIENCES GP, LLC | 2,626,946 | 0 | $32.9M | +$2.5M | 0.0% |
| CITADEL ADVISORS LLC | 2,530,324 | -7,817 | $31.7M | +$2.3M | -0.3% |
| WELLINGTON MANAGEMENT GROUP LLP | 2,907,003 | -54,260 | $36.4M | +$2.1M | -1.8% |
| Novo Holdings A/S | 1,961,317 | 0 | $24.6M | +$1.8M | 0.0% |
| STEMPOINT CAPITAL LP | 86,517 | -100,097 | $1.1M | -$1.1M | -53.6% |
| MILLENNIUM MANAGEMENT LLC | 241,415 | -128,148 | $3.0M | -$1.0M | -34.7% |
| Octagon Capital Advisors LP | 1,043,110 | 0 | $13.1M | +$980.5K | 0.0% |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,082,362 | 0 | $13.4M | +$974.1K | 0.0% |
| Aisling Capital Management LP | 564,625 | 0 | $7.1M | +$530.7K | 0.0% |
| NORTHERN TRUST CORP | 58,034 | -37,923 | $726.6K | -$384.6K | -39.5% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,400,000 | -87,621 | $17.5M | +$301.3K | -5.9% |
| BOOTHBAY FUND MANAGEMENT, LLC | 67,034 | -29,517 | $839.3K | -$278.8K | -30.6% |
| Casdin Capital, LLC | 282,312 | 0 | $3.5M | +$265.4K | 0.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 279,046 | -304 | $3.5M | +$258.8K | -0.1% |
| Sio Capital Management, LLC | 130,628 | 0 | $1.6M | +$122.8K | 0.0% |
| Woodline Partners LP | 103,707 | 0 | $1.3M | +$97.5K | 0.0% |
| MOORE CAPITAL MANAGEMENT, LP | 100,000 | 0 | $1.3M | +$94.0K | 0.0% |
| Ikarian Capital, LLC | 220,231 | -25,000 | $2.8M | -$82.5K | -10.2% |
| TD Asset Management Inc | 117,150 | -12,912 | $1.5M | -$39.4K | -9.9% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 803,134 | -81,908 | $10.1K | -$193 | -9.3% |
Sold Out(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | -457,414 | $0 | -$5.3M | — |
| China Universal Asset Management Co., Ltd. | 0 | -5,000 | $0 | -$57.9K | — |
| Royal Bank of Canada | 0 | -16 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
New & Closed Positions this quarter
Closed Positions
3 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for BBOT against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.