New Positions
20 managers initiated
Top five by reported value
Tenax Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:TENX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
20 new12 added16 reduced5 exited
Total Institutional Holders
48
as of 2025-12-31
Top Holder
Ikarian Capital, LLC
$11.8M
Largest QoQ Increase
PERCEPTIVE ADVISORS LLC
+439,142 sh
Largest QoQ Decrease
VR Adviser, LLC
-437,708 sh
New Positions(20)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 439,142 | +439,142 | $5.4M | +$5.4M | — |
| Point72 Asset Management, L.P. | 423,415 | +423,415 | $5.2M | +$5.2M | — |
| DIADEMA PARTNERS LP | 243,170 | +243,170 | $3.0M | +$3.0M | — |
| SPHERA FUNDS MANAGEMENT LTD. | 190,111 | +190,111 | $2.3M | +$2.3M | — |
| FMR LLC | 141,100 | +141,100 | $1.7M | +$1.7M | — |
| Persistent Asset Partners Ltd | 65,272 | +65,272 | $795.7K | +$795.7K | — |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 44,900 | +44,900 | $547.3K | +$547.3K | — |
| Artia Global Partners LP | 42,080 | +42,080 | $513.0K | +$513.0K | — |
| TWO SIGMA INVESTMENTS, LP | 33,470 | +33,470 | $408.0K | +$408.0K | — |
| GOLDMAN SACHS GROUP INC | 22,409 | +22,409 | $273.2K | +$273.2K | — |
| Quadrature Capital Ltd | 20,648 | +20,648 | $251.7K | +$251.7K | — |
| BNP PARIBAS ARBITRAGE, SNC | 15,296 | +15,296 | $186.5K | +$186.5K | — |
| TWO SIGMA ADVISERS, LP | 13,178 | +13,178 | $160.6K | +$160.6K | — |
| CI Private Wealth, LLC | 12,388 | +12,388 | $151.0K | +$151.0K | — |
| Stonepine Capital Management, LLC | 11,884 | +11,884 | $144.9K | +$144.9K | — |
| LETKO, BROSSEAU & ASSOCIATES INC | 10,650 | +10,650 | $129.8K | +$129.8K | — |
| JPMORGAN CHASE & CO | 902 | +902 | $11.0K | +$11.0K | — |
| BARCLAYS PLC | 11 | +11 | $63 | +$63 | — |
| Allworth Financial LP | 1 | +1 | $13 | +$13 | — |
| CITIGROUP INC | 1 | +1 | $12 | +$12 | — |
Added To(12)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MORGAN STANLEY | 596,376 | +418,047 | $7.3M | +$5.9M | 234.4% |
| Siren, L.L.C. | 427,141 | +74,700 | $5.2M | +$2.5M | 21.2% |
| MARSHALL WACE, LLP | 298,153 | +120,944 | $3.6M | +$2.3M | 68.2% |
| VANGUARD GROUP INC | 255,664 | +93,864 | $3.1M | +$1.9M | 58.0% |
| CITADEL ADVISORS LLC | 129,528 | +86,275 | $1.6M | +$1.2M | 199.5% |
| RENAISSANCE TECHNOLOGIES LLC | 125,579 | +68,979 | $1.5M | +$1.1M | 121.9% |
| Woodline Partners LP | 143,481 | +55,270 | $1.7M | +$1.1M | 62.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 55,699 | +21,274 | $679.0K | +$417.0K | 61.8% |
| ADAR1 Capital Management, LLC | 63,673 | +10,245 | $776.2K | +$369.6K | 19.2% |
| BlackRock, Inc. | 16,714 | +16,413 | $203.7K | +$201.5K | 5452.8% |
| BANK OF AMERICA CORP /DE/ | 3,780 | +3,526 | $46.1K | +$44.1K | 1388.2% |
| UBS Group AG | 676 | +557 | $8.2K | +$7.3K | 468.1% |
Reduced(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Ikarian Capital, LLC | 967,600 | 0 | $11.8M | +$4.4M | 0.0% |
| RTW INVESTMENTS, LP | 378,346 | 0 | $4.6M | +$1.7M | 0.0% |
| BOOTHBAY FUND MANAGEMENT, LLC | 352,206 | 0 | $4.3M | +$1.6M | 0.0% |
| BVF INC/IL | 339,549 | 0 | $4.1M | +$1.6M | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 302,473 | -11,239 | $3.7M | +$1.3M | -3.6% |
| Vivo Capital, LLC | 208,333 | 0 | $2.5M | +$954.2K | 0.0% |
| Integral Health Asset Management, LLC | 167,000 | 0 | $2.0M | +$764.9K | 0.0% |
| JANUS HENDERSON GROUP PLC | 166,666 | 0 | $2.0M | +$745.8K | 0.0% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 83,333 | 0 | $1.0M | +$381.7K | 0.0% |
| Velan Capital Investment Management LP | 83,333 | 0 | $1.0M | +$381.7K | 0.0% |
| Vestal Point Capital, LP | 53,439 | 0 | $651.4K | +$244.8K | 0.0% |
| Tower Research Capital LLC (TRC) | 199 | -302 | $2.4K | -$1.4K | -60.3% |
| JONES FINANCIAL COMPANIES LLLP | 1 | 0 | $12 | +$5 | 0.0% |
| UMA Financial Services, Inc. | 1 | 0 | $13 | +$5 | 0.0% |
| Rockefeller Capital Management L.P. | 1 | -1 | $12 | -$3 | -50.0% |
| Union Bancaire Privee, UBP SA | 1 | 0 | $9 | +$3 | 0.0% |
Sold Out(5)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VR Adviser, LLC | 0 | -437,708 | $0 | -$3.3M | — |
| DRW Securities, LLC | 0 | -10,514 | $0 | -$80.0K | — |
| Virtu Financial LLC | 0 | -12,119 | $0 | -$92 | — |
| SBI Securities Co., Ltd. | 0 | -2 | $0 | -$15 | — |
| Wealthspire Advisors, LLC | 0 | -1 | $0 | -$8 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Ikarian Capital, LLC | 967,600 | $11.8M | 0 | 0.0% |
| MORGAN STANLEY | 596,376 | $7.3M | +418,047 | 234.4% |
| PERCEPTIVE ADVISORS LLC | 439,142 | $5.4M | +439,142 | — |
| Siren, L.L.C. | 427,141 | $5.2M | +74,700 | 21.2% |
| Point72 Asset Management, L.P. | 423,415 | $5.2M | +423,415 | — |
| RTW INVESTMENTS, LP | 378,346 | $4.6M | 0 | 0.0% |
| BOOTHBAY FUND MANAGEMENT, LLC | 352,206 | $4.3M | 0 | 0.0% |
| BVF INC/IL | 339,549 | $4.1M | 0 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 302,473 | $3.7M | -11,239 | -3.6% |
| MARSHALL WACE, LLP | 298,153 | $3.6M | +120,944 | 68.2% |
| VANGUARD GROUP INC | 255,664 | $3.1M | +93,864 | 58.0% |
| DIADEMA PARTNERS LP | 243,170 | $3.0M | +243,170 | — |
| Vivo Capital, LLC | 208,333 | $2.5M | 0 | 0.0% |
| SPHERA FUNDS MANAGEMENT LTD. | 190,111 | $2.3M | +190,111 | — |
| Integral Health Asset Management, LLC | 167,000 | $2.0M | 0 | 0.0% |
| JANUS HENDERSON GROUP PLC | 166,666 | $2.0M | 0 | 0.0% |
| Woodline Partners LP | 143,481 | $1.7M | +55,270 | 62.6% |
| FMR LLC | 141,100 | $1.7M | +141,100 | — |
| CITADEL ADVISORS LLC | 129,528 | $1.6M | +86,275 | 199.5% |
| RENAISSANCE TECHNOLOGIES LLC | 125,579 | $1.5M | +68,979 | 121.9% |
New & Closed Positions this quarter
Closed Positions
5 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for TENX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.