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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · CALC

CalciMedica Inc NASDAQ NMS - GLOBAL MARKET:CALC

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

6 new5 added19 reduced8 exited

New Positions(6)

ManagerSharesΔ SharesValueΔ Value% Δ
BOOTHBAY FUND MANAGEMENT, LLC76,855+76,855$506.5K+$506.5K
PVG ASSET MANAGEMENT CORP45,830+45,830$302.0K+$302.0K
JANE STREET GROUP, LLC19,203+19,203$126.5K+$126.5K
TritonPoint Partners, LLC15,119+15,119$99.6K+$99.6K
NORTHERN TRUST CORP12,530+12,530$82.6K+$82.6K
WELLS FARGO & COMPANY/MN10+10$66+$66

Added To(5)

ManagerSharesΔ SharesValueΔ Value% Δ
VANGUARD GROUP INC407,801+31,177$2.7M+$1.6M8.3%
RENAISSANCE TECHNOLOGIES LLC88,300+18,300$581.9K+$366.6K26.1%
GEODE CAPITAL MANAGEMENT, LLC99,787+935$657.6K+$359.1K0.9%
Summit Financial, LLC35,484+10,392$233.8K+$156.6K41.4%
UBS Group AG1,100+1,083$7.2K+$7.2K6370.6%

Reduced(19)

ManagerSharesΔ SharesValueΔ Value% Δ
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)1,300,0000$8.6M+$4.6M0.0%
Soleus Capital Management, L.P.683,9040$4.5M+$2.4M0.0%
Aisling Capital Management LP521,1140$3.4M+$1.8M0.0%
MERITAGE PORTFOLIO MANAGEMENT61,5390$405.5K+$216.3K0.0%
Stonehage Fleming Financial Services Holdings Ltd53,7030$353.9K+$188.7K0.0%
ENVESTNET ASSET MANAGEMENT INC63,186-13,519$416.4K+$180.5K-17.6%
180 WEALTH ADVISORS, LLC31,850-10,850$209.9K+$78.6K-25.4%
Atria Investments, Inc28,781-9,305$189.7K+$72.5K-24.4%
Sound View Wealth Advisors Group, LLC20,1000$132.5K+$70.6K0.0%
Cetera Investment Advisers22,290-3,075$146.9K+$68.9K-12.1%
J. Goldman & Co LP18,9000$124.6K+$66.4K0.0%
FIRST MANHATTAN CO13,2260$87.2K+$46.5K0.0%
Rockefeller Capital Management L.P.10,0000$65.9K+$35.1K0.0%
BANK OF AMERICA CORP /DE/9,027-5$59.5K+$31.7K-0.1%
MILLENNIUM MANAGEMENT LLC14,855-19,533$97.9K-$6.0K-56.8%
ADVISOR GROUP HOLDINGS, INC.107-931$705-$2.5K-89.7%
BROWN BROTHERS HARRIMAN & CO3080$2.0K+$1.1K0.0%
SBI Securities Co., Ltd.90-32$593+$218-26.2%
BNP PARIBAS ARBITRAGE, SNC190$125+$670.0%

Sold Out(8)

ManagerSharesΔ SharesValueΔ Value% Δ
Sheets Smith Investment Management0-51,100$0-$157.2K
CI Private Wealth, LLC0-38,000$0-$60.8K
TRITONPOINT WEALTH, LLC0-15,119$0-$46.5K
XTX Topco Ltd0-15,345$0-$46.3K
CITIGROUP INC0-4,927$0-$15.2K
MORGAN STANLEY0-856$0-$2.6K
Tower Research Capital LLC (TRC)0-666$0-$2.0K
BARCLAYS PLC0-57$0-$175

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)1,300,000$8.6M00.0%
Soleus Capital Management, L.P.683,904$4.5M00.0%
Aisling Capital Management LP521,114$3.4M00.0%
VANGUARD GROUP INC407,801$2.7M+31,1778.3%
GEODE CAPITAL MANAGEMENT, LLC99,787$657.6K+9350.9%
RENAISSANCE TECHNOLOGIES LLC88,300$581.9K+18,30026.1%
BOOTHBAY FUND MANAGEMENT, LLC76,855$506.5K+76,855
ENVESTNET ASSET MANAGEMENT INC63,186$416.4K-13,519-17.6%
MERITAGE PORTFOLIO MANAGEMENT61,539$405.5K00.0%
Stonehage Fleming Financial Services Holdings Ltd53,703$353.9K00.0%
PVG ASSET MANAGEMENT CORP45,830$302.0K+45,830
Summit Financial, LLC35,484$233.8K+10,39241.4%
180 WEALTH ADVISORS, LLC31,850$209.9K-10,850-25.4%
Atria Investments, Inc28,781$189.7K-9,305-24.4%
Cetera Investment Advisers22,290$146.9K-3,075-12.1%
Sound View Wealth Advisors Group, LLC20,100$132.5K00.0%
JANE STREET GROUP, LLC19,203$126.5K+19,203
J. Goldman & Co LP18,900$124.6K00.0%
TritonPoint Partners, LLC15,119$99.6K+15,119
MILLENNIUM MANAGEMENT LLC14,855$97.9K-19,533-56.8%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for CALC against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.