New Positions
11 managers initiated
Top five by reported value
- ROYCE & ASSOCIATES LP$2.0M
- 1492 Capital Management LLC$973.0K
- POLEN CAPITAL MANAGEMENT LLC$101.5K
- XTX Topco Ltd$54.9K
- Quadrature Capital Ltd$54.4K
SOPHiA GENETICS SA NASDAQ NMS - GLOBAL MARKET:SOPH
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
11 new16 added15 reduced8 exited
Total Institutional Holders
42
as of 2025-12-31
Top Holder
GENERATION INVESTMENT MANAGEMENT LLP
$31.7M
Largest QoQ Increase
ROYCE & ASSOCIATES LP
+430,257 sh
Largest QoQ Decrease
MILLENNIUM MANAGEMENT LLC
-100,445 sh
New Positions(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| ROYCE & ASSOCIATES LP | 430,257 | +430,257 | $2.0M | +$2.0M | — |
| 1492 Capital Management LLC | 208,345 | +208,345 | $973.0K | +$973.0K | — |
| POLEN CAPITAL MANAGEMENT LLC | 21,738 | +21,738 | $101.5K | +$101.5K | — |
| XTX Topco Ltd | 11,760 | +11,760 | $54.9K | +$54.9K | — |
| Quadrature Capital Ltd | 11,649 | +11,649 | $54.4K | +$54.4K | — |
| PERKINS CAPITAL MANAGEMENT INC | 10,500 | +10,500 | $49.0K | +$49.0K | — |
| BANK OF AMERICA CORP /DE/ | 5,552 | +5,552 | $25.9K | +$25.9K | — |
| PNC Financial Services Group, Inc. | 370 | +370 | $1.7K | +$1.7K | — |
| United Financial Planning Group LLC | 170 | +170 | $794 | +$794 | — |
| FNY Investment Advisers, LLC | 16,010 | +16,010 | $74 | +$74 | — |
| ACADIAN ASSET MANAGEMENT LLC | 5,911 | +5,911 | $27 | +$27 | — |
Added To(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 83,000 | +52,200 | $387.6K | +$241.0K | 169.5% |
| UBS Group AG | 61,901 | +46,517 | $289.1K | +$215.8K | 302.4% |
| PRINCIPAL FINANCIAL GROUP INC | 1,399,442 | +8,230 | $6.5M | -$86.8K | 0.6% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 30,511 | +12,032 | $142.5K | +$54.5K | 65.1% |
| Archon Capital Management LLC | 441,413 | +14,342 | $2.1M | +$28.5K | 3.4% |
| MORGAN STANLEY | 48,047 | +6,513 | $224.4K | +$26.7K | 15.7% |
| Green Alpha Advisors, LLC | 45,660 | +4,444 | $213.2K | +$17.0K | 10.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 92,596 | +680 | $432.4K | -$5.1K | 0.7% |
| GOLDMAN SACHS GROUP INC | 28,660 | +1,453 | $133.8K | +$4.3K | 5.3% |
| ADVISOR GROUP HOLDINGS, INC. | 1,000 | +853 | $4.7K | +$4.0K | 580.3% |
| Pathstone Holdings, LLC | 32,203 | +88 | $150.4K | -$2.5K | 0.3% |
| ASSETMARK, INC | 4,687 | +566 | $21.9K | +$2.3K | 13.7% |
| Silverberg Bernstein Capital Management LLC | 47,815 | +1,100 | $223.3K | +$933 | 2.4% |
| SBI Securities Co., Ltd. | 41 | +40 | $191 | +$186 | 4000.0% |
| Russell Investments Group, Ltd. | 59 | +37 | $276 | +$171 | 168.2% |
| GSA CAPITAL PARTNERS LLP | 24,967 | +12,513 | $117 | +$58 | 100.5% |
Reduced(15)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| GENERATION INVESTMENT MANAGEMENT LLP | 6,789,560 | 0 | $31.7M | -$611.1K | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 125,458 | -100,445 | $585.9K | -$489.4K | -44.5% |
| AKRE CAPITAL MANAGEMENT LLC | 3,719,140 | 0 | $17.4M | -$334.7K | 0.0% |
| BANQUE PICTET & CIE SA | 2,208,280 | 0 | $10.3M | -$198.7K | 0.0% |
| Alta Wealth Advisors LLC | 1,409,160 | 0 | $6.6M | -$126.8K | 0.0% |
| FEDERATED HERMES, INC. | 187,677 | -22,323 | $876.5K | -$123.1K | -10.6% |
| Ensign Peak Advisors, Inc | 182,414 | -12,768 | $851.9K | -$77.2K | -6.5% |
| Rathbones Group Plc | 160,133 | -2,350 | $747.8K | -$25.6K | -1.4% |
| Pictet & Cie (Europe) SA | 255,200 | 0 | $1.2M | -$23.0K | 0.0% |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 203,334 | 0 | $949.6K | -$18.3K | 0.0% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,755 | -3,172 | $17.5K | -$15.4K | -45.8% |
| Royal Bank of Canada | 600 | -600 | $3.0K | -$1.0K | -50.0% |
| BlackRock, Inc. | 5,086 | 0 | $23.8K | -$457 | 0.0% |
| SIMPLEX TRADING, LLC | 31 | -995 | $144 | +$140 | -97.0% |
| Compagnie Lombard Odier SCmA | 1,055 | 0 | $4.9K | -$95 | 0.0% |
Sold Out(8)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| DIMENSIONAL FUND ADVISORS LP | 0 | -31,332 | $0 | -$148.2K | — |
| CITADEL ADVISORS LLC | 0 | -12,320 | $0 | -$58.6K | — |
| Squarepoint Ops LLC | 0 | -10,231 | $0 | -$48.7K | — |
| Savvy Advisors, Inc. | 0 | -10,000 | $0 | -$47.6K | — |
| Tower Research Capital LLC (TRC) | 0 | -491 | $0 | -$2.3K | — |
| PRINCIPAL SECURITIES, INC. | 0 | -394 | $0 | -$1.9K | — |
| Groupe la Francaise | 0 | -120 | $0 | -$569 | — |
| THOMPSON SIEGEL & WALMSLEY LLC | 0 | -29,780 | $0 | -$142 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
New & Closed Positions this quarter
Closed Positions
8 managers exited
Top five by prior-quarter value
- DIMENSIONAL FUND ADVISORS LP$148.2K
- CITADEL ADVISORS LLC$58.6K
- Squarepoint Ops LLC$48.7K
- Savvy Advisors, Inc.$47.6K
- Tower Research Capital LLC (TRC)$2.3K
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for SOPH against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.