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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Spruce Biosciences, Inc. (SPRB)

NCM · Biotechnology

$41.60-0.39 (-0.93%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$114.5M
P/E (TTM)
EPS
$-35.46
Div Yield
52W Range
$7.00–$675.00
Beta
3.21

Company overview

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.

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Recent press releases

Spruce Biosciences, Inc. has not issued a press release in this window.

SEC filings

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Spruce Biosciences, Inc. has not filed an SEC document in this window.

Spruce Biosciences, Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-06-30 · prior 2025-03-31

People at Spruce Biosciences, Inc.

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Quarterly financials

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Revenue trend
03/25
NI -$14.0M
06/25
NI -$2.1M
09/25
NI -$8.2M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-14.58
Prior: $-3.50
Revenue sparkline