New Positions
34 managers initiated
Top five by reported value
- Saturn V Capital Management LLC$30.6M
- Octagon Capital Advisors LP$24.7M
- BIOIMPACT CAPITAL LLC$23.4M
- Siren, L.L.C.$4.9M
- MARSHALL WACE, LLP$3.6M
Alumis Inc NASDAQ NMS - GLOBAL MARKET:ALMS
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
34 new47 added54 reduced28 exited
Total Institutional Holders
135
as of 2025-12-31
Top Holder
AyurMaya Capital Management Company, LP
$147.8M
Largest QoQ Increase
Saturn V Capital Management LLC
+3,135,953 sh
Largest QoQ Decrease
Trium Capital LLP
-2,229,004 sh
New Positions(34)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Saturn V Capital Management LLC | 3,135,953 | +3,135,953 | $30.6M | +$30.6M | — |
| Octagon Capital Advisors LP | 2,530,700 | +2,530,700 | $24.7M | +$24.7M | — |
| BIOIMPACT CAPITAL LLC | 2,401,992 | +2,401,992 | $23.4M | +$23.4M | — |
| Siren, L.L.C. | 500,000 | +500,000 | $4.9M | +$4.9M | — |
| MARSHALL WACE, LLP | 372,901 | +372,901 | $3.6M | +$3.6M | — |
| D. E. Shaw & Co., Inc. | 231,747 | +231,747 | $2.3M | +$2.3M | — |
| Ikarian Capital, LLC | 211,100 | +211,100 | $2.1M | +$2.1M | — |
| Verition Fund Management LLC | 80,062 | +80,062 | $781.4K | +$781.4K | — |
| BOOTHBAY FUND MANAGEMENT, LLC | 58,000 | +58,000 | $566.1K | +$566.1K | — |
| PSP Research LLC | 43,769 | +43,769 | $427.2K | +$427.2K | — |
| Creative Planning | 38,110 | +38,110 | $372.0K | +$372.0K | — |
| FOX RUN MANAGEMENT, L.L.C. | 37,707 | +37,707 | $368.0K | +$368.0K | — |
| Brevan Howard Capital Management LP | 34,917 | +34,917 | $340.8K | +$340.8K | — |
| Grange Capital, LLC | 32,000 | +32,000 | $312.3K | +$312.3K | — |
| Dynamic Technology Lab Private Ltd | 26,567 | +26,567 | $259.0K | +$259.0K | — |
| Balyasny Asset Management LLC | 24,769 | +24,769 | $241.7K | +$241.7K | — |
| Virtus Investment Advisers, Inc. | 23,153 | +23,153 | $226.0K | +$226.0K | — |
| Schonfeld Strategic Advisors LLC | 23,028 | +23,028 | $224.8K | +$224.8K | — |
| BANK OF NOVA SCOTIA | 20,900 | +20,900 | $204.0K | +$204.0K | — |
| MERCER GLOBAL ADVISORS INC /ADV | 14,908 | +14,908 | $145.5K | +$145.5K | — |
| PDT Partners, LLC | 14,562 | +14,562 | $142.1K | +$142.1K | — |
| Banco BTG Pactual S.A. | 14,302 | +14,302 | $139.6K | +$139.6K | — |
| SIGNATUREFD, LLC | 1,266 | +1,266 | $12.4K | +$12.4K | — |
| GAMMA Investing LLC | 792 | +792 | $7.7K | +$7.7K | — |
| Aster Capital Management (DIFC) Ltd | 728 | +728 | $7.1K | +$7.1K | — |
| Allworth Financial LP | 450 | +450 | $4.4K | +$4.4K | — |
| Optiver Holding B.V. | 306 | +306 | $3.0K | +$3.0K | — |
| IFP Advisors, Inc | 110 | +110 | $756 | +$756 | — |
| Global Retirement Partners, LLC | 65 | +65 | $634 | +$634 | — |
| Virtu Financial LLC | 50,283 | +50,283 | $491 | +$491 | — |
| GSA CAPITAL PARTNERS LLP | 30,913 | +30,913 | $302 | +$302 | — |
| Torren Management, LLC | 14 | +14 | $137 | +$137 | — |
| Larson Financial Group LLC | 10 | +10 | $98 | +$98 | — |
| Sunbelt Securities, Inc. | 7 | +7 | $68 | +$68 | — |
Added To(47)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Samsara BioCapital, LLC | 5,756,984 | +955,614 | $56.2M | +$37.0M | 19.9% |
| BlackRock, Inc. | 4,566,502 | +373,425 | $44.6M | +$27.8M | 8.9% |
| Cormorant Asset Management, LP | 3,635,596 | +1,488,200 | $35.5M | +$26.9M | 69.3% |
| VANGUARD GROUP INC | 4,103,290 | +73,675 | $40.0M | +$24.0M | 1.8% |
| MILLENNIUM MANAGEMENT LLC | 1,151,118 | +834,089 | $11.2M | +$10.0M | 263.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,487,626 | +94,340 | $14.5M | +$9.0M | 6.8% |
| STATE STREET CORP | 1,259,446 | +157,560 | $12.3M | +$7.9M | 14.3% |
| MORGAN STANLEY | 506,529 | +174,123 | $4.9M | +$3.6M | 52.4% |
| Invesco Ltd. | 421,819 | +292,250 | $4.1M | +$3.6M | 225.6% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 504,075 | +13,073 | $4.9M | +$3.0M | 2.7% |
| TWO SIGMA INVESTMENTS, LP | 298,219 | +212,135 | $2.9M | +$2.6M | 246.4% |
| GOLDMAN SACHS GROUP INC | 427,072 | +9,992 | $4.2M | +$2.5M | 2.4% |
| JPMORGAN CHASE & CO | 356,337 | +87,670 | $3.5M | +$2.4M | 32.6% |
| Nuveen, LLC | 169,506 | +68,771 | $1.7M | +$1.3M | 68.3% |
| Mariner, LLC | 145,045 | +60,172 | $1.4M | +$1.1M | 70.9% |
| Susquehanna Portfolio Strategies, LLC | 172,779 | +14,022 | $1.7M | +$1.1M | 8.8% |
| Bank of New York Mellon Corp | 160,138 | +23,426 | $1.6M | +$1.0M | 17.1% |
| WELLINGTON MANAGEMENT GROUP LLP | 169,093 | +3,590 | $1.7M | +$990.0K | 2.2% |
| Quantinno Capital Management LP | 135,446 | +47,838 | $1.3M | +$972.4K | 54.6% |
| WELLS FARGO & COMPANY/MN | 129,448 | +40,182 | $1.3M | +$907.2K | 45.0% |
| BNP PARIBAS ARBITRAGE, SNC | 46,884 | +35,114 | $457.6K | +$410.6K | 298.3% |
| DEUTSCHE BANK AG\ | 41,112 | +16,376 | $401.3K | +$302.6K | 66.2% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 163,084 | +40,383 | $760.0K | +$270.4K | 32.9% |
| TWO SIGMA ADVISERS, LP | 38,074 | +4,600 | $371.6K | +$238.0K | 13.7% |
| Kera Capital Partners, Inc. | 11,003 | +26 | $269.7K | +$225.9K | 0.2% |
| FMR LLC | 23,987 | +17,056 | $234.1K | +$206.5K | 246.1% |
| INTECH INVESTMENT MANAGEMENT LLC | 29,303 | +5,757 | $286.0K | +$192.0K | 24.4% |
| AXQ CAPITAL, LP | 26,417 | +6,965 | $257.8K | +$180.2K | 35.8% |
| Inscription Capital, LLC | 26,667 | +6,233 | $260.3K | +$178.7K | 30.5% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 26,240 | +269 | $256.1K | +$152.5K | 1.0% |
| XTX Topco Ltd | 24,955 | +343 | $243.6K | +$145.4K | 1.4% |
| CITIGROUP INC | 14,070 | +10,405 | $137.3K | +$122.7K | 283.9% |
| Russell Investments Group, Ltd. | 15,029 | +8,610 | $146.7K | +$121.1K | 134.1% |
| IEQ CAPITAL, LLC | 17,421 | +690 | $170.0K | +$103.3K | 4.1% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,661 | +318 | $172.4K | +$103.2K | 1.8% |
| ProShare Advisors LLC | 14,627 | +1,618 | $142.8K | +$90.9K | 12.4% |
| BARCLAYS PLC | 90,060 | +6,692 | $270.2K | -$62.5K | 8.0% |
| Mirae Asset Global Investments Co., Ltd. | 4,724 | +979 | $46.1K | +$31.2K | 26.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,481 | +39 | $34.0K | +$20.2K | 1.1% |
| Parallel Advisors, LLC | 2,059 | +36 | $20.1K | +$12.0K | 1.8% |
| NISA INVESTMENT ADVISORS, LLC | 755 | +502 | $7.4K | +$6.4K | 198.4% |
| Versant Capital Management, Inc | 650 | +508 | $6.3K | +$5.8K | 357.7% |
| US BANCORP \DE\ | 581 | +328 | $5.7K | +$4.7K | 129.6% |
| True Wealth Design, LLC | 244 | +2 | $2.4K | +$1.4K | 0.8% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 50,422 | +22,148 | $493 | +$380 | 78.3% |
| CWM, LLC | 10,431 | +47 | $102 | +$61 | 0.5% |
| AMALGAMATED BANK | 1,776 | +143 | $17 | +$10 | 8.8% |
Reduced(54)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| AyurMaya Capital Management Company, LP | 15,139,706 | 0 | $147.8M | +$87.4M | 0.0% |
| Foresite Capital Management V, LLC | 5,779,348 | 0 | $56.4M | +$33.3M | 0.0% |
| venBio Partners LLC | 4,619,803 | 0 | $45.1M | +$26.7M | 0.0% |
| Foresite Capital Management VI LLC | 4,247,670 | 0 | $41.5M | +$24.5M | 0.0% |
| Nextech Invest, Ltd. | 2,915,998 | 0 | $28.5M | +$16.8M | 0.0% |
| SR ONE CAPITAL MANAGEMENT, LP | 1,959,896 | 0 | $19.1M | +$11.3M | 0.0% |
| BAKER BROS. ADVISORS LP | 1,562,500 | 0 | $15.3M | +$9.0M | 0.0% |
| Yu Fan | 789,618 | 0 | $7.7M | +$4.6M | 0.0% |
| Omega Fund Management, LLC | 653,223 | 0 | $6.4M | +$3.8M | 0.0% |
| Trium Capital LLP | 893,107 | -2,229,004 | $8.7M | -$3.7M | -71.4% |
| ORBIMED ADVISORS LLC | 1,102,730 | -823,693 | $10.8M | +$3.1M | -42.8% |
| TOWERVIEW LLC | 495,000 | 0 | $4.8M | +$2.9M | 0.0% |
| Opaleye Management Inc. | 535,000 | -130,000 | $5.2M | +$2.6M | -19.5% |
| NORTHERN TRUST CORP | 418,248 | -20,724 | $4.1M | +$2.3M | -4.7% |
| UBS Group AG | 113,997 | -648,678 | $1.1M | -$1.9M | -85.0% |
| Exome Asset Management LLC | 292,250 | -520 | $2.9M | +$1.7M | -0.2% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 290,733 | -760,612 | $2.8M | -$1.4M | -72.3% |
| STIFEL FINANCIAL CORP | 209,729 | 0 | $2.0M | +$1.2M | 0.0% |
| JANE STREET GROUP, LLC | 250,433 | -642,576 | $2.4M | -$1.1M | -72.0% |
| AQR CAPITAL MANAGEMENT LLC | 137,792 | -3,125 | $1.3M | +$782.6K | -2.2% |
| LMR Partners LLP | 40,000 | -218,442 | $390.4K | -$640.8K | -84.5% |
| ExodusPoint Capital Management, LP | 11,197 | -155,574 | $109.3K | -$556.1K | -93.3% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 87,832 | 0 | $857.2K | +$506.8K | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 108,200 | -43,368 | $1.1M | +$451.3K | -28.6% |
| ALLIANCEBERNSTEIN L.P. | 76,594 | -4,306 | $747.6K | +$424.8K | -5.3% |
| RHUMBLINE ADVISERS | 69,236 | -4,793 | $675.7K | +$380.4K | -6.5% |
| CITADEL ADVISORS LLC | 186,811 | -356,288 | $1.8M | -$343.7K | -65.6% |
| BANK OF AMERICA CORP /DE/ | 138,341 | -125,576 | $1.4M | +$297.2K | -47.6% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 56,728 | -17,000 | $553.7K | +$259.5K | -23.1% |
| MetLife Investment Management, LLC | 32,479 | -110 | $317.0K | +$187.0K | -0.3% |
| DIMENSIONAL FUND ADVISORS LP | 20,516 | 0 | $200.2K | +$118.4K | 0.0% |
| STRS OHIO | 500 | -23,326 | $4.9K | -$90.2K | -97.9% |
| Police & Firemen's Retirement System of New Jersey | 15,340 | 0 | $149.7K | +$88.5K | 0.0% |
| China Universal Asset Management Co., Ltd. | 15,840 | -1,142 | $154.6K | +$86.8K | -6.7% |
| GROUP ONE TRADING, L.P. | 1,405 | -21,178 | $13.7K | -$76.4K | -93.8% |
| NEW YORK STATE COMMON RETIREMENT FUND | 11,767 | 0 | $114.8K | +$67.9K | 0.0% |
| Birchview Capital, LP | 10,000 | 0 | $97.6K | +$57.7K | 0.0% |
| AMERICAN CENTURY COMPANIES INC | 10,322 | -992 | $100.7K | +$55.6K | -8.8% |
| SRS Capital Advisors, Inc. | 1,036 | -12,624 | $10.1K | -$44.4K | -92.4% |
| Ameritas Investment Partners, Inc. | 4,827 | 0 | $47.1K | +$27.9K | 0.0% |
| Legal & General Group Plc | 4,954 | -362 | $48.4K | +$27.1K | -6.8% |
| Sterling Capital Management LLC | 3,253 | -604 | $31.7K | +$16.4K | -15.7% |
| GF FUND MANAGEMENT CO. LTD. | 1,910 | -174 | $18.6K | +$10.3K | -8.3% |
| COMERICA BANK | 932 | 0 | $9.1K | +$5.4K | 0.0% |
| ROTHSCHILD INVESTMENT LLC | 415 | -30 | $4.0K | +$2.3K | -6.7% |
| Royal Bank of Canada | 2,202 | -3,299 | $21.0K | +$2.0K | -60.0% |
| Tower Research Capital LLC (TRC) | 1,298 | -2,306 | $12.7K | -$1.7K | -64.0% |
| SBI Securities Co., Ltd. | 3 | -420 | $29 | -$1.7K | -99.3% |
| PNC Financial Services Group, Inc. | 388 | -262 | $3.8K | +$1.2K | -40.3% |
| BFSG, LLC | 192 | 0 | $1.9K | +$1.1K | 0.0% |
| Transamerica Financial Advisors, Inc. | 97 | -31 | $947 | +$436 | -24.2% |
| CoreCap Advisors, LLC | 26 | 0 | $254 | +$150 | 0.0% |
| EverSource Wealth Advisors, LLC | 447 | -657 | $4.4K | -$42 | -59.5% |
| Daiwa Securities Group Inc. | 347 | 0 | $3 | +$2 | 0.0% |
Sold Out(28)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| AyurMaya Capital Management Company, LP | 15,139,706 | $147.8M | 0 | 0.0% |
| Foresite Capital Management V, LLC | 5,779,348 | $56.4M | 0 | 0.0% |
| Samsara BioCapital, LLC | 5,756,984 | $56.2M | +955,614 | 19.9% |
| venBio Partners LLC | 4,619,803 | $45.1M | 0 | 0.0% |
| BlackRock, Inc. | 4,566,502 | $44.6M | +373,425 | 8.9% |
| Foresite Capital Management VI LLC | 4,247,670 | $41.5M | 0 | 0.0% |
| VANGUARD GROUP INC | 4,103,290 | $40.0M | +73,675 | 1.8% |
| Cormorant Asset Management, LP | 3,635,596 | $35.5M | +1,488,200 | 69.3% |
| Saturn V Capital Management LLC | 3,135,953 | $30.6M | +3,135,953 | — |
| Nextech Invest, Ltd. | 2,915,998 | $28.5M | 0 | 0.0% |
| Octagon Capital Advisors LP | 2,530,700 | $24.7M | +2,530,700 | — |
| BIOIMPACT CAPITAL LLC | 2,401,992 | $23.4M | +2,401,992 | — |
| SR ONE CAPITAL MANAGEMENT, LP | 1,959,896 | $19.1M | 0 | 0.0% |
| BAKER BROS. ADVISORS LP | 1,562,500 | $15.3M | 0 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,487,626 | $14.5M | +94,340 | 6.8% |
| STATE STREET CORP | 1,259,446 | $12.3M | +157,560 | 14.3% |
| MILLENNIUM MANAGEMENT LLC | 1,151,118 | $11.2M | +834,089 | 263.1% |
| ORBIMED ADVISORS LLC | 1,102,730 | $10.8M | -823,693 | -42.8% |
| Trium Capital LLP | 893,107 | $8.7M | -2,229,004 | -71.4% |
| Yu Fan | 789,618 | $7.7M | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
28 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ALMS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.