New Positions
16 managers initiated
Top five by reported value
- Privium Fund Management B.V.$1.2M
- TWO SIGMA INVESTMENTS, LP$658.1K
- Walleye Capital LLC$316.4K
- RENAISSANCE TECHNOLOGIES LLC$296.3K
- Point72 Asset Management, L.P.$244.2K
Cartesian Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:RNAC
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
16 new22 added31 reduced14 exited
Total Institutional Holders
69
as of 2025-12-31
Top Holder
FMR LLC
$9.9M
Largest QoQ Increase
Privium Fund Management B.V.
+172,500 sh
Largest QoQ Decrease
FMR LLC
-788,794 sh
New Positions(16)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Privium Fund Management B.V. | 172,500 | +172,500 | $1.2M | +$1.2M | — |
| TWO SIGMA INVESTMENTS, LP | 91,278 | +91,278 | $658.1K | +$658.1K | — |
| Walleye Capital LLC | 43,878 | +43,878 | $316.4K | +$316.4K | — |
| RENAISSANCE TECHNOLOGIES LLC | 41,100 | +41,100 | $296.3K | +$296.3K | — |
| Point72 Asset Management, L.P. | 33,871 | +33,871 | $244.2K | +$244.2K | — |
| TWO SIGMA ADVISERS, LP | 24,808 | +24,808 | $178.9K | +$178.9K | — |
| AMERIPRISE FINANCIAL INC | 19,806 | +19,806 | $142.8K | +$142.8K | — |
| JANE STREET GROUP, LLC | 19,100 | +19,100 | $137.7K | +$137.7K | — |
| Squarepoint Ops LLC | 18,213 | +18,213 | $131.3K | +$131.3K | — |
| Jain Global LLC | 16,724 | +16,724 | $120.6K | +$120.6K | — |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 15,500 | +15,500 | $111.8K | +$111.8K | — |
| R Squared Ltd | 10,308 | +10,308 | $74.3K | +$74.3K | — |
| UBS ASSET MANAGEMENT AMERICAS INC | 516 | +516 | $3.7K | +$3.7K | — |
| JONES FINANCIAL COMPANIES LLLP | 200 | +200 | $1.4K | +$1.4K | — |
| PNC Financial Services Group, Inc. | 5 | +5 | $36 | +$36 | — |
| SageView Advisory Group, LLC | 3 | +3 | $22 | +$22 | — |
Added To(22)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 541,228 | +20,506 | $3.9M | -$1.4M | 3.9% |
| MILLENNIUM MANAGEMENT LLC | 164,366 | +139,009 | $1.2M | +$925.9K | 548.2% |
| BANK OF AMERICA CORP /DE/ | 113,092 | +99,023 | $815.4K | +$671.6K | 703.8% |
| GEODE CAPITAL MANAGEMENT, LLC | 255,539 | +13,710 | $1.8M | -$629.2K | 5.7% |
| Erste Asset Management GmbH | 271,705 | +11,694 | $2.0M | -$604.8K | 4.5% |
| STATE STREET CORP | 198,967 | +1,301 | $1.4M | -$585.6K | 0.7% |
| MARSHALL WACE, LLP | 178,140 | +93,334 | $1.3M | +$417.7K | 110.0% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 95,799 | +65,798 | $690.7K | +$384.1K | 219.3% |
| UBS Group AG | 67,341 | +57,393 | $485.5K | +$383.9K | 576.9% |
| 683 Capital Management, LLC | 280,000 | +50,000 | $2.0M | -$331.8K | 21.7% |
| BARCLAYS PLC | 30,675 | +12,833 | $318.7K | +$136.4K | 71.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 25,300 | +405 | $182.4K | -$72.0K | 1.6% |
| Bank of New York Mellon Corp | 25,241 | +1,050 | $182.0K | -$65.2K | 4.3% |
| MORGAN STANLEY | 23,294 | +4,320 | $167.9K | -$26.0K | 22.8% |
| Miller Financial Services LLC | 13,643 | +2,000 | $98.4K | -$20.6K | 17.2% |
| DEUTSCHE BANK AG\ | 8,112 | +688 | $58.5K | -$17.4K | 9.3% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 5,120 | +244 | $36.9K | -$12.9K | 5.0% |
| BNP PARIBAS ARBITRAGE, SNC | 2,414 | +174 | $17.4K | -$5.5K | 7.8% |
| WELLS FARGO & COMPANY/MN | 11,762 | +3,878 | $84.8K | +$4.2K | 49.2% |
| Tower Research Capital LLC (TRC) | 2,379 | +1,067 | $17.2K | +$3.7K | 81.3% |
| Sterling Capital Management LLC | 644 | +5 | $4.6K | -$1.9K | 0.8% |
| Russell Investments Group, Ltd. | 849 | +82 | $6.1K | -$1.7K | 10.7% |
Reduced(31)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| FMR LLC | 1,366,989 | -788,794 | $9.9M | -$12.2M | -36.6% |
| BlackRock, Inc. | 609,696 | -39,645 | $4.4M | -$2.2M | -6.1% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 60,200 | -36,330 | $434.0K | -$552.5K | -37.6% |
| CITADEL ADVISORS LLC | 79,785 | -6,739 | $575.3K | -$309.0K | -7.8% |
| NORTHERN TRUST CORP | 87,013 | -4,276 | $627.4K | -$305.6K | -4.7% |
| Royal Bank of Canada | 906 | -19,779 | $7.0K | -$214.0K | -95.6% |
| Ikarian Capital, LLC | 20,807 | -1,359 | $150.0K | -$76.5K | -6.1% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 25,000 | 0 | $180.3K | -$75.3K | 0.0% |
| XTX Topco Ltd | 10,238 | -16,021 | $73.8K | +$73.8K | -61.0% |
| Nuveen, LLC | 24,497 | 0 | $176.6K | -$73.7K | 0.0% |
| TWIN FOCUS CAPITAL PARTNERS, LLC | 19,500 | 0 | $140.6K | -$58.7K | 0.0% |
| RHUMBLINE ADVISERS | 12,139 | -995 | $87.5K | -$46.7K | -7.6% |
| ALLIANCEBERNSTEIN L.P. | 12,765 | 0 | $92.0K | -$38.4K | 0.0% |
| AlphaQuest LLC | 6,924 | 0 | $49.9K | -$20.8K | 0.0% |
| JPMORGAN CHASE & CO | 5,889 | -235 | $42.5K | -$20.1K | -3.8% |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,902 | 0 | $28.1K | -$11.7K | 0.0% |
| Police & Firemen's Retirement System of New Jersey | 2,939 | 0 | $21.2K | -$8.8K | 0.0% |
| CITIGROUP INC | 238 | -429 | $1.7K | -$5.1K | -64.3% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 645 | -122 | $4.7K | -$3.2K | -15.9% |
| ALERUS FINANCIAL NA | 1,000 | 0 | $7.2K | -$3.0K | 0.0% |
| Legal & General Group Plc | 938 | 0 | $6.8K | -$2.8K | 0.0% |
| ADVISOR GROUP HOLDINGS, INC. | 107 | -197 | $770 | -$2.3K | -64.8% |
| Ameritas Investment Partners, Inc. | 708 | 0 | $5.1K | -$2.1K | 0.0% |
| EverSource Wealth Advisors, LLC | 6 | -33 | $43 | -$356 | -84.6% |
| GSA CAPITAL PARTNERS LLP | 77,227 | -8,868 | $557 | -$323 | -10.3% |
| Optiver Holding B.V. | 80 | 0 | $577 | -$241 | 0.0% |
| Activest Wealth Management | 66 | 0 | $476 | -$199 | 0.0% |
| SBI Securities Co., Ltd. | 49 | -1 | $353 | -$158 | -2.0% |
| Parallel Advisors, LLC | 103 | 0 | $22 | -$9 | 0.0% |
| AMALGAMATED BANK | 330 | -26 | $2 | -$2 | -7.3% |
| CWM, LLC | 191 | -63 | $1 | -$2 | -24.8% |
Sold Out(14)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Siren, L.L.C. | 0 | -563,272 | $0 | -$5.8M | — |
| BIOIMPACT CAPITAL LLC | 0 | -380,000 | $0 | -$3.9M | — |
| Freestone Capital Holdings, LLC | 0 | -25,921 | $0 | -$264.9K | — |
| Virtus Investment Advisers, Inc. | 0 | -11,112 | $0 | -$113.6K | — |
| China Universal Asset Management Co., Ltd. | 0 | -4,558 | $0 | -$46.6K | — |
| Mirae Asset Global Investments Co., Ltd. | 0 | -1,005 | $0 | -$10.3K | — |
| GF FUND MANAGEMENT CO. LTD. | 0 | -549 | $0 | -$5.6K | — |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0 | -439 | $0 | -$4.5K | — |
| SRS Capital Advisors, Inc. | 0 | -111 | $0 | -$1.1K | — |
| NISA INVESTMENT ADVISORS, LLC | 0 | -107 | $0 | -$1.1K | — |
| Spire Wealth Management | 0 | -50 | $0 | -$511 | — |
| GAMMA Investing LLC | 0 | -15 | $0 | -$153 | — |
| Larson Financial Group LLC | 0 | -3 | $0 | -$31 | — |
| Daiwa Securities Group Inc. | 0 | -84 | $0 | -$1 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| FMR LLC | 1,366,989 | $9.9M | -788,794 | -36.6% |
| BlackRock, Inc. | 609,696 | $4.4M | -39,645 | -6.1% |
| VANGUARD GROUP INC | 541,228 | $3.9M | +20,506 | 3.9% |
| 683 Capital Management, LLC | 280,000 | $2.0M | +50,000 | 21.7% |
| Erste Asset Management GmbH | 271,705 | $2.0M | +11,694 | 4.5% |
| GEODE CAPITAL MANAGEMENT, LLC | 255,539 | $1.8M | +13,710 | 5.7% |
| STATE STREET CORP | 198,967 | $1.4M | +1,301 | 0.7% |
| MARSHALL WACE, LLP | 178,140 | $1.3M | +93,334 | 110.0% |
| Privium Fund Management B.V. | 172,500 | $1.2M | +172,500 | — |
| MILLENNIUM MANAGEMENT LLC | 164,366 | $1.2M | +139,009 | 548.2% |
| BANK OF AMERICA CORP /DE/ | 113,092 | $815.4K | +99,023 | 703.8% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 95,799 | $690.7K | +65,798 | 219.3% |
| TWO SIGMA INVESTMENTS, LP | 91,278 | $658.1K | +91,278 | — |
| NORTHERN TRUST CORP | 87,013 | $627.4K | -4,276 | -4.7% |
| CITADEL ADVISORS LLC | 79,785 | $575.3K | -6,739 | -7.8% |
| UBS Group AG | 67,341 | $485.5K | +57,393 | 576.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 60,200 | $434.0K | -36,330 | -37.6% |
| BARCLAYS PLC | 30,675 | $318.7K | +12,833 | 71.9% |
| Walleye Capital LLC | 43,878 | $316.4K | +43,878 | — |
| RENAISSANCE TECHNOLOGIES LLC | 41,100 | $296.3K | +41,100 | — |
New & Closed Positions this quarter
Closed Positions
14 managers exited
Top five by prior-quarter value
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for RNAC against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.