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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · RNTX

Rein Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:RNTX

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

12 new14 added21 reduced6 exited

New Positions(12)

ManagerSharesΔ SharesValueΔ Value% Δ
ABS Direct Equity Fund LLC125,000+125,000$145.0K+$145.0K
Rock Creek Group, LP100,000+100,000$116.0K+$116.0K
JANE STREET GROUP, LLC61,960+61,960$71.9K+$71.9K
TWO SIGMA INVESTMENTS, LP41,709+41,709$48.4K+$48.4K
Cane Capital Partners, LLC18,000+18,000$20.9K+$20.9K
TWO SIGMA SECURITIES, LLC17,254+17,254$20.0K+$20.0K
HighTower Advisors, LLC10,000+10,000$11.6K+$11.6K
New Millennium Group LLC2,038+2,038$2.4K+$2.4K
HRT FINANCIAL LP33,237+33,237$38+$38
Annandale Capital, LLC15,026+15,026$17+$17
Virtu Financial LLC13,663+13,663$16+$16
Motiv8 Investments LLC25+25$0$0

Added To(14)

ManagerSharesΔ SharesValueΔ Value% Δ
Voss Capital, LLC4,243,969+1,577,437$4.9M+$1.9M59.1%
TEXAS CAPITAL BANK WEALTH MANAGEMENT SERVICES INC262,125+235,954$304.1K+$274.1K901.6%
CITADEL ADVISORS LLC120,083+91,882$139.3K+$107.0K325.8%
STATE STREET CORP75,904+59,900$88.0K+$69.7K374.3%
GEODE CAPITAL MANAGEMENT, LLC284,555+37,244$330.2K+$46.9K15.1%
SUSQUEHANNA INTERNATIONAL GROUP, LLP58,995+28,135$68.4K+$33.1K91.2%
NORTHERN TRUST CORP40,469+14,706$46.9K+$17.4K57.1%
GAGNON SECURITIES LLC240,220+11,528$278.7K+$16.8K5.0%
Global Retirement Partners, LLC19,316+12,116$22.4K+$14.2K168.3%
UBS Group AG9,516+9,433$11.0K+$10.9K11365.1%
MERCER GLOBAL ADVISORS INC /ADV17,961+7,500$20.8K+$8.9K71.7%
RENAISSANCE TECHNOLOGIES LLC22,700+4,402$26.3K+$5.4K24.1%
BlackRock, Inc.55,006+2,132$63.8K+$3.3K4.0%
ADVISOR GROUP HOLDINGS, INC.70+35$81+$41100.0%

Reduced(21)

ManagerSharesΔ SharesValueΔ Value% Δ
Prosight Management, LP442,600-125,298$513.4K-$136.8K-22.1%
BIOS Capital Management, LP1,690,7510$2.0M+$16.9K0.0%
VANGUARD GROUP INC1,165,807-2,600$1.4M+$14.5K-0.2%
Sigma Planning Corp247,277-6,550$298.6K+$8.0K-2.6%
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO511,6100$593.5K+$7.7K0.0%
Cable Car Capital, LP420,0000$487.2K+$6.3K0.0%
Tower Research Capital LLC (TRC)1,957-3,072$2.3K-$3.5K-61.1%
Senvest Management, LLC230,8950$267.8K+$3.5K0.0%
Chicago Partners Investment Group LLC31,0480$42.5K+$1.6K0.0%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO42,4400$49.2K+$6360.0%
Meridian Wealth Advisors, LLC28,4860$33.0K+$4280.0%
Gleason Group, Inc.22,3890$26.0K+$3360.0%
KG&L Capital Management,LLC18,0000$20.9K+$2700.0%
Americana Partners, LLC17,3020$20.1K+$2590.0%
Cetera Investment Advisers12,3640$14.3K+$1850.0%
Rockefeller Capital Management L.P.5,0970$5.9K+$770.0%
BANK OF AMERICA CORP /DE/42-58$49-$66-58.0%
JFS WEALTH ADVISORS, LLC1,5900$1.8K+$240.0%
US BANCORP \DE\1,2500$1.4K+$190.0%
ACADIAN ASSET MANAGEMENT LLC170$0$00.0%
Ronald Blue Trust, Inc.200$23$00.0%

Sold Out(6)

ManagerSharesΔ SharesValueΔ Value% Δ
Royal Bank of Canada0-57,257$0-$101.0K
KCK LTD.0-22,341$0-$52.1K
EXENCIAL WEALTH ADVISORS, LLC0-30,528$0-$35.0K
BLAIR WILLIAM & CO/IL0-23,393$0-$26.8K
XTX Topco Ltd0-14,984$0-$17.2K
Warberg Asset Management LLC0-11,000$0-$12.6K

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
Voss Capital, LLC4,243,969$4.9M+1,577,43759.1%
BIOS Capital Management, LP1,690,751$2.0M00.0%
VANGUARD GROUP INC1,165,807$1.4M-2,600-0.2%
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO511,610$593.5K00.0%
Prosight Management, LP442,600$513.4K-125,298-22.1%
Cable Car Capital, LP420,000$487.2K00.0%
GEODE CAPITAL MANAGEMENT, LLC284,555$330.2K+37,24415.1%
TEXAS CAPITAL BANK WEALTH MANAGEMENT SERVICES INC262,125$304.1K+235,954901.6%
Sigma Planning Corp247,277$298.6K-6,550-2.6%
GAGNON SECURITIES LLC240,220$278.7K+11,5285.0%
Senvest Management, LLC230,895$267.8K00.0%
ABS Direct Equity Fund LLC125,000$145.0K+125,000
CITADEL ADVISORS LLC120,083$139.3K+91,882325.8%
Rock Creek Group, LP100,000$116.0K+100,000
STATE STREET CORP75,904$88.0K+59,900374.3%
JANE STREET GROUP, LLC61,960$71.9K+61,960
SUSQUEHANNA INTERNATIONAL GROUP, LLP58,995$68.4K+28,13591.2%
BlackRock, Inc.55,006$63.8K+2,1324.0%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO42,440$49.2K00.0%
TWO SIGMA INVESTMENTS, LP41,709$48.4K+41,709

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for RNTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.