New Positions
7 managers initiated
Top five by reported value
SCYNEXIS Inc NASDAQ NMS - GLOBAL MARKET:SCYX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
7 new9 added23 reduced10 exited
Total Institutional Holders
39
as of 2025-12-31
Top Holder
Avidity Partners Management LP
$1.3M
Largest QoQ Increase
GOLDMAN SACHS GROUP INC
+1,984,561 sh
Largest QoQ Decrease
KINGDON CAPITAL MANAGEMENT, L.L.C.
-2,237,048 sh
New Positions(7)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GOLDMAN SACHS GROUP INC | 1,984,561 | +1,984,561 | $1.3M | +$1.3M | — |
| CITADEL ADVISORS LLC | 103,933 | +103,933 | $65.7K | +$65.7K | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 51,015 | +51,015 | $32.3K | +$32.3K | — |
| FLAGSHIP HARBOR ADVISORS, LLC | 12,250 | +12,250 | $24.5K | +$24.5K | — |
| JANE STREET GROUP, LLC | 14,892 | +14,892 | $9.4K | +$9.4K | — |
| MAI Capital Management | 500 | +500 | $317 | +$317 | — |
| SageView Advisory Group, LLC | 39 | +39 | $25 | +$25 | — |
Added To(9)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GEODE CAPITAL MANAGEMENT, LLC | 449,223 | +29,775 | $284.1K | -$38.9K | 7.1% |
| RENAISSANCE TECHNOLOGIES LLC | 176,000 | +1,400 | $111.3K | -$23.1K | 0.8% |
| MORGAN STANLEY | 46,095 | +30,395 | $29.1K | +$17.1K | 193.6% |
| NORTHERN TRUST CORP | 75,454 | +30,506 | $47.7K | +$13.1K | 67.9% |
| RAYMOND JAMES FINANCIAL INC | 33,395 | +11,811 | $21.1K | +$4.5K | 54.7% |
| BANK OF AMERICA CORP /DE/ | 1,891 | +14 | $1.2K | -$250 | 0.7% |
| Creative Planning | 12,633 | +2,362 | $8.0K | +$80 | 23.0% |
| ACADIAN ASSET MANAGEMENT LLC | 583,114 | +166,512 | $367 | +$47 | 40.0% |
| GSA CAPITAL PARTNERS LLP | 160,983 | +56,560 | $102 | +$22 | 54.2% |
Reduced(23)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Avidity Partners Management LP | 2,081,660 | -1,268,868 | $1.3M | -$1.3M | -37.9% |
| VANGUARD GROUP INC | 1,762,322 | 0 | $1.1M | -$243.2K | 0.0% |
| BlackRock, Inc. | 334,648 | 0 | $211.6K | -$46.0K | 0.0% |
| Yakira Capital Management, Inc. | 189,802 | 0 | $120.0K | -$26.1K | 0.0% |
| UBS Group AG | 23,533 | -28,626 | $14.9K | -$25.3K | -54.9% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 163,937 | 0 | $103.7K | -$22.6K | 0.0% |
| WEALTH EFFECTS LLC | 91,500 | -8,000 | $57.9K | -$18.8K | -8.0% |
| Empowered Funds, LLC | 123,697 | 0 | $78.2K | -$17.0K | 0.0% |
| STATE STREET CORP | 120,730 | 0 | $76.3K | -$16.6K | 0.0% |
| LPL Financial LLC | 47,980 | -5,700 | $30.3K | -$11.0K | -10.6% |
| Nierenberg Investment Management Company, Inc. | 75,555 | 0 | $47.8K | -$10.4K | 0.0% |
| Bank of New York Mellon Corp | 35,059 | 0 | $22.2K | -$4.8K | 0.0% |
| CITIGROUP INC | 1,379 | -4,903 | $872 | -$4.0K | -78.0% |
| PDS Planning, Inc | 15,000 | 0 | $9.5K | -$2.1K | 0.0% |
| Pingora Partners LLC | 12,000 | 0 | $7.6K | -$1.7K | 0.0% |
| Royal Bank of Canada | 692 | -308 | $0 | -$1.0K | -30.8% |
| Tower Research Capital LLC (TRC) | 1,806 | -824 | $1.1K | -$883 | -31.3% |
| US BANCORP \DE\ | 3,100 | 0 | $2.0K | -$427 | 0.0% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 2,487 | 0 | $1.6K | -$342 | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 1,730 | 0 | $1.1K | -$335 | 0.0% |
| HighMark Wealth Management LLC | 1,066 | 0 | $674 | -$147 | 0.0% |
| SBI Securities Co., Ltd. | 232 | -6 | $147 | -$36 | -2.5% |
| CWM, LLC | 191 | 0 | $0 | $0 | 0.0% |
Sold Out(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 0 | -2,237,048 | $0 | -$1.7M | — |
| FEDERATED HERMES, INC. | 0 | -1,583,348 | $0 | -$1.2M | — |
| AMH Equity Ltd | 0 | -245,939 | $0 | -$189.4K | — |
| Sequoia Financial Advisors, LLC | 0 | -52,850 | $0 | -$40.7K | — |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | -14,201 | $0 | -$11.3K | — |
| Chicago Partners Investment Group LLC | 0 | -10,330 | $0 | -$7.4K | — |
| WELLS FARGO & COMPANY/MN | 0 | -6,770 | $0 | -$5.2K | — |
| Wealthspire Advisors, LLC | 0 | -3,000 | $0 | -$2.3K | — |
| FMR LLC | 0 | -1,500 | $0 | -$1.2K | — |
| SIMPLEX TRADING, LLC | 0 | -104 | $0 | $0 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Avidity Partners Management LP | 2,081,660 | $1.3M | -1,268,868 | -37.9% |
| GOLDMAN SACHS GROUP INC | 1,984,561 | $1.3M | +1,984,561 | — |
| VANGUARD GROUP INC | 1,762,322 | $1.1M | 0 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 449,223 | $284.1K | +29,775 | 7.1% |
| BlackRock, Inc. | 334,648 | $211.6K | 0 | 0.0% |
| Yakira Capital Management, Inc. | 189,802 | $120.0K | 0 | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 176,000 | $111.3K | +1,400 | 0.8% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 163,937 | $103.7K | 0 | 0.0% |
| Empowered Funds, LLC | 123,697 | $78.2K | 0 | 0.0% |
| STATE STREET CORP | 120,730 | $76.3K | 0 | 0.0% |
| CITADEL ADVISORS LLC | 103,933 | $65.7K | +103,933 | — |
| WEALTH EFFECTS LLC | 91,500 | $57.9K | -8,000 | -8.0% |
| Nierenberg Investment Management Company, Inc. | 75,555 | $47.8K | 0 | 0.0% |
| NORTHERN TRUST CORP | 75,454 | $47.7K | +30,506 | 67.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 51,015 | $32.3K | +51,015 | — |
| LPL Financial LLC | 47,980 | $30.3K | -5,700 | -10.6% |
| MORGAN STANLEY | 46,095 | $29.1K | +30,395 | 193.6% |
| FLAGSHIP HARBOR ADVISORS, LLC | 12,250 | $24.5K | +12,250 | — |
| Bank of New York Mellon Corp | 35,059 | $22.2K | 0 | 0.0% |
| RAYMOND JAMES FINANCIAL INC | 33,395 | $21.1K | +11,811 | 54.7% |
New & Closed Positions this quarter
Closed Positions
10 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for SCYX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.