New Positions
10 managers initiated
Top five by reported value
TScan Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:TCRX
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
10 new17 added33 reduced25 exited
Total Institutional Holders
60
as of 2025-12-31
Top Holder
Lynx1 Capital Management LP
$8.0M
Largest QoQ Increase
abrdn plc
+430,421 sh
Largest QoQ Decrease
Propel Bio Management, LLC
-1,932,304 sh
New Positions(10)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| JACOBS LEVY EQUITY MANAGEMENT, INC | 188,152 | +188,152 | $188.2K | +$188.2K | — |
| D. E. Shaw & Co., Inc. | 69,427 | +69,427 | $69.4K | +$69.4K | — |
| PANAGORA ASSET MANAGEMENT INC | 25,256 | +25,256 | $25.3K | +$25.3K | — |
| TWO SIGMA SECURITIES, LLC | 15,942 | +15,942 | $15.9K | +$15.9K | — |
| Point72 Asset Management, L.P. | 14,512 | +14,512 | $14.5K | +$14.5K | — |
| MIZUHO SECURITIES USA LLC | 10,000 | +10,000 | $10.1K | +$10.1K | — |
| GSA CAPITAL PARTNERS LLP | 226,164 | +226,164 | $226 | +$226 | — |
| ACADIAN ASSET MANAGEMENT LLC | 29,538 | +29,538 | $28 | +$28 | — |
| HRT FINANCIAL LP | 26,581 | +26,581 | $26 | +$26 | — |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 8 | +8 | $8 | +$8 | — |
Added To(17)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Lynx1 Capital Management LP | 8,019,148 | +161,801 | $8.0M | -$6.3M | 2.0% |
| VANGUARD GROUP INC | 2,475,733 | +157,817 | $2.5M | -$1.7M | 6.8% |
| abrdn plc | 1,785,241 | +430,421 | $1.8M | -$680.5K | 31.8% |
| RENAISSANCE TECHNOLOGIES LLC | 1,141,069 | +311,150 | $1.1M | -$369.4K | 37.5% |
| MARSHALL WACE, LLP | 339,240 | +292,610 | $339.2K | +$254.4K | 627.5% |
| JANE STREET GROUP, LLC | 388,284 | +306,968 | $388.3K | +$240.3K | 377.5% |
| XTX Topco Ltd | 219,001 | +201,375 | $219.0K | +$186.9K | 1142.5% |
| TWO SIGMA ADVISERS, LP | 353,900 | +65,100 | $353.9K | -$171.7K | 22.5% |
| STATE STREET CORP | 207,313 | +10,000 | $207.3K | -$151.8K | 5.1% |
| TWO SIGMA INVESTMENTS, LP | 651,179 | +231,775 | $651.2K | -$112.1K | 55.3% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 216,133 | +136,373 | $216.1K | +$71.0K | 171.0% |
| UBS Group AG | 55,198 | +44,125 | $55.2K | +$35.0K | 398.5% |
| LPL Financial LLC | 22,500 | +1,000 | $22.5K | -$16.6K | 4.7% |
| BARCLAYS PLC | 21,178 | +2,101 | $30.7K | -$4.0K | 11.0% |
| PRUDENTIAL FINANCIAL INC | 24,400 | +12,900 | $24.4K | +$3.5K | 112.2% |
| FEDERATED HERMES, INC. | 4,989 | +2,808 | $5.0K | +$1.0K | 128.7% |
| SBI Securities Co., Ltd. | 392 | +180 | $392 | +$6 | 84.9% |
Reduced(33)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| BVF INC/IL | 5,226,074 | 0 | $5.2M | -$4.3M | 0.0% |
| BlackRock, Inc. | 1,848,695 | -534,069 | $1.8M | -$2.5M | -22.4% |
| BAKER BROS. ADVISORS LP | 2,784,792 | 0 | $2.8M | -$2.3M | 0.0% |
| MORGAN STANLEY | 225,829 | -621,708 | $225.8K | -$1.3M | -73.3% |
| TANG CAPITAL MANAGEMENT LLC | 46,131 | -553,869 | $46.1K | -$1.0M | -92.3% |
| Deer Management Co. LLC | 1,245,504 | 0 | $1.2M | -$1.0M | 0.0% |
| CITADEL ADVISORS LLC | 162,877 | -227,870 | $162.9K | -$548.3K | -58.3% |
| DC Funds, LP | 630,000 | 0 | $630.0K | -$516.6K | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 562,153 | -5,504 | $562.4K | -$471.2K | -1.0% |
| MILLENNIUM MANAGEMENT LLC | 403,618 | -62,468 | $403.6K | -$444.7K | -13.4% |
| JPMORGAN CHASE & CO | 33,349 | -204,401 | $33.3K | -$399.4K | -86.0% |
| BANK OF AMERICA CORP /DE/ | 38,700 | -184,324 | $38.7K | -$367.2K | -82.6% |
| GOLDMAN SACHS GROUP INC | 86,903 | -44,077 | $86.9K | -$151.5K | -33.6% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 115,400 | -25,000 | $115.4K | -$140.1K | -17.8% |
| BROWN BROTHERS HARRIMAN & CO | 143,051 | 0 | $143.1K | -$117.3K | 0.0% |
| STIFEL FINANCIAL CORP | 72,400 | -25,000 | $72.4K | -$104.9K | -25.7% |
| DIMENSIONAL FUND ADVISORS LP | 74,467 | -12,849 | $74.5K | -$84.2K | -14.7% |
| NORTHERN TRUST CORP | 98,198 | -350 | $98.2K | -$81.2K | -0.3% |
| LETKO, BROSSEAU & ASSOCIATES INC | 95,875 | 0 | $95.9K | -$78.6K | 0.0% |
| DC Investments Management, LLC | 35,563 | 0 | $35.6K | -$29.2K | 0.0% |
| BNP PARIBAS ARBITRAGE, SNC | 26,360 | -3,510 | $26.4K | -$28.0K | -11.8% |
| Vanguard Personalized Indexing Management, LLC | 14,677 | -6,315 | $14.7K | -$23.5K | -30.1% |
| R Squared Ltd | 16,033 | -2,794 | $16.0K | -$18.2K | -14.8% |
| FMR LLC | 500 | -9,493 | $500 | -$17.7K | -95.0% |
| Neuberger Berman Group LLC | 18,400 | 0 | $18.4K | -$15.1K | 0.0% |
| Tower Research Capital LLC (TRC) | 6,766 | -4,349 | $6.8K | -$13.5K | -39.1% |
| NewEdge Wealth, LLC | 91,463 | 0 | $91.5K | -$12.3K | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 12,245 | 0 | $12.2K | -$9.6K | 0.0% |
| Aries Wealth Management | 10,000 | 0 | $10.0K | -$8.2K | 0.0% |
| Waldron Private Wealth LLC | 10,000 | 0 | $10.0K | -$8.2K | 0.0% |
| Royal Bank of Canada | 374 | -810 | $0 | -$1.0K | -68.4% |
| Rockefeller Capital Management L.P. | 200 | 0 | $200 | -$164 | 0.0% |
| Militia Capital Partners, LP | 102,100 | 0 | $185.8K | $0 | 0.0% |
Sold Out(25)
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Lynx1 Capital Management LP | 8,019,148 | $8.0M | +161,801 | 2.0% |
| BVF INC/IL | 5,226,074 | $5.2M | 0 | 0.0% |
| BAKER BROS. ADVISORS LP | 2,784,792 | $2.8M | 0 | 0.0% |
| VANGUARD GROUP INC | 2,475,733 | $2.5M | +157,817 | 6.8% |
| BlackRock, Inc. | 1,848,695 | $1.8M | -534,069 | -22.4% |
| abrdn plc | 1,785,241 | $1.8M | +430,421 | 31.8% |
| Deer Management Co. LLC | 1,245,504 | $1.2M | 0 | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 1,141,069 | $1.1M | +311,150 | 37.5% |
| TWO SIGMA INVESTMENTS, LP | 651,179 | $651.2K | +231,775 | 55.3% |
| DC Funds, LP | 630,000 | $630.0K | 0 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 562,153 | $562.4K | -5,504 | -1.0% |
| MILLENNIUM MANAGEMENT LLC | 403,618 | $403.6K | -62,468 | -13.4% |
| JANE STREET GROUP, LLC | 388,284 | $388.3K | +306,968 | 377.5% |
| TWO SIGMA ADVISERS, LP | 353,900 | $353.9K | +65,100 | 22.5% |
| MARSHALL WACE, LLP | 339,240 | $339.2K | +292,610 | 627.5% |
| MORGAN STANLEY | 225,829 | $225.8K | -621,708 | -73.3% |
| XTX Topco Ltd | 219,001 | $219.0K | +201,375 | 1142.5% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 216,133 | $216.1K | +136,373 | 171.0% |
| STATE STREET CORP | 207,313 | $207.3K | +10,000 | 5.1% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 188,152 | $188.2K | +188,152 | — |
New & Closed Positions this quarter
Closed Positions
25 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for TCRX against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.