New Positions
15 managers initiated
Top five by reported value
Galapagos NV PNK:GLPGF
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
15 new29 added47 reduced19 exited
Total Institutional Holders
91
as of 2025-12-31
Top Holder
GILEAD SCIENCES, INC.
$550.6M
Largest QoQ Increase
UBS Group AG
+196,445 sh
Largest QoQ Decrease
TANG CAPITAL MANAGEMENT LLC
-229,975 sh
New Positions(15)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| KOTLER KEVIN | 90,000 | +90,000 | $2.9M | +$2.9M | — |
| Massar Capital Management, LP | 39,000 | +39,000 | $1.3M | +$1.3M | — |
| Western Standard LLC | 32,000 | +32,000 | $1.0M | +$1.0M | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 6,968 | +6,968 | $227.9K | +$227.9K | — |
| Smartleaf Asset Management LLC | 389 | +389 | $12.7K | +$12.7K | — |
| DV EQUITIES, LLC | 332 | +332 | $10.9K | +$10.9K | — |
| Caitong International Asset Management Co., Ltd | 292 | +292 | $9.5K | +$9.5K | — |
| Allworth Financial LP | 139 | +139 | $4.5K | +$4.5K | — |
| SageView Advisory Group, LLC | 80 | +80 | $2.6K | +$2.6K | — |
| Manning & Napier Advisors LLC | 26 | +26 | $848 | +$848 | — |
| Signature Equity Partners, LLC | 22 | +22 | $719 | +$719 | — |
| IMA Wealth, Inc. | 15 | +15 | $490 | +$490 | — |
| ACADIAN ASSET MANAGEMENT LLC | 7,541 | +7,541 | $246 | +$246 | — |
| HUNTINGTON NATIONAL BANK | 4 | +4 | $131 | +$131 | — |
| BESSEMER GROUP INC | 41 | +41 | $1 | +$1 | — |
Added To(29)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| UBS Group AG | 349,444 | +196,445 | $11.4M | +$6.1M | 128.4% |
| MILLENNIUM MANAGEMENT LLC | 339,354 | +186,452 | $11.1M | +$5.8M | 121.9% |
| Madison Avenue Partners, LP | 2,213,169 | +17,394 | $72.4M | -$3.7M | 0.8% |
| CITADEL ADVISORS LLC | 108,196 | +70,927 | $3.5M | +$2.2M | 190.3% |
| D. E. Shaw & Co., Inc. | 274,999 | +73,830 | $9.0M | +$2.0M | 36.7% |
| BlackRock, Inc. | 314,269 | +74,426 | $10.3M | +$2.0M | 31.0% |
| AMERIPRISE FINANCIAL INC | 1,451,239 | +34,305 | $47.5M | -$1.6M | 2.4% |
| ALPS ADVISORS INC | 53,791 | +21,886 | $1.8M | +$653.8K | 68.6% |
| Point72 Asset Management, L.P. | 486,209 | +42,340 | $15.9M | +$523.4K | 9.5% |
| XTX Topco Ltd | 23,219 | +11,162 | $759.3K | +$341.6K | 92.6% |
| Man Group plc | 47,581 | +11,384 | $1.6M | +$302.0K | 31.4% |
| COMMONWEALTH EQUITY SERVICES, LLC | 8,861 | +13 | $289.8K | +$289.4K | 0.1% |
| BARCLAYS PLC | 40,169 | +1,167 | $1.1M | -$226.7K | 3.0% |
| RHUMBLINE ADVISERS | 6,972 | +3,372 | $228.0K | +$103.3K | 93.7% |
| BAROMETER CAPITAL MANAGEMENT INC. | 37,100 | +9,483 | $883.7K | -$72.9K | 34.3% |
| TWO SIGMA ADVISERS, LP | 11,300 | +2,600 | $369.5K | +$68.1K | 29.9% |
| Crossmark Global Holdings, Inc. | 32,977 | +80 | $1.1M | -$61.2K | 0.2% |
| BANK OF AMERICA CORP /DE/ | 30,969 | +20 | $1.0M | -$59.4K | 0.1% |
| SRS Capital Advisors, Inc. | 2,335 | +1,778 | $76.4K | +$57.1K | 319.2% |
| MORGAN STANLEY | 68,285 | +4,222 | $2.2M | +$13.8K | 6.6% |
| FMR LLC | 56,969 | +2,958 | $1.9M | -$8.1K | 5.5% |
| State of Wyoming | 1,227 | +271 | $40.1K | +$7.0K | 28.3% |
| QRG CAPITAL MANAGEMENT, INC. | 16,170 | +1,077 | $528.8K | +$5.9K | 7.1% |
| JPMORGAN CHASE & CO | 239 | +168 | $7.8K | +$5.4K | 236.6% |
| Farther Finance Advisors, LLC | 145 | +144 | $4.7K | +$4.7K | 14400.0% |
| Larson Financial Group LLC | 288 | +132 | $9.4K | +$4.0K | 84.6% |
| Mirae Asset Global Investments Co., Ltd. | 702 | +148 | $23.0K | +$3.8K | 26.7% |
| US BANCORP \DE\ | 182 | +88 | $6.0K | +$2.7K | 93.6% |
| VAN ECK ASSOCIATES CORP | 1,968 | +750 | $64 | +$22 | 61.6% |
Reduced(47)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GILEAD SCIENCES, INC. | 16,707,477 | 0 | $550.6M | -$28.1M | 0.0% |
| TANG CAPITAL MANAGEMENT LLC | 3,921,219 | -229,975 | $128.2M | -$15.6M | -5.5% |
| Prosight Management, LP | 1,074,112 | -75,888 | $35.1M | -$4.7M | -6.6% |
| EcoR1 Capital, LLC | 1,667,119 | 0 | $54.5M | -$3.2M | 0.0% |
| Hudson Bay Capital Management LP | 170,000 | -75,000 | $5.6M | -$2.9M | -30.6% |
| CITIGROUP INC | 404 | -73,449 | $13.2K | -$2.5M | -99.5% |
| SEGALL BRYANT & HAMILL, LLC | 448,096 | -39,100 | $14.7M | -$2.2M | -8.0% |
| RENAISSANCE TECHNOLOGIES LLC | 310,600 | -45,600 | $10.2M | -$2.2M | -12.8% |
| Royal Bank of Canada | 5,355 | -76,389 | $175.0K | -$2.1M | -93.4% |
| GOLDMAN SACHS GROUP INC | 11,144 | -54,997 | $364.4K | -$1.9M | -83.2% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 43,856 | -43,716 | $1.4M | -$1.6M | -49.9% |
| MARSHALL WACE, LLP | 11,200 | -27,260 | $366.2K | -$966.0K | -70.9% |
| DME Capital Management, LP | 482,746 | 0 | $15.8M | -$936.5K | 0.0% |
| Jump Financial, LLC | 29,000 | -22,300 | $948.3K | -$828.7K | -43.5% |
| NORGES BANK | 90,000 | -30,000 | $2.9M | -$511.8K | -25.0% |
| Quadrature Capital Ltd | 15,006 | -11,239 | $490.7K | -$418.4K | -42.8% |
| DAFNA Capital Management LLC | 130,175 | 0 | $4.3M | -$252.5K | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 16,360 | -6,099 | $535.0K | -$243.0K | -27.1% |
| Aquatic Capital Management LLC | 13,712 | -3,804 | $448.4K | -$158.4K | -21.7% |
| Monaco Asset Management SAM | 32,520 | -1,016 | $1.1M | -$98.3K | -3.0% |
| AMERICAN CENTURY COMPANIES INC | 26,729 | -874 | $874.0K | -$82.1K | -3.2% |
| BNP PARIBAS ARBITRAGE, SNC | 11,098 | -756 | $362.9K | -$47.7K | -6.4% |
| MOODY NATIONAL BANK TRUST DIVISION | 20,849 | 0 | $681.8K | -$40.4K | 0.0% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 19,305 | -22 | $631.3K | -$38.2K | -0.1% |
| QUADRANT CAPITAL GROUP LLC | 3,520 | -360 | $115.1K | -$19.3K | -9.3% |
| Erste Asset Management GmbH | 14,000 | 0 | $463.7K | -$18.3K | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 7,851 | 0 | $256.7K | -$15.2K | 0.0% |
| Ascent Group, LLC | 6,237 | -76 | $203.9K | -$14.7K | -1.2% |
| GAMMA Investing LLC | 1,250 | -223 | $40.9K | -$10.2K | -15.1% |
| SIGNATUREFD, LLC | 1,641 | -199 | $53.7K | -$10.1K | -10.8% |
| China Universal Asset Management Co., Ltd. | 2,356 | -155 | $77.0K | -$9.9K | -6.2% |
| EverSource Wealth Advisors, LLC | 32 | -277 | $1.0K | -$9.7K | -89.6% |
| ADVISOR GROUP HOLDINGS, INC. | 370 | -255 | $12.1K | -$9.4K | -40.8% |
| Tower Research Capital LLC (TRC) | 548 | -49 | $17.9K | -$2.8K | -8.2% |
| SIMPLEX TRADING, LLC | 74 | -180 | $2.4K | +$2.4K | -70.9% |
| Parallel Advisors, LLC | 103 | -50 | $3.4K | -$1.9K | -32.7% |
| BRYN MAWR TRUST Co | 36 | -38 | $1.2K | -$1.4K | -51.4% |
| GF FUND MANAGEMENT CO. LTD. | 282 | -23 | $9.2K | -$1.3K | -7.5% |
| ASSETMARK, INC | 22 | -20 | $719 | -$736 | -47.6% |
| CACTI ASSET MANAGEMENT LLC | 1,000 | 0 | $33.1K | -$660 | 0.0% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 281 | 0 | $9.2K | -$545 | 0.0% |
| PNC Financial Services Group, Inc. | 22 | -4 | $719 | -$182 | -15.4% |
| MAI Capital Management | 52 | 0 | $1.7K | -$101 | 0.0% |
| Crewe Advisors LLC | 46 | 0 | $1.5K | -$89 | 0.0% |
| TD PRIVATE CLIENT WEALTH LLC | 24 | 0 | $785 | -$46 | 0.0% |
| NewEdge Advisors, LLC | 6 | 0 | $196 | -$12 | 0.0% |
| Daiwa Securities Group Inc. | 51 | 0 | $2 | $0 | 0.0% |
Sold Out(19)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Cubist Systematic Strategies, LLC | 0 | -104,539 | $0 | -$3.6M | — |
| PRIMECAP MANAGEMENT CO/CA/ | 0 | -50,500 | $0 | -$1.7M | — |
| MATAURO, LLC | 0 | -47,536 | $0 | -$1.6M | — |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 0 | -37,111 | $0 | -$1.3M | — |
| Verition Fund Management LLC | 0 | -20,270 | $0 | -$702.2K | — |
| Caption Management, LLC | 0 | -19,900 | $0 | -$689.3K | — |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0 | -17,469 | $0 | -$605.1K | — |
| NATIONAL BANK OF CANADA /FI/ | 0 | -14,281 | $0 | -$493.5K | — |
| JANE STREET GROUP, LLC | 0 | -9,049 | $0 | -$313.5K | — |
| Brinker Capital Investments, LLC | 0 | -7,261 | $0 | -$251.5K | — |
| Vanguard Personalized Indexing Management, LLC | 0 | -6,106 | $0 | -$211.5K | — |
| Squarepoint Ops LLC | 0 | -6,099 | $0 | -$211.3K | — |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -4,044 | $0 | -$143.5K | — |
| PRINCIPAL SECURITIES, INC. | 0 | -184 | $0 | -$6.4K | — |
| Rockefeller Capital Management L.P. | 0 | -35 | $0 | -$1.2K | — |
| UMA Financial Services, Inc. | 0 | -24 | $0 | -$832 | — |
| Ronald Blue Trust, Inc. | 0 | -10 | $0 | -$346 | — |
| HRT FINANCIAL LP | 0 | -8,697 | $0 | -$301 | — |
| MONTAG A & ASSOCIATES INC | 0 | -6 | $0 | -$208 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| GILEAD SCIENCES, INC. | 16,707,477 | $550.6M | 0 | 0.0% |
| TANG CAPITAL MANAGEMENT LLC | 3,921,219 | $128.2M | -229,975 | -5.5% |
| Madison Avenue Partners, LP | 2,213,169 | $72.4M | +17,394 | 0.8% |
| EcoR1 Capital, LLC | 1,667,119 | $54.5M | 0 | 0.0% |
| AMERIPRISE FINANCIAL INC | 1,451,239 | $47.5M | +34,305 | 2.4% |
| Prosight Management, LP | 1,074,112 | $35.1M | -75,888 | -6.6% |
| Point72 Asset Management, L.P. | 486,209 | $15.9M | +42,340 | 9.5% |
| DME Capital Management, LP | 482,746 | $15.8M | 0 | 0.0% |
| SEGALL BRYANT & HAMILL, LLC | 448,096 | $14.7M | -39,100 | -8.0% |
| UBS Group AG | 349,444 | $11.4M | +196,445 | 128.4% |
| MILLENNIUM MANAGEMENT LLC | 339,354 | $11.1M | +186,452 | 121.9% |
| BlackRock, Inc. | 314,269 | $10.3M | +74,426 | 31.0% |
| RENAISSANCE TECHNOLOGIES LLC | 310,600 | $10.2M | -45,600 | -12.8% |
| D. E. Shaw & Co., Inc. | 274,999 | $9.0M | +73,830 | 36.7% |
| Hudson Bay Capital Management LP | 170,000 | $5.6M | -75,000 | -30.6% |
| DAFNA Capital Management LLC | 130,175 | $4.3M | 0 | 0.0% |
| CITADEL ADVISORS LLC | 108,196 | $3.5M | +70,927 | 190.3% |
| NORGES BANK | 90,000 | $2.9M | -30,000 | -25.0% |
| KOTLER KEVIN | 90,000 | $2.9M | +90,000 | — |
| MORGAN STANLEY | 68,285 | $2.2M | +4,222 | 6.6% |
New & Closed Positions this quarter
Closed Positions
19 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for GLPGF against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.