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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
Markets · Healthcare

Rapport Therapeutics, Inc. (RAPP)

NGM · Biotechnology

$41.96-0.17 (-0.39%)Quote refreshed

Sources: Yahoo Finance (quote, statistics) · SEC EDGAR (filings, insider trades, 13F holders) · company filings & press wires

Market Cap
$2.01B
P/E (TTM)
—
EPS
$-2.59
Div Yield
—
52W Range
$13.62–$44.28
Beta
0.95

Company overview

Next earnings: 2026-08-06(9d)

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

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Recent press releases

April 2026

3 months agoARSHealthcare

Rapport Therapeutics Reports Cash Runway and RAP-219 Trial Progress

RAPPRapport Therapeutics, Inc.

# 🧾 What This Document Is This is Rapport Therapeutics' **Annual Report to Shareholders (ARS)**. Think of it as the company's yearly "report card" and "state of the union" combined into one document, sent directly to its investors. It's designed to give a comprehensive, investor-friendly overview

Read summaryView on SEC EDGAR
3 months ago8-KHealthcare

RAPP reports 68% sustained seizure reduction with RAP-219 follow-up data

RAPPRapport Therapeutics, Inc.

# 📄 What This Document Is 📰 This filing is a detailed summary of results presented at a major medical conference, the 2026 American Academy of Neurology (AAN) Annual Meeting. It's not a formal SEC filing, but an official presentation of scientific data about the company's lead drug, RAP-219. Bec

Read summaryView on SEC EDGAR
2 recent filings shown in the timeline above. View all SEC filings →

Rapport Therapeutics, Inc. has no reported insider trades in the last 90 days.

Institutional holders

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As of 2025-12-31 · prior 2025-09-30
2,431,862 sh+55.1%
3,001,879 sh+23.9%
714,821 sh+92.3%
FMR LLC$215.8M
7,111,865 sh+2.8%
708,469 sh-32.7%
226,360 sh-59.4%
673,923 sh+66.8%

People at Rapport Therapeutics, Inc.

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Quarterly financials

Full financials →
Revenue trend
03/25
—
NI -$24.1M
06/25
—
NI -$26.7M
09/25
—
NI -$26.9M
RevenueNI = Net Income
EPS trend (diluted)
Latest: $-0.71
Prior: $-0.75
Revenue sparkline