New Positions
12 managers initiated
Top five by reported value
- Prospera Financial Services Inc$105.5K
- XTX Topco Ltd$104.6K
- Quadrature Capital Ltd$103.5K
- Point72 Asset Management, L.P.$76.7K
- OMERS ADMINISTRATION Corp$47.4K
Acumen Pharmaceuticals, Inc. NMS:ABOS
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
12 new12 added47 reduced12 exited
Total Institutional Holders
71
as of 2025-12-31
Top Holder
RA CAPITAL MANAGEMENT, L.P.
$31.5M
Largest QoQ Increase
SUSQUEHANNA INTERNATIONAL GROUP, LLP
+158,758 sh
Largest QoQ Decrease
RENAISSANCE TECHNOLOGIES LLC
-161,192 sh
New Positions(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Prospera Financial Services Inc | 50,000 | +50,000 | $105.5K | +$105.5K | — |
| XTX Topco Ltd | 49,563 | +49,563 | $104.6K | +$104.6K | — |
| Quadrature Capital Ltd | 49,046 | +49,046 | $103.5K | +$103.5K | — |
| Point72 Asset Management, L.P. | 36,365 | +36,365 | $76.7K | +$76.7K | — |
| OMERS ADMINISTRATION Corp | 22,454 | +22,454 | $47.4K | +$47.4K | — |
| MARSHALL WACE, LLP | 20,907 | +20,907 | $44.1K | +$44.1K | — |
| Independent Advisor Alliance | 19,000 | +19,000 | $40.1K | +$40.1K | — |
| NINE MASTS CAPITAL Ltd | 10,637 | +10,637 | $22.4K | +$22.4K | — |
| Tower Research Capital LLC (TRC) | 4,457 | +4,457 | $9.4K | +$9.4K | — |
| FLAGSHIP HARBOR ADVISORS, LLC | 350 | +350 | $739 | +$739 | — |
| Clearstead Advisors, LLC | 60 | +60 | $127 | +$127 | — |
| Virtu Financial LLC | 10,922 | +10,922 | $23 | +$23 | — |
Added To(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 1,653,772 | +2,300 | $3.5M | +$665.4K | 0.1% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 373,198 | +158,758 | $787.4K | +$420.8K | 74.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 410,206 | +11,428 | $865.7K | +$183.6K | 2.9% |
| BANK OF AMERICA CORP /DE/ | 240,152 | +26,423 | $506.7K | +$141.2K | 12.4% |
| MORGAN STANLEY | 166,905 | +17,504 | $352.2K | +$96.7K | 11.7% |
| NORTHERN TRUST CORP | 75,212 | +10,258 | $158.7K | +$47.6K | 15.8% |
| Qube Research & Technologies Ltd | 47,985 | +15,104 | $101.2K | +$45.0K | 45.9% |
| DIMENSIONAL FUND ADVISORS LP | 49,062 | +5,538 | $103.5K | +$29.1K | 12.7% |
| PFG Investments, LLC | 19,000 | +7,500 | $40.1K | +$20.4K | 65.2% |
| WELLS FARGO & COMPANY/MN | 7,100 | +600 | $15.0K | +$3.9K | 9.2% |
| Larson Financial Group LLC | 4,348 | +348 | $9.2K | +$2.3K | 8.7% |
| ACADIAN ASSET MANAGEMENT LLC | 152,780 | +74,860 | $320 | +$189 | 96.1% |
Reduced(47)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 14,932,063 | 0 | $31.5M | +$6.0M | 0.0% |
| Sands Capital Ventures, LLC | 3,417,075 | 0 | $7.2M | +$1.4M | 0.0% |
| FRANKLIN RESOURCES INC | 2,305,096 | 0 | $4.9M | +$922.0K | 0.0% |
| FMR LLC | 2,027,497 | -1,828 | $4.3M | +$807.9K | -0.1% |
| Knollwood Investment Advisory, LLC | 1,628,510 | 0 | $3.4M | +$651.4K | 0.0% |
| Alyeska Investment Group, L.P. | 939,603 | 0 | $2.0M | +$375.8K | 0.0% |
| ADAR1 Capital Management, LLC | 891,183 | 0 | $1.9M | +$356.5K | 0.0% |
| Laurion Capital Management LP | 867,046 | 0 | $1.8M | +$346.8K | 0.0% |
| Pathstone Holdings, LLC | 859,110 | 0 | $1.8M | +$343.6K | 0.0% |
| Hudson Bay Capital Management LP | 725,000 | -4 | $1.5M | +$290.0K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 584,143 | -17,573 | $1.2M | +$203.6K | -2.9% |
| TWO SIGMA ADVISERS, LP | 421,800 | -1,800 | $890.0K | +$165.6K | -0.4% |
| RENAISSANCE TECHNOLOGIES LLC | 423,100 | -161,192 | $892.7K | -$106.4K | -27.6% |
| Ikarian Capital, LLC | 254,312 | -11,457 | $536.6K | +$82.1K | -4.3% |
| CITADEL ADVISORS LLC | 372,083 | -133,625 | $785.1K | -$79.7K | -26.4% |
| BlackRock, Inc. | 169,505 | -5,185 | $357.7K | +$58.9K | -3.0% |
| JANE STREET GROUP, LLC | 142,123 | -65,116 | $299.9K | -$54.5K | -31.4% |
| TWO SIGMA INVESTMENTS, LP | 143,221 | -56,225 | $302.2K | -$38.9K | -28.2% |
| CATALYST FINANCIAL PARTNERS LLC | 89,699 | 0 | $189.3K | +$35.9K | 0.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 170,171 | -20,000 | $359.1K | +$33.9K | -10.5% |
| STATE STREET CORP | 100,178 | -6,500 | $211.4K | +$29.0K | -6.1% |
| BARCLAYS PLC | 29,991 | 0 | $34.8K | -$16.5K | 0.0% |
| Intrepid Financial Planning Group LLC | 30,150 | 0 | $63.6K | +$12.1K | 0.0% |
| Catalyst Funds Management Pty Ltd | 29,600 | 0 | $62.5K | +$11.8K | 0.0% |
| UBS Group AG | 21,562 | -9,279 | $45.5K | -$7.2K | -30.1% |
| PINNACLE ASSOCIATES LTD | 18,020 | 0 | $38.0K | +$7.2K | 0.0% |
| Pinnacle Wealth Management Advisory Group, LLC | 18,020 | 0 | $38.0K | +$7.2K | 0.0% |
| CLUNE & ASSOCIATES, LTD. | 16,500 | 0 | $34.8K | +$6.6K | 0.0% |
| Royal Bank of Canada | 2,282 | -7,227 | $5.0K | -$5.0K | -76.0% |
| ADVISOR GROUP HOLDINGS, INC. | 6,851 | -400 | $14.5K | +$4.1K | -5.5% |
| BOOTHBAY FUND MANAGEMENT, LLC | 39,585 | -11,457 | $83.5K | -$3.8K | -22.4% |
| GROUP ONE TRADING, L.P. | 4,752 | -3,046 | $10.0K | -$3.3K | -39.1% |
| GOLDMAN SACHS GROUP INC | 117,851 | -29,297 | $248.7K | -$3.0K | -19.9% |
| PNC Financial Services Group, Inc. | 3,080 | 0 | $6.5K | +$1.2K | 0.0% |
| Rockefeller Capital Management L.P. | 3,000 | 0 | $6.3K | +$1.2K | 0.0% |
| JPMORGAN CHASE & CO | 2,409 | -623 | $4.2K | -$1.1K | -20.5% |
| TFC Financial Management, Inc. | 2,500 | 0 | $5.3K | +$1.0K | 0.0% |
| NISA INVESTMENT ADVISORS, LLC | 1,229 | 0 | $2.6K | +$491 | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 1,224 | 0 | $2.6K | +$490 | 0.0% |
| SBI Securities Co., Ltd. | 323 | -195 | $682 | -$204 | -37.6% |
| EverSource Wealth Advisors, LLC | 407 | 0 | $859 | +$163 | 0.0% |
| SG Americas Securities, LLC | 401,047 | -2,831 | $846 | +$155 | -0.7% |
| Farther Finance Advisors, LLC | 200 | 0 | $422 | +$80 | 0.0% |
| NBT BANK N A /NY | 2 | 0 | $422 | +$80 | 0.0% |
| SRS Capital Advisors, Inc. | 26 | 0 | $55 | +$11 | 0.0% |
| Optiver Holding B.V. | 5 | -1 | $11 | +$1 | -16.7% |
| CWM, LLC | 147 | -597 | $0 | -$1 | -80.2% |
Sold Out(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -71,800 | $0 | -$154.5K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -116,902 | $0 | -$128.6K | — |
| Cubist Systematic Strategies, LLC | 0 | -23,904 | $0 | -$40.9K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -16,044 | $0 | -$27.4K | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | -16,001 | $0 | -$27.4K | — |
| Savant Capital, LLC | 0 | -11,045 | $0 | -$18.9K | — |
| Integrated Wealth Concepts LLC | 0 | -10,179 | $0 | -$17.4K | — |
| Advisory Services Network, LLC | 0 | -1,111 | $0 | -$1.9K | — |
| Bell Investment Advisors, Inc | 0 | -362 | $0 | -$620 | — |
| CITIGROUP INC | 0 | -151 | $0 | -$258 | — |
| GSA CAPITAL PARTNERS LLP | 0 | -32,103 | $0 | -$55 | — |
| HRT FINANCIAL LP | 0 | -14,014 | $0 | -$23 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 14,932,063 | $31.5M | 0 | 0.0% |
| Sands Capital Ventures, LLC | 3,417,075 | $7.2M | 0 | 0.0% |
| FRANKLIN RESOURCES INC | 2,305,096 | $4.9M | 0 | 0.0% |
| FMR LLC | 2,027,497 | $4.3M | -1,828 | -0.1% |
| VANGUARD GROUP INC | 1,653,772 | $3.5M | +2,300 | 0.1% |
| Knollwood Investment Advisory, LLC | 1,628,510 | $3.4M | 0 | 0.0% |
| Alyeska Investment Group, L.P. | 939,603 | $2.0M | 0 | 0.0% |
| ADAR1 Capital Management, LLC | 891,183 | $1.9M | 0 | 0.0% |
| Laurion Capital Management LP | 867,046 | $1.8M | 0 | 0.0% |
| Pathstone Holdings, LLC | 859,110 | $1.8M | 0 | 0.0% |
| Hudson Bay Capital Management LP | 725,000 | $1.5M | -4 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 584,143 | $1.2M | -17,573 | -2.9% |
| RENAISSANCE TECHNOLOGIES LLC | 423,100 | $892.7K | -161,192 | -27.6% |
| TWO SIGMA ADVISERS, LP | 421,800 | $890.0K | -1,800 | -0.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 410,206 | $865.7K | +11,428 | 2.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 373,198 | $787.4K | +158,758 | 74.0% |
| CITADEL ADVISORS LLC | 372,083 | $785.1K | -133,625 | -26.4% |
| Ikarian Capital, LLC | 254,312 | $536.6K | -11,457 | -4.3% |
| BANK OF AMERICA CORP /DE/ | 240,152 | $506.7K | +26,423 | 12.4% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 170,171 | $359.1K | -20,000 | -10.5% |
New & Closed Positions this quarter
Closed Positions
12 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for ABOS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.