New Positions
9 managers initiated
Top five by reported value
Context Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:CNTX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
9 new8 added25 reduced4 exited
Total Institutional Holders
42
as of 2025-12-31
Top Holder
BIOIMPACT CAPITAL LLC
$15.7M
Largest QoQ Increase
MILLENNIUM MANAGEMENT LLC
+2,601,216 sh
Largest QoQ Decrease
BIOIMPACT CAPITAL LLC
-4,026,491 sh
New Positions(9)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 2,601,216 | +2,601,216 | $3.8M | +$3.8M | — |
| Point72 Asset Management, L.P. | 52,701 | +52,701 | $77.5K | +$77.5K | — |
| Quadrature Capital Ltd | 46,220 | +46,220 | $67.9K | +$67.9K | — |
| CI Private Wealth, LLC | 15,084 | +15,084 | $22.2K | +$22.2K | — |
| Tower Research Capital LLC (TRC) | 9,611 | +9,611 | $14.1K | +$14.1K | — |
| Strive Financial Group ,LLC | 1,700 | +1,700 | $2.5K | +$2.5K | — |
| Farther Finance Advisors, LLC | 1,500 | +1,500 | $2.2K | +$2.2K | — |
| CITIGROUP INC | 1,348 | +1,348 | $2.0K | +$2.0K | — |
| Virtu Financial LLC | 28,921 | +28,921 | $43 | +$43 | — |
Added To(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MARSHALL WACE, LLP | 2,593,198 | +2,557,448 | $3.8M | +$3.8M | 7153.7% |
| Blue Owl Capital Holdings LP | 7,432,906 | +25,000 | $10.9M | +$3.7M | 0.3% |
| VANGUARD GROUP INC | 3,785,909 | +290,878 | $5.6M | +$2.2M | 8.3% |
| RENAISSANCE TECHNOLOGIES LLC | 508,329 | +188,202 | $747.2K | +$437.1K | 58.8% |
| XTX Topco Ltd | 101,605 | +91,008 | $149.4K | +$139.1K | 858.8% |
| STATE STREET CORP | 165,607 | +13,000 | $243.4K | +$95.6K | 8.5% |
| NORTHERN TRUST CORP | 84,281 | +17,897 | $123.9K | +$59.6K | 26.9% |
| BANK OF AMERICA CORP /DE/ | 933 | +499 | $1.4K | +$951 | 115.0% |
Reduced(25)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Nextech Invest, Ltd. | 7,419,355 | 0 | $10.9M | +$3.7M | 0.0% |
| Deep Track Capital, LP | 7,419,355 | 0 | $10.9M | +$3.7M | 0.0% |
| GREAT POINT PARTNERS LLC | 4,683,711 | 0 | $6.9M | +$2.3M | 0.0% |
| FRANKLIN RESOURCES INC | 4,003,380 | 0 | $5.9M | +$2.0M | 0.0% |
| Nantahala Capital Management, LLC | 37,837 | -1,624,113 | $55.6K | -$1.6M | -97.7% |
| BIOIMPACT CAPITAL LLC | 10,679,391 | -4,026,491 | $15.7M | +$1.5M | -27.4% |
| Blackstone Inc. | 2,440,330 | 0 | $3.6M | +$1.2M | 0.0% |
| Alyeska Investment Group, L.P. | 1,663,355 | 0 | $2.4M | +$833.7K | 0.0% |
| Sio Capital Management, LLC | 1,341,636 | 0 | $2.0M | +$672.4K | 0.0% |
| Avidity Partners Management LP | 5,504,855 | -3,477,000 | $8.1M | -$609.5K | -38.7% |
| BlackRock, Inc. | 848,046 | -924 | $1.2M | +$424.1K | -0.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 608,462 | -115 | $894.9K | +$305.0K | -0.0% |
| ADAR1 Capital Management, LLC | 351,094 | 0 | $516.1K | +$176.0K | 0.0% |
| Walleye Capital LLC | 132,786 | 0 | $195.2K | +$66.6K | 0.0% |
| HighTower Advisors, LLC | 125,852 | 0 | $185.0K | +$63.1K | 0.0% |
| Pathstone Holdings, LLC | 110,244 | 0 | $162.1K | +$55.3K | 0.0% |
| Mill Creek Capital Advisors, LLC | 104,631 | 0 | $153.8K | +$52.4K | 0.0% |
| Velan Capital Investment Management LP | 100,000 | 0 | $147.0K | +$50.1K | 0.0% |
| CITADEL ADVISORS LLC | 34,380 | -68,983 | $50.5K | -$49.6K | -66.7% |
| Clear Harbor Asset Management, LLC | 92,804 | 0 | $136.4K | +$46.5K | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 25,500 | 0 | $37.5K | +$12.9K | 0.0% |
| Cerity Partners LLC | 20,000 | 0 | $29.4K | +$10.0K | 0.0% |
| CAXTON CORP | 18,403 | 0 | $27.1K | +$9.2K | 0.0% |
| UBS Group AG | 490 | -6,892 | $720 | -$6.4K | -93.4% |
| SBI Securities Co., Ltd. | 114 | -3 | $168 | +$55 | -2.6% |
Sold Out(4)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Affinity Asset Advisors, LLC | 0 | -402,653 | $0 | -$390.1K | — |
| Qube Research & Technologies Ltd | 0 | -82,111 | $0 | -$79.5K | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | -21,967 | $0 | -$21.3K | — |
| BARCLAYS PLC | 0 | -167 | $0 | -$162 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| BIOIMPACT CAPITAL LLC | 10,679,391 | $15.7M | -4,026,491 | -27.4% |
| Blue Owl Capital Holdings LP | 7,432,906 | $10.9M | +25,000 | 0.3% |
| Deep Track Capital, LP | 7,419,355 | $10.9M | 0 | 0.0% |
| Nextech Invest, Ltd. | 7,419,355 | $10.9M | 0 | 0.0% |
| Avidity Partners Management LP | 5,504,855 | $8.1M | -3,477,000 | -38.7% |
| GREAT POINT PARTNERS LLC | 4,683,711 | $6.9M | 0 | 0.0% |
| FRANKLIN RESOURCES INC | 4,003,380 | $5.9M | 0 | 0.0% |
| VANGUARD GROUP INC | 3,785,909 | $5.6M | +290,878 | 8.3% |
| MILLENNIUM MANAGEMENT LLC | 2,601,216 | $3.8M | +2,601,216 | — |
| MARSHALL WACE, LLP | 2,593,198 | $3.8M | +2,557,448 | 7153.7% |
| Blackstone Inc. | 2,440,330 | $3.6M | 0 | 0.0% |
| Alyeska Investment Group, L.P. | 1,663,355 | $2.4M | 0 | 0.0% |
| Sio Capital Management, LLC | 1,341,636 | $2.0M | 0 | 0.0% |
| BlackRock, Inc. | 848,046 | $1.2M | -924 | -0.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 608,462 | $894.9K | -115 | -0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 508,329 | $747.2K | +188,202 | 58.8% |
| ADAR1 Capital Management, LLC | 351,094 | $516.1K | 0 | 0.0% |
| STATE STREET CORP | 165,607 | $243.4K | +13,000 | 8.5% |
| Walleye Capital LLC | 132,786 | $195.2K | 0 | 0.0% |
| HighTower Advisors, LLC | 125,852 | $185.0K | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
4 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for CNTX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.