New Positions
8 managers initiated
Top five by reported value
Unicycive Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:UNCY
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
8 new8 added19 reduced3 exited
Total Institutional Holders
35
as of 2025-12-31
Top Holder
Vivo Capital, LLC
$10.3M
Largest QoQ Increase
MILLENNIUM MANAGEMENT LLC
+1,014,843 sh
Largest QoQ Decrease
Squarepoint Ops LLC
-62,022 sh
New Positions(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 1,014,843 | +1,014,843 | $5.9M | +$5.9M | — |
| CANTOR FITZGERALD, L. P. | 200,000 | +200,000 | $1.2M | +$1.2M | — |
| Dauntless Investment Group, LLC | 89,415 | +89,415 | $515.9K | +$515.9K | — |
| OMERS ADMINISTRATION Corp | 78,200 | +78,200 | $451.2K | +$451.2K | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 51,231 | +51,231 | $295.6K | +$295.6K | — |
| Quadrature Capital Ltd | 39,114 | +39,114 | $225.7K | +$225.7K | — |
| JANE STREET GROUP, LLC | 20,900 | +20,900 | $120.6K | +$120.6K | — |
| Tower Research Capital LLC (TRC) | 1,920 | +1,920 | $11.1K | +$11.1K | — |
Added To(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 788,587 | +129,709 | $4.6M | +$1.7M | 19.7% |
| CITADEL ADVISORS LLC | 269,201 | +227,527 | $1.6M | +$1.4M | 546.0% |
| BNP PARIBAS ARBITRAGE, SNC | 99,742 | +99,687 | $575.5K | +$575.3K | 181249.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 171,290 | +45,563 | $989.2K | +$441.0K | 36.2% |
| MORGAN STANLEY | 46,584 | +35,972 | $268.8K | +$222.5K | 339.0% |
| STATE STREET CORP | 65,227 | +10,400 | $376.4K | +$137.3K | 19.0% |
| UBS Group AG | 19,905 | +14,460 | $114.9K | +$91.1K | 265.6% |
| NORTHERN TRUST CORP | 35,937 | +3,238 | $207.4K | +$64.8K | 9.9% |
Reduced(19)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Vivo Capital, LLC | 1,789,916 | 0 | $10.3M | +$2.5M | 0.0% |
| Octagon Capital Advisors LP | 1,000,000 | 0 | $5.8M | +$1.4M | 0.0% |
| Nantahala Capital Management, LLC | 939,202 | 0 | $5.4M | +$1.3M | 0.0% |
| GREAT POINT PARTNERS LLC | 796,558 | 0 | $4.6M | +$1.1M | 0.0% |
| Logos Global Management LP | 473,563 | 0 | $2.7M | +$667.7K | 0.0% |
| Squarepoint Ops LLC | 55,305 | -62,022 | $319.1K | -$192.4K | -52.9% |
| ACUTA CAPITAL PARTNERS, LLC | 59,985 | 0 | $346.1K | +$84.6K | 0.0% |
| BlackRock, Inc. | 36,355 | 0 | $209.8K | +$51.3K | 0.0% |
| XTX Topco Ltd | 35,405 | -2,418 | $204.3K | +$39.4K | -6.4% |
| CITIGROUP INC | 228 | -6,464 | $1.3K | -$27.9K | -96.6% |
| Chicago Partners Investment Group LLC | 22,413 | -4,548 | $155.1K | +$27.8K | -16.9% |
| BANK OF AMERICA CORP /DE/ | 152 | -675 | $877 | -$2.7K | -81.6% |
| SBI Securities Co., Ltd. | 558 | -2 | $3.2K | +$778 | -0.3% |
| Rockefeller Capital Management L.P. | 500 | 0 | $2.9K | +$705 | 0.0% |
| TFC Financial Management, Inc. | 300 | 0 | $1.7K | +$423 | 0.0% |
| HARBOUR INVESTMENTS, INC. | 100 | 0 | $577 | +$141 | 0.0% |
| BARCLAYS PLC | 80 | 0 | $382 | +$33 | 0.0% |
| Bogart Wealth, LLC | 6 | 0 | $35 | +$9 | 0.0% |
| DANSKE BANK A/S | 1 | 0 | $6 | +$2 | 0.0% |
Sold Out(3)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GOLDMAN SACHS GROUP INC | 0 | -45,200 | $0 | -$197.1K | — |
| Cubist Systematic Strategies, LLC | 0 | -23,947 | $0 | -$104.4K | — |
| Fortitude Family Office, LLC | 0 | -107 | $0 | -$467 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Vivo Capital, LLC | 1,789,916 | $10.3M | 0 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 1,014,843 | $5.9M | +1,014,843 | — |
| Octagon Capital Advisors LP | 1,000,000 | $5.8M | 0 | 0.0% |
| Nantahala Capital Management, LLC | 939,202 | $5.4M | 0 | 0.0% |
| GREAT POINT PARTNERS LLC | 796,558 | $4.6M | 0 | 0.0% |
| VANGUARD GROUP INC | 788,587 | $4.6M | +129,709 | 19.7% |
| Logos Global Management LP | 473,563 | $2.7M | 0 | 0.0% |
| CITADEL ADVISORS LLC | 269,201 | $1.6M | +227,527 | 546.0% |
| CANTOR FITZGERALD, L. P. | 200,000 | $1.2M | +200,000 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 171,290 | $989.2K | +45,563 | 36.2% |
| BNP PARIBAS ARBITRAGE, SNC | 99,742 | $575.5K | +99,687 | 181249.1% |
| Dauntless Investment Group, LLC | 89,415 | $515.9K | +89,415 | — |
| OMERS ADMINISTRATION Corp | 78,200 | $451.2K | +78,200 | — |
| STATE STREET CORP | 65,227 | $376.4K | +10,400 | 19.0% |
| ACUTA CAPITAL PARTNERS, LLC | 59,985 | $346.1K | 0 | 0.0% |
| Squarepoint Ops LLC | 55,305 | $319.1K | -62,022 | -52.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 51,231 | $295.6K | +51,231 | — |
| MORGAN STANLEY | 46,584 | $268.8K | +35,972 | 339.0% |
| Quadrature Capital Ltd | 39,114 | $225.7K | +39,114 | — |
| BlackRock, Inc. | 36,355 | $209.8K | 0 | 0.0% |
New & Closed Positions this quarter
Closed Positions
3 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for UNCY against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.