New Positions
6 managers initiated
Top five by reported value
- Revelation Capital Management, LLC$1.3M
- MARSHALL WACE, LLP$341.3K
- JANE STREET GROUP, LLC$174.5K
- Scientech Research LLC$119.1K
- OMERS ADMINISTRATION Corp$90.5K
Artiva Biotherapeutics Inc NASDAQ NMS - GLOBAL MARKET:ARTV
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
6 new4 added25 reduced14 exited
Total Institutional Holders
35
as of 2025-12-31
Top Holder
RA CAPITAL MANAGEMENT, L.P.
$42.3M
Largest QoQ Increase
Revelation Capital Management, LLC
+299,311 sh
Largest QoQ Decrease
CITADEL ADVISORS LLC
-798,397 sh
New Positions(6)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Revelation Capital Management, LLC | 299,311 | +299,311 | $1.3M | +$1.3M | — |
| MARSHALL WACE, LLP | 79,559 | +79,559 | $341.3K | +$341.3K | — |
| JANE STREET GROUP, LLC | 40,671 | +40,671 | $174.5K | +$174.5K | — |
| Scientech Research LLC | 27,757 | +27,757 | $119.1K | +$119.1K | — |
| OMERS ADMINISTRATION Corp | 21,100 | +21,100 | $90.5K | +$90.5K | — |
| ADVISOR GROUP HOLDINGS, INC. | 32 | +32 | $137 | +$137 | — |
Added To(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 246,006 | +86,888 | $1.1M | +$598.7K | 54.6% |
| TWO SIGMA INVESTMENTS, LP | 144,864 | +124,500 | $621.5K | +$563.0K | 611.4% |
| RENAISSANCE TECHNOLOGIES LLC | 116,200 | +37,053 | $498.5K | +$271.3K | 46.8% |
| UBS Group AG | 36,873 | +15,730 | $158.2K | +$97.5K | 74.4% |
Reduced(25)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9,853,302 | 0 | $42.3M | +$14.0M | 0.0% |
| 5AM Venture Management, LLC | 2,353,304 | 0 | $10.1M | +$3.3M | 0.0% |
| VR Adviser, LLC | 1,609,569 | 0 | $6.9M | +$2.3M | 0.0% |
| FRANKLIN RESOURCES INC | 520,327 | 0 | $2.2M | +$738.9K | 0.0% |
| venBio Partners LLC | 648,507 | -500,468 | $2.8M | -$515.5K | -43.5% |
| BNP PARIBAS ARBITRAGE, SNC | 542 | -118,005 | $2.3K | -$337.9K | -99.5% |
| WELLINGTON MANAGEMENT GROUP LLP | 194,108 | 0 | $832.7K | +$275.6K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 217,097 | -45,063 | $931.3K | +$178.9K | -17.2% |
| Alyeska Investment Group, L.P. | 100,000 | 0 | $429.0K | +$142.0K | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 101,117 | -9,779 | $434.1K | +$115.6K | -8.8% |
| GOLDMAN SACHS GROUP INC | 12,060 | -37,717 | $51.7K | -$91.1K | -75.8% |
| BlackRock, Inc. | 212,538 | -81,884 | $911.8K | +$66.8K | -27.8% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 35,000 | 0 | $150.2K | +$49.7K | 0.0% |
| BANK OF AMERICA CORP /DE/ | 113 | -16,032 | $484 | -$45.9K | -99.3% |
| BARCLAYS PLC | 1,906 | -10,790 | $2.9K | -$33.6K | -85.0% |
| Tower Research Capital LLC (TRC) | 1,103 | -8,878 | $4.7K | -$23.9K | -88.9% |
| STATE STREET CORP | 35,824 | -24,000 | $153.7K | -$18.0K | -40.1% |
| JPMORGAN CHASE & CO | 187 | -3,815 | $802 | -$10.7K | -95.3% |
| Russell Investments Group, Ltd. | 5,491 | 0 | $23.6K | +$7.8K | 0.0% |
| MORGAN STANLEY | 27,072 | -15,757 | $116.1K | -$6.8K | -36.8% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 10,691 | -3,611 | $45.9K | +$4.8K | -25.2% |
| Royal Bank of Canada | 339 | -1,259 | $1.0K | -$2.0K | -78.8% |
| WELLS FARGO & COMPANY/MN | 1,500 | -200 | $6.4K | +$1.6K | -11.8% |
| FMR LLC | 3,558 | -1,362 | $15.3K | +$1.1K | -27.7% |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 400 | 0 | $1.7K | +$568 | 0.0% |
Sold Out(14)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 0 | -798,397 | $0 | -$2.3M | — |
| NORGES BANK | 0 | -30,000 | $0 | -$463.5K | — |
| CITIGROUP INC | 0 | -105,573 | $0 | -$303.0K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -54,881 | $0 | -$164.6K | — |
| XTX Topco Ltd | 0 | -47,973 | $0 | -$137.7K | — |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | -39,133 | $0 | -$112.3K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -8,811 | $0 | -$83.8K | — |
| Qube Research & Technologies Ltd | 0 | -25,552 | $0 | -$73.3K | — |
| China Universal Asset Management Co., Ltd. | 0 | -4,281 | $0 | -$12.3K | — |
| Mirae Asset Global Investments Co., Ltd. | 0 | -944 | $0 | -$2.7K | — |
| GF FUND MANAGEMENT CO. LTD. | 0 | -510 | $0 | -$1.5K | — |
| EverSource Wealth Advisors, LLC | 0 | -159 | $0 | -$456 | — |
| HRT FINANCIAL LP | 0 | -26,953 | $0 | -$77 | — |
| Cloud Capital Management, LLC | 0 | -11 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9,853,302 | $42.3M | 0 | 0.0% |
| 5AM Venture Management, LLC | 2,353,304 | $10.1M | 0 | 0.0% |
| VR Adviser, LLC | 1,609,569 | $6.9M | 0 | 0.0% |
| venBio Partners LLC | 648,507 | $2.8M | -500,468 | -43.5% |
| FRANKLIN RESOURCES INC | 520,327 | $2.2M | 0 | 0.0% |
| Revelation Capital Management, LLC | 299,311 | $1.3M | +299,311 | — |
| VANGUARD GROUP INC | 246,006 | $1.1M | +86,888 | 54.6% |
| MILLENNIUM MANAGEMENT LLC | 217,097 | $931.3K | -45,063 | -17.2% |
| BlackRock, Inc. | 212,538 | $911.8K | -81,884 | -27.8% |
| WELLINGTON MANAGEMENT GROUP LLP | 194,108 | $832.7K | 0 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 144,864 | $621.5K | +124,500 | 611.4% |
| RENAISSANCE TECHNOLOGIES LLC | 116,200 | $498.5K | +37,053 | 46.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 101,117 | $434.1K | -9,779 | -8.8% |
| Alyeska Investment Group, L.P. | 100,000 | $429.0K | 0 | 0.0% |
| MARSHALL WACE, LLP | 79,559 | $341.3K | +79,559 | — |
| JANE STREET GROUP, LLC | 40,671 | $174.5K | +40,671 | — |
| UBS Group AG | 36,873 | $158.2K | +15,730 | 74.4% |
| STATE STREET CORP | 35,824 | $153.7K | -24,000 | -40.1% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 35,000 | $150.2K | 0 | 0.0% |
| Scientech Research LLC | 27,757 | $119.1K | +27,757 | — |
New & Closed Positions this quarter
Closed Positions
14 managers exited
Top five by prior-quarter value
- CITADEL ADVISORS LLC$2.3M
- NORGES BANK$463.5K
- CITIGROUP INC$303.0K
- CHARLES SCHWAB INVESTMENT MANAGEMENT INC$164.6K
- XTX Topco Ltd$137.7K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ARTV against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.