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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Aprea Therapeutics, Inc. (APRE)

NCM · Biotechnology

$0.61-0.01 (-1.76%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$7.6M
P/E (TTM)
EPS
$-1.46
Div Yield
52W Range
$0.55–$1.91
Beta
1.56

Company overview

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.

Peers in Biotechnology

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Recent press releases

April 2026

3 months agoS-3Healthcare

APRE files S-3 for large shareholders to sell up to 74 million shares

APREAprea Therapeutics, Inc.

# 📄 What This Document Is 📜 This is an S-3 Registration Statement, a major SEC filing that tells investors exactly what shares are available and under what conditions. Unlike a typical earnings report, this document is focused entirely on the potential *sale* of company stock and warrants by exist

Read summaryView on SEC EDGAR
3 months agoPRE 14AHealthcare

Aprea proposes reverse stock split for shareholders at 2026 annual meeting

APREAprea Therapeutics, Inc.

# 🧾 What This Document Is 📄 This is a Preliminary Proxy Statement (PRE 14A), which is a highly technical document filed with the SEC. Essentially, it’s the official homework assignment for the company's shareholders. It informs you about the upcoming 2026 Annual Meeting of Stockholders and outline

Read summaryView on SEC EDGAR
3 months ago8-KHealthcare

Aprea Therapeutics, Inc. — 8-K Filing

APREAprea Therapeutics, Inc.

# 🧾 What This Document Is This is a Form 8-K filing, which companies use to announce major events to investors. Attached is a press release announcing that Aprea Therapeutics has closed a **$30 million private funding round**. This isn't a regular stock sale to the public; it was a direct deal with

Read summaryView on SEC EDGAR

March 2026

4 months ago8-KHealthcare

Aprea Therapeutics, Inc. — 8-K Filing

APREAprea Therapeutics, Inc.

# 🧾 What This Document Is This is an 8-K filing from **Aprea Therapeutics, Inc. (APRE)**. It contains the full legal contract (Exhibit 10.1) for a **private investment deal**. Essentially, the company is selling stock and warrants directly to a group of investors to raise money. This isn't a public

Read summaryView on SEC EDGAR

SEC filings

All filings →
4 recent filings shown in the timeline above. View all SEC filings →

Aprea Therapeutics, Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
370,541 sh-31.3%
340,139 sh● NEW
58,086 sh-63.3%
270,000 sh0.0%
205,760 sh0.0%
120,651 sh● NEW
51,041 sh● NEW
46,621 sh● NEW

People at Aprea Therapeutics, Inc.

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Quarterly financials

Full financials →
Revenue trend
03/25
NI -$3.9M
06/25
NI -$3.2M
09/25
NI -$3.0M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-0.47
Prior: $-0.53
Revenue sparkline
APRE (NCM) Stock Quote, Press Releases & SEC... | Cayman Journal | Cayman Journal