- Sio Capital Management, LLC$1.8M
- GILPIN WEALTH MANAGEMENT, LLC$559.6K
- MARSHALL WACE, LLP$471.6K
- ADAR1 Capital Management, LLC$158.0K
- Vontobel Holding Ltd.$63.2K
Outlook Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:OTLK
Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.
New Positions(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Sio Capital Management, LLC | 1,125,400 | +1,125,400 | $1.8M | +$1.8M | — |
| GILPIN WEALTH MANAGEMENT, LLC | 354,200 | +354,200 | $559.6K | +$559.6K | — |
| MARSHALL WACE, LLP | 298,456 | +298,456 | $471.6K | +$471.6K | — |
| ADAR1 Capital Management, LLC | 100,000 | +100,000 | $158.0K | +$158.0K | — |
| Vontobel Holding Ltd. | 40,000 | +40,000 | $63.2K | +$63.2K | — |
| Sanctuary Advisors, LLC | 33,495 | +33,495 | $35.5K | +$35.5K | — |
| Tower Research Capital LLC (TRC) | 12,873 | +12,873 | $20.3K | +$20.3K | — |
| Squarepoint Ops LLC | 11,699 | +11,699 | $18.5K | +$18.5K | — |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 1,000 | +1,000 | $1.6K | +$1.6K | — |
| Fortitude Family Office, LLC | 424 | +424 | $670 | +$670 | — |
| IFP Advisors, Inc | 50 | +50 | $79 | +$79 | — |
Added To(23)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| Schonfeld Strategic Advisors LLC | 2,441,355 | +1,726,185 | $3.9M | +$3.1M | 241.4% |
| CITADEL ADVISORS LLC | 1,039,600 | +993,800 | $1.6M | +$1.6M | 2169.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 732,722 | +496,801 | $1.2M | +$907.6K | 210.6% |
| VANGUARD GROUP INC | 1,465,167 | +122,540 | $2.3M | +$891.8K | 9.1% |
| UBS Group AG | 209,540 | +161,426 | $331.1K | +$280.1K | 335.5% |
| BlackRock, Inc. | 404,542 | +34,808 | $639.2K | +$247.3K | 9.4% |
| JANE STREET GROUP, LLC | 161,562 | +121,237 | $255.3K | +$212.5K | 300.6% |
| STATE STREET CORP | 163,102 | +87,800 | $257.7K | +$177.9K | 116.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 316,464 | +10,169 | $500.1K | +$175.4K | 3.3% |
| SIMPLEX TRADING, LLC | 105,797 | +16,556 | $167.2K | +$167.1K | 18.6% |
| NORTHERN TRUST CORP | 67,390 | +41,321 | $106.5K | +$78.8K | 158.5% |
| GROUP ONE TRADING, L.P. | 36,997 | +20,164 | $58.5K | +$40.6K | 119.8% |
| XTX Topco Ltd | 30,224 | +19,214 | $47.8K | +$36.1K | 174.5% |
| GOLDMAN SACHS GROUP INC | 45,782 | +2,812 | $72.3K | +$26.8K | 6.5% |
| Christensen, King & Associates Investment Services, Inc. | 28,327 | +1,119 | $44.8K | +$15.9K | 4.1% |
| HARBOUR INVESTMENTS, INC. | 10,152 | +9,331 | $16.0K | +$15.2K | 1136.5% |
| PNC Financial Services Group, Inc. | 15,000 | +3,472 | $23.7K | +$11.5K | 30.1% |
| Vanguard Personalized Indexing Management, LLC | 15,605 | +1,713 | $24.7K | +$9.9K | 12.3% |
| MORGAN STANLEY | 6,024 | +5,249 | $9.5K | +$8.7K | 677.3% |
| WELLS FARGO & COMPANY/MN | 2,480 | +1,070 | $3.9K | +$2.4K | 75.9% |
| Prestige Wealth Management Group LLC | 372 | +310 | $1.1K | +$1.1K | 500.0% |
| FMR LLC | 606 | +500 | $957 | +$845 | 471.7% |
| BARCLAYS PLC | 101 | +100 | $162 | +$161 | 10000.0% |
Reduced(22)
Sold Out(11)
| Manager | Shares | Δ Shares | Value | Δ Value | % Δ |
|---|---|---|---|---|---|
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | -9,097 | $0 | -$50.5K | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | -36,060 | $0 | -$44.0K | — |
| TWO SIGMA SECURITIES, LLC | 0 | -35,664 | $0 | -$37.8K | — |
| Russell Investments Group, Ltd. | 0 | -15,498 | $0 | -$16.4K | — |
| Qube Research & Technologies Ltd | 0 | -13,347 | $0 | -$14.1K | — |
| OPPENHEIMER & CO INC | 0 | -13,000 | $0 | -$13.8K | — |
| TWO SIGMA INVESTMENTS, LP | 0 | -11,356 | $0 | -$12.0K | — |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | -5,815 | $0 | -$6.2K | — |
| Cubist Systematic Strategies, LLC | 0 | -5,295 | $0 | -$5.6K | — |
| Wealthspire Advisors, LLC | 0 | -300 | $0 | -$318 | — |
| Tradewinds Capital Management, LLC | 0 | -100 | $0 | -$106 | — |
Top Holders by reported value
Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.
| Manager | Shares | $ Value | Δ Shares | QoQ % |
|---|---|---|---|---|
| Schonfeld Strategic Advisors LLC | 2,441,355 | $3.9M | +1,726,185 | 241.4% |
| VANGUARD GROUP INC | 1,465,167 | $2.3M | +122,540 | 9.1% |
| Sio Capital Management, LLC | 1,125,400 | $1.8M | +1,125,400 | — |
| CITADEL ADVISORS LLC | 1,039,600 | $1.6M | +993,800 | 2169.9% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 732,722 | $1.2M | +496,801 | 210.6% |
| BlackRock, Inc. | 404,542 | $639.2K | +34,808 | 9.4% |
| GILPIN WEALTH MANAGEMENT, LLC | 354,200 | $559.6K | +354,200 | — |
| GEODE CAPITAL MANAGEMENT, LLC | 316,464 | $500.1K | +10,169 | 3.3% |
| MARSHALL WACE, LLP | 298,456 | $471.6K | +298,456 | — |
| UBS Group AG | 209,540 | $331.1K | +161,426 | 335.5% |
| MILLENNIUM MANAGEMENT LLC | 164,498 | $259.9K | -30,085 | -15.5% |
| STATE STREET CORP | 163,102 | $257.7K | +87,800 | 116.6% |
| JANE STREET GROUP, LLC | 161,562 | $255.3K | +121,237 | 300.6% |
| COMMONWEALTH EQUITY SERVICES, LLC | 112,500 | $177.8K | -651 | -0.6% |
| SIMPLEX TRADING, LLC | 105,797 | $167.2K | +16,556 | 18.6% |
| ADAR1 Capital Management, LLC | 100,000 | $158.0K | +100,000 | — |
| SCOTIA CAPITAL INC. | 73,989 | $116.9K | 0 | 0.0% |
| NORTHERN TRUST CORP | 67,390 | $106.5K | +41,321 | 158.5% |
| LVW Advisors, LLC | 48,235 | $76.2K | 0 | 0.0% |
| GOLDMAN SACHS GROUP INC | 45,782 | $72.3K | +2,812 | 6.5% |
New & Closed Positions this quarter
Methodology
Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.
Quarter-over-quarter deltas compare each manager's most recently reported share count for OTLK against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.
Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.