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VOL. XII · NO. 117Established MMXIV · George Town, Grand CaymanAtlantic Edition · $4.50

The Cayman Journal

Finance · Business · Technology · Caribbean & Global Affairs
13F Institutional Ownership · OTLK

Outlook Therapeutics Inc NASDAQ NMS - GLOBAL MARKET:OTLK

Institutional holders, quarter-over-quarter share deltas, and new and closed positions disclosed in Form 13F. Period 2025-12-31 · prior 2025-09-30.

11 new23 added22 reduced11 exited

New Positions(11)

ManagerSharesΔ SharesValueΔ Value% Δ
Sio Capital Management, LLC1,125,400+1,125,400$1.8M+$1.8M
GILPIN WEALTH MANAGEMENT, LLC354,200+354,200$559.6K+$559.6K
MARSHALL WACE, LLP298,456+298,456$471.6K+$471.6K
ADAR1 Capital Management, LLC100,000+100,000$158.0K+$158.0K
Vontobel Holding Ltd.40,000+40,000$63.2K+$63.2K
Sanctuary Advisors, LLC33,495+33,495$35.5K+$35.5K
Tower Research Capital LLC (TRC)12,873+12,873$20.3K+$20.3K
Squarepoint Ops LLC11,699+11,699$18.5K+$18.5K
INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC1,000+1,000$1.6K+$1.6K
Fortitude Family Office, LLC424+424$670+$670
IFP Advisors, Inc50+50$79+$79

Added To(23)

ManagerSharesΔ SharesValueΔ Value% Δ
Schonfeld Strategic Advisors LLC2,441,355+1,726,185$3.9M+$3.1M241.4%
CITADEL ADVISORS LLC1,039,600+993,800$1.6M+$1.6M2169.9%
SUSQUEHANNA INTERNATIONAL GROUP, LLP732,722+496,801$1.2M+$907.6K210.6%
VANGUARD GROUP INC1,465,167+122,540$2.3M+$891.8K9.1%
UBS Group AG209,540+161,426$331.1K+$280.1K335.5%
BlackRock, Inc.404,542+34,808$639.2K+$247.3K9.4%
JANE STREET GROUP, LLC161,562+121,237$255.3K+$212.5K300.6%
STATE STREET CORP163,102+87,800$257.7K+$177.9K116.6%
GEODE CAPITAL MANAGEMENT, LLC316,464+10,169$500.1K+$175.4K3.3%
SIMPLEX TRADING, LLC105,797+16,556$167.2K+$167.1K18.6%
NORTHERN TRUST CORP67,390+41,321$106.5K+$78.8K158.5%
GROUP ONE TRADING, L.P.36,997+20,164$58.5K+$40.6K119.8%
XTX Topco Ltd30,224+19,214$47.8K+$36.1K174.5%
GOLDMAN SACHS GROUP INC45,782+2,812$72.3K+$26.8K6.5%
Christensen, King & Associates Investment Services, Inc.28,327+1,119$44.8K+$15.9K4.1%
HARBOUR INVESTMENTS, INC.10,152+9,331$16.0K+$15.2K1136.5%
PNC Financial Services Group, Inc.15,000+3,472$23.7K+$11.5K30.1%
Vanguard Personalized Indexing Management, LLC15,605+1,713$24.7K+$9.9K12.3%
MORGAN STANLEY6,024+5,249$9.5K+$8.7K677.3%
WELLS FARGO & COMPANY/MN2,480+1,070$3.9K+$2.4K75.9%
Prestige Wealth Management Group LLC372+310$1.1K+$1.1K500.0%
FMR LLC606+500$957+$845471.7%
BARCLAYS PLC101+100$162+$16110000.0%

Reduced(22)

ManagerSharesΔ SharesValueΔ Value% Δ
COMMONWEALTH EQUITY SERVICES, LLC112,500-651$177.8K+$177.6K-0.6%
BANK OF AMERICA CORP /DE/128-90,347$203-$95.7K-99.8%
MILLENNIUM MANAGEMENT LLC164,498-30,085$259.9K+$53.6K-15.5%
SCOTIA CAPITAL INC.73,9890$116.9K+$38.5K0.0%
Royal Bank of Canada687-24,435$1.0K-$38.0K-97.3%
LVW Advisors, LLC48,2350$76.2K+$25.1K0.0%
CITIGROUP INC1,554-14,424$2.5K-$14.5K-90.3%
TUDOR INVESTMENT CORP ET AL10,000-15,100$15.8K-$10.8K-60.1%
Flower City Capital20,0000$31.6K+$10.4K0.0%
ADVISOR GROUP HOLDINGS, INC.8,9730$14.2K+$4.7K0.0%
LPL Financial LLC21,794-6,630$34.4K+$4.3K-23.3%
JONES FINANCIAL COMPANIES LLLP2,5000$4.0K+$1.5K0.0%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO2,1250$3.4K+$1.1K0.0%
Federation des caisses Desjardins du Quebec1,3120$2.1K+$7090.0%
EverSource Wealth Advisors, LLC6960$1.1K+$3620.0%
BNP PARIBAS ARBITRAGE, SNC3050$482+$1590.0%
SBI Securities Co., Ltd.2100$332+$1090.0%
ARMSTRONG ADVISORY GROUP, INC1790$283+$930.0%
Larson Financial Group LLC1000$158+$520.0%
JPMORGAN CHASE & CO150$24+$80.0%
Steward Partners Investment Advisory, LLC140$22+$70.0%
CWM, LLC2830$0$00.0%

Sold Out(11)

ManagerSharesΔ SharesValueΔ Value% Δ
NEW YORK STATE COMMON RETIREMENT FUND0-9,097$0-$50.5K
CHARLES SCHWAB INVESTMENT MANAGEMENT INC0-36,060$0-$44.0K
TWO SIGMA SECURITIES, LLC0-35,664$0-$37.8K
Russell Investments Group, Ltd.0-15,498$0-$16.4K
Qube Research & Technologies Ltd0-13,347$0-$14.1K
OPPENHEIMER & CO INC0-13,000$0-$13.8K
TWO SIGMA INVESTMENTS, LP0-11,356$0-$12.0K
Point72 Asia (Singapore) Pte. Ltd.0-5,815$0-$6.2K
Cubist Systematic Strategies, LLC0-5,295$0-$5.6K
Wealthspire Advisors, LLC0-300$0-$318
Tradewinds Capital Management, LLC0-100$0-$106

Top Holders by reported value

Ranked by the dollar value reported on the latest Form 13F. Share counts reflect long positions as of 2025-12-31.

ManagerShares$ ValueΔ SharesQoQ %
Schonfeld Strategic Advisors LLC2,441,355$3.9M+1,726,185241.4%
VANGUARD GROUP INC1,465,167$2.3M+122,5409.1%
Sio Capital Management, LLC1,125,400$1.8M+1,125,400
CITADEL ADVISORS LLC1,039,600$1.6M+993,8002169.9%
SUSQUEHANNA INTERNATIONAL GROUP, LLP732,722$1.2M+496,801210.6%
BlackRock, Inc.404,542$639.2K+34,8089.4%
GILPIN WEALTH MANAGEMENT, LLC354,200$559.6K+354,200
GEODE CAPITAL MANAGEMENT, LLC316,464$500.1K+10,1693.3%
MARSHALL WACE, LLP298,456$471.6K+298,456
UBS Group AG209,540$331.1K+161,426335.5%
MILLENNIUM MANAGEMENT LLC164,498$259.9K-30,085-15.5%
STATE STREET CORP163,102$257.7K+87,800116.6%
JANE STREET GROUP, LLC161,562$255.3K+121,237300.6%
COMMONWEALTH EQUITY SERVICES, LLC112,500$177.8K-651-0.6%
SIMPLEX TRADING, LLC105,797$167.2K+16,55618.6%
ADAR1 Capital Management, LLC100,000$158.0K+100,000
SCOTIA CAPITAL INC.73,989$116.9K00.0%
NORTHERN TRUST CORP67,390$106.5K+41,321158.5%
LVW Advisors, LLC48,235$76.2K00.0%
GOLDMAN SACHS GROUP INC45,782$72.3K+2,8126.5%

New & Closed Positions this quarter

Methodology

Form 13F is the SEC's quarterly disclosure for institutional investment managers exercising discretion over $100 million or more in qualifying U.S. equity securities. Managers must file within 45 days of each calendar quarter end, which is why holdings shown here reflect a snapshot at the period date — not real-time positioning.

Quarter-over-quarter deltas compare each manager's most recently reported share count for OTLK against its prior-quarter count. New positions are entries where the prior count was zero; closed positions are entries where the current count is zero. Amendments (13F-HR/A) replace prior filings for the same period.

Source: SEC EDGAR Form 13F (XML information tables). Dollar values are as reported by the manager and may use mid-quarter pricing conventions. CUSIP-to-ticker resolution is best-effort.