New Positions
16 managers initiated
Top five by reported value
- LAZARD ASSET MANAGEMENT LLC$699.1K
- Potomac Capital Management, Inc.$489.0K
- Atom Investors LP$301.0K
- Jain Global LLC$140.0K
- Point72 Asset Management, L.P.$102.8K
Codexis Inc NASDAQ NMS - GLOBAL MARKET:CDXS
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
16 new50 added60 reduced22 exited
Total Institutional Holders
125
as of 2025-12-31
Top Holder
abrdn plc
$13.0M
Largest QoQ Increase
abrdn plc
+3,874,436 sh
Largest QoQ Decrease
Opaleye Management Inc.
-6,005,262 sh
New Positions(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| LAZARD ASSET MANAGEMENT LLC | 428,921 | +428,921 | $699.1K | +$699.1K | — |
| Potomac Capital Management, Inc. | 300,000 | +300,000 | $489.0K | +$489.0K | — |
| Atom Investors LP | 184,655 | +184,655 | $301.0K | +$301.0K | — |
| Jain Global LLC | 85,900 | +85,900 | $140.0K | +$140.0K | — |
| Point72 Asset Management, L.P. | 63,089 | +63,089 | $102.8K | +$102.8K | — |
| EVERGREEN CAPITAL MANAGEMENT LLC | 29,000 | +29,000 | $47.3K | +$47.3K | — |
| Persistent Asset Partners Ltd | 27,813 | +27,813 | $45.3K | +$45.3K | — |
| GUGGENHEIM CAPITAL LLC | 27,355 | +27,355 | $44.6K | +$44.6K | — |
| Navalign, LLC | 15,340 | +15,340 | $25.0K | +$25.0K | — |
| GAMCO INVESTORS, INC. ET AL | 10,000 | +10,000 | $16.3K | +$16.3K | — |
| Caitong International Asset Management Co., Ltd | 9,395 | +9,395 | $15.3K | +$15.3K | — |
| Torren Management, LLC | 3,801 | +3,801 | $6.2K | +$6.2K | — |
| SIMPLEX TRADING, LLC | 824 | +824 | $1.3K | +$1.3K | — |
| HARBOUR INVESTMENTS, INC. | 501 | +501 | $817 | +$817 | — |
| Sunbelt Securities, Inc. | 30 | +30 | $49 | +$49 | — |
| Allworth Financial LP | 6 | +6 | $10 | +$10 | — |
Added To(50)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| BlackRock, Inc. | 7,395,740 | +251,792 | $12.1M | -$5.4M | 3.5% |
| VANGUARD GROUP INC | 4,941,542 | +271,727 | $8.1M | -$3.3M | 5.8% |
| abrdn plc | 7,966,498 | +3,874,436 | $13.0M | +$3.0M | 94.7% |
| PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 2,568,359 | +1,932,814 | $4.2M | +$2.6M | 304.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 2,026,006 | +33,602 | $3.3M | -$1.6M | 1.7% |
| STATE STREET CORP | 1,603,510 | +62,756 | $2.6M | -$1.1M | 4.1% |
| D. E. Shaw & Co., Inc. | 628,291 | +454,486 | $1.0M | +$600.0K | 261.5% |
| AMERIPRISE FINANCIAL INC | 3,793,574 | +1,019,928 | $6.2M | -$584.2K | 36.8% |
| NORTHERN TRUST CORP | 645,296 | +22 | $1.1M | -$522.6K | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 737,485 | +426,999 | $1.2M | +$444.5K | 137.5% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 294,653 | +264,069 | $480.3K | +$405.7K | 863.4% |
| FMR LLC | 641,926 | +57,559 | $1.0M | -$379.5K | 9.8% |
| JANE STREET GROUP, LLC | 299,930 | +249,672 | $488.9K | +$366.3K | 496.8% |
| Assenagon Asset Management S.A. | 566,547 | +332,594 | $923.5K | +$352.6K | 142.2% |
| Private Advisor Group, LLC | 654,581 | +93,168 | $1.1M | -$302.9K | 16.6% |
| MORGAN STANLEY | 431,140 | +234,514 | $702.8K | +$223.0K | 119.3% |
| Stonepine Capital Management, LLC | 256,106 | +167,842 | $417.5K | +$202.1K | 190.2% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 274,898 | +24,166 | $448.1K | -$163.7K | 9.6% |
| CITADEL ADVISORS LLC | 516,877 | +230,746 | $842.5K | +$144.4K | 80.6% |
| PERKINS CAPITAL MANAGEMENT INC | 529,500 | +221,800 | $863.1K | +$112.3K | 72.1% |
| DEUTSCHE BANK AG\ | 51,406 | +49,759 | $83.8K | +$79.8K | 3021.2% |
| XTX Topco Ltd | 74,558 | +57,254 | $121.5K | +$79.3K | 330.9% |
| BARCLAYS PLC | 253,639 | +29,147 | $618.9K | +$71.1K | 13.0% |
| UBS Group AG | 809,520 | +287,137 | $1.3M | +$44.9K | 55.0% |
| TWO SIGMA ADVISERS, LP | 59,400 | +31,900 | $96.8K | +$29.7K | 116.0% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 41,398 | +2,656 | $67.5K | -$27.1K | 6.8% |
| JPMORGAN CHASE & CO | 40,977 | +2,641 | $66.8K | -$26.7K | 6.9% |
| Quadrature Capital Ltd | 54,435 | +27,509 | $88.7K | +$23.2K | 102.2% |
| Russell Investments Group, Ltd. | 59,051 | +10,608 | $96.3K | -$21.9K | 21.9% |
| Tower Research Capital LLC (TRC) | 27,409 | +17,435 | $44.7K | +$20.3K | 174.8% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 32,751 | +3,285 | $53.4K | -$18.5K | 11.1% |
| Krilogy Financial LLC | 30,101 | +72 | $46.7K | -$17.9K | 0.2% |
| Invesco Ltd. | 174,590 | +51,454 | $284.6K | -$15.9K | 41.8% |
| WELLS FARGO & COMPANY/MN | 122,030 | +45,447 | $198.9K | +$12.0K | 59.3% |
| Aigen Investment Management, LP | 17,629 | +1,799 | $28.7K | -$9.9K | 11.4% |
| TWO SIGMA INVESTMENTS, LP | 39,804 | +17,059 | $64.9K | +$9.4K | 75.0% |
| ProShare Advisors LLC | 20,214 | +2,999 | $32.9K | -$9.1K | 17.4% |
| VICTORY CAPITAL MANAGEMENT INC | 10,081 | +9 | $16.4K | -$8.1K | 0.1% |
| BANK OF AMERICA CORP /DE/ | 69,999 | +20,247 | $114.1K | -$7.3K | 40.7% |
| BNP PARIBAS ARBITRAGE, SNC | 20,668 | +4,060 | $33.7K | -$6.8K | 24.4% |
| FEDERATED HERMES, INC. | 347,640 | +113,393 | $566.7K | -$4.9K | 48.4% |
| State of Wyoming | 16,870 | +3,768 | $27.5K | -$4.5K | 28.8% |
| GAMMA Investing LLC | 2,604 | +1,631 | $4.2K | +$1.9K | 167.6% |
| Mirae Asset Global Investments Co., Ltd. | 4,389 | +899 | $7.2K | -$1.4K | 25.8% |
| PNC Financial Services Group, Inc. | 876 | +799 | $1.4K | +$1.2K | 1037.7% |
| Sterling Capital Management LLC | 1,471 | +273 | $2.4K | -$525 | 22.8% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 150,908 | +50,000 | $246.0K | -$236 | 49.5% |
| SG Americas Securities, LLC | 50,290 | +28,754 | $82 | +$29 | 133.5% |
| ACADIAN ASSET MANAGEMENT LLC | 88,376 | +28,011 | $142 | -$4 | 46.4% |
| AMALGAMATED BANK | 2,803 | +23 | $5 | -$2 | 0.8% |
Reduced(60)
Sold Out(22)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| abrdn plc | 7,966,498 | $13.0M | +3,874,436 | 94.7% |
| BlackRock, Inc. | 7,395,740 | $12.1M | +251,792 | 3.5% |
| Opaleye Management Inc. | 6,789,738 | $11.1M | -6,005,262 | -46.9% |
| VANGUARD GROUP INC | 4,941,542 | $8.1M | +271,727 | 5.8% |
| Nantahala Capital Management, LLC | 3,990,169 | $6.5M | -40,450 | -1.0% |
| Telemark Asset Management, LLC | 3,846,411 | $6.3M | -153,589 | -3.8% |
| AMERIPRISE FINANCIAL INC | 3,793,574 | $6.2M | +1,019,928 | 36.8% |
| MILLENNIUM MANAGEMENT LLC | 3,135,192 | $5.1M | -932,367 | -22.9% |
| PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 2,568,359 | $4.2M | +1,932,814 | 304.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 2,026,006 | $3.3M | +33,602 | 1.7% |
| STATE STREET CORP | 1,603,510 | $2.6M | +62,756 | 4.1% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,135,190 | $1.9M | -29,656 | -2.5% |
| UBS Group AG | 809,520 | $1.3M | +287,137 | 55.0% |
| FRANKLIN RESOURCES INC | 740,558 | $1.2M | -15,600 | -2.1% |
| RENAISSANCE TECHNOLOGIES LLC | 737,485 | $1.2M | +426,999 | 137.5% |
| GOLDMAN SACHS GROUP INC | 718,109 | $1.2M | -6,146 | -0.8% |
| Private Advisor Group, LLC | 654,581 | $1.1M | +93,168 | 16.6% |
| NORTHERN TRUST CORP | 645,296 | $1.1M | +22 | 0.0% |
| FMR LLC | 641,926 | $1.0M | +57,559 | 9.8% |
| D. E. Shaw & Co., Inc. | 628,291 | $1.0M | +454,486 | 261.5% |
New & Closed Positions this quarter
Closed Positions
22 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for CDXS against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.