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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · CGEN

Compugen Ltd NASDAQ NMS - GLOBAL MARKET:CGEN

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

14 new11 added45 reduced11 exited

New Positions(14)

ManagerSharesΔ SharesValueΔ Value% Δ
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.1,020,000+1,020,000$1.6M+$1.6M
Stonepine Capital Management, LLC305,400+305,400$467.3K+$467.3K
XTX Topco Ltd67,903+67,903$103.9K+$103.9K
WINTON GROUP Ltd55,066+55,066$84.3K+$84.3K
SECURITY NATIONAL BANK OF SIOUX CITY IOWA /IA/25,000+25,000$38.3K+$38.3K
BIP Wealth, LLC15,000+15,000$22.9K+$22.9K
Altshuler Shaham Ltd13,600+13,600$20.8K+$20.8K
Quadrature Capital Ltd12,796+12,796$19.6K+$19.6K
GLENMEDE TRUST CO NA12,000+12,000$18.4K+$18.4K
RM Financial Services, LLC11,580+11,580$17.7K+$17.7K
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC10,313+10,313$16.0K+$16.0K
Keating Financial Advisory Services, Inc.7,670+7,670$11.7K+$11.7K
Allworth Financial LP270+270$414+$414
BANK HAPOALIM BM24,000+24,000$37+$37

Added To(11)

ManagerSharesΔ SharesValueΔ Value% Δ
SILVERARC CAPITAL MANAGEMENT, LLC3,479,805+168,640$5.3M+$456.7K5.1%
TWO SIGMA INVESTMENTS, LP303,943+106,068$465.0K+$174.2K53.6%
RENAISSANCE TECHNOLOGIES LLC1,456,900+51,565$2.2M+$163.2K3.7%
UBS Group AG350,461+53,862$536.2K+$100.2K18.1%
MARSHALL WACE, LLP106,304+61,202$162.6K+$96.3K135.7%
Platform Technology Partners50,000+40,000$76.5K+$61.8K400.0%
STATE STREET CORP393,802+14,701$602.5K+$45.2K3.9%
CITIGROUP INC13,471+11,536$20.6K+$17.8K596.2%
RAYMOND JAMES FINANCIAL INC103,856+2,600$158.9K+$10.1K2.6%
STIFEL FINANCIAL CORP50,294+2,327$76.9K+$6.4K4.8%
JPMORGAN CHASE & CO2,926+1,387$4.5K+$2.2K90.1%

Reduced(45)

ManagerSharesΔ SharesValueΔ Value% Δ
WELLS FARGO & COMPANY/MN3,100-2,800$455.2K-$382.5K-47.5%
Atom Investors LP104,396-226,171$159.7K-$326.2K-68.4%
Taylor Frigon Capital Management LLC869,227-95,483$1.3M-$88.2K-9.9%
CITADEL ADVISORS LLC174,215-64,773$266.5K-$84.8K-27.1%
JANE STREET GROUP, LLC74,300-34,847$113.7K-$46.8K-31.9%
ROTHSCHILD INVESTMENT LLC143,600-32,800$219.7K-$39.6K-18.6%
NORTHERN TRUST CORP658,9060$1.0M+$39.5K0.0%
BANK OF AMERICA CORP /DE/8,580-17,830$13.1K-$25.7K-67.5%
Yelin Lapidot Holdings Management Ltd.318,8520$487.8K+$19.1K0.0%
DAFNA Capital Management LLC272,4020$416.8K+$16.3K0.0%
MORGAN STANLEY1,009,701-50,036$1.5M-$13.0K-4.7%
R Squared Ltd29,650-8,571$45.4K-$10.8K-22.4%
MATRIX ASSET ADVISORS INC/NY93,8330$143.6K+$5.6K0.0%
SCHNIEDERS CAPITAL MANAGEMENT, LLC.90,0000$137.7K+$5.4K0.0%
Kingsview Wealth Management, LLC83,1790$127.3K+$5.0K0.0%
EAGLE ROCK INVESTMENT COMPANY, LLC71,2120$109.0K+$4.3K0.0%
GOLDMAN SACHS GROUP INC72,008-299$110.2K+$3.9K-0.4%
EWA, LLC59,563-315$91.1K+$3.1K-0.5%
SUSQUEHANNA INTERNATIONAL GROUP, LLP14,439-2,663$22.1K-$3.0K-15.6%
GEODE CAPITAL MANAGEMENT, LLC50,3950$77.1K+$3.0K0.0%
Secure Asset Management, LLC40,0000$61.2K-$2.8K0.0%
ADVISOR GROUP HOLDINGS, INC.32,345-240$49.5K+$2.5K-0.7%
IEQ CAPITAL, LLC40,0000$61.2K+$2.4K0.0%
TWO SIGMA ADVISERS, LP248,884-8,900$380.8K+$1.9K-3.5%
Calamos Wealth Management LLC29,5000$45.1K+$1.8K0.0%
Joel Isaacson & Co., LLC12,0000$18.4K+$7200.0%
GSG Advisors LLC10,2450$15.7K-$7170.0%
Vanguard Personalized Indexing Management, LLC11,6900$17.9K+$7020.0%
Mariner, LLC11,6900$17.8K+$6340.0%
Stockman Wealth Management, Inc.10,0000$15.3K+$6000.0%
LPL Financial LLC17,835-1,043$27.3K-$463-5.5%
Steward Partners Investment Advisory, LLC5,2020$8.0K+$3120.0%
Sound Income Strategies, LLC5000$1.2K+$2200.0%
PNC Financial Services Group, Inc.2,8000$4.3K+$1680.0%
EASTERN BANK2,0000$3.1K+$1200.0%
JONES FINANCIAL COMPANIES LLLP2000$306+$300.0%
N.E.W. Advisory Services LLC4000$612+$240.0%
Bernard Wealth Management Corp.4000$612+$240.0%
C M BIDWELL & ASSOCIATES LTD3580$548+$220.0%
SBI Securities Co., Ltd.338-1$517+$19-0.3%
Addison Advisors LLC2670$409+$160.0%
Janney Montgomery Scott LLC17,200-10,000$26-$14-36.8%
PHILADELPHIA TRUST CO15,0000$23+$10.0%
BNP PARIBAS ARBITRAGE, SNC30$5+$10.0%
Cambridge Investment Research Advisors, Inc.11,2500$17$00.0%

Sold Out(11)

ManagerSharesΔ SharesValueΔ Value% Δ
MACQUARIE GROUP LTD0-1,020,000$0-$1.5M
Squarepoint Ops LLC0-171,544$0-$252.2K
MILLENNIUM MANAGEMENT LLC0-141,033$0-$207.3K
Kestra Advisory Services, LLC0-21,500$0-$31.6K
Royal Bank of Canada0-14,600$0-$26.0K
Rock Springs Capital Management LP0-13,430$0-$19.7K
Glenmede Investment Management, LP0-12,000$0-$17.6K
Koesten, Hirschmann & Crabtree, INC.0-100$0-$147
Federation des caisses Desjardins du Quebec0-30$0-$44
COMMONWEALTH EQUITY SERVICES, LLC0-11,706$0-$17
SIMPLEX TRADING, LLC0-8,062$0-$11

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
SILVERARC CAPITAL MANAGEMENT, LLC3,479,805$5.3M+168,6405.1%
RENAISSANCE TECHNOLOGIES LLC1,456,900$2.2M+51,5653.7%
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.1,020,000$1.6M+1,020,000
MORGAN STANLEY1,009,701$1.5M-50,036-4.7%
Taylor Frigon Capital Management LLC869,227$1.3M-95,483-9.9%
NORTHERN TRUST CORP658,906$1.0M00.0%
STATE STREET CORP393,802$602.5K+14,7013.9%
UBS Group AG350,461$536.2K+53,86218.1%
Yelin Lapidot Holdings Management Ltd.318,852$487.8K00.0%
Stonepine Capital Management, LLC305,400$467.3K+305,400
TWO SIGMA INVESTMENTS, LP303,943$465.0K+106,06853.6%
WELLS FARGO & COMPANY/MN3,100$455.2K-2,800-47.5%
DAFNA Capital Management LLC272,402$416.8K00.0%
TWO SIGMA ADVISERS, LP248,884$380.8K-8,900-3.5%
CITADEL ADVISORS LLC174,215$266.5K-64,773-27.1%
ROTHSCHILD INVESTMENT LLC143,600$219.7K-32,800-18.6%
MARSHALL WACE, LLP106,304$162.6K+61,202135.7%
Atom Investors LP104,396$159.7K-226,171-68.4%
RAYMOND JAMES FINANCIAL INC103,856$158.9K+2,6002.6%
MATRIX ASSET ADVISORS INC/NY93,833$143.6K00.0%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for CGEN against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.