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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · TXMD

TherapeuticsMD Inc NASDAQ NMS - GLOBAL MARKET:TXMD

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

6 new8 added31 reduced6 exited

New Positions(6)

ManagerSharesΔ SharesValueΔ Value% Δ
SUSQUEHANNA INTERNATIONAL GROUP, LLP59,264+59,264$96.6K+$96.6K
JANE STREET GROUP, LLC12,200+12,200$19.9K+$19.9K
GROUP ONE TRADING, L.P.1,596+1,596$2.6K+$2.6K
Smartleaf Asset Management LLC601+601$986+$986
IFP Advisors, Inc42+42$57+$57
CIBC Private Wealth Group, LLC20+20$33+$33

Added To(8)

ManagerSharesΔ SharesValueΔ Value% Δ
VANGUARD GROUP INC397,056+20,228$647.2K+$247.8K5.4%
Tejara Capital Ltd350,852+6,649$571.9K+$201.9K1.9%
RENAISSANCE TECHNOLOGIES LLC96,500+61,000$157.3K+$119.1K171.8%
CITADEL ADVISORS LLC48,840+14,567$79.6K+$43.3K42.5%
ADVISOR GROUP HOLDINGS, INC.9,297+8,400$15.2K+$14.2K936.5%
FMR LLC8,290+1$13.5K+$4.7K0.0%
UBS Group AG1,114+752$1.8K+$1.4K207.7%
BANK OF AMERICA CORP /DE/108+2$176+$621.9%

Reduced(31)

ManagerSharesΔ SharesValueΔ Value% Δ
Rubric Capital Management LP1,192,1910$1.9M+$661.7K0.0%
Clearline Capital LP635,2220$1.0M+$352.5K0.0%
ADAR1 Capital Management, LLC209,2100$341.0K+$116.1K0.0%
MORGAN STANLEY129,217-1,355$210.6K+$70.3K-1.0%
BlackRock, Inc.116,1320$189.3K+$64.5K0.0%
GEODE CAPITAL MANAGEMENT, LLC106,100-2,983$173.0K+$57.3K-2.7%
STATE STREET CORP30,1000$49.1K+$17.2K0.0%
NORTHERN TRUST CORP16,448-9$26.8K+$9.1K-0.1%
BRIDGEWAY CAPITAL MANAGEMENT, LLC17,000-17,000$27.7K-$8.3K-50.0%
Tower Research Capital LLC (TRC)2,471-262$4.0K+$1.1K-9.6%
NATIONAL BANK OF CANADA /FI/610-60$976+$266-8.9%
JPMORGAN CHASE & CO2930$477+$1670.0%
SBI Securities Co., Ltd.2550$416+$1420.0%
US BANCORP \DE\2460$401+$1370.0%
BNP PARIBAS ARBITRAGE, SNC2260$368+$1250.0%
HUNTINGTON NATIONAL BANK1200$196+$670.0%
Activest Wealth Management400$65+$220.0%
WELLS FARGO & COMPANY/MN370$60+$200.0%
Steward Partners Investment Advisory, LLC350$57+$190.0%
Farther Finance Advisors, LLC300$49+$170.0%
Provenance Wealth Advisors, LLC200$33+$110.0%
Truvestments Capital LLC100$16+$50.0%
HARBOUR INVESTMENTS, INC.80$13+$40.0%
ASSETMARK, INC40$7+$30.0%
CITIGROUP INC10$2+$10.0%
Strategic Advocates LLC10$2+$10.0%
EverSource Wealth Advisors, LLC10$2+$10.0%
Smallwood Wealth Investment Management, LLC20$3+$10.0%
Royal Bank of Canada154-174$0$0-53.0%
Banque Cantonale Vaudoise70$0$00.0%
CWM, LLC200$0$00.0%

Sold Out(6)

ManagerSharesΔ SharesValueΔ Value% Δ
J. Goldman & Co LP0-13,562$0-$14.6K
TWO SIGMA SECURITIES, LLC0-11,967$0-$12.9K
BARCLAYS PLC0-44$0-$47
Wealth Watch Advisors, INC0-22$0-$24
Advisory Services Network, LLC0-14$0-$15
NewEdge Advisors, LLC0-1$0-$1

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
Rubric Capital Management LP1,192,191$1.9M00.0%
Clearline Capital LP635,222$1.0M00.0%
VANGUARD GROUP INC397,056$647.2K+20,2285.4%
Tejara Capital Ltd350,852$571.9K+6,6491.9%
ADAR1 Capital Management, LLC209,210$341.0K00.0%
MORGAN STANLEY129,217$210.6K-1,355-1.0%
BlackRock, Inc.116,132$189.3K00.0%
GEODE CAPITAL MANAGEMENT, LLC106,100$173.0K-2,983-2.7%
RENAISSANCE TECHNOLOGIES LLC96,500$157.3K+61,000171.8%
SUSQUEHANNA INTERNATIONAL GROUP, LLP59,264$96.6K+59,264
CITADEL ADVISORS LLC48,840$79.6K+14,56742.5%
STATE STREET CORP30,100$49.1K00.0%
BRIDGEWAY CAPITAL MANAGEMENT, LLC17,000$27.7K-17,000-50.0%
NORTHERN TRUST CORP16,448$26.8K-9-0.1%
JANE STREET GROUP, LLC12,200$19.9K+12,200
ADVISOR GROUP HOLDINGS, INC.9,297$15.2K+8,400936.5%
FMR LLC8,290$13.5K+10.0%
Tower Research Capital LLC (TRC)2,471$4.0K-262-9.6%
GROUP ONE TRADING, L.P.1,596$2.6K+1,596
UBS Group AG1,114$1.8K+752207.7%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for TXMD against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.