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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Sionna Therapeutics, Inc. (SION)

NGM · Biotechnology

$46.55+1.17 (+2.58%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$2.10B
P/E (TTM)
EPS
$-1.91
Div Yield
52W Range
$16.38–$51.56
Beta

Company overview

Next earnings: 2026-08-10(13d)

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial. The company was formerly known as Sling Therapeutics, Inc. and changed its name to Sionna Therapeutics, Inc. in July 2021. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

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Recent press releases

Sionna Therapeutics, Inc. has not issued a press release in this window.

SEC filings

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Sionna Therapeutics, Inc. has not filed an SEC document in this window.

Sionna Therapeutics, Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
9,905,045 sh-5.2%
6,744,962 sh0.0%
1,087,325 sh+2926.8%
3,561,655 sh-3.9%
3,195,181 sh0.0%
2,478,030 sh0.0%
1,291,599 sh+52.9%
639,045 sh● NEW

People at Sionna Therapeutics, Inc.

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Quarterly financials

Full financials →
Revenue trend
03/25
NI -$16.5M
06/25
NI -$18.1M
09/25
NI -$20.3M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-0.46
Prior: $-410.00
Revenue sparkline