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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Silence Therapeutics plc (SLNCF)

PNK · Biotechnology

$2.50+1.00 (+66.67%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$354.3M
P/E (TTM)
EPS
$-0.54
Div Yield
52W Range
$1.06–$2.63
Beta
1.38

Company overview

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.

Peers in Healthcare

Silence Therapeutics plc has no peer companies in this window.

Recent press releases

Silence Therapeutics plc has not issued a press release in this window.

SEC filings

All filings →

Silence Therapeutics plc has not filed an SEC document in this window.

Silence Therapeutics plc has no reported insider trades in the last 90 days.

Institutional holders

All holders →
As of 2025-12-31 · prior 2025-09-30
808,032 sh● NEW
324,630 sh-73.1%
1,542,427 sh+48.0%
3,033,560 sh0.0%
2,911,438 sh0.0%
659,592 sh+121.0%
365,369 sh● NEW

People at Silence Therapeutics plc

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No officers or directors have been indexed for Silence Therapeutics plc.

Quarterly financials

Full financials →
Revenue trend
03/25
$142.0K
NI -$28.5M
06/25
$224.0K
NI -$27.4M
09/25
$159.0K
NI -$21.0M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-0.15
Prior: $-0.19
Revenue sparkline